ATE458835T1 - Verfahren und zusammensetzungen zum nachweis und zur analyse von nukleinsäuren mittels signalverstärkung - Google Patents

Verfahren und zusammensetzungen zum nachweis und zur analyse von nukleinsäuren mittels signalverstärkung

Info

Publication number
ATE458835T1
ATE458835T1 AT06705275T AT06705275T ATE458835T1 AT E458835 T1 ATE458835 T1 AT E458835T1 AT 06705275 T AT06705275 T AT 06705275T AT 06705275 T AT06705275 T AT 06705275T AT E458835 T1 ATE458835 T1 AT E458835T1
Authority
AT
Austria
Prior art keywords
dna
detection system
signal amplification
cationic polythiophene
complexation
Prior art date
Application number
AT06705275T
Other languages
English (en)
Inventor
Mario Leclerc
Hoang-Anh Ho
Original Assignee
Ca Nat Research Council
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ca Nat Research Council filed Critical Ca Nat Research Council
Application granted granted Critical
Publication of ATE458835T1 publication Critical patent/ATE458835T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/682—Signal amplification
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT06705275T 2005-03-03 2006-03-03 Verfahren und zusammensetzungen zum nachweis und zur analyse von nukleinsäuren mittels signalverstärkung ATE458835T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65771705P 2005-03-03 2005-03-03
PCT/CA2006/000322 WO2006092063A1 (en) 2005-03-03 2006-03-03 Methods and compositions for the detection and analysis of nucleic acids by signal amplification

Publications (1)

Publication Number Publication Date
ATE458835T1 true ATE458835T1 (de) 2010-03-15

Family

ID=36940822

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06705275T ATE458835T1 (de) 2005-03-03 2006-03-03 Verfahren und zusammensetzungen zum nachweis und zur analyse von nukleinsäuren mittels signalverstärkung

Country Status (9)

Country Link
US (1) US7972860B2 (de)
EP (1) EP1853722B1 (de)
JP (1) JP4933458B2 (de)
AT (1) ATE458835T1 (de)
AU (1) AU2006220201B8 (de)
CA (1) CA2598096C (de)
DE (1) DE602006012455D1 (de)
ES (1) ES2341669T3 (de)
WO (1) WO2006092063A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10001475B2 (en) 2002-06-20 2018-06-19 The Regents Of The University Of California Light harvesting multichromophore compositions and methods of using the same
US9371559B2 (en) 2002-06-20 2016-06-21 The Regents Of The University Of California Compositions for detection and analysis of polynucleotides using light harvesting multichromophores
US7144950B2 (en) 2003-09-17 2006-12-05 The Regents Of The University Of California Conformationally flexible cationic conjugated polymers
CA2497152C (en) 2002-08-26 2016-06-07 The Regents Of The University Of California Methods and compositions for detection and analysis of polynucleotides using light harvesting multichromophores
CN1771335A (zh) 2003-02-13 2006-05-10 加州大学评议会 使用集光多生色团检测和分析多核苷酸－结合蛋白相互作用的方法和组合物
WO2006074471A2 (en) 2005-01-10 2006-07-13 The Regents Of The University Of California Cationic conjugated polymers suitable for strand-specific polynucleotide detection in homogeneous and solid state assays
WO2006074482A2 (en) 2005-01-10 2006-07-13 The Regents Of The University Of California Methods and kits for strand-specific polynucleotide detection with cationic multichromophores
US7666594B2 (en) 2005-01-31 2010-02-23 The Regents Of The University Of California Methods for assaying a sample for an aggregant
CA2676442A1 (en) * 2006-05-11 2007-11-22 Universite Laval Methods for detection of target on responsive polymeric biochips
JP5420414B2 (ja) 2006-10-06 2014-02-19 シリゲン グループ リミテッド 指向性バイオマーカシグナル増幅用の蛍光方法および材料
US8765369B2 (en) 2007-07-13 2014-07-01 National Research Council Of Canada Ultrasensitive detection of target using target-ready particles
SG177355A1 (en) 2009-06-26 2012-02-28 Sirigen Inc Signal amplified biological detection with conjugated polymers
ES2977359T3 (es) 2010-01-19 2024-08-22 Sirigen Ii Ltd Nuevos reactivos para la amplificación dirigida de la señal de un biomarcador
CN112444546B (zh) * 2019-09-03 2022-07-01 华中农业大学 一种用于检测寡核苷酸的电化学发光传感器及其制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2703359B1 (fr) * 1993-03-31 1995-06-23 Cis Bio Int Copolymère nucléotide(s)/polymère conducteur électronique ; son procédé de préparation et son utilisation .
US5681702A (en) 1994-08-30 1997-10-28 Chiron Corporation Reduction of nonspecific hybridization by using novel base-pairing schemes
JP2000515515A (ja) 1996-07-22 2000-11-21 ユニベルシテ・ド・モントリオール 酸で自己ドーピングされた新規な高電導性ポリチオフェン類
WO2000066790A1 (en) 1999-05-05 2000-11-09 The Regents Of The University Of California Method for detecting biological agents
WO2002081735A2 (en) 2001-04-05 2002-10-17 Infectio Diagnostic (I.D.I.), Inc. Detection of negatively charged polymers using water-soluble, cationic, polythiophene derivatives
DE60333646D1 (de) * 2002-06-20 2010-09-16 Univ California Verfahren und zusammensetzungen zum nachweis und zur analyse von polynukleotiden unter verwendung von licht einfangenden multichromophoren
CA2497152C (en) * 2002-08-26 2016-06-07 The Regents Of The University Of California Methods and compositions for detection and analysis of polynucleotides using light harvesting multichromophores
US20040142206A1 (en) 2003-01-17 2004-07-22 Bazan Guillermo C. Binaphthol based chromophores for the fabrication of blue organic light emitting diodes
CN1771335A (zh) 2003-02-13 2006-05-10 加州大学评议会 使用集光多生色团检测和分析多核苷酸－结合蛋白相互作用的方法和组合物
CA2430910A1 (en) * 2003-06-03 2004-12-03 Infectio Diagnostic (I.D.I.) Inc. Optical sensors based on hybrid aptamer/conjugated polymer complexes

Also Published As

Publication number Publication date
US20090215187A1 (en) 2009-08-27
AU2006220201A1 (en) 2006-09-08
CA2598096A1 (en) 2006-09-08
WO2006092063A1 (en) 2006-09-08
AU2006220201B8 (en) 2011-11-17
CA2598096C (en) 2014-02-11
ES2341669T3 (es) 2010-06-24
JP4933458B2 (ja) 2012-05-16
EP1853722A1 (de) 2007-11-14
JP2008535478A (ja) 2008-09-04
DE602006012455D1 (de) 2010-04-08
EP1853722A4 (de) 2009-02-18
AU2006220201B2 (en) 2011-08-04
EP1853722B1 (de) 2010-02-24
US7972860B2 (en) 2011-07-05

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