WO2005094902A3 - Agent de contraste destine a l'imagerie medicale - Google Patents

Agent de contraste destine a l'imagerie medicale Download PDF

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Publication number
WO2005094902A3
WO2005094902A3 PCT/IB2005/051021 IB2005051021W WO2005094902A3 WO 2005094902 A3 WO2005094902 A3 WO 2005094902A3 IB 2005051021 W IB2005051021 W IB 2005051021W WO 2005094902 A3 WO2005094902 A3 WO 2005094902A3
Authority
WO
WIPO (PCT)
Prior art keywords
optical imaging
contrast agent
nanoparticles
luminescent substances
core
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2005/051021
Other languages
English (en)
Other versions
WO2005094902A2 (fr
Inventor
Claus Feldmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Philips Intellectual Property and Standards GmbH
Koninklijke Philips NV
Original Assignee
Philips Intellectual Property and Standards GmbH
Koninklijke Philips Electronics NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Philips Intellectual Property and Standards GmbH, Koninklijke Philips Electronics NV filed Critical Philips Intellectual Property and Standards GmbH
Publication of WO2005094902A2 publication Critical patent/WO2005094902A2/fr
Publication of WO2005094902A3 publication Critical patent/WO2005094902A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K11/00—Luminescent materials, e.g. electroluminescent or chemiluminescent
    • C09K11/08—Luminescent materials, e.g. electroluminescent or chemiluminescent containing inorganic luminescent materials
    • C09K11/77—Luminescent materials, e.g. electroluminescent or chemiluminescent containing inorganic luminescent materials containing rare earth metals
    • C09K11/7766—Luminescent materials, e.g. electroluminescent or chemiluminescent containing inorganic luminescent materials containing rare earth metals containing two or more rare earth metals
    • C09K11/7774—Aluminates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0063—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0063—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres
    • A61K49/0065—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the luminescent/fluorescent agent having itself a special physical form, e.g. gold nanoparticle
    • A61K49/0067—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the luminescent/fluorescent agent having itself a special physical form, e.g. gold nanoparticle quantum dots, fluorescent nanocrystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0063—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres
    • A61K49/0069—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form
    • A61K49/0089—Particulate, powder, adsorbate, bead, sphere
    • A61K49/0091—Microparticle, microcapsule, microbubble, microsphere, microbead, i.e. having a size or diameter higher or equal to 1 micrometer
    • A61K49/0093—Nanoparticle, nanocapsule, nanobubble, nanosphere, nanobead, i.e. having a size or diameter smaller than 1 micrometer, e.g. polymeric nanoparticle
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K11/00—Luminescent materials, e.g. electroluminescent or chemiluminescent
    • C09K11/08—Luminescent materials, e.g. electroluminescent or chemiluminescent containing inorganic luminescent materials
    • C09K11/57—Luminescent materials, e.g. electroluminescent or chemiluminescent containing inorganic luminescent materials containing manganese or rhenium
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K11/00—Luminescent materials, e.g. electroluminescent or chemiluminescent
    • C09K11/08—Luminescent materials, e.g. electroluminescent or chemiluminescent containing inorganic luminescent materials
    • C09K11/74—Luminescent materials, e.g. electroluminescent or chemiluminescent containing inorganic luminescent materials containing arsenic, antimony or bismuth

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Materials Engineering (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nanotechnology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Luminescent Compositions (AREA)

Abstract

L'invention concerne un agent de contraste destiné à l'imagerie optique comprenant des particules (1) comprenant au moins un noyau (2), ledit noyau comprenant des substances luminescentes qui absorbent et émettent un rayonnement électromagnétique à des longueurs d'ondes différentes.
PCT/IB2005/051021 2004-04-01 2005-03-24 Agent de contraste destine a l'imagerie medicale Ceased WO2005094902A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04101351 2004-04-01
EP04101351.7 2004-04-01

Publications (2)

Publication Number Publication Date
WO2005094902A2 WO2005094902A2 (fr) 2005-10-13
WO2005094902A3 true WO2005094902A3 (fr) 2006-05-26

Family

ID=34961991

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2005/051021 Ceased WO2005094902A2 (fr) 2004-04-01 2005-03-24 Agent de contraste destine a l'imagerie medicale

Country Status (1)

Country Link
WO (1) WO2005094902A2 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1920784A1 (fr) * 2006-11-13 2008-05-14 Koninklijke Philips Electronics N.V. Sensibilisateurs de radiation pour la thérapie par rayonnements ionisants et pour l'imagerie
DE102007039335A1 (de) * 2007-08-20 2009-02-26 Henkel Ag & Co. Kgaa Lumineszierende Kompositmaterialien
CN104178160A (zh) * 2013-05-22 2014-12-03 海洋王照明科技股份有限公司 铈铽双掺杂氮硅镧发光材料、制备方法及其应用
US10124072B2 (en) 2013-09-18 2018-11-13 Caliper Life Sciences, Inc. In-vivo reactive species imaging
US9642923B2 (en) * 2014-02-24 2017-05-09 Verily Life Sciences Llc Engineered particles with polarization contrast and alignment control for enhanced imaging
KR102379752B1 (ko) * 2020-08-19 2022-03-28 국민대학교산학협력단 X-선 감쇠 기반 생체 이미징용 나노입자 및 조성물

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5893999A (en) * 1993-09-13 1999-04-13 Kabushiki Kaisha Toshiba Ultrafine inorganic phosphor, specifically binding material labeled with this phosphor, and detection method using this specific binding material
WO2001086299A2 (fr) * 2000-05-05 2001-11-15 Bayer Aktiengesellschaft Nanoparticules dopees servant de marqueurs biologiques
WO2003037788A1 (fr) * 2001-11-01 2003-05-08 Oxonica Limited Nanoparticules luminescentes hydrosolubles
WO2003038011A2 (fr) * 2001-11-01 2003-05-08 Oxonica Limited Nanomateriaux luminescents
US6699723B1 (en) * 1997-11-25 2004-03-02 The Regents Of The University Of California Organo luminescent semiconductor nanocrystal probes for biological applications and process for making and using such probes
WO2004018590A1 (fr) * 2002-08-20 2004-03-04 Oxonica Limited Composes luminescents
WO2005051846A2 (fr) * 2003-11-24 2005-06-09 Universite Claude Bernard Lyon I Procede de preparation d'une poudre submicronique, nanostructuree, de sesquioxyde, oxohydroxyde, hydroxyde ou oxyde mixte de terre rare
WO2005058360A2 (fr) * 2003-12-17 2005-06-30 Philips Intellectual Property & Standards Gmbh Radiotherapie et imagerie medicale au moyen de nanoparticules emettant des rayons ultraviolets

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5893999A (en) * 1993-09-13 1999-04-13 Kabushiki Kaisha Toshiba Ultrafine inorganic phosphor, specifically binding material labeled with this phosphor, and detection method using this specific binding material
US6699723B1 (en) * 1997-11-25 2004-03-02 The Regents Of The University Of California Organo luminescent semiconductor nanocrystal probes for biological applications and process for making and using such probes
WO2001086299A2 (fr) * 2000-05-05 2001-11-15 Bayer Aktiengesellschaft Nanoparticules dopees servant de marqueurs biologiques
WO2003037788A1 (fr) * 2001-11-01 2003-05-08 Oxonica Limited Nanoparticules luminescentes hydrosolubles
WO2003038011A2 (fr) * 2001-11-01 2003-05-08 Oxonica Limited Nanomateriaux luminescents
WO2004018590A1 (fr) * 2002-08-20 2004-03-04 Oxonica Limited Composes luminescents
WO2005051846A2 (fr) * 2003-11-24 2005-06-09 Universite Claude Bernard Lyon I Procede de preparation d'une poudre submicronique, nanostructuree, de sesquioxyde, oxohydroxyde, hydroxyde ou oxyde mixte de terre rare
WO2005058360A2 (fr) * 2003-12-17 2005-06-30 Philips Intellectual Property & Standards Gmbh Radiotherapie et imagerie medicale au moyen de nanoparticules emettant des rayons ultraviolets

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
FELDMANN C ET AL: "INORGANIC LUMINESCENT MATERIALS: 100 YEARS OF RESEARCH AND APPLICATION", ADVANCED FUNCTIONAL MATERIALS, WILEY VCH, WIENHEIM, DE, vol. 13, no. 7, July 2003 (2003-07-01), pages 511 - 516, XP001164632, ISSN: 1616-301X *
TORCHILIN V P: "TAT PEPTIDE-MODIFIED LIPOSOMES FOR INTRACELLULAR DELIVERY OF DRUGS AND DNA", CELLULAR AND MOLECULAR BIOLOGY LETTERS, UNIVERSITY OF WROCAW. INSTITUTE OF BIOCHEMISTRY, WROCAW, PL, vol. 7, no. 2, 2002, pages 265 - 267, XP008061723, ISSN: 1425-8153 *
ZIJLMANS H J M A A ET AL: "Detection of cell and tissue surface antigens using up-converting phosphors: A new reporter technology", ANALYTICAL BIOCHEMISTRY, ACADEMIC PRESS, SAN DIEGO, CA, US, vol. 267, no. 1, 1 February 1999 (1999-02-01), pages 30 - 36, XP002185942, ISSN: 0003-2697 *

Also Published As

Publication number Publication date
WO2005094902A2 (fr) 2005-10-13

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