WO2006016237A3 - Dérivés hétérocycliques faisant office d’agents anti-inflammatoires - Google Patents

Dérivés hétérocycliques faisant office d’agents anti-inflammatoires Download PDF

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Publication number
WO2006016237A3
WO2006016237A3 PCT/IB2005/002292 IB2005002292W WO2006016237A3 WO 2006016237 A3 WO2006016237 A3 WO 2006016237A3 IB 2005002292 W IB2005002292 W IB 2005002292W WO 2006016237 A3 WO2006016237 A3 WO 2006016237A3
Authority
WO
WIPO (PCT)
Prior art keywords
inflammatory
compounds
heterocyclic derivatives
inflammatory agents
psoriasis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2005/002292
Other languages
English (en)
Other versions
WO2006016237A2 (fr
Inventor
Venkata P Palle
Ashwani Kumar Verma
Mohammad Salman
Rakesh Kumar Singh
Yogesh Bhaskarrao Waman
Geeta Sharma
Abhijit Ray
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ranbaxy Laboratories Ltd
Original Assignee
Ranbaxy Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ranbaxy Laboratories Ltd filed Critical Ranbaxy Laboratories Ltd
Publication of WO2006016237A2 publication Critical patent/WO2006016237A2/fr
Publication of WO2006016237A3 publication Critical patent/WO2006016237A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La présente invention porte sur certains dérivés hétérocycliques faisant office d’agents anti-inflammatoires. Les composés de la présente invention peuvent servir à l’inhibition et/ou la prévention des inflammations et des pathologies associées, comme les maladies inflammatoires et auto-immunes comme l’état septique, l‘arthrite rhumatismale, les gastroentérites, le diabète de type-1, l’asthme, les troubles pulmonaires obstructifs chroniques, le rejet d’organes transplantés et le psoriasis. La présente invention porte également sur des compositions pharmacologiques contenant les composés divulgués ici et les procédés de traitement et/ou de prévention de l’état septique, de l‘arthrite rhumatismale, des gastroentérites, du diabète de type-1, de l’asthme, des troubles pulmonaires obstructifs chroniques, du rejet d’organes transplantés et du psoriasis et d’autres troubles inflammatoires et/ou auto-immunes à l’aide des composés.
PCT/IB2005/002292 2004-08-04 2005-08-02 Dérivés hétérocycliques faisant office d’agents anti-inflammatoires Ceased WO2006016237A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US59862104P 2004-08-04 2004-08-04
US60/598,621 2004-08-04

Publications (2)

Publication Number Publication Date
WO2006016237A2 WO2006016237A2 (fr) 2006-02-16
WO2006016237A3 true WO2006016237A3 (fr) 2006-05-26

Family

ID=35839645

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2005/002292 Ceased WO2006016237A2 (fr) 2004-08-04 2005-08-02 Dérivés hétérocycliques faisant office d’agents anti-inflammatoires

Country Status (1)

Country Link
WO (1) WO2006016237A2 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080207659A1 (en) 2007-02-15 2008-08-28 Asit Kumar Chakraborti Inhibitors of phosphodiesterase type 4
NZ579645A (en) 2007-03-14 2012-01-12 Ranbaxy Lab Ltd Pyrazolo (3, 4-b) pyridine derivatives as phosphodiesterase inhibitors
CA2737291C (fr) 2008-09-18 2013-04-16 Nippon Soda Co., Ltd. Compose heterocyclique contenant de l'azote et agent de lutte contre les animaux nuisibles
EA024512B1 (ru) 2011-03-31 2016-09-30 Байер Интеллектуэль Проперти Гмбх Гербицидно и фунгицидно действующие 3-фенилизоксазолин-5-карбоксамиды и 3-фенилизоксазолин-5-тиоамиды
US11613522B2 (en) 2017-06-13 2023-03-28 Bayer Aktiengesellschaft Herbicidally active 3-phenylisoxazoline-5-carboxamides of tetrahydro- and dihydrofurancarboxamides
DK3638665T3 (da) 2017-06-13 2021-10-11 Bayer Ag Herbicidt virksomme 3-phenylisoxazolin-5-carboxamider af tetrahydro- og dihydrofurancarboxylsyrer og -estere
JP7198519B2 (ja) 2017-08-17 2023-01-04 バイエル・アクチエンゲゼルシヤフト シクロペンチルカルボン酸類及びエステル類の除草活性３－フェニル－５－トリフルオロメチルイソオキサゾリン－５－カルボキサミド類
CA3089286A1 (fr) 2018-01-25 2019-08-01 Bayer Aktiengesellschaft 3-phenyl-isoxazoline-5-carboxamides de derives d'acide cyclopentenyl-carboxylique a action herbicide
ES2950189T3 (es) 2019-03-12 2023-10-05 Bayer Ag 3-fenilisoxazolina-5-carboxamidas de ésteres de ácido ciclopentenilcarboxílico que contienen s herbicidas

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4407134A1 (de) * 1994-03-04 1995-09-07 Thomae Gmbh Dr K Benzylpiperazine, deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung
WO1998046590A1 (fr) * 1997-04-17 1998-10-22 Takeda Chemical Industries, Ltd. Composition thermogenique et composes thermogeniques a base de benzazepine
WO2000012074A2 (fr) * 1998-08-28 2000-03-09 Scios Inc. INHIBITEURS DE p38-α KINASE
WO2001064676A2 (fr) * 2000-02-28 2001-09-07 Scios, Inc. INHIBITEURS DE LA P38-α KINASE
WO2002026720A2 (fr) * 2000-09-29 2002-04-04 Millennium Pharmaceuticals, Inc. INHIBITEURS DE FACTOR Xa A BASE DE PIPERAZINE

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4407134A1 (de) * 1994-03-04 1995-09-07 Thomae Gmbh Dr K Benzylpiperazine, deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung
WO1998046590A1 (fr) * 1997-04-17 1998-10-22 Takeda Chemical Industries, Ltd. Composition thermogenique et composes thermogeniques a base de benzazepine
WO2000012074A2 (fr) * 1998-08-28 2000-03-09 Scios Inc. INHIBITEURS DE p38-α KINASE
WO2001064676A2 (fr) * 2000-02-28 2001-09-07 Scios, Inc. INHIBITEURS DE LA P38-α KINASE
WO2002026720A2 (fr) * 2000-09-29 2002-04-04 Millennium Pharmaceuticals, Inc. INHIBITEURS DE FACTOR Xa A BASE DE PIPERAZINE

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
SPYCHALA, JAROSLAW: "A general synthesis of diaryl cyclic diamidines", TETRAHEDRON LETTERS , 40(14), 2841-2844 CODEN: TELEAY; ISSN: 0040-4039, 1999, XP004159452 *
TAO, BIN ET AL: "Novel bisbenzamidines and bisbenzimidazolines as noncompetitive NMDA receptor antagonists", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS , 9(9), 1299-1304 CODEN: BMCLE8; ISSN: 0960-894X, 1999, XP004163962 *

Also Published As

Publication number Publication date
WO2006016237A2 (fr) 2006-02-16

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