WO2006084643A3 - Nouveau gene rcs 26 - Google Patents

Nouveau gene rcs 26 Download PDF

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Publication number
WO2006084643A3
WO2006084643A3 PCT/EP2006/001009 EP2006001009W WO2006084643A3 WO 2006084643 A3 WO2006084643 A3 WO 2006084643A3 EP 2006001009 W EP2006001009 W EP 2006001009W WO 2006084643 A3 WO2006084643 A3 WO 2006084643A3
Authority
WO
WIPO (PCT)
Prior art keywords
polynucleotides
production
vitamin
relates
microorganisms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2006/001009
Other languages
English (en)
Other versions
WO2006084643A2 (fr
Inventor
Masako Shinjoh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DSM IP Assets BV
Original Assignee
DSM IP Assets BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DSM IP Assets BV filed Critical DSM IP Assets BV
Publication of WO2006084643A2 publication Critical patent/WO2006084643A2/fr
Publication of WO2006084643A3 publication Critical patent/WO2006084643A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/04—Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La présente invention concerne des micro-organismes récemment identifiés qui sont capables de produire directement de l'acide L-ascorbique (également appelé vitamine C ci-après). L'invention concerne aussi des séquences polynucléotidiques comprenant des gènes qui codent pour des protéines impliquées dans la synthèse de la vitamine C. L'invention concerne également des polynucléotides comprenant les séquences polynucléotidiques pleine longueur des nouveaux gènes et de leurs fragments, les nouveaux polypeptides codés par ces polynucléotides et leurs fragments, ainsi que leurs équivalents fonctionnels. De plus, la présente invention porte sur l'utilisation desdits polynucléotides et polypeptides en tant qu'outils biologiques pour la production de vitamine C à partir de micro-organismes, la modification desdits polynucléotides et/ou polypeptides codés ayant une incidence directe ou indirecte sur le rendement, la production et/ou l'efficacité de la production du produit de fermentation dans ledit micro-organisme. Sont également décrits des procédés/processus d'utilisation des polynucléotides et séquences polynucléotidiques modifiées pour la transformation de micro-organismes hôtes. Enfin, l'invention concerne des micro-organismes génétiquement modifiés et leur utilisation pour la production directe de vitamine C.
PCT/EP2006/001009 2005-02-11 2006-02-06 Nouveau gene rcs 26 Ceased WO2006084643A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05405098 2005-02-11
EP05405098.4 2005-02-11

Publications (2)

Publication Number Publication Date
WO2006084643A2 WO2006084643A2 (fr) 2006-08-17
WO2006084643A3 true WO2006084643A3 (fr) 2006-11-02

Family

ID=36644264

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2006/001009 Ceased WO2006084643A2 (fr) 2005-02-11 2006-02-06 Nouveau gene rcs 26

Country Status (1)

Country Link
WO (1) WO2006084643A2 (fr)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0832974A2 (fr) * 1996-09-19 1998-04-01 F. Hoffmann-La Roche Ag Déshydrogénase d'alcool et d'aldéhyde
WO2004029268A1 (fr) * 2002-09-27 2004-04-08 Dsm Ip Assets B.V. Production microbienne de vitamine c
WO2005017159A2 (fr) * 2003-08-14 2005-02-24 Dsm Ip Assets B.V. Production microbienne d'acide l-ascorbique

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0832974A2 (fr) * 1996-09-19 1998-04-01 F. Hoffmann-La Roche Ag Déshydrogénase d'alcool et d'aldéhyde
WO2004029268A1 (fr) * 2002-09-27 2004-04-08 Dsm Ip Assets B.V. Production microbienne de vitamine c
WO2005017159A2 (fr) * 2003-08-14 2005-02-24 Dsm Ip Assets B.V. Production microbienne d'acide l-ascorbique

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
BREMUS ET AL: "The use of microorganisms in l-ascorbic acid production", JOURNAL OF BIOTECHNOLOGY, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 124, no. 1, 25 June 2006 (2006-06-25), pages 196 - 205, XP005480510, ISSN: 0168-1656 *
DATABASE EMBL EBI; 24 January 2005 (2005-01-24), XP002390336, retrieved from EBI accession no. CP000009 *
DATABASE UniProt 19 September 2002 (2002-09-19), XP002390337, retrieved from EBI Database accession no. Q8XZJ6 *
HANCOCK R D ET AL: "Biotechnological approaches for l-ascorbic acid production", TRENDS IN BIOTECHNOLOGY, ELSEVIER PUBLICATIONS, CAMBRIDGE, GB, vol. 20, no. 7, 1 July 2002 (2002-07-01), pages 299 - 305, XP004361398, ISSN: 0167-7799 *
MACAULEY S ET AL: "THE GENUS GLUCONOBACTER AND ITS APPLICATIONS IN BIOTECHNOLOGY", CRC CRITICAL REVIEWS IN BIOTECHNOLOGY, CRC PRESS, BOCA RATON, FL, US, vol. 21, no. 1, 2001, pages 1 - 25, XP008026977, ISSN: 0738-8551 *
PRUST C ET AL: "Complete genome sequence of the acetic acid bacterium Gluconobacter oxydans", NATURE BIOTECHNOLOGY, NATURE PUBLISHING GROUP, NEW YORK, NY, US, vol. 23, no. 2, February 2005 (2005-02-01), pages 195 - 200, XP002334906, ISSN: 1087-0156 *
SUGISAWA T ET AL: "MICROBIAL PRODUCTION OF L-ASCORBIC ACID FROM D-SORBITOL, L-SORBOSE, L-GULOSE, AND L-SORBOSONE BY KETOGULONICIGENIUM VULGARE DSM 4025", BIOSCIENCE BIOTECHNOLOGY BIOCHEMISTRY, JAPAN SOC. FOR BIOSCIENCE, BIOTECHNOLOGY AND AGROCHEM, TOKYO, JP, vol. 69, no. 3, 2005, pages 659 - 662, XP009054184, ISSN: 0916-8451 *

Also Published As

Publication number Publication date
WO2006084643A2 (fr) 2006-08-17

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