WO2006117404A3 - Topische verwendung von radikalfangenden substanzen zur antipyretischen behandlung - Google Patents

Topische verwendung von radikalfangenden substanzen zur antipyretischen behandlung Download PDF

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Publication number
WO2006117404A3
WO2006117404A3 PCT/EP2006/062075 EP2006062075W WO2006117404A3 WO 2006117404 A3 WO2006117404 A3 WO 2006117404A3 EP 2006062075 W EP2006062075 W EP 2006062075W WO 2006117404 A3 WO2006117404 A3 WO 2006117404A3
Authority
WO
WIPO (PCT)
Prior art keywords
radical capturing
preparation
substances
capturing substances
topical use
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2006/062075
Other languages
English (en)
French (fr)
Other versions
WO2006117404A2 (de
Inventor
Karin Golz-Berner
Leonhard Zastrow
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Coty Prestige Lancaster Group GmbH
Original Assignee
Coty Prestige Lancaster Group GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Coty Prestige Lancaster Group GmbH filed Critical Coty Prestige Lancaster Group GmbH
Priority to EP06755030A priority Critical patent/EP1877046A2/de
Priority to US11/913,488 priority patent/US20090081285A1/en
Priority to JP2008509456A priority patent/JP2008540386A/ja
Publication of WO2006117404A2 publication Critical patent/WO2006117404A2/de
Publication of WO2006117404A3 publication Critical patent/WO2006117404A3/de
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/203—Retinoic acids ; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/18—Antioxidants, e.g. antiradicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)

Abstract

Die vorliegende Erfindung betrifft die Verwendung von einer oder mehreren radikalfangenden Substanzen als therapeutisch wirksame Substanzen in einer topischen Zubereitung zur antipyretischen Behandlung. Gegenstand der Erfindung ist auch die Verwendung von radikalfangenden Substanzen als Wirkstoffe in einem Kombinationspräparat zur Behandlung von Fieber, wobei das Kombinationspräparat eine topische Zubereitung und eine orale Zubereitung in einer freien Kombination umfasst und beide Zubereitungen unabhängig voneinander eine oder mehrere freie Radikale fangende Substanzen beinhalten. Die beiden Zubereitungen des Kombinationspräparates sind erfindungsgemäß zur gleichzeitigen, getrennten oder zeitlich abgestuften Verabreichung vorgesehen.
PCT/EP2006/062075 2005-05-04 2006-05-04 Topische verwendung von radikalfangenden substanzen zur antipyretischen behandlung Ceased WO2006117404A2 (de)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP06755030A EP1877046A2 (de) 2005-05-04 2006-05-04 Topische verwendung von radikalfangenden substanzen zur antipyretischen behandlung
US11/913,488 US20090081285A1 (en) 2005-05-04 2006-05-04 Use of radical-capturing substances in a topical preparation for antipyretic treatment
JP2008509456A JP2008540386A (ja) 2005-05-04 2006-05-04 解熱治療のためのラジカル捕捉物質の局所使用

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102005021806A DE102005021806A1 (de) 2005-05-04 2005-05-04 Verwendung von radikalfangenden Substanzen zur Behandlung von Zuständen mit erhöhter Hauttemperatur, insbesondere zur antipyretischen Behandlung
DE102005021806.7 2005-05-04

Publications (2)

Publication Number Publication Date
WO2006117404A2 WO2006117404A2 (de) 2006-11-09
WO2006117404A3 true WO2006117404A3 (de) 2007-06-28

Family

ID=36649658

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2006/062075 Ceased WO2006117404A2 (de) 2005-05-04 2006-05-04 Topische verwendung von radikalfangenden substanzen zur antipyretischen behandlung

Country Status (5)

Country Link
US (1) US20090081285A1 (de)
EP (1) EP1877046A2 (de)
JP (1) JP2008540386A (de)
DE (1) DE102005021806A1 (de)
WO (1) WO2006117404A2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2905028B1 (fr) * 2006-08-21 2008-12-19 Commissariat Energie Atomique Dispositif de memoire electrochimique
WO2008058333A1 (en) 2006-11-15 2008-05-22 Arthritis Relief Plus Ltd Topical formulation and uses thereof
CA2792837A1 (en) * 2010-03-17 2011-09-22 Arbonne International Llc Oral supplement
CA2819383C (en) * 2010-05-28 2019-01-15 Nexgen Dermatologics, Inc. Compositions and methods for treating bruises
CN117757156A (zh) * 2023-12-06 2024-03-26 中北大学 基于自由基湮灭反应的强界面作用同时增强增韧的石墨烯改性天然橡胶

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4534980A (en) * 1984-04-03 1985-08-13 Hokuriku Pharmaceutical Co., Ltd. Antiinflammatory and antipyretic cream
FR2649322A1 (fr) * 1989-07-04 1991-01-11 Natura Medica Laboratoires Complexes biodisponibles d'acide (alpha)-linolenique, extraits de plantes en contenant et compositions pharmaceutiques les incorporant
WO1994002446A1 (en) * 1992-07-23 1994-02-03 British Biotech Pharmaceuticals Limited Natural amino acid derivatives as metalloproteinase inhibitors
WO1999066881A2 (de) * 1998-06-24 1999-12-29 Coty B.V. Kosmetische wirkstoffzubereitung mit hohem radikalschutzfaktor
WO2001026617A1 (de) * 1999-10-08 2001-04-19 Coty B.V. Kosmetische wirkstoffzubereitung mit synergistisch erhöhtem radikalschutzfaktor
WO2002009763A2 (en) * 2000-07-27 2002-02-07 Ben Gurion University Of The Negev Research And Development Authority Transdermal drug delivery system
WO2004105717A1 (de) * 2003-05-28 2004-12-09 Coty B.V. Kosmetikum mit mineralwasser für die remineralisierungs- und anti-alterungsbehandlung der haut
DE10325156A1 (de) * 2003-05-28 2004-12-23 Coty B.V. Wirkstoffzubereitung mit Pflanzenextrakten für Kosmetika

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4636516A (en) * 1981-02-19 1987-01-13 Yamanouchi Pharmaceutical Co., Ltd. 3,5-di-tert-butyl-4-hydroxyphenyl-substituted heterocyclic compounds
JP2004300107A (ja) * 2003-04-01 2004-10-28 Aikusu Lab Sangyo:Kk 経皮消炎鎮痛剤組成物

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4534980A (en) * 1984-04-03 1985-08-13 Hokuriku Pharmaceutical Co., Ltd. Antiinflammatory and antipyretic cream
FR2649322A1 (fr) * 1989-07-04 1991-01-11 Natura Medica Laboratoires Complexes biodisponibles d'acide (alpha)-linolenique, extraits de plantes en contenant et compositions pharmaceutiques les incorporant
WO1994002446A1 (en) * 1992-07-23 1994-02-03 British Biotech Pharmaceuticals Limited Natural amino acid derivatives as metalloproteinase inhibitors
WO1999066881A2 (de) * 1998-06-24 1999-12-29 Coty B.V. Kosmetische wirkstoffzubereitung mit hohem radikalschutzfaktor
WO2001026617A1 (de) * 1999-10-08 2001-04-19 Coty B.V. Kosmetische wirkstoffzubereitung mit synergistisch erhöhtem radikalschutzfaktor
WO2002009763A2 (en) * 2000-07-27 2002-02-07 Ben Gurion University Of The Negev Research And Development Authority Transdermal drug delivery system
WO2004105717A1 (de) * 2003-05-28 2004-12-09 Coty B.V. Kosmetikum mit mineralwasser für die remineralisierungs- und anti-alterungsbehandlung der haut
DE10325156A1 (de) * 2003-05-28 2004-12-23 Coty B.V. Wirkstoffzubereitung mit Pflanzenextrakten für Kosmetika

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
ASANUMA MASATO ET AL: "Neuroprotective effects of non-steroidal anti-inflammatory drugs by direct scavenging of nitric oxide radicals", JOURNAL OF NEUROCHEMISTRY, vol. 76, no. 6, March 2001 (2001-03-01), pages 1895 - 1904, XP008074336, ISSN: 0022-3042 *
DINIS TERESA C P ET AL: "Action of phenolic derivatives (acetaminophen, salicylate, and 5-aminosalicylate) as inhibitors of membrane lipid peroxidation and as peroxyl radical scavengers", ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, vol. 315, no. 1, 1994, pages 161 - 169, XP008074377, ISSN: 0003-9861 *
HERBORT C P ET AL: "Usefulness of the Laser Flare Cell Meter (LFCM, Kowa FC-1000) in clinical practice", KLINISCHE MONATSBLATTER FUR AUGENHEILKUNDE 1991 GERMANY, vol. 198, no. 5, 1991, pages 470 - 473, XP008074431, ISSN: 0023-2165 *
HERBORT CARL P: "Uveoscleritis after excessive neodymium:YAG laser posterior capsulotomy", JOURNAL OF CATARACT AND REFRACTIVE SURGERY, vol. 20, no. 1, 1994, pages 80 - 81, XP008074425, ISSN: 0886-3350 *
TANG YOU-ZHI ET AL: "Evaluation of the free-radical-scavenging activity of diclofenac acid on the free-radical-induced haemolysis of human erythrocytes", JOURNAL OF PHARMACY AND PHARMACOLOGY, vol. 58, no. 5, May 2006 (2006-05-01), pages 625 - 631, XP008074378, ISSN: 0022-3573 *

Also Published As

Publication number Publication date
EP1877046A2 (de) 2008-01-16
DE102005021806A1 (de) 2006-11-16
US20090081285A1 (en) 2009-03-26
JP2008540386A (ja) 2008-11-20
WO2006117404A2 (de) 2006-11-09

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