WO2006131676A3 - Procede utile pour la detection d'encephalopathies - Google Patents

Procede utile pour la detection d'encephalopathies Download PDF

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Publication number
WO2006131676A3
WO2006131676A3 PCT/FR2006/050528 FR2006050528W WO2006131676A3 WO 2006131676 A3 WO2006131676 A3 WO 2006131676A3 FR 2006050528 W FR2006050528 W FR 2006050528W WO 2006131676 A3 WO2006131676 A3 WO 2006131676A3
Authority
WO
WIPO (PCT)
Prior art keywords
detecting
encephalopathies
concerns
prion
tsse
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/FR2006/050528
Other languages
English (en)
Other versions
WO2006131676A2 (fr
Inventor
Jean-Michel Verdier
Catherine Gregoire
Veronique Perrier-Rondard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut National de la Sante et de la Recherche Medicale INSERM
Original Assignee
Institut National de la Sante et de la Recherche Medicale INSERM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut National de la Sante et de la Recherche Medicale INSERM filed Critical Institut National de la Sante et de la Recherche Medicale INSERM
Priority to AU2006256643A priority Critical patent/AU2006256643A1/en
Priority to EP06764848A priority patent/EP1889074A2/fr
Priority to CN2006800247597A priority patent/CN101248355B/zh
Priority to CA002611206A priority patent/CA2611206A1/fr
Priority to US11/921,640 priority patent/US8435744B2/en
Priority to JP2008515265A priority patent/JP2008545775A/ja
Publication of WO2006131676A2 publication Critical patent/WO2006131676A2/fr
Publication of WO2006131676A3 publication Critical patent/WO2006131676A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G01N2800/2814—Dementia; Cognitive disorders
    • G01N2800/2828—Prion diseases

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

La présente invention concerne un procédé utile pour la détection d'une ESST ou maladie à prions. Elle vise en outre un procédé utile pour l'amplification de Foligomérisation des isoformes PrPSc du prion cellulaire.
PCT/FR2006/050528 2005-06-07 2006-06-07 Procede utile pour la detection d'encephalopathies Ceased WO2006131676A2 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
AU2006256643A AU2006256643A1 (en) 2005-06-07 2006-06-07 Method for detecting encephalopathies
EP06764848A EP1889074A2 (fr) 2005-06-07 2006-06-07 Procede utile pour la detection d'encephalopathies
CN2006800247597A CN101248355B (zh) 2005-06-07 2006-06-07 用于检测脑病的方法
CA002611206A CA2611206A1 (fr) 2005-06-07 2006-06-07 Detection d'encephalopathies par amplification de l'oligomerisation des prpsc
US11/921,640 US8435744B2 (en) 2005-06-07 2006-06-07 Method useful for detecting encephalopathies
JP2008515265A JP2008545775A (ja) 2005-06-07 2006-06-07 脳症を検出するために有用な方法

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05300463A EP1731911A1 (fr) 2005-06-07 2005-06-07 Procédé utile pour la détection d'encéphalopathies
EP05300463.6 2005-06-07

Publications (2)

Publication Number Publication Date
WO2006131676A2 WO2006131676A2 (fr) 2006-12-14
WO2006131676A3 true WO2006131676A3 (fr) 2007-02-01

Family

ID=35266963

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR2006/050528 Ceased WO2006131676A2 (fr) 2005-06-07 2006-06-07 Procede utile pour la detection d'encephalopathies

Country Status (7)

Country Link
US (1) US8435744B2 (fr)
EP (2) EP1731911A1 (fr)
JP (1) JP2008545775A (fr)
CN (1) CN101248355B (fr)
AU (1) AU2006256643A1 (fr)
CA (1) CA2611206A1 (fr)
WO (1) WO2006131676A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8835449B2 (en) 2011-11-11 2014-09-16 Pfizer Inc. 2-thiopyrimidinones

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1731911A1 (fr) * 2005-06-07 2006-12-13 Institut National De La Sante Et De La Recherche Medicale (Inserm) Procédé utile pour la détection d'encéphalopathies
EP2072511A1 (fr) * 2007-12-21 2009-06-24 INSERM (Institut National de la Santé et de la Recherche Médicale) Procédé utile pour amplifier, détecter et réduire les formes pathologiques de la protéine de prion cellulaire
FR2929290B1 (fr) * 2008-03-27 2010-05-07 Lfb Biotechnologies Methode de detection et/ou de titrage in vitro d'un agent transmissible non conventionnel
WO2011038204A1 (fr) 2009-09-25 2011-03-31 N30 Pharmaceuticals, Llc Nouveaux composés dihydropyrimidine-2(1h)-ones en tant qu'inhibiteurs de la s-nitrosoglutathion réductase
US8906933B2 (en) 2010-09-24 2014-12-09 N30 Pharmaceuticals, Inc. Dihydropyrimidin-2(1H)-one compounds as neurokinin-3 receptor antagonists
AU2016257179A1 (en) 2015-05-05 2017-11-02 Pfizer Inc. 2-thiopyrimidinones

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5142033A (en) * 1988-09-23 1992-08-25 Hoffmann-La Roche Inc. Structure-independent DNA amplification by the polymerase chain reaction
WO2002004954A2 (fr) * 2000-07-07 2002-01-17 Applied Research Systems Ars Holding N.V. Diagnostic precoce de maladies conformationelles
US20020012639A1 (en) * 1999-01-08 2002-01-31 Glenn Robert Wayne Topical compositions comprising protected functional thiols
WO2003087057A1 (fr) * 2002-04-05 2003-10-23 Astrazeneca Ab Derives de benzamide utiles en tant qu'inhibiteurs d'histone deacetylase
WO2003094904A1 (fr) * 2002-05-13 2003-11-20 Beth Israel Deaconess Medical Center Methodes et compositions de traitement du rejet de greffe
US20050049487A1 (en) * 2003-08-26 2005-03-03 Johnson Bruce Fletcher Compounds and kits for preparing imaging agents and methods of imaging
WO2005033102A2 (fr) * 2003-10-03 2005-04-14 Amphora Discovery Corporation Composes a base de thiophene presentant une activite d'inhibition d'enzymes utilisant l'atp, compositions contenant ces composes et utilisations

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2801106B1 (fr) 1999-11-12 2007-10-05 Commissariat Energie Atomique Procede de diagnostic d'une esst provoquee par une souche d'atnc dans un echantillon biologique et son utilisation dans le diagnostic differentiel des differentes souches d'atnc
US7563748B2 (en) 2003-06-23 2009-07-21 Cognis Ip Management Gmbh Alcohol alkoxylate carriers for pesticide active ingredients
EP1731911A1 (fr) * 2005-06-07 2006-12-13 Institut National De La Sante Et De La Recherche Medicale (Inserm) Procédé utile pour la détection d'encéphalopathies

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5142033A (en) * 1988-09-23 1992-08-25 Hoffmann-La Roche Inc. Structure-independent DNA amplification by the polymerase chain reaction
US20020012639A1 (en) * 1999-01-08 2002-01-31 Glenn Robert Wayne Topical compositions comprising protected functional thiols
WO2002004954A2 (fr) * 2000-07-07 2002-01-17 Applied Research Systems Ars Holding N.V. Diagnostic precoce de maladies conformationelles
WO2003087057A1 (fr) * 2002-04-05 2003-10-23 Astrazeneca Ab Derives de benzamide utiles en tant qu'inhibiteurs d'histone deacetylase
WO2003094904A1 (fr) * 2002-05-13 2003-11-20 Beth Israel Deaconess Medical Center Methodes et compositions de traitement du rejet de greffe
US20050049487A1 (en) * 2003-08-26 2005-03-03 Johnson Bruce Fletcher Compounds and kits for preparing imaging agents and methods of imaging
WO2005033102A2 (fr) * 2003-10-03 2005-04-14 Amphora Discovery Corporation Composes a base de thiophene presentant une activite d'inhibition d'enzymes utilisant l'atp, compositions contenant ces composes et utilisations

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ETESSAMI R ET AL: "Scratch-wounding renders cultivated cells less permissive to prion infection", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC., vol. 330, no. 1, 29 April 2005 (2005-04-29), ORLANDO, FL, US, pages 5 - 10, XP004801574, ISSN: 0006-291X *
WONG C ET AL: "Sulfated glycans and elevated temperature stimulate PrPSc-dependent cell-free formation of protease-resistant prion protein", EMBO JOURNAL, OXFORD UNIVERSITY PRESS, vol. 20, no. 3, 1 February 2001 (2001-02-01), SURREY, GB, pages 377 - 386, XP002258983, ISSN: 0261-4189 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8835449B2 (en) 2011-11-11 2014-09-16 Pfizer Inc. 2-thiopyrimidinones
US8841314B2 (en) 2011-11-11 2014-09-23 Pfizer Inc. 2-Thiopyrimidinones
US9399626B2 (en) 2011-11-11 2016-07-26 Pfizer Inc. 2-thiopyrimidinones

Also Published As

Publication number Publication date
EP1731911A1 (fr) 2006-12-13
JP2008545775A (ja) 2008-12-18
AU2006256643A8 (en) 2008-04-17
US20090130689A1 (en) 2009-05-21
CN101248355A (zh) 2008-08-20
CN101248355B (zh) 2013-06-12
CA2611206A1 (fr) 2006-12-14
US8435744B2 (en) 2013-05-07
WO2006131676A2 (fr) 2006-12-14
AU2006256643A1 (en) 2006-12-14
EP1889074A2 (fr) 2008-02-20

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