WO2007120263A3 - Préparation de dutastéride - Google Patents

Préparation de dutastéride Download PDF

Info

Publication number
WO2007120263A3
WO2007120263A3 PCT/US2006/060767 US2006060767W WO2007120263A3 WO 2007120263 A3 WO2007120263 A3 WO 2007120263A3 US 2006060767 W US2006060767 W US 2006060767W WO 2007120263 A3 WO2007120263 A3 WO 2007120263A3
Authority
WO
WIPO (PCT)
Prior art keywords
dutasteride
preparation
dihydrodutasteride
desmethyldutasteride
purifying
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2006/060767
Other languages
English (en)
Other versions
WO2007120263A2 (fr
Inventor
Srinivas Katkam
Satyanarayana Komati
Srinivasulu Gudipati
Jayaprakash Pitta
Nageswara Rao Challa
Ravinder Bucchikondla
Srinivasa Rao Mallina
Adolf Ceaser Goldwyn
Manoj Ramesh Kharkar
Sharat Pandurang Narsapur
Srinivasula Reddy Maddula
Ramamurthy Kasula
Arvind Mallinath Lali
Sandeep Bhaskar Kale
Abijar Joyebbhai Bhori
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dr Reddys Laboratories Ltd
Dr Reddys Laboratories Inc
Original Assignee
Dr Reddys Laboratories Ltd
Dr Reddys Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Reddys Laboratories Ltd, Dr Reddys Laboratories Inc filed Critical Dr Reddys Laboratories Ltd
Priority to EP06850136A priority Critical patent/EP1945615A2/fr
Publication of WO2007120263A2 publication Critical patent/WO2007120263A2/fr
Publication of WO2007120263A3 publication Critical patent/WO2007120263A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/18—Ring systems of four or more rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La présente invention concerne du dutastéride avec de faibles concentrations d'impuretés, tels que du dihydrodutastéride et du desméthyldutastéride, ainsi que des procédés de purification du dutastéride.
PCT/US2006/060767 2005-11-10 2006-11-10 Préparation de dutastéride Ceased WO2007120263A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP06850136A EP1945615A2 (fr) 2005-11-10 2006-11-10 Préparation de dutastéride

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US73526605P 2005-11-10 2005-11-10
US60/735,266 2005-11-10
IN1655/CHE/2005 2005-11-14
IN1655CH2005 2005-11-14
US74586406P 2006-04-28 2006-04-28
US60/745,864 2006-04-28
US74621106P 2006-05-02 2006-05-02
US60/746,211 2006-05-02

Publications (2)

Publication Number Publication Date
WO2007120263A2 WO2007120263A2 (fr) 2007-10-25
WO2007120263A3 true WO2007120263A3 (fr) 2007-12-21

Family

ID=38609977

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/060767 Ceased WO2007120263A2 (fr) 2005-11-10 2006-11-10 Préparation de dutastéride

Country Status (2)

Country Link
EP (1) EP1945615A2 (fr)
WO (1) WO2007120263A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103044517A (zh) * 2012-12-05 2013-04-17 华润赛科药业有限责任公司 五种度他雄胺杂质的制备方法

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR070313A1 (es) * 2008-01-03 2010-03-31 Gador Sa Un procedimiento para preparar una forma solida y cristalina de dutasteride, una forma polimorfica del compuesto (forma iii) y una composicion farmaceutica que incluye dicha forma
EP2468262A1 (fr) 2010-12-06 2012-06-27 Krka Tovarna Zdravil, D.D., Novo Mesto Composition pharmaceutique contenant de la dutastéride
CN102863507A (zh) * 2012-09-29 2013-01-09 华润赛科药业有限责任公司 一种度他雄胺的精制方法
CN103724397B (zh) * 2012-10-15 2015-10-21 齐鲁制药有限公司 一种度他雄胺晶型i的制备方法
WO2019107859A1 (fr) * 2017-11-28 2019-06-06 (주)아이엠디팜 Corps poreux nano-solubilisé encapsulant du dutastéride, composition pharmaceutique le contenant et son procédé de fabrication
CN114113363B (zh) * 2021-10-25 2024-06-11 人福普克药业（武汉）有限公司 一种度他雄胺软胶囊中杂质的检测方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5565467A (en) * 1993-09-17 1996-10-15 Glaxo Wellcome Inc. Androstenone derivative
US7022854B2 (en) * 2003-07-17 2006-04-04 Dr. Reddy's Laboratories, Limited Forms of dutasteride and methods for preparation thereof
US7038050B2 (en) * 2003-07-19 2006-05-02 Hanmi Pharm. Co., Ltd. Method for the preparation of highly pure 1-androstene derivatives

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5565467A (en) * 1993-09-17 1996-10-15 Glaxo Wellcome Inc. Androstenone derivative
US7022854B2 (en) * 2003-07-17 2006-04-04 Dr. Reddy's Laboratories, Limited Forms of dutasteride and methods for preparation thereof
US7038050B2 (en) * 2003-07-19 2006-05-02 Hanmi Pharm. Co., Ltd. Method for the preparation of highly pure 1-androstene derivatives

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103044517A (zh) * 2012-12-05 2013-04-17 华润赛科药业有限责任公司 五种度他雄胺杂质的制备方法

Also Published As

Publication number Publication date
EP1945615A2 (fr) 2008-07-23
WO2007120263A2 (fr) 2007-10-25

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