WO2007126834A3 - Polyéthylène glycol fonctionnalisé - Google Patents

Polyéthylène glycol fonctionnalisé Download PDF

Info

Publication number
WO2007126834A3
WO2007126834A3 PCT/US2007/007598 US2007007598W WO2007126834A3 WO 2007126834 A3 WO2007126834 A3 WO 2007126834A3 US 2007007598 W US2007007598 W US 2007007598W WO 2007126834 A3 WO2007126834 A3 WO 2007126834A3
Authority
WO
WIPO (PCT)
Prior art keywords
formula
ethylene glycol
functionalized poly
linking material
linking
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2007/007598
Other languages
English (en)
Other versions
WO2007126834A2 (fr
Inventor
John William Harder
Jeffrey Wade Leon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Carestream Health Inc
Original Assignee
Carestream Health Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Carestream Health Inc filed Critical Carestream Health Inc
Priority to EP07754161A priority Critical patent/EP2004723A2/fr
Publication of WO2007126834A2 publication Critical patent/WO2007126834A2/fr
Publication of WO2007126834A3 publication Critical patent/WO2007126834A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • C08G65/329—Polymers modified by chemical after-treatment with organic compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • C08G65/329—Polymers modified by chemical after-treatment with organic compounds
    • C08G65/334—Polymers modified by chemical after-treatment with organic compounds containing sulfur
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • C08G65/329—Polymers modified by chemical after-treatment with organic compounds
    • C08G65/334—Polymers modified by chemical after-treatment with organic compounds containing sulfur
    • C08G65/3344—Polymers modified by chemical after-treatment with organic compounds containing sulfur containing oxygen in addition to sulfur
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • C08G65/329—Polymers modified by chemical after-treatment with organic compounds
    • C08G65/334—Polymers modified by chemical after-treatment with organic compounds containing sulfur
    • C08G65/3348—Polymers modified by chemical after-treatment with organic compounds containing sulfur containing nitrogen in addition to sulfur

Landscapes

  • Chemical & Material Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Polyethers (AREA)
  • Medicinal Preparation (AREA)
  • Macromonomer-Based Addition Polymer (AREA)

Abstract

La présente invention concerne un composé bifonctionnel contenant un élément de liaison, une particule comprenant un élément de liaison, et un élément de liaison comprenant un squelette macromonomère de polyéthylène glycol qui porte un groupement polymérisable par voie radicalaire à l'une de ses extrémités et une fonction chimique réactive différente à l'autre extrémité, selon la Formule I : [insérer formule] Formule I où X représente CH3, CN ou H ; Y représente O, NR1 ou S ; L est un groupement de liaison ou un espaceur ; FG est un groupement fonctionnel ; n est supérieur à 4 et inférieur à 1000 ; et où R1 et R2 sont indépendamment sélectionnés parmi les groupements alkyle, aryle ou hétéroaryle éventuellement substitués.
PCT/US2007/007598 2006-04-10 2007-03-29 Polyéthylène glycol fonctionnalisé Ceased WO2007126834A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP07754161A EP2004723A2 (fr) 2006-04-10 2007-03-29 Polyéthylène glycol fonctionnalisé

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/400,935 US20070238656A1 (en) 2006-04-10 2006-04-10 Functionalized poly(ethylene glycol)
US11/400,935 2006-04-10

Publications (2)

Publication Number Publication Date
WO2007126834A2 WO2007126834A2 (fr) 2007-11-08
WO2007126834A3 true WO2007126834A3 (fr) 2007-12-13

Family

ID=38474231

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/007598 Ceased WO2007126834A2 (fr) 2006-04-10 2007-03-29 Polyéthylène glycol fonctionnalisé

Country Status (5)

Country Link
US (1) US20070238656A1 (fr)
EP (1) EP2004723A2 (fr)
CN (1) CN101421330A (fr)
TW (1) TW200808359A (fr)
WO (1) WO2007126834A2 (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100034748A1 (en) * 2008-08-07 2010-02-11 Guizhi Li Molecular imaging probes based on loaded reactive nano-scale latex
US20070237821A1 (en) * 2006-04-10 2007-10-11 Eastman Kodak Company Nanogel-based contrast agents for optical molecular imaging
US8203132B2 (en) 2005-09-08 2012-06-19 Carestream Health, Inc. Apparatus and method for imaging ionizing radiation
US8660631B2 (en) 2005-09-08 2014-02-25 Bruker Biospin Corporation Torsional support apparatus and method for craniocaudal rotation of animals
US20080181965A1 (en) * 2006-04-10 2008-07-31 Leon Jeffrey W Loaded latex optical molecular imaging probes
US8841134B2 (en) * 2006-04-10 2014-09-23 Bruker Biospin Corporation Fluorescence resonance energy transfer detection with nanoparticles for in vitro and in vivo applications
JP2011503517A (ja) 2006-11-13 2011-01-27 アテリス テクノロジーズ，エルエルシー 農薬バイオマーカー
US8906354B2 (en) 2007-02-28 2014-12-09 Bruker Biospin Corporation Loaded latex optical molecular imaging probes containing lipophilic large stokes shift dyes
US20100208348A1 (en) * 2008-08-22 2010-08-19 Carestream Health, Inc. Tunable spectral filtration device
CN102161754B (zh) * 2010-02-13 2012-06-13 华中科技大学同济医学院附属协和医院 枝化状聚乙二醇衍生物的功能化修饰方法
US8834846B2 (en) 2010-05-06 2014-09-16 Bruker Biospin Corporation Fluorescent NIRF activatable probes for disease detection
GB201008902D0 (en) 2010-05-27 2010-07-14 Imp Innovations Ltd Membrane enhanced polymer sythesis
US20140220346A1 (en) * 2012-12-04 2014-08-07 Memorial Sloan-Kettering Cancer Center Modular polymer hydrogel nanoparticles and methods of their manufacture
CN103342815B (zh) * 2013-06-24 2016-01-27 中国科学院深圳先进技术研究院 一种双马来酰亚胺-氰酸酯复合物、封装基板材料及其制备方法
EP3131534A4 (fr) 2014-04-17 2017-12-20 Memorial Sloan Kettering Cancer Center Nanogels à base de fucoidan et leurs procédés d'utilisation et de fabrication

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09255690A (ja) * 1996-01-16 1997-09-30 Mitsubishi Rayon Co Ltd 新規シラン化合物及びその製法、並びにその加水分解物で処理した無機微粒子
US20050176896A1 (en) * 1997-11-06 2005-08-11 Bentley Michael D. Heterobifunctional poly (ethylene glycol) derivatives and methods for their preparation

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4179337A (en) * 1973-07-20 1979-12-18 Davis Frank F Non-immunogenic polypeptides
US4002531A (en) * 1976-01-22 1977-01-11 Pierce Chemical Company Modifying enzymes with polyethylene glycol and product produced thereby
US4904584A (en) * 1987-12-23 1990-02-27 Genetics Institute, Inc. Site-specific homogeneous modification of polypeptides
US5298643A (en) * 1992-12-22 1994-03-29 Enzon, Inc. Aryl imidate activated polyalkylene oxides
US5349001A (en) * 1993-01-19 1994-09-20 Enzon, Inc. Cyclic imide thione activated polyalkylene oxides
US5321095A (en) * 1993-02-02 1994-06-14 Enzon, Inc. Azlactone activated polyalkylene oxides
US5756593A (en) * 1995-05-15 1998-05-26 Enzon, Inc. Method of preparing polyalkyene oxide carboxylic acids
EP0922446A1 (fr) * 1997-12-03 1999-06-16 Applied Research Systems Ars Holding N.V. Préparation des conjugués du GRF-PEG par un méthode en solution spécifique à un site
US7953788B2 (en) * 2001-09-29 2011-05-31 Siebel Systems, Inc. System and method for queuing data for an application server
DE69939036D1 (de) * 1998-04-28 2008-08-14 Serono Lab PEG Konjugate von LHRH Analogen
EE05214B1 (et) * 1998-04-28 2009-10-15 Applied Research Systems ARS Holding N.V. Polool-IFN- β konjugaat, selle valmistamismeetod ja farmatseutiline kompositsioon
US6958212B1 (en) * 1999-02-01 2005-10-25 Eidgenossische Technische Hochschule Zurich Conjugate addition reactions for the controlled delivery of pharmaceutically active compounds
US7291673B2 (en) * 2000-06-02 2007-11-06 Eidgenossiche Technische Hochschule Zurich Conjugate addition reactions for the controlled delivery of pharmaceutically active compounds
US20060239986A1 (en) * 2005-01-26 2006-10-26 Perez-Luna Victor H Method for the formation of hydrogel multilayers through surface initiated photopolymerization
US20070237821A1 (en) * 2006-04-10 2007-10-11 Eastman Kodak Company Nanogel-based contrast agents for optical molecular imaging
US20080181965A1 (en) * 2006-04-10 2008-07-31 Leon Jeffrey W Loaded latex optical molecular imaging probes

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09255690A (ja) * 1996-01-16 1997-09-30 Mitsubishi Rayon Co Ltd 新規シラン化合物及びその製法、並びにその加水分解物で処理した無機微粒子
US20050176896A1 (en) * 1997-11-06 2005-08-11 Bentley Michael D. Heterobifunctional poly (ethylene glycol) derivatives and methods for their preparation

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Week 199749, Derwent World Patents Index; AN 1997-532768, XP002451273 *
HARRIS J M: "LABORATORY SYNTHESIS OF POLYETHYLENE GLYCOL DERIVATIVES", JOURNAL OF MACROMOLECULAR SCIENCE-REVIEWS IN MACROMOLECULAR CHEMISTRY, MARCEL DEKKER JOURNALS. NEW YORK, US, vol. C-25, no. 3, 1985, pages 325 - 373, XP002036446, ISSN: 0736-6574 *
HERMAN S ET AL: "POLY(ETHYLENE GLYCOL) WITH REACTIVE ENDGROUPS: I. MODIFICATION OF PROTEINS", JOURNAL OF BIOACTIVE AND COMPATIBLE POLYMERS, LANCASTER, PA, US, vol. 10, no. 2, April 1995 (1995-04-01), pages 145 - 187, XP009032001 *

Also Published As

Publication number Publication date
WO2007126834A2 (fr) 2007-11-08
US20070238656A1 (en) 2007-10-11
EP2004723A2 (fr) 2008-12-24
TW200808359A (en) 2008-02-16
CN101421330A (zh) 2009-04-29

Similar Documents

Publication Publication Date Title
WO2007126834A3 (fr) Polyéthylène glycol fonctionnalisé
CN102741347B (zh) 具有改进耐火性能的可固化组合物
JP5684820B2 (ja) 経時的変性相を備える水分硬化組成物
WO2008008077A3 (fr) Polymères de polysiloxane fonctionnalisés
WO2008146685A1 (fr) Composé uréthane réactif ayant une liaison éther, composition durcissable et produit durci
WO2001049774A3 (fr) Compositions d'organosiloxane
WO2008081996A3 (fr) Composition à pigment dispersé, composition durcissable, filtre coloré, et procédé de production correspondant
WO2008117803A1 (fr) Composition de dispersion de pigment, composition photodurcissable, filtre coloré, et procédé de production du filtre coloré
WO2009011329A1 (fr) Composition durcissable
WO2008099858A1 (fr) Composition vulcanisable
CN102219439A (zh) 在矿物基底中半清洁和/或潮湿的钻孔表面上具有改善的粘附性的化学双组分砂浆组合物及其应用
CA2745307A1 (fr) Polyesters presentant des zwitterions greffes
EP0890594A4 (fr) Compositions de resine, dans un seul conditionnement et durcissant a froid par l'effet de l'humidite
WO2008123552A1 (fr) Matériau adhésif, feuille adhésive et utilisation de ladite feuille adhésive
JP2008540747A5 (fr)
TW200615286A (en) Activated energy radiation curable resin composition, process for preparing thereof and coating composition using the same
WO2009016848A1 (fr) Composition contenant un silsesquioxane et composition de résine d'hydroxyalkylcellulose contenant un silsesquioxane
WO2005042601A3 (fr) Polyether-urethanes durcissables a l'humidite pourvus de groupes silane reactifs et leur utilisation en tant que produits d'etancheite, adhesifs et revetements
JP2014504673A (ja) 組み合わせた安定剤を含んでなる硬化性組成物
WO2004009135A3 (fr) Nouveaux composes anticancereux
US5919867A (en) Block copolymer and a preparation process thereof
WO2001087998A3 (fr) Polymeres et melanges d'alkylacrylamides polymeriques antimicrobiens
TR200003237A2 (tr) İyileştirilebilir bileşim.
FI85587C (fi) Foerfarande foer modifiering av olefinpolymerer till sammankopplingsmedel.
ATE228524T1 (de) Modifizierte isocyanate mit tensideigenschaften, diese enthaltende zusammensetzungen und daraus hergestellte beschichtungen

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 07754161

Country of ref document: EP

Kind code of ref document: A2

WWE Wipo information: entry into national phase

Ref document number: 2007754161

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 200780012656.3

Country of ref document: CN

NENP Non-entry into the national phase

Ref country code: DE