WO2007138198A3 - Procede d'extraction d'une ou de plusieurs proteines presentes dans du lait - Google Patents

Procede d'extraction d'une ou de plusieurs proteines presentes dans du lait Download PDF

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Publication number
WO2007138198A3
WO2007138198A3 PCT/FR2007/000908 FR2007000908W WO2007138198A3 WO 2007138198 A3 WO2007138198 A3 WO 2007138198A3 FR 2007000908 W FR2007000908 W FR 2007000908W WO 2007138198 A3 WO2007138198 A3 WO 2007138198A3
Authority
WO
WIPO (PCT)
Prior art keywords
protein
milk
phase
lipid
extraction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/FR2007/000908
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English (en)
Other versions
WO2007138198A2 (fr
Inventor
Alain Lejars
Michel Nogre
Michel Tellier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LFB Biotechnologies SAS
Original Assignee
LFB Biotechnologies SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to CN200780020173.8A priority Critical patent/CN101501059B/zh
Application filed by LFB Biotechnologies SAS filed Critical LFB Biotechnologies SAS
Priority to KR1020147034304A priority patent/KR101593494B1/ko
Priority to BRPI0712005-2A priority patent/BRPI0712005A2/pt
Priority to EP07788820A priority patent/EP2038296A2/fr
Priority to AU2007266951A priority patent/AU2007266951C1/en
Priority to US12/300,495 priority patent/US20100047428A1/en
Priority to CA2652495A priority patent/CA2652495C/fr
Priority to JP2009512640A priority patent/JP5279087B2/ja
Publication of WO2007138198A2 publication Critical patent/WO2007138198A2/fr
Priority to IL195183A priority patent/IL195183A0/en
Anticipated expiration legal-status Critical
Publication of WO2007138198A3 publication Critical patent/WO2007138198A3/fr
Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/30—Extraction; Separation; Purification by precipitation
    • C07K1/303—Extraction; Separation; Purification by precipitation by salting out
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/644—Coagulation factor IXa (3.4.21.22)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21022—Coagulation factor IXa (3.4.21.22)

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Plant Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention concerne un procédé d'extraction d'au moins une protéine présente dans du lait, ladite protéine présentant une affinité pour les ions calcium complexés ou non dudit lait, comprenant les étapes suivantes consistant à : a) libérer la protéine par la précipitation de composés de calcium obtenue par mise en contact du lait avec un sel soluble, dont l'anion est choisi pour son aptitude à former dans un tel milieu lesdits composés de calcium insolubles, pour ainsi obtenir une phase liquide enrichie en la protéine, b) séparer la phase liquide enrichie en la protéine du précipité de composés de calcium, ladite phase liquide étant en outre séparée en une phase lipidique et en une phase aqueuse non lipidique comprenant la protéine, et c) récupérer la phase aqueuse non lipidique comprenant la protéine.
PCT/FR2007/000908 2006-05-31 2007-05-31 Procede d'extraction d'une ou de plusieurs proteines presentes dans du lait Ceased WO2007138198A2 (fr)

Priority Applications (9)

Application Number Priority Date Filing Date Title
JP2009512640A JP5279087B2 (ja) 2006-05-31 2007-05-31 母乳中に存在する１つ又は複数のタンパク質を抽出する方法
KR1020147034304A KR101593494B1 (ko) 2006-05-31 2007-05-31 우유에 존재하는 하나 이상의 단백질을 추출하는 방법
BRPI0712005-2A BRPI0712005A2 (pt) 2006-05-31 2007-05-31 método de extração de uma ou várias proteìnas no leite
EP07788820A EP2038296A2 (fr) 2006-05-31 2007-05-31 Procede d'extraction d'une ou de plusieurs proteines presentes dans du lait
AU2007266951A AU2007266951C1 (en) 2006-05-31 2007-05-31 Method for the extraction of one or several proteins present in milk
CN200780020173.8A CN101501059B (zh) 2006-05-31 2007-05-31 奶中一种或多种蛋白的提取方法
CA2652495A CA2652495C (fr) 2006-05-31 2007-05-31 Procede d'extraction d'une ou de plusieurs proteines presentes dans du lait
US12/300,495 US20100047428A1 (en) 2006-05-31 2007-05-31 Method for the extraction of one or several proteins in milk
IL195183A IL195183A0 (en) 2006-05-31 2008-11-09 Method for the extraction of one or several proteins present in milk

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0604864 2006-05-31
FR0604864A FR2901796A1 (fr) 2006-05-31 2006-05-31 Procede d'extraction d'une ou de plusieurs proteines presentes dans du lait

Publications (2)

Publication Number Publication Date
WO2007138198A2 WO2007138198A2 (fr) 2007-12-06
WO2007138198A3 true WO2007138198A3 (fr) 2009-04-23

Family

ID=37441903

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR2007/000908 Ceased WO2007138198A2 (fr) 2006-05-31 2007-05-31 Procede d'extraction d'une ou de plusieurs proteines presentes dans du lait

Country Status (13)

Country Link
US (1) US20100047428A1 (fr)
EP (1) EP2038296A2 (fr)
JP (2) JP5279087B2 (fr)
KR (2) KR101579811B1 (fr)
CN (2) CN103910779A (fr)
AR (2) AR061429A1 (fr)
AU (1) AU2007266951C1 (fr)
BR (1) BRPI0712005A2 (fr)
CA (1) CA2652495C (fr)
FR (1) FR2901796A1 (fr)
IL (1) IL195183A0 (fr)
TW (1) TWI394534B (fr)
WO (1) WO2007138198A2 (fr)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1711513B1 (fr) 2003-12-01 2014-07-02 Novo Nordisk Health Care AG Nanofiltration de compositions liquides contenant le facteur vii pour eliminer des virus
FR2901707B1 (fr) 2006-05-31 2017-09-29 Lab Francais Du Fractionnement Composition de facteur vii recombinant ou transgenique, chaque molecule de facteur vii possedant deux sites de n-glycosylation a motifs glycanniques definis
WO2011037957A2 (fr) * 2009-09-24 2011-03-31 U.S. Foods & Pharmaceuticals, Inc. Compositions et procédés pour réparation, maintenance et régénération osseuse
MX336728B (es) 2010-04-29 2016-01-27 Baxter Int Metodo de purificacion para proteinas de union de cation divalente en resina de intercambio anionico.
CN101885755B (zh) * 2010-06-09 2012-07-04 中国热带农业科学院热带生物技术研究所 一种巴西橡胶胶乳蛋白的提取方法
CN102127164B (zh) 2010-12-20 2013-01-30 武汉禾元生物科技有限公司 一种从水稻种子中提取重组人血清白蛋白的方法
CN102532254B (zh) 2010-12-24 2015-06-24 武汉禾元生物科技股份有限公司 一种从水稻种子中分离纯化重组人血清白蛋白的方法
KR20140054026A (ko) * 2011-07-07 2014-05-08 알에보 바이올로직스, 인코포레이티드 단백질을 안정화시키는 제제
JP6117219B2 (ja) 2011-10-14 2017-04-19 バクスアルタ ゲーエムベーハー 陰イオン交換クロマトグラフィによるタンパク質の精製方法
AU2012322948B2 (en) 2011-10-14 2014-11-06 Takeda Pharmaceutical Company Limited Protein purification by anion exchange chromatography
CN102746394A (zh) * 2012-01-05 2012-10-24 暨南大学 一种离子交换色谱分离乳源αs-酪蛋白的方法
AU2013202191A1 (en) * 2012-06-20 2014-01-16 Massey University Micronutrient Fortification Process and its Uses
EP2687595B1 (fr) 2012-07-19 2018-05-30 Laboratoire Français du Fractionnement et des Biotechnologies Procédé de purification de facteur VII transgénique
AU2013204850B2 (en) * 2012-10-08 2015-06-25 Murray Goulburn Co-Operative Co. Limited Improved process for purifying milk proteins and products thereof
AU2013204858B2 (en) * 2012-10-08 2015-06-25 Saputo Dairy Australia Pty Limited Improved process for purifying milk proteins and products thereof
CN103880947B (zh) 2012-12-21 2016-01-13 武汉禾元生物科技股份有限公司 一种分离纯化高纯度重组人血清白蛋白的层析方法
WO2014140289A1 (fr) 2013-03-15 2014-09-18 Baxter International Inc. Procédé de purification pour protéines dépendantes de la vitamine k par chromatographie d'échange d'anions
MX384222B (es) 2013-07-05 2025-03-14 Lab Francais Du Fractionnement Matriz de cromatografia de afinidad.
AT516149B1 (de) 2014-12-15 2016-03-15 MAN Truck & Bus Österreich AG Verfahren zum Steuern einer Motorbremsvorrichtung sowie Motorbremsvorrichtung
CN107373012B (zh) * 2017-08-15 2021-07-23 临邑禹王植物蛋白有限公司 一种大豆乳清蛋白的生产工艺
CN110623243B (zh) * 2019-09-11 2023-03-31 内蒙古蒙牛乳业（集团）股份有限公司 高钙盐类复合物及其制备方法
CN118909086B (zh) * 2024-10-12 2025-01-24 安徽天凯生物科技有限公司 一种分离α-乳白蛋白、β-乳球蛋白的方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6183803B1 (en) * 1999-06-11 2001-02-06 Biosante Pharmaceuticals, Inc. Method for processing milk
WO2001057079A2 (fr) * 2000-01-31 2001-08-09 Pharming Intellectual Property B.V. Inhibiteur de c1 produit dans du lait de mammiferes transgeniques
WO2004076695A1 (fr) * 2003-02-24 2004-09-10 Gtc Biotherapeutics, Inc. Procedes de filtration tangentielle et appareil associe

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3911143A (en) * 1970-08-20 1975-10-07 Foremost Mckesson Substitute product for nonfat dry milk and method for forming
FR2632524B1 (fr) * 1988-06-09 1992-03-13 Fondation Nale Transfusion San Procede de preparation d'une fraction concentree en facteur viia et son application a titre de medicament
US4988798A (en) * 1990-01-22 1991-01-29 Pitman-Moore, Inc. Method for recovering recombinant proteins
ATE209862T1 (de) * 1994-02-16 2001-12-15 Pharming Intellectual Pty Bv Isolierung von lactoferrin aus milch
WO1997035877A1 (fr) * 1996-03-25 1997-10-02 Haemopep Pharma Gmbh Peptides antibiotiques provenant du lait de bovin
CA2197515A1 (fr) * 1996-07-15 1998-01-16 Reyad Mahmoud Methodes pour traiter les produits laitiers
US7259243B2 (en) * 2000-01-07 2007-08-21 Arla Foods Amba Process for isolation of osteopontin from milk
JP4701472B2 (ja) * 2000-04-21 2011-06-15 雪印乳業株式会社 乳カルシウム組成物の製造方法
WO2002072024A2 (fr) * 2001-03-12 2002-09-19 Progenetics Llc Proteines transgeniques obtenues a partir de systemes multigeniques, procedes, compositions, utilisations et analogues apparentes
NZ511095A (en) * 2001-04-12 2003-06-30 New Zealand Dairy Board Subjecting a milk protein concentrate to cation exchange depleting the calcium content to produce a gel
GB0116509D0 (en) * 2001-07-06 2001-08-29 Hannah Res Inst The Methods of extracting casein fractions from milk and caseinates and production of novel products
WO2003013702A1 (fr) * 2001-08-06 2003-02-20 Gradipore Limited Separation de composants provenant de sources laitieres
US6806355B2 (en) * 2001-08-14 2004-10-19 Statens Serum Institut Purification process for large scale production of Gc-globulin, the Gc-globulin produced hereby, a use of Gc.globulin and a Gc-globulin medicinal product
CN1209030C (zh) * 2002-03-13 2005-07-06 赵伟洁 骨乳多肽酸奶活菌制剂及制备方法
US6911323B2 (en) * 2002-09-25 2005-06-28 Novo Nordisk Healthcare A/G Human coagulation factor VII polypeptides
AU2004220313B2 (en) * 2003-03-11 2011-06-02 Regen Therapeutics Plc Purification of peptides from colostrum
US20060194883A1 (en) * 2003-04-23 2006-08-31 Eisai Co., Ltd Mmp expression inhibitor
CN1493203A (zh) * 2003-09-05 2004-05-05 刘蒙榕 高含量免疫球蛋白乳猪初乳饲料
CN1606917A (zh) * 2003-10-13 2005-04-20 彭平 从牛奶中提取乳清蛋白及分离乳清蛋白中不同活性成分的方法
CN1557950A (zh) * 2004-02-04 2004-12-29 高春平 乳铁蛋白和乳过氧化物酶的制备方法
CN1260248C (zh) * 2004-09-03 2006-06-21 王秀英 从牦牛奶中提取的活性乳蛋白及其方法和应用
ES2349112T3 (es) * 2005-01-14 2010-12-28 Bayer Healthcare Llc Método de purificación de factor vii.

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6183803B1 (en) * 1999-06-11 2001-02-06 Biosante Pharmaceuticals, Inc. Method for processing milk
WO2001057079A2 (fr) * 2000-01-31 2001-08-09 Pharming Intellectual Property B.V. Inhibiteur de c1 produit dans du lait de mammiferes transgeniques
WO2004076695A1 (fr) * 2003-02-24 2004-09-10 Gtc Biotherapeutics, Inc. Procedes de filtration tangentielle et appareil associe

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
A S DAVE, D F BRULEY: "Separation of human protein C from components of transgenic milk using immobilized metal affinity chromatography", ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY, vol. 471, 2000, pages 639 - 647, XP008071126 *
WILKINS T D ET AL: "ISOLATION OF RECOMBINANT PROTEINS FROM MILK", JOURNAL OF CELLULAR BIOCHEMISTRY, LISS, NEW YORK, NY, US, vol. 49, no. 4, 1 August 1992 (1992-08-01), pages 333 - 338, XP000611844, ISSN: 0730-2312 *

Also Published As

Publication number Publication date
AR106315A2 (es) 2018-01-03
KR101579811B1 (ko) 2015-12-24
AU2007266951B2 (en) 2012-05-31
KR20090028694A (ko) 2009-03-19
IL195183A0 (en) 2011-08-01
CN101501059A (zh) 2009-08-05
JP2013163689A (ja) 2013-08-22
JP5279087B2 (ja) 2013-09-04
KR20150008455A (ko) 2015-01-22
EP2038296A2 (fr) 2009-03-25
TW200808188A (en) 2008-02-16
CN103910779A (zh) 2014-07-09
FR2901796A1 (fr) 2007-12-07
AU2007266951C1 (en) 2013-02-28
CA2652495C (fr) 2017-02-14
BRPI0712005A2 (pt) 2012-02-14
TWI394534B (zh) 2013-05-01
JP2009538884A (ja) 2009-11-12
CA2652495A1 (fr) 2007-12-06
KR101593494B1 (ko) 2016-02-15
AU2007266951A1 (en) 2007-12-06
AR061429A1 (es) 2008-08-27
CN101501059B (zh) 2014-05-14
WO2007138198A2 (fr) 2007-12-06
US20100047428A1 (en) 2010-02-25

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