WO2007138564A1 - Kit d'adaptation de lentille multiple - Google Patents

Kit d'adaptation de lentille multiple Download PDF

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Publication number
WO2007138564A1
WO2007138564A1 PCT/IL2006/000635 IL2006000635W WO2007138564A1 WO 2007138564 A1 WO2007138564 A1 WO 2007138564A1 IL 2006000635 W IL2006000635 W IL 2006000635W WO 2007138564 A1 WO2007138564 A1 WO 2007138564A1
Authority
WO
WIPO (PCT)
Prior art keywords
lens
lenses
haptic
assembly according
leverage
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IL2006/000635
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English (en)
Inventor
Henry M. Israel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Acuity Israel Ltd
Original Assignee
Acuity Israel Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acuity Israel Ltd filed Critical Acuity Israel Ltd
Priority to PCT/IL2006/000635 priority Critical patent/WO2007138564A1/fr
Publication of WO2007138564A1 publication Critical patent/WO2007138564A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/14Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A61F2/16Intraocular lenses
    • A61F2/1613Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/14Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A61F2/16Intraocular lenses
    • A61F2/1613Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
    • A61F2/1624Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus having adjustable focus; power activated variable focus means, e.g. mechanically or electrically by the ciliary muscle or from the outside
    • A61F2/1629Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus having adjustable focus; power activated variable focus means, e.g. mechanically or electrically by the ciliary muscle or from the outside for changing longitudinal position, i.e. along the visual axis when implanted
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/14Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A61F2/16Intraocular lenses
    • A61F2/1613Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
    • A61F2/1648Multipart lenses

Definitions

  • the present invention relates generally to intraocular lens (IOL) assemblies and particularly to accommodating IOL assemblies with multiple lenses.
  • Natural accommodation in a normal human eye having a normal human crystalline lens involves automatic contraction or constriction and relaxation of the ciliary muscle of the eye (and zonules controlled by the ciliary muscle) by the brain in response to looking at objects at different distances.
  • Ciliary muscle relaxation which is the normal state of the muscle, shapes the human crystalline lens for distant vision.
  • Ciliary muscle contraction shapes the human crystalline lens for near vision.
  • Accommodation The brain-induced change from distant vision to near vision is referred to as accommodation.
  • IOL intraocular lens
  • the IOL assembly includes at least two, preferably rigid, linkage arms, i.e., haptics, each being attached to the optic at a first position on the arm thereof and cooperating with ciliary muscle or the zonules at a second position on the arm. There are at least two pivots, one of which is rotatably attached to each respective haptic intermediate the first and second positions.
  • an accommodating IOL assembly is described in US Patent 6,524,340 to Israel, the disclosure of which is incorporated herein by reference.
  • the haptic does not apply leverage to the artificial lens.
  • one or more leverage arms which connect the haptic to the lens, apply the requisite lever force to the lens to impart accommodating motion to the lens.
  • the leverage arm applies a lever force along a chord inwards of the perimeter of the lens.
  • the leverage arm has a significantly greater "reach" and mechanical advantage than prior art accommodating IOLs, which rely on circumferentially attached haptics to apply leverage to the lens.
  • US Patent 6,767,363 to Bandhauer, et al. describes an accommodating intraocular lens system including a higher diopter positive intraocular lens and a lower diopter negative intraocular lens.
  • the positive intraocular lens includes a positive optic portion having an outer peripheral edge and two or more haptic elements.
  • the negative intraocular lens includes a negative optic portion having an outer peripheral edge and two or more haptic elements.
  • Each haptic element is formed to have specific flexibility characteristics so as to be less resistant to bending in a plane generally parallel to an eye's optical axis than in a plane generally perpendicular to the eye's optical axis.
  • the accommodating intraocular lens system is so designed with specific flexibility characteristics to facilitate axial displacement of the positive optic portion with respect to the negative optic portion along the eye's optical axis under a compression force.
  • Bandhauer et al. contemplates having the positive optic portion move anteriorly with respect to the negative optic portion, with the negative optic portion either remaining in place or moving posteriorly.
  • the present invention seeks to provide an improved accommodating IOL assembly in which lenses of a double or multiple lens IOL move anteriorly, as is described more in detail hereinbelow.
  • an intraocular lens assembly including a first lens and a second lens, a haptic, and a first leverage arm connecting the first lens to the haptic and a second leverage arm connecting the second lens to the haptic, the first and second lenses being arranged one in front of the other defining an anterior-posterior axis that passes perpendicularly through centers of the first and second lenses, wherein a width of the haptic extends beyond at least one of the first and second lenses in at least one direction parallel to the anterior-posterior axis.
  • the first leverage arm connects a perimeter of the first lens to the haptic and the second leverage arm connects a perimeter of the second lens to the haptic, wherein at least one of the first and second leverage arms is adapted to apply a lever force on its corresponding lens acting generally along a chord inwards of a perimeter of its corresponding lens.
  • the first lens may be a positive lens and the second lens may be a negative lens.
  • an intraocular lens assembly including a first lens and a second lens, a haptic, and a first leverage arm connecting the first lens to the haptic and a second leverage arm connecting the second lens to the haptic, the first and second lenses being arranged one in front of the other defining an anterior-posterior axis that passes perpendicularly through centers of the first and second lenses, wherein the first and second leverage arms are adapted to apply leverage to and move the first and second lenses along the anterior-posterior axis to achieve a combined positive diopter accommodative effect.
  • FIGs. 1, 2 and 3 are simplified pictorial, front view and rear view illustrations, respectively, of an intraocular lens (IOL) assembly, constructed and operative in accordance with an embodiment of the present invention
  • Fig. 4 A is a simplified side view illustration of the IOL assembly of Figs. 1-3, prior to anterior displacement of first and second lenses;
  • Fig. 4B is a simplified side view illustration of the IOL assembly of Figs. 1-3, in which the anterior movement of the first lens equals the anterior movement of the second lens;
  • Fig. 4C is a simplified side view illustration of the IOL assembly of Figs. 1-3, in which the anterior movement of the first lens does not equal the anterior movement of the second lens;
  • Fig. 4D is a simplified side view illustration of the IOL assembly of Figs. 1-3, in which a positive lens moves anteriorly and a negative lens moves posteriorly to give a total accommodative effect of a positive lens;
  • Fig. 4E is a simplified side view illustration of the IOL assembly of Figs. 1-3, in which a pair of negative lenses move posteriorly but still give a total accommodative effect of a positive lens.
  • FIG. 1-4 A illustrate an intraocular lens (IOL) assembly 10 constructed and operative in accordance with an embodiment of the present invention.
  • IOL intraocular lens
  • IOL assembly 10 may include a first lens 12 and a second lens 14, arranged one in front of the other defining an anterior-posterior axis 16 (Fig. 4A) that passes perpendicularly through centers of first and second lenses 12 and 14.
  • One or more first leverage arms 18 (in the illustrated embodiment a pair of first leverage arms 18 are employed) connect first lens 12 to a haptic 20.
  • one or more second leverage arms 22 (in the illustrated embodiment a pair of second leverage arms 22 are employed) connect second lens 14 to haptic 20.
  • two symmetric haptics 20 are employed, shaped generally like portions of a ring. It is understood that this is just one example of a suitably shaped haptic and other sizes and shapes of haptics may be used as well.
  • a width of haptic 20 preferably extends beyond at least one of first and second lenses 12 and 14 in at least one direction parallel to said anterior-posterior axis (this distance being indicated by letter "b").
  • Haptics are clearly defined in the art as the interface elements of the IOL that touch the eye structure ("haptic" is from the Greek word for touch).
  • the leverage arms 18 and 22 do not touch the eye structure and are not the haptics; rather they are attached to the haptics.
  • the attachment point of the leverage arm to the haptic may be flexible, or alternatively, may be rigid with other portions of the leverage arm being flexible.
  • IOL assembly 10 is preferably constructed of a clear, transparent, biologically compatible material, such as but not limited to, polymethylmethacrylate (PMMA), silicone, silicone rubber, collagen, hyaluronic acid (including the sodium, potassium and other salts thereof), hydrogel, such as acrylic or methacrylic hydrogels, e.g., hydroxyethyl methacrylate or methacrylic acid copolymer/partially hydrolyzed poly(2-hydroxyethyl methacrylate) (known as PoIyHEMA), polysulfones, thermolabile materials and other relatively hard or relatively soft and flexible biologically inert optical materials, or any combination of such materials, such as a gel encapsulated in a polymer.
  • IOL assembly 10 may thus be rigid, semi-rigid or foldable, for example.
  • First lens 12 may be a positive lens having a higher diopter positive optic portion, e.g., approximately +20 diopter or greater, such as but not limited to +20 to +60 diopter.
  • Second lens 14 may be a negative lens having a lower diopter negative optic portion, e.g., approximately -10 diopter or less, such as but not limited to -10 to -50 diopter.
  • the invention also encompasses the reverse, wherein the first lens 12 is a negative lens and the second lens 14 is a positive lens, as well both being positive lenses or both being negative lenses.
  • the number of diopters indicates the quantitative change in the distance between the lens and the focal point of light rays entering the lens.
  • a positive diopter value describes a convex lens, while a negative value describes a concave lens.
  • the focal point of light entering a convex lens is beyond the lens, while the focal point of light entering a concave lens is in front of the lens.
  • a positive (convex) lens collects light rays entering the eye and reduces the distance to the focal point.
  • a concave lens diverges light rays entering the eye, moving the true focal point of the light to a point in front of the lens.
  • First and second lenses 12 and 14 may be a combination of biconvex, plano-convex, plano-concave, biconcave, concave-convex (meniscus) or a diffractive-type lens of any shape, depending upon the power required to achieve the appropriate accommodative effects for multi-distance visual imaging and to achieve appropriate central and peripheral thickness for efficient handling and fit within an eye.
  • First and second lenses 12 and 14 may be monofocal or multi-focal lenses, and they may be spherical or aspherical. They may optionally comprise a graded index of refraction, holographic (diffusing) lenses, Fresnel lenses, diffracting lenses, and/or telescopic lenses, for example.
  • Leverage arms 18 and 22 may be configured generally as plates or beams or other shapes. Each pair of leverage arms may be attached to its corresponding lens at two attachment zones 24, which may be generally symmetric about the center of the lens. Each leverage arm may apply a lever force on its corresponding lens acting generally along a chord 26 inward of the perimeter of the lens 12 or 14. The chord 26 preferably connects the two attachment zones 24. Specifically, each leverage arm 18 or 22 acts as a torque or moment transfer device that transfers ciliary muscle relaxation or contraction (designated as distance e in Figs.
  • Each leverage arm 18 or 22 has a significantly greater "reach" and mechanical advantage than prior art accommodating IOLs, which rely on circumferentially attached haptics to apply leverage to the lens.
  • the force transferred by the leverage arms 18 and 22 is generally independent of the boundary condition of haptics 20.
  • both first and second lenses 12 and 14 are adapted to move anteriorly along the anterior-posterior axis 16 to achieve an accommodative effect.
  • This is in contrast to the prior art of US Patent 6,767,363 to Bandhauer, et al., wherein the positive optic portion moves anteriorly with respect to the negative optic portion, with the negative optic portion either remaining in place or moving posteriorly.
  • the present invention does contemplate having a positive lens move anteriorly and a negative lens move posteriorly or two negative lenses moving posteriorly, wherein in all cases the total effect is one of a positive lens, that is, reducing the distance to the focal point.
  • the haptics move the lenses without leverage.
  • leverage arms 18 and 22 apply leverage to and move the lenses 12 and 14, respectively. The combined sum of the lenses is positive in all locations within the accommodative motion.
  • Figs. 4B and 4C illustrate the anterior motion of the lenses.
  • the anterior movement of the first lens 12 is designated as (I 1 , whereas the anterior movement of the second lens 14 is designated as d 2 .
  • di d 2 , meaning that the distance between the first and second lenses 12 and 14 does not change as the lenses move anteriorly.
  • d ⁇ ⁇ d 2 meaning that the distance between the first and second lenses 12 and 14 changes as the lenses move anteriorly.
  • the difference influences the amount of diopters obtained in the accommodative effect.
  • Fig. 4D the front (positive) lens 12 moves anteriorly and the second (negative) lens 14 moves posteriorly.
  • the anterior movement of the first lens 12 is designated as g l5 whereas the posterior movement of the second lens 14 is designated as -g 2 .
  • Their motions contribute to a total accommodative effect of a positive lens, i.e., reduction of the distance to the focal point.
  • Fig. 4E the front (negative) lens 12 moves posteriorly and the second (negative) lens 14 also moves posteriorly.
  • the posterior movement of the first lens 12 is designated as -h 1 ⁇ whereas the posterior movement of the second lens 14 is designated as -g 2 .
  • Their motions contribute to a total accommodative effect of a positive lens, i.e., reduction of the distance to the focal point.
  • the leverage arms 18 and 22 may have different lengths. They may be attached at different points along peripheries of the first and second lenses 12 and 14, respectively. The different lengths and attachment points may be chosen to produce different effects, such as different anterior displacements, rotations of the lenses (e.g., about axis 16 or other axes) or lateral displacements of the lenses.

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  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Prostheses (AREA)

Abstract

L'invention concerne un kit de lentille intraoculaire comprenant une première lentille et une deuxième lentille, un élément haptique et un premier bras de levier reliant la première lentille à l'élément haptique et un second bras de levier reliant la deuxième lentille à l'élément haptique, la première et la deuxième lentilles étant disposées l'une en face de l'autre et définissant un axe antérieur-postérieur qui passe perpendiculairement à travers des centres de la première et de la deuxième lentilles, une largeur de l'élément haptique s'étendant au delà d'au moins une des première et deuxième lentilles dans au moins une direction parallèle à l'axe antérieur-postérieur.
PCT/IL2006/000635 2006-05-31 2006-05-31 Kit d'adaptation de lentille multiple Ceased WO2007138564A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/IL2006/000635 WO2007138564A1 (fr) 2006-05-31 2006-05-31 Kit d'adaptation de lentille multiple

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IL2006/000635 WO2007138564A1 (fr) 2006-05-31 2006-05-31 Kit d'adaptation de lentille multiple

Publications (1)

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WO2007138564A1 true WO2007138564A1 (fr) 2007-12-06

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Cited By (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010009257A1 (fr) * 2008-07-15 2010-01-21 Alcon, Inc. Lentille intraoculaire accommodative avec élément optique torique et profondeur de foyer étendue
US8314927B2 (en) 2007-07-23 2012-11-20 Powervision, Inc. Systems and methods for testing intraocular lenses
US8328869B2 (en) 2002-12-12 2012-12-11 Powervision, Inc. Accommodating intraocular lenses and methods of use
US8361145B2 (en) 2002-12-12 2013-01-29 Powervision, Inc. Accommodating intraocular lens system having circumferential haptic support and method
US8447086B2 (en) 2009-08-31 2013-05-21 Powervision, Inc. Lens capsule size estimation
US8668734B2 (en) 2010-07-09 2014-03-11 Powervision, Inc. Intraocular lens delivery devices and methods of use
US8900298B2 (en) 2010-02-23 2014-12-02 Powervision, Inc. Fluid for accommodating intraocular lenses
US8956408B2 (en) 2007-07-23 2015-02-17 Powervision, Inc. Lens delivery system
US8968396B2 (en) 2007-07-23 2015-03-03 Powervision, Inc. Intraocular lens delivery systems and methods of use
EP2629698A4 (fr) * 2010-10-22 2016-08-24 Emmetropia Inc Système de lentille intraoculaire
US9610155B2 (en) 2008-07-23 2017-04-04 Powervision, Inc. Intraocular lens loading systems and methods of use
US9872763B2 (en) 2004-10-22 2018-01-23 Powervision, Inc. Accommodating intraocular lenses
US10045844B2 (en) 2002-02-02 2018-08-14 Powervision, Inc. Post-implant accommodating lens modification
US10159562B2 (en) 2014-09-22 2018-12-25 Kevin J. Cady Intraocular pseudophakic contact lenses and related systems and methods
US10195020B2 (en) 2013-03-15 2019-02-05 Powervision, Inc. Intraocular lens storage and loading devices and methods of use
US10299913B2 (en) 2009-01-09 2019-05-28 Powervision, Inc. Accommodating intraocular lenses and methods of use
US10299910B2 (en) 2014-09-22 2019-05-28 Kevin J. Cady Intraocular pseudophakic contact lens with mechanism for securing by anterior leaflet of capsular wall and related system and method
US10390937B2 (en) 2007-07-23 2019-08-27 Powervision, Inc. Accommodating intraocular lenses
US10433949B2 (en) 2011-11-08 2019-10-08 Powervision, Inc. Accommodating intraocular lenses
US10835373B2 (en) 2002-12-12 2020-11-17 Alcon Inc. Accommodating intraocular lenses and methods of use
US10945832B2 (en) 2014-09-22 2021-03-16 Onpoint Vision, Inc. Intraocular pseudophakic contact lens with mechanism for securing by anterior leaflet of capsular wall and related system and method
US11109957B2 (en) 2014-09-22 2021-09-07 Onpoint Vision, Inc. Intraocular pseudophakic contact lens with mechanism for securing by anterior leaflet of capsular wall and related system and method
US11426270B2 (en) 2015-11-06 2022-08-30 Alcon Inc. Accommodating intraocular lenses and methods of manufacturing
US11938018B2 (en) 2014-09-22 2024-03-26 Onpoint Vision, Inc. Intraocular pseudophakic contact lens (IOPCL) for treating age-related macular degeneration (AMD) or other eye disorders
US12059342B2 (en) 2015-06-10 2024-08-13 Alcon Inc. Intraocular lens materials and components
US12447007B2 (en) 2014-09-22 2025-10-21 Onpoint Vision, Inc. Intraocular pseudophakic contact lens with mechanism for securing by anterior leaflet of capsular wall and related system and method

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6013101A (en) * 1994-11-21 2000-01-11 Acuity (Israel) Limited Accommodating intraocular lens implant
WO2003000154A2 (fr) * 2001-06-22 2003-01-03 David Miller Lentilles intraoculaires d'accommodation ameliorees
WO2004000171A1 (fr) * 2002-06-24 2003-12-31 Sarfarazi Faezeh M Lentille intraoculaire elliptique adaptable
US6767363B1 (en) * 1999-11-05 2004-07-27 Bausch & Lomb Surgical, Inc. Accommodating positive and negative intraocular lens system
WO2005084587A2 (fr) * 2004-03-03 2005-09-15 Akkolens International B.V. Deux elements optiques formant, en combinaison, une lentille de puissance optique variable destinee a etre utilisee en tant que lentille intraoculaire

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6013101A (en) * 1994-11-21 2000-01-11 Acuity (Israel) Limited Accommodating intraocular lens implant
US6767363B1 (en) * 1999-11-05 2004-07-27 Bausch & Lomb Surgical, Inc. Accommodating positive and negative intraocular lens system
WO2003000154A2 (fr) * 2001-06-22 2003-01-03 David Miller Lentilles intraoculaires d'accommodation ameliorees
WO2004000171A1 (fr) * 2002-06-24 2003-12-31 Sarfarazi Faezeh M Lentille intraoculaire elliptique adaptable
WO2005084587A2 (fr) * 2004-03-03 2005-09-15 Akkolens International B.V. Deux elements optiques formant, en combinaison, une lentille de puissance optique variable destinee a etre utilisee en tant que lentille intraoculaire

Cited By (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10045844B2 (en) 2002-02-02 2018-08-14 Powervision, Inc. Post-implant accommodating lens modification
US9277987B2 (en) 2002-12-12 2016-03-08 Powervision, Inc. Accommodating intraocular lenses
US9872762B2 (en) 2002-12-12 2018-01-23 Powervision, Inc. Accommodating intraocular lenses
US8328869B2 (en) 2002-12-12 2012-12-11 Powervision, Inc. Accommodating intraocular lenses and methods of use
US8361145B2 (en) 2002-12-12 2013-01-29 Powervision, Inc. Accommodating intraocular lens system having circumferential haptic support and method
US9855137B2 (en) 2002-12-12 2018-01-02 Powervision, Inc. Accommodating intraocular lenses and methods of use
US9795473B2 (en) 2002-12-12 2017-10-24 Powervision, Inc. Accommodating intraocular lenses
US10835373B2 (en) 2002-12-12 2020-11-17 Alcon Inc. Accommodating intraocular lenses and methods of use
US11751991B2 (en) 2002-12-12 2023-09-12 Alcon Inc. Accommodating intraocular lenses and methods of use
US9872763B2 (en) 2004-10-22 2018-01-23 Powervision, Inc. Accommodating intraocular lenses
US10368979B2 (en) 2006-12-19 2019-08-06 Powervision, Inc. Accommodating intraocular lenses
US8968396B2 (en) 2007-07-23 2015-03-03 Powervision, Inc. Intraocular lens delivery systems and methods of use
US12318279B2 (en) 2007-07-23 2025-06-03 Alcon Inc. Lens delivery system
US11759313B2 (en) 2007-07-23 2023-09-19 Alcon Inc. Lens delivery system
US8956408B2 (en) 2007-07-23 2015-02-17 Powervision, Inc. Lens delivery system
US10350060B2 (en) 2007-07-23 2019-07-16 Powervision, Inc. Lens delivery system
US9855139B2 (en) 2007-07-23 2018-01-02 Powervision, Inc. Intraocular lens delivery systems and methods of use
US10390937B2 (en) 2007-07-23 2019-08-27 Powervision, Inc. Accommodating intraocular lenses
US8314927B2 (en) 2007-07-23 2012-11-20 Powervision, Inc. Systems and methods for testing intraocular lenses
WO2010009257A1 (fr) * 2008-07-15 2010-01-21 Alcon, Inc. Lentille intraoculaire accommodative avec élément optique torique et profondeur de foyer étendue
RU2501054C2 (ru) * 2008-07-15 2013-12-10 Алькон, Инк. Аккомодационная интраокулярная линза (иол) с торическим оптическим элементом и увеличенной глубиной фокуса
JP2011528272A (ja) * 2008-07-15 2011-11-17 アルコン,インコーポレイティド 円環状光学部及び拡張された焦点深度を有する調節性iol
US9610155B2 (en) 2008-07-23 2017-04-04 Powervision, Inc. Intraocular lens loading systems and methods of use
US10299913B2 (en) 2009-01-09 2019-05-28 Powervision, Inc. Accommodating intraocular lenses and methods of use
US11166808B2 (en) 2009-01-09 2021-11-09 Alcon Inc. Accommodating intraocular lenses and methods of use
US10357356B2 (en) 2009-01-09 2019-07-23 Powervision, Inc. Accommodating intraocular lenses and methods of use
US8447086B2 (en) 2009-08-31 2013-05-21 Powervision, Inc. Lens capsule size estimation
US11737862B2 (en) 2010-02-23 2023-08-29 Alcon Inc. Fluid for accommodating intraocular lenses
US8900298B2 (en) 2010-02-23 2014-12-02 Powervision, Inc. Fluid for accommodating intraocular lenses
US12419738B2 (en) 2010-02-23 2025-09-23 Alcon Inc. Fluid for accommodating intraocular lenses
US10980629B2 (en) 2010-02-23 2021-04-20 Alcon Inc. Fluid for accommodating intraocular lenses
US9693858B2 (en) 2010-07-09 2017-07-04 Powervision, Inc. Intraocular lens delivery devices and methods of use
US8668734B2 (en) 2010-07-09 2014-03-11 Powervision, Inc. Intraocular lens delivery devices and methods of use
US9044317B2 (en) 2010-07-09 2015-06-02 Powervision, Inc. Intraocular lens delivery devices and methods of use
US10595989B2 (en) 2010-07-09 2020-03-24 Powervision, Inc. Intraocular lens delivery devices and methods of use
US11779456B2 (en) 2010-07-09 2023-10-10 Alcon Inc. Intraocular lens delivery devices and methods of use
EP2629698A4 (fr) * 2010-10-22 2016-08-24 Emmetropia Inc Système de lentille intraoculaire
US12447006B2 (en) 2011-11-08 2025-10-21 Alcon Inc. Accommodating intraocular lenses
US10433949B2 (en) 2011-11-08 2019-10-08 Powervision, Inc. Accommodating intraocular lenses
US11484402B2 (en) 2011-11-08 2022-11-01 Alcon Inc. Accommodating intraocular lenses
US10195020B2 (en) 2013-03-15 2019-02-05 Powervision, Inc. Intraocular lens storage and loading devices and methods of use
US11071622B2 (en) 2013-03-15 2021-07-27 Alcon Inc. Intraocular lens storage and loading devices and methods of use
US12226309B2 (en) 2013-03-15 2025-02-18 Alcon Inc. Intraocular lens storage and loading devices and methods of use
US11793627B2 (en) 2013-03-15 2023-10-24 Alcon Inc. Intraocular lens storage and loading devices and methods of use
US10299910B2 (en) 2014-09-22 2019-05-28 Kevin J. Cady Intraocular pseudophakic contact lens with mechanism for securing by anterior leaflet of capsular wall and related system and method
US10159562B2 (en) 2014-09-22 2018-12-25 Kevin J. Cady Intraocular pseudophakic contact lenses and related systems and methods
US11583386B2 (en) 2014-09-22 2023-02-21 Onpoint Vision, Inc. Intraocular pseudophakic contact lens with mechanism for securing by anterior leaflet of capsular wall and related system and method
US11571293B2 (en) 2014-09-22 2023-02-07 Onpoint Vision, Inc. Intraocular pseudophakic contact lens with mechanism for securing by anterior leaflet of capsular wall and related system and method
US11432921B2 (en) 2014-09-22 2022-09-06 Onpoint Vision, Inc. Intraocular pseudophakic contact lenses and related systems and methods
US11903818B2 (en) 2014-09-22 2024-02-20 Onpoint Vision, Inc. Intraocular pseudophakic contact lenses and related systems and methods
US11938018B2 (en) 2014-09-22 2024-03-26 Onpoint Vision, Inc. Intraocular pseudophakic contact lens (IOPCL) for treating age-related macular degeneration (AMD) or other eye disorders
US11109957B2 (en) 2014-09-22 2021-09-07 Onpoint Vision, Inc. Intraocular pseudophakic contact lens with mechanism for securing by anterior leaflet of capsular wall and related system and method
US10945832B2 (en) 2014-09-22 2021-03-16 Onpoint Vision, Inc. Intraocular pseudophakic contact lens with mechanism for securing by anterior leaflet of capsular wall and related system and method
US10842614B2 (en) 2014-09-22 2020-11-24 Onpoint Vision, Inc. Intraocular pseudophakic contact lenses and related systems and methods
US12447007B2 (en) 2014-09-22 2025-10-21 Onpoint Vision, Inc. Intraocular pseudophakic contact lens with mechanism for securing by anterior leaflet of capsular wall and related system and method
US12059342B2 (en) 2015-06-10 2024-08-13 Alcon Inc. Intraocular lens materials and components
US11426270B2 (en) 2015-11-06 2022-08-30 Alcon Inc. Accommodating intraocular lenses and methods of manufacturing

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