WO2008024285A3 - Composé antibiotique - Google Patents

Composé antibiotique Download PDF

Info

Publication number
WO2008024285A3
WO2008024285A3 PCT/US2007/018288 US2007018288W WO2008024285A3 WO 2008024285 A3 WO2008024285 A3 WO 2008024285A3 US 2007018288 W US2007018288 W US 2007018288W WO 2008024285 A3 WO2008024285 A3 WO 2008024285A3
Authority
WO
WIPO (PCT)
Prior art keywords
antibiotic compound
actinoplanes
diastereomer
enantiomer
fermentation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2007/018288
Other languages
English (en)
Other versions
WO2008024285A2 (fr
Inventor
Angela Basilio Carnicer
Olga Genilloud
Sheo B Singh
Francisca Vicente
Chaowei Zhang
Deborah L Zink
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme de Espana SA
Merck and Co Inc
Original Assignee
Merck Sharp and Dohme de Espana SA
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sharp and Dohme de Espana SA, Merck and Co Inc filed Critical Merck Sharp and Dohme de Espana SA
Publication of WO2008024285A2 publication Critical patent/WO2008024285A2/fr
Publication of WO2008024285A3 publication Critical patent/WO2008024285A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
    • C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne un nouveau composé antibiotique à spectre large de formule structurale I : (I) ou un de ses sels, esters, énantiomères, diastéréoisomères ou mélanges pharmaceutiquement acceptables, ledit composé étant obtenu par fermentation d'un milieu nutritif avec un Actinoplanes sp.
PCT/US2007/018288 2006-08-23 2007-08-17 Composé antibiotique Ceased WO2008024285A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83949706P 2006-08-23 2006-08-23
US60/839,497 2006-08-23

Publications (2)

Publication Number Publication Date
WO2008024285A2 WO2008024285A2 (fr) 2008-02-28
WO2008024285A3 true WO2008024285A3 (fr) 2008-10-09

Family

ID=39107319

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/018288 Ceased WO2008024285A2 (fr) 2006-08-23 2007-08-17 Composé antibiotique

Country Status (1)

Country Link
WO (1) WO2008024285A2 (fr)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020055465A1 (en) * 2000-08-14 2002-05-09 Wenying Li Nocathiacin antibiotics prepared by biotransformation or chemical methods

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020055465A1 (en) * 2000-08-14 2002-05-09 Wenying Li Nocathiacin antibiotics prepared by biotransformation or chemical methods

Also Published As

Publication number Publication date
WO2008024285A2 (fr) 2008-02-28

Similar Documents

Publication Publication Date Title
WO2007061923A3 (fr) Activateurs de la glucokinase
WO2007125547A3 (fr) Nouveau procédé faisant intervenir des statines et leurs sels acceptables sur le plan pharmaceutique
WO2009048101A1 (fr) Composé amide
WO2007050671A3 (fr) Production fermentaire d'alcools a quatre atomes de carbone
EP2514828A3 (fr) Procédés de production d'ansamitocine
WO2007028135A3 (fr) Composes a base d'imidazopyridine
EP2407471A3 (fr) Procédé de préparation d'une forme cristalline d'analogues de rapamycine
AU2008255733A8 (en) Novel 1,2,3,4-tetrahydroquinoxaline derivative which has, as substituent, phenyl group having sulfonic acid ester structure or sulfonic acid amide structure introduced therein and has glucocorticoid receptor-binding activity
WO2009060835A1 (fr) Nouvelle petite molécule de liaison de l'ubiquitine
WO2009141718A3 (fr) Procédé de préparation d'analogues de la prostaglandine et de leurs intermédiaires
WO2009068463A3 (fr) Préparation de dérivés de dihydropyrrole comme intermédiaires
WO2008136393A1 (fr) Cristaux de composé lactame et leur procédé de fabrication
EP1751502B8 (fr) Emetteur comprenant une pluralite de modes d'exploitation
WO2009066735A1 (fr) Procédé de production de 2-azaadamantane
WO2008052861A3 (fr) Procédé de production de carbonates 1,3-hétéroaromatiques exempts de 4-carboxylate
WO2008069987A3 (fr) Fabrication de butènes et de dérivés de ceux-ci à partir d'éthanol sec
WO2008141097A3 (fr) Composés thérapeutiques
MY152557A (en) 3-aminocyclopentanecarboxamides as chemokine receptor modulators
WO2005009391A3 (fr) Compose antibiotique
CO6341557A2 (es) Derivados nitrogenados de la pancratistatina
WO2007057225A3 (fr) Procede de preparation de montelukast et produits intermediaires utilises pour la preparation
WO2008081476A3 (fr) Procédé d'élaboration de chlorhydrate de duloxétine
WO2006128539A3 (fr) Colorant bleu a base de pigment a indice de couleur bleu 80
WO2006086012A8 (fr) Compose antibiotique
WO2008055988A3 (fr) Procédé de production de (4s)-3,4-dihydroxy-2,6,6-triméthyl-cyclohex-2énone et de ses dérivés

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 07837001

Country of ref document: EP

Kind code of ref document: A2

NENP Non-entry into the national phase

Ref country code: DE

NENP Non-entry into the national phase

Ref country code: RU

122 Ep: pct application non-entry in european phase

Ref document number: 07837001

Country of ref document: EP

Kind code of ref document: A2