WO2008024288A3 - Procédés non invasifs pour l'utilisation d'informations spectrales dans la détérmination de concentrations d'analytes - Google Patents

Procédés non invasifs pour l'utilisation d'informations spectrales dans la détérmination de concentrations d'analytes Download PDF

Info

Publication number
WO2008024288A3
WO2008024288A3 PCT/US2007/018310 US2007018310W WO2008024288A3 WO 2008024288 A3 WO2008024288 A3 WO 2008024288A3 US 2007018310 W US2007018310 W US 2007018310W WO 2008024288 A3 WO2008024288 A3 WO 2008024288A3
Authority
WO
WIPO (PCT)
Prior art keywords
raman
fluorescence
spectral information
analyte concentrations
invasive methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2007/018310
Other languages
English (en)
Other versions
WO2008024288A2 (fr
Inventor
Mihailo V Rebec
Michael P Houlne
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Healthcare LLC
Original Assignee
Bayer Healthcare LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Healthcare LLC filed Critical Bayer Healthcare LLC
Priority to JP2009525575A priority Critical patent/JP2010501252A/ja
Priority to CA002661952A priority patent/CA2661952A1/fr
Priority to EP07837020A priority patent/EP2056716A2/fr
Publication of WO2008024288A2 publication Critical patent/WO2008024288A2/fr
Publication of WO2008024288A3 publication Critical patent/WO2008024288A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Optics & Photonics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Surgery (AREA)
  • Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Emergency Medicine (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

L'invention concerne un procédé non invasif pour la détermination de la concentration d'un analyte à l'aide d'informations spectrales Raman ou de fluorescence. Une bande de lumière de haute intensité est appliquée sur un côté du tissu de la peau. La lumière de haute intensité pénètre dans le tissu cutané et génère un signal Raman ou de fluorescence. Une matière de génération de Raman ou une matière de génération de fluorescence est placée à un endroit aussi proche que possible, de l'autre côté du tissu cutané. La matière de génération de Raman ou de fluorescence est située en général à l'opposé de l'entrée de la lumière de haute intensité appliquée. Le signal Raman ou de fluorescence est recueilli et la concentration d'analyte est déterminée à l'aide du signal Raman collecté.
PCT/US2007/018310 2006-08-22 2007-08-17 Procédés non invasifs pour l'utilisation d'informations spectrales dans la détérmination de concentrations d'analytes Ceased WO2008024288A2 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2009525575A JP2010501252A (ja) 2006-08-22 2007-08-17 スペクトル情報を使用して、分析対象物の濃度を決定する、非侵襲的方法
CA002661952A CA2661952A1 (fr) 2006-08-22 2007-08-17 Procedes non invasifs pour l'utilisation d'informations spectrales dans la determination de concentrations d'analytes
EP07837020A EP2056716A2 (fr) 2006-08-22 2007-08-17 Procédés non invasifs pour l'utilisation d'informations spectrales dans la détérmination de concentrations d'analytes

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83929906P 2006-08-22 2006-08-22
US60/839,299 2006-08-22

Publications (2)

Publication Number Publication Date
WO2008024288A2 WO2008024288A2 (fr) 2008-02-28
WO2008024288A3 true WO2008024288A3 (fr) 2008-11-13

Family

ID=39107321

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/018310 Ceased WO2008024288A2 (fr) 2006-08-22 2007-08-17 Procédés non invasifs pour l'utilisation d'informations spectrales dans la détérmination de concentrations d'analytes

Country Status (5)

Country Link
EP (1) EP2056716A2 (fr)
JP (1) JP2010501252A (fr)
CA (1) CA2661952A1 (fr)
TW (1) TW200819732A (fr)
WO (1) WO2008024288A2 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0606891D0 (en) 2006-04-05 2006-05-17 Council Cent Lab Res Councils Raman Analysis Of Pharmaceutical Tablets
US9662047B2 (en) * 2010-08-05 2017-05-30 Massachusetts Institute Of Technology Portable raman diagnostic system
KR101207695B1 (ko) * 2010-08-11 2012-12-03 서울대학교산학협력단 형광 및 라만 신호 표적에 대한 형광 및 라만 신호 동시검출방법 및 이를 이용한 표적 동시검출용 의학영상장치
CN102821688A (zh) * 2011-04-12 2012-12-12 松下电器产业株式会社 对生物体中所含有的生物体成分的浓度进行测定的方法
US8509868B2 (en) 2011-04-12 2013-08-13 Panasonic Corporation Method for measuring a concentration of a biogenic substance contained in a living body
JP6212303B2 (ja) * 2013-06-28 2017-10-11 景博 内田 糖尿病マーカーの測定方法
CN103529013A (zh) * 2013-10-18 2014-01-22 福建师范大学 一种基于dcdr光谱技术的精浆果糖快速检测的方法
KR101651659B1 (ko) * 2015-02-12 2016-08-30 한국광기술원 광 간섭 단층촬영을 이용한 색소 병변의 정량화 시스템 및 방법
CN114295522B (zh) * 2021-12-28 2024-03-29 华东理工大学 基于振动光谱成像的渗透深度及空间浓度分布的分析方法
TWI890642B (zh) * 2024-12-27 2025-07-11 恆達光電股份有限公司 非侵入式血糖量測方法及其量測裝置

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6070093A (en) * 1997-12-02 2000-05-30 Abbott Laboratories Multiplex sensor and method of use
US20030120137A1 (en) * 2001-12-21 2003-06-26 Romuald Pawluczyk Raman spectroscopic system with integrating cavity
WO2006127766A1 (fr) * 2005-05-25 2006-11-30 Bayer Healthcare Llc Procedes d'utilisation de l'information de spectre raman dans la determination des concentrations d'une substance a analyser

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6070093A (en) * 1997-12-02 2000-05-30 Abbott Laboratories Multiplex sensor and method of use
US20030120137A1 (en) * 2001-12-21 2003-06-26 Romuald Pawluczyk Raman spectroscopic system with integrating cavity
WO2006127766A1 (fr) * 2005-05-25 2006-11-30 Bayer Healthcare Llc Procedes d'utilisation de l'information de spectre raman dans la determination des concentrations d'une substance a analyser

Also Published As

Publication number Publication date
EP2056716A2 (fr) 2009-05-13
CA2661952A1 (fr) 2008-02-28
JP2010501252A (ja) 2010-01-21
TW200819732A (en) 2008-05-01
WO2008024288A2 (fr) 2008-02-28

Similar Documents

Publication Publication Date Title
WO2008024288A3 (fr) Procédés non invasifs pour l'utilisation d'informations spectrales dans la détérmination de concentrations d'analytes
WO2008014132A3 (fr) Dispositif de mesure d'analyte combinatoire et procédé d'utilisation
WO2008014135A3 (fr) Verres de mesure non invasive d'analyte et procédé d'utilisation
WO2007140185A3 (fr) Procédés pour une mesure analytique non invasive
WO2004063713A3 (fr) Determination non invasive de direction et de vitesse de modification d'un analyte
WO2001060246A3 (fr) Analyse multivariable de spectres allant du vert a l'ultraviolet d'echantillons cellulaires et tissulaires
TW200626104A (en) Self-contained test sensor
DE602005027485D1 (de) Vorrichtung zur tiefenselektiven raman-spektroskopie
WO2005012553A3 (fr) Sonde optique in vivo de concentration d'analytes dans la matrice sterile sous l'ongle humain
DE602005026683D1 (de) Faseroptik zum abtasten von analyten und herstellungsverfahren dafür
IL182997A0 (en) Non-invasive measurement system and method for measuring the concentration of an optically-active substance
EP1659405A4 (fr) Biocatpeur et procede de mesure d'une substance a analyser
WO2007041331A3 (fr) Capteur pour muqueuses permettant l'evaluation des constituants tissulaires et sanguins, et procede d'utilisation associe
PL355356A1 (en) Method of taking a physiological sample as well as skin puncturing element, test strip and apparatus for determining concentration of analyte in a physiological sample
WO2007014173A3 (fr) Spectroscopie raman intrinseque
WO2008143651A3 (fr) Système de biodétection in vivo basé sur la réponse optique de polymères électroniques
EP2174135A4 (fr) Appareil et procede de detection d'analyte electrochimique
IL177889A0 (en) Methods and devices for non-invasively measuring quantitative information of substances in living organisms
EP1885281A4 (fr) Stents utilises dans des traitements therapeutiques via des lumieres corporelles et methodes d'utilisation
AU2002322145A1 (en) Measurement of the concentration of substances in living organisms using microdialysis
TW200716965A (en) Methods of using raman spectral information in determining analyte concentrations
IL189281A0 (en) In vitro diagnostic method and kit for identification of human papillomavirus in clinical samples
WO2008058014A3 (fr) Procédé et appareil pour une détection non invasive de contact sonde/tissu cutané
WO2008012650A3 (fr) Dispositif d'immunochromatographie utilisé pour le diagnostic de maladies a partir d'un échantillon
IL180800A0 (en) Apparatus components and methods of using apparatus components to detect the presence of an analyte

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 2009525575

Country of ref document: JP

NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 2661952

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 2007837020

Country of ref document: EP

NENP Non-entry into the national phase

Ref country code: RU

121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 07837020

Country of ref document: EP

Kind code of ref document: A2