WO2008024408A3 - Formulations pharmaceutiques de cannabinoïdes destinées à être appliquées sur la peau et leur procédé d'utilisation - Google Patents

Formulations pharmaceutiques de cannabinoïdes destinées à être appliquées sur la peau et leur procédé d'utilisation Download PDF

Info

Publication number
WO2008024408A3
WO2008024408A3 PCT/US2007/018585 US2007018585W WO2008024408A3 WO 2008024408 A3 WO2008024408 A3 WO 2008024408A3 US 2007018585 W US2007018585 W US 2007018585W WO 2008024408 A3 WO2008024408 A3 WO 2008024408A3
Authority
WO
WIPO (PCT)
Prior art keywords
skin
application
cannabinoids
pharmaceutical formulations
cannabinoid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2007/018585
Other languages
English (en)
Other versions
WO2008024408A2 (fr
Inventor
Najib Babul
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Relmada Therapeutics Inc
Original Assignee
Theraquest Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Theraquest Biosciences Inc filed Critical Theraquest Biosciences Inc
Publication of WO2008024408A2 publication Critical patent/WO2008024408A2/fr
Publication of WO2008024408A3 publication Critical patent/WO2008024408A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7092—Transdermal patches having multiple drug layers or reservoirs, e.g. for obtaining a specific release pattern, or for combining different drugs

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La présente invention concerne des compositions pharmaceutiques d'agonistes des cannabinoïdes destinées à être appliquées sur la peau et leur utilisation pour empêcher ou minimiser le risque qu'un abus d'agonistes des cannabinoïdes et/ou que la toxicité des agonistes des cannabinoïdes soit masqué intentionnellement ou non. La présente invention concerne également un procédé consistant à empêcher ou minimiser le risque qu'un abus d'agonistes des cannabinoïdes et/ou que la toxicité des agonistes des cannabinoïdes soit masqué intentionnellement ou non.
PCT/US2007/018585 2006-08-22 2007-08-22 Formulations pharmaceutiques de cannabinoïdes destinées à être appliquées sur la peau et leur procédé d'utilisation Ceased WO2008024408A2 (fr)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US83911706P 2006-08-22 2006-08-22
US83911506P 2006-08-22 2006-08-22
US60/839,115 2006-08-22
US60/839,117 2006-08-22
US84096906P 2006-08-30 2006-08-30
US84097106P 2006-08-30 2006-08-30
US60/840,969 2006-08-30
US60/840,971 2006-08-30

Publications (2)

Publication Number Publication Date
WO2008024408A2 WO2008024408A2 (fr) 2008-02-28
WO2008024408A3 true WO2008024408A3 (fr) 2008-10-23

Family

ID=39107387

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/018585 Ceased WO2008024408A2 (fr) 2006-08-22 2007-08-22 Formulations pharmaceutiques de cannabinoïdes destinées à être appliquées sur la peau et leur procédé d'utilisation

Country Status (1)

Country Link
WO (1) WO2008024408A2 (fr)

Families Citing this family (99)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8252321B2 (en) 2004-09-13 2012-08-28 Chrono Therapeutics, Inc. Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like
EP2373315A4 (fr) * 2008-11-14 2012-06-27 Scripps Research Inst Procédé et composition se rapportant au ciblage de la mono-acylglycérol lipase
DE102009036485B4 (de) * 2009-08-07 2012-10-04 Lts Lohmann Therapie-Systeme Ag Mittel zur zerstörenden Entsorgung von medizinischen Wirkstoffen in transdermalen therapeutischen Systemen
CA2822738C (fr) 2010-12-22 2021-06-08 Exonoid Medical Devices Ltd. Procede et systeme d'administration de medicament
EP2729148A4 (fr) 2011-07-06 2015-04-22 Parkinson S Inst Compositions et méthodes de traitement de symptômes chez des patients atteints de la maladie de parkinson
EP2968259B1 (fr) 2013-03-14 2022-09-14 SC Laboratories Inc. Concentrés bioactifs et leurs utilisations
RS58759B1 (sr) * 2014-01-22 2019-06-28 4P Therapeutics Transdermalni sistemi koji onemogućavaju zloupotrebu i pogrešnu upotrebu
US20160022627A2 (en) * 2014-04-18 2016-01-28 Mary's Medicinals LLC Transdermal cannabinoid patch
IL294075A (en) 2014-06-30 2022-08-01 Syqe Medical Ltd Flow regulating inhaler
BR112016030829B1 (pt) 2014-06-30 2022-02-22 Syqe Medical Ltd Cartucho de dosagem para dispositivo inalador
US11298477B2 (en) 2014-06-30 2022-04-12 Syqe Medical Ltd. Methods, devices and systems for pulmonary delivery of active agents
WO2016001922A1 (fr) 2014-06-30 2016-01-07 Syqe Medical Ltd. Procédés, dispositifs et systèmes utilisables en vue de l'administration pulmonaire d'agents actifs
MX2017000057A (es) 2014-06-30 2017-06-30 Syqe Medical Ltd Procedimiento y dispositivo para vaporizacion e inhalacion de sustancias aisladas.
EP3160565B1 (fr) 2014-06-30 2021-08-18 Syqe Medical Ltd. Dispositifs et systèmes pour administration pulmonaire d'agents actifs
US10028904B2 (en) 2014-12-04 2018-07-24 Wisconsin Alumni Research Foundation Transdermal cannabinoid formulations
US9375417B2 (en) 2014-12-04 2016-06-28 Mary's Medicinals LLC Transdermal cannabinoid formulations
JP2018511355A (ja) 2015-01-28 2018-04-26 クロノ セラピューティクス インコーポレイテッドＣｈｒｏｎｏ Ｔｈｅｒａｐｅｕｔｉｃｓ Ｉｎｃ． 薬剤送達方法及びシステム
ES2860452T3 (es) * 2015-02-16 2021-10-05 Apirx Pharmaceutical Usa Llc Composiciones cosméticas y tópicas que comprenden cannabigerol y cannabidiol
AU2016225026A1 (en) * 2015-02-27 2017-09-07 Canopy Growth Corporation Compositions comprising combinations of purified cannabinoids, with at least one flavonoid, terpene, or mineral
KR101942677B1 (ko) * 2015-03-02 2019-01-25 히사미쓰 세이야꾸 가부시키가이샤 첩부제
JP2018511127A (ja) 2015-03-12 2018-04-19 クロノ セラピューティクス インコーポレイテッドＣｈｒｏｎｏ Ｔｈｅｒａｐｅｕｔｉｃｓ Ｉｎｃ． 渇望入力及び支援システム
US9962340B2 (en) 2015-06-09 2018-05-08 Life Tech Global, Llc Device and method for the transdermal delivery of cannabidiol
WO2017027553A1 (fr) * 2015-08-11 2017-02-16 KannaInnovations LLC Compositions topiques comprenant des hydroxyacides et des cannabinoïdes pour les soins de la peau
US10272125B2 (en) * 2015-09-14 2019-04-30 Life Tech Global, Llc Transdermal delivery of cannabidiol with other active moieties including cannabinoids
IL260290B2 (en) 2015-12-30 2023-11-01 Corium Inc Systems and methods for long-term percutaneous administration
CA3009599A1 (fr) 2016-01-06 2017-07-13 Syqe Medical Ltd. Traitement therapeutique a faible dose
CN109071750B (zh) 2016-03-08 2022-08-02 生活实验公司 持久化妆品组合物
US11185518B2 (en) 2017-12-19 2021-11-30 Axcess Global Sciences, Llc S-beta-hydroxybutyrate compounds and compositions enriched with S-enantiomer
US10596130B2 (en) 2017-12-19 2020-03-24 Axcess Global Sciences, Llc Non-racemic beta-hydroxybutyrate compounds and compositions enriched with the S-enantiomer and methods of use
US11241403B2 (en) 2016-03-11 2022-02-08 Axcess Global Sciences, Llc Beta-hydroxybutyrate mixed salt compositions and methods of use
US10596129B2 (en) 2017-11-22 2020-03-24 Axcess Global Sciences, Llc Non-racemic beta-hydroxybutyrate compounds and compositions enriched with the R-enantiomer and methods of use
US10973792B2 (en) 2019-02-13 2021-04-13 Axcess Global Sciences, Llc Racemic beta-hydroxybutyrate mixed salt-acid compositions and methods of use
US10245243B1 (en) 2017-12-19 2019-04-02 Axcess Global Sciences, Llc Non-racemic beta-hydroxybutyrate compounds and compositions enriched with the S-enantiomer and methods of use
US10245242B1 (en) 2017-11-22 2019-04-02 Axcess Global Sciences, Llc Non-racemic beta-hydroxybutyrate compounds and compositions enriched with the R-enantiomer and methods of use
US10973786B2 (en) 2016-03-11 2021-04-13 Axcess Global Sciences, Llc R-beta-hydroxybutyrate, S-beta-hydroxybutyrate, and RS-beta-hydroxybutyrate mixed salt compositions
US11103470B2 (en) 2017-11-22 2021-08-31 Axcess Global Sciences, Llc Non-racemic beta-hydroxybutyrate compounds and compositions enriched with the R-enantiomer and methods of use
US10736861B2 (en) 2016-03-11 2020-08-11 Axcess Global Sciences, Llc Mixed salt compositions for producing elevated and sustained ketosis
US10596131B2 (en) 2017-11-22 2020-03-24 Axcess Global Sciences, Llc Non-racemic beta-hydroxybutyrate compounds and compositions enriched with the R-enantiomer and methods of use
US12329734B2 (en) 2017-12-19 2025-06-17 Axcess Global Sciences, Llc Use of S-beta-hydroxybutyrate compounds for induction and maintenance of flow
US12496283B2 (en) 2016-04-19 2025-12-16 Axcess Global Sciences, Llc Administration of R-beta-hydroxybutyrate and related compounds in humans
US12533346B2 (en) 2016-04-19 2026-01-27 Axcess Global Sciences, Llc Administration of berberine metabolites
US11806324B2 (en) 2018-04-18 2023-11-07 Axcess Global Sciences, Llc Beta-hydroxybutyric acid compositions and methods for oral delivery of ketone bodies
US11202769B2 (en) 2017-11-22 2021-12-21 Axcess Global Sciences, Llc Ketone body esters of s-beta-hydroxybutyrate and/or s-1,3-butanediol for modifying metabolic function
US20230346721A1 (en) 2018-04-18 2023-11-02 Axcess Global Sciences, Llc Beta-hydroxybutyric acid compositions and methods for delivery of ketone bodies
US12109182B2 (en) 2016-04-19 2024-10-08 Axcess Global Sciences, Llc Administration of R-beta-hydroxybutyrate and related compounds in humans
US10925843B2 (en) 2018-04-18 2021-02-23 Axcess Global Sciences, Llc Compositions and methods for keto stacking with beta-hydroxybutyrate and acetoacetate
US11944598B2 (en) 2017-12-19 2024-04-02 Axcess Global Sciences, Llc Compositions containing s-beta-hydroxybutyrate or non-racemic mixtures enriched with the s-enatiomer
US12521378B2 (en) 2016-04-19 2026-01-13 Axcess Global Sciences, Llc Administration of R-beta-hydroxybutyrate salt blend and related compounds in humans
KR102393596B1 (ko) 2016-04-22 2022-05-04 리셉터 홀딩스, 인크. 속효성 식물-계 의약 화합물 및 영양 보충제
US10143706B2 (en) 2016-06-29 2018-12-04 Cannscience Innovations, Inc. Decarboxylated cannabis resins, uses thereof and methods of making same
US10568865B2 (en) 2016-08-29 2020-02-25 Canopy Growth Corporation Water soluble compositions comprising purified cannabinoids
US12485129B2 (en) 2016-08-29 2025-12-02 Canopy Growth Corporation Water soluble compositions comprising purified cannabinoids
EA201892396A1 (ru) 2016-12-02 2019-04-30 Ресептор Лайф Сайенсиз, Инк. Быстродействующие растительные лекарственные соединения и биологически активные добавки
EP3565617A1 (fr) 2017-01-06 2019-11-13 Chrono Therapeutics Inc. Dispositifs et methodes d'administration transdermique de medicament
JP2020508991A (ja) * 2017-02-15 2020-03-26 ボタニクス ファーマシューティカルズ リミテッド 乾癬の処置のためのカンナビノイドの製剤
WO2018148786A1 (fr) * 2017-02-15 2018-08-23 Botanix Pharmaceuticals Ltd Formulations de cannabinoïdes pour le traitement de l'acné
WO2018148785A1 (fr) * 2017-02-15 2018-08-23 Botanix Pharmaceuticals Ltd Formulations de cannabinoïdes pour le traitement de la dermatite et de maladies cutanées inflammatoires
WO2018148787A1 (fr) * 2017-02-15 2018-08-23 Botanix Pharmaceuticals Ltd Formulations de cannabinoïdes pour le traitement du psoriasis
CN110769819A (zh) * 2017-02-15 2020-02-07 博塔尼克斯制药有限公司 用于治疗痤疮的大麻素制剂
IL268720B2 (en) * 2017-02-15 2024-09-01 Botanix Pharmaceuticals Ltd Formulations of cannabinoids for the treatment of dermatitis and inflammatory skin diseases
US20210128518A1 (en) * 2017-03-06 2021-05-06 Jack D. Korbutov Cannabinoid-containing dermatological compositions and methods using same
JP6801554B2 (ja) * 2017-03-29 2020-12-16 東洋インキＳｃホールディングス株式会社 皮膚貼付用粘着剤、皮膚用貼付剤、および剥離用シート状部材付き皮膚用貼付剤の製造方法
CN106943235A (zh) * 2017-03-31 2017-07-14 南阳医学高等专科学校 一种剖腹产术后护腹带
CA3074845A1 (fr) 2017-09-13 2019-03-21 Living Proof, Inc. Compositions de protection de couleur
CN111133023B (zh) 2017-09-13 2022-10-18 生活实验公司 持久化妆品组合物
US20210186860A1 (en) * 2017-10-17 2021-06-24 Life Tech Global, Llc Improved Delivery Systems for Moieties Including CBD Enhanced Combinations, Formulations and Chimeras
CN111356501A (zh) 2017-11-20 2020-06-30 生活实验公司 实现持久化妆品性能的属性
US12090129B2 (en) 2017-11-22 2024-09-17 Axcess Global Sciences, Llc Non-racemic beta-hydroxybutyrate compounds and compositions enriched with the R-enantiomer and methods of use
CN107997882A (zh) * 2017-12-07 2018-05-08 云南汉木森生物科技有限责任公司 一种具有抗菌消炎、止痛功效的卫生巾及其制作方法
JP2021506783A (ja) * 2017-12-13 2021-02-22 コリウム， インコーポレイテッド 経皮薬物送達の間にデポを作成するための方法
CN111936126A (zh) 2018-01-24 2020-11-13 博塔尼克斯制药有限公司 用于皮炎和炎症性皮肤病的大麻素给药方案
US10512615B1 (en) 2018-08-27 2019-12-24 Axcess Global Sciences, Llc Compositions and methods for delivering cannabidiol and ketone bodies
US11241401B2 (en) 2020-02-06 2022-02-08 Axcess Global Sciences, Llc Enantiomerically pure r-beta-hydroxybutyrate mixed salt-acid compositions
US11129802B2 (en) 2018-08-27 2021-09-28 Axcess Global Sciences, Llc Compositions and methods for delivering cannabidiol and ketone bodies
US10980772B2 (en) * 2018-08-27 2021-04-20 Axcess Global Sciences, Llc Compositions and methods for delivering tetrahydrocannabinol and ketone bodies
US11419836B2 (en) 2019-02-13 2022-08-23 Axcess Global Sciences, Llc Racemic and near racemic beta-hydroxybutyrate mixed salt-acid compositions
AU2019257739B2 (en) 2018-04-27 2025-01-09 Living Proof, Inc. Long lasting cosmetic compositions
AU2019279884B2 (en) 2018-05-29 2025-01-30 Morningside Venture Investments Limited Drug delivery methods and systems
CA3119992A1 (fr) 2018-11-16 2020-05-22 Morningside Venture Investments Limited Systeme d'administration transdermique de medicaments a regulation thermique
AR117118A1 (es) 2018-11-19 2021-07-14 Receptor Holdings Inc Aminoácidos grasos n-acilados para reducir la variabilidad de absorción en composiciones a base de cannabinoides
WO2020183350A1 (fr) * 2019-03-12 2020-09-17 Radient Technologies Innovations Inc. Kit de timbre transdermique avec des unités posologiques transdermiques
US12472200B2 (en) 2019-05-15 2025-11-18 Axcess Global Sciences, Llc Autobiotic compositions and method for promoting healthy gut microbiome
US11969430B1 (en) 2023-03-10 2024-04-30 Axcess Global Sciences, Llc Compositions containing paraxanthine and beta-hydroxybutyrate or precursor for increasing neurological and physiological performance
US11033553B2 (en) 2019-06-21 2021-06-15 Axcess Global Sciences, Llc Non-vasoconstricting energy-promoting compositions containing ketone bodies
US12167993B2 (en) 2019-06-21 2024-12-17 Axcess Global Sciences, Llc Non-vasoconstricting energy-promoting compositions containing ketone bodies
US11950616B2 (en) 2019-06-21 2024-04-09 Axcess Global Sciences, Llc Non-vasoconstricting energy-promoting compositions containing ketone bodies
US12409131B2 (en) 2019-10-03 2025-09-09 Pike Therapeutics Usa, Inc. Transdermal delivery of dronabinol
CA3156257A1 (fr) 2019-10-03 2021-04-08 Starton Therapeutics, Inc. Administration transdermique de dronabinol
US12186280B2 (en) 2019-10-11 2025-01-07 Pike Therapeutics Inc. Pharmaceutical composition and method for treating seizure disorders
US12016829B2 (en) 2019-10-11 2024-06-25 Pike Therapeutics Inc. Pharmaceutical composition and method for treating seizure disorders
MX2022004258A (es) 2019-10-14 2022-05-26 Pike Therapeutics Inc Entrega transdermica de cannabidiol.
US12268699B2 (en) 2019-10-14 2025-04-08 Pike Therapeutics Inc. Transdermal delivery of tetrahydrocannabinol
US12121617B2 (en) 2019-10-14 2024-10-22 Pike Therapeutics Inc. Transdermal delivery of cannabidiol
US11355822B2 (en) * 2020-01-23 2022-06-07 Duracell U.S. Operations, Inc. Battery peel off assembly for exposing a safety feature comprising an aversive agent
US12186297B2 (en) 2020-08-26 2025-01-07 Axcess Global Sciences, Llc Compositions and methods for increasing lean-to-fat mass ratio
US12109381B2 (en) 2020-08-26 2024-10-08 Babak Ghalili Cannabinoid and menthol transdermal delivery systems and methods
US11141404B1 (en) * 2020-11-18 2021-10-12 Anebulo Pharmaceuticals, Inc. Formulations and methods for treating acute cannabinoid overdose
CN113384558A (zh) * 2021-02-01 2021-09-14 深圳普洛美康材料有限公司 一种递送大麻活性物质的透皮贴剂
AU2022362107A1 (en) 2021-10-11 2024-05-02 Anebulo Pharmaceuticals, Inc. Crystalline forms of a cannabinoid receptor type 1 (cb1) modulator and methods of use and preparation thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030003113A1 (en) * 2001-06-29 2003-01-02 Lewandowski Leon J. Individualized addiction cessation therapy
US20030125659A1 (en) * 2000-05-25 2003-07-03 Wolfgang Fleischer Dosage of transdermal delivery systems

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030125659A1 (en) * 2000-05-25 2003-07-03 Wolfgang Fleischer Dosage of transdermal delivery systems
US20030003113A1 (en) * 2001-06-29 2003-01-02 Lewandowski Leon J. Individualized addiction cessation therapy

Also Published As

Publication number Publication date
WO2008024408A2 (fr) 2008-02-28

Similar Documents

Publication Publication Date Title
WO2008024408A3 (fr) Formulations pharmaceutiques de cannabinoïdes destinées à être appliquées sur la peau et leur procédé d'utilisation
WO2008021394A3 (fr) Formulations pharmaceutiques d'agonistes cannabinoïdes et procédé d'utilisation
WO2008027442A3 (fr) Formulations pharmaceutiques orales anti-abus à base d'opioïdes et procédé d'utilisation
WO2008024490A3 (fr) Formulations pharmaceutiques à usage oral de cannabinoïdes dissuadant les abus et leur procédé d'utilisation
WO2008033351A3 (fr) Formulations multimode de libération prolongée et résistantes à l'abus
WO2007087452A3 (fr) Formulations à libération prolongée empêchant l'usage abusif et méthodes d'utilisation de celles-ci
WO2008076754A3 (fr) Composés et compositions utilisés comme inhibiteurs de l'activité du récepteur cannabinoïde 1
WO2006047516A3 (fr) Composes et compositions servant d'inhibiteurs d'activite de recepteur cannabinoide de type 1
WO2008028965A3 (fr) Inhibiteurs de la protéine phosphatase 1, de gadd34 et du complexe protéine phosphatase 1/gadd34, leur préparation et leurs applications
WO2006096439A3 (fr) Compositions pharmaceutiques destinees au traitement et/ou a la prevention de la schizophrenie et de maladies associees
WO2007136439A3 (fr) Procédés, systèmes et compositions d'hyperporalisation
WO2007095043A3 (fr) Formulations pharmaceutiques
WO2007077560A3 (fr) Compositions cryoprotectrices et procédés d'utilisation de celles-ci
MX2008012400A (es) Azolopirimidinas como inhibidores de actividad de cannabinoide 1.
WO2008010921A3 (fr) Modulateurs de propriétés pharmacocinétiques d'agents thérapeutiques
CL2008000507A1 (es) Preparacion regioespecifica de 42-ester de rapamicina con acido 3-hidroxi-2-(hidroxi metil)-2- metil propionico, protegido con isopropilidencetal; y composicion farmaceutica que comprende a dicho compuesto.
MY146969A (en) Dpp iv inhibitor formulations
WO2008001200A3 (fr) Composition transdermique à stabilité de couleur améliorée
WO2008105383A1 (fr) Dérivé de pyrazole et son utilisation pour des objectifs médicaux
WO2007109523A3 (fr) Procédés de stabilisation de compositions instables de manière oxydative
WO2004009091A8 (fr) Agonistes des recepteurs x du foie
WO2007135562A3 (fr) Nouveaux dérivés d'hydroxyphényle et leurs applications biologiques
WO2008075201A3 (fr) Compositions d'épigallocatéchine-3-gallate destinées au traitement du cancer et à la chimioprotection
AU2007310767A1 (en) New fluorene derivatives, compositions containing the same and use thereof as inhibitors of the protein chaperone HSP 90
WO2008111296A1 (fr) Agent pharmaceutique pour la prévention et le traitement d'une maladie cutanée induite par une kératinisation accélérée

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 07837213

Country of ref document: EP

Kind code of ref document: A2

NENP Non-entry into the national phase

Ref country code: DE

NENP Non-entry into the national phase

Ref country code: RU

122 Ep: pct application non-entry in european phase

Ref document number: 07837213

Country of ref document: EP

Kind code of ref document: A2