WO2008028206A3 - Verfahren zur herstellung von reaktiven einmolekülschichteinheiten - Google Patents

Verfahren zur herstellung von reaktiven einmolekülschichteinheiten Download PDF

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Publication number
WO2008028206A3
WO2008028206A3 PCT/AT2007/000415 AT2007000415W WO2008028206A3 WO 2008028206 A3 WO2008028206 A3 WO 2008028206A3 AT 2007000415 W AT2007000415 W AT 2007000415W WO 2008028206 A3 WO2008028206 A3 WO 2008028206A3
Authority
WO
WIPO (PCT)
Prior art keywords
component
producing reactive
monolayer
units
carbonyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/AT2007/000415
Other languages
English (en)
French (fr)
Other versions
WO2008028206A2 (de
Inventor
Hermann J Gruber
Martin Hoelzl
Christoph D Hahn
Christa Leitner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universitaet Linz
Original Assignee
Universitaet Linz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universitaet Linz filed Critical Universitaet Linz
Publication of WO2008028206A2 publication Critical patent/WO2008028206A2/de
Publication of WO2008028206A3 publication Critical patent/WO2008028206A3/de
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
    • C07K17/14—Peptides being immobilised on, or in, an inorganic carrier
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Nanotechnology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Composite Materials (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Materials Engineering (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Treatments Of Macromolecular Shaped Articles (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Manufacture Of Macromolecular Shaped Articles (AREA)

Abstract

Die vorliegende Erfindung liefert ein Verfahren zur Herstellung von reaktiven molekularen Einmolekülschichten („Monolayer„) -Einheiten, dadurch gekennzeichnet, dass eine mehrfachfunktionelle Monolayer-bildende Komponente mit einer mehrfachfunktionellen Carbonylkomponente, die eine gegebenenfalls latente Carbonylygruppe aufweist und in einem Schritt in eine Carbonylgruppe umgewandelt wird, kovalent verbunden werden, wobei gegebenenfalls die Monolayer-bildende Komponente und die Carbonylkomponente durch eine oder mehrere mehrfachfunktionelle Verbindungskomponente(n) kovalent verbunden werden.
PCT/AT2007/000415 2006-09-04 2007-08-30 Verfahren zur herstellung von reaktiven einmolekülschichteinheiten Ceased WO2008028206A2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT14692006A AT504099B1 (de) 2006-09-04 2006-09-04 Verfahren zur herstellung von reaktiven einmolekülschicht-einheiten
ATA1469/2006 2006-09-04

Publications (2)

Publication Number Publication Date
WO2008028206A2 WO2008028206A2 (de) 2008-03-13
WO2008028206A3 true WO2008028206A3 (de) 2008-05-08

Family

ID=38982484

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/AT2007/000415 Ceased WO2008028206A2 (de) 2006-09-04 2007-08-30 Verfahren zur herstellung von reaktiven einmolekülschichteinheiten

Country Status (2)

Country Link
AT (1) AT504099B1 (de)
WO (1) WO2008028206A2 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8907061B2 (en) 2008-01-11 2014-12-09 Lawrence Livermore National Security, Llc. Nanolipoprotein particles and related methods and systems for protein capture, solubilization, and/or purification
WO2009100201A2 (en) * 2008-02-07 2009-08-13 Lawrence Livermore National Security, Llc Functionalized platform for arrays configured for optical detection of targets and related arrays, methods and systems
US9303273B2 (en) 2008-05-09 2016-04-05 Lawrence Livermore National Security, Llc Nanolipoprotein particles comprising a natural rubber biosynthetic enzyme complex and related products, methods and systems
US8906610B2 (en) 2010-02-08 2014-12-09 The Regents Of The University Of California Using phylogenetic probes for quantification of stable isotope labeling and microbial community analysis
US9644038B2 (en) 2011-12-21 2017-05-09 The Regents Of The University Of California Apolipoprotein nanodiscs with telodendrimer
WO2016049061A1 (en) 2014-09-22 2016-03-31 Lawrence Livermore National Security, Llc Electrochemical flow-cell for hydrogen production and nicotinamide co-factor dependent target reduction, and related methods and systems
WO2017035326A1 (en) 2015-08-25 2017-03-02 Lawrence Livermore National Security, Llc Stable nanolipoprotein particles and related compositions methods and systems
WO2017044899A1 (en) 2015-09-11 2017-03-16 Lawrence Livermore National Security, Llc Synthetic apolipoproteins, and related compositions methods and systems for nanolipoprotein particles formation
US11207422B2 (en) 2017-05-02 2021-12-28 Lawrence Livermore National Security, Llc MOMP telonanoparticles, and related compositions, methods and systems
US12083223B2 (en) 2017-05-02 2024-09-10 Lawrence Livermore National Security, Llc Nanolipoprotein particles and related compositions methods and systems for loading RNA
WO2024040091A1 (en) * 2022-08-19 2024-02-22 Hongene Biotech Corporation Lipid-pegylated compounds, preparations and uses thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002063299A1 (en) * 2001-02-05 2002-08-15 Graffinity Pharmaceuticals Ag Low affinity screening method

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10251229A1 (de) * 2002-03-05 2003-09-25 Univ Ulm Dithiolan-Derivate zur Immobilisierung von Biomolekülen auf Edelmetallen und Halbleitern
US7285674B2 (en) * 2004-05-06 2007-10-23 Interuniversitair Microelektronica Centrum (Imec) Silane molecules with pre-activated and protein-resistant functionalities and silane films comprising such molecules
WO2006048491A1 (es) * 2004-10-28 2006-05-11 Consejo Superior De Investigaciones Científicas Biosensor basado en moléculas de ácido nucleico peptídico (pna) sobre superficies de oro, procedimiento de obtención y sus aplicaciones

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002063299A1 (en) * 2001-02-05 2002-08-15 Graffinity Pharmaceuticals Ag Low affinity screening method

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
HAHN CD ET AL.: "Self-Assembled Monolayers with Latent Aldehydes for Protein Immobilization", BIOCONJUGATE CHEMISTRY, vol. 18, 22 December 2006 (2006-12-22), XP002467344 *
HAHN, CD: "Rekonstitution von Liganden auf Goldoberflächen", May 2005, XP002467345 *
JANG C-H ET AL.: "A Strategy for the Sequential Patterning of Proteins: Catalytically Active Multiprotein Nanofabrication", NANO LETTERS, vol. 3, no. 6, June 2003 (2003-06-01), pages 691 - 694, XP002467342 *
KADA G ET AL: "Dithio-phospholipids for oriented immobilization of proteins to gold surfaces", TETRAHEDRON LETTERS, ELSEVIER, AMSTERDAM, NL, vol. 42, no. 14, 2 April 2001 (2001-04-02), pages 2677 - 2680, XP004231639, ISSN: 0040-4039 *
TINAZLI ALI ET AL: "High-affinity chelator thiols for switchable and oriented immobilization of histidine-tagged proteins: a generic platform for protein chip technologies", CHEMISTRY - A EUROPEAN JOURNAL, VCH PUBLISHERS, US, vol. 11, no. 18, 5 September 2005 (2005-09-05), pages 5249 - 5259, XP002450465, ISSN: 0947-6539 *
YADAVALLI VK ET AL.: "Functionalized Self-Assembled Monolayers on Ultraflat Gold as Platforms for Single Molecule Force Spectroscopy and Imaging", LANGMUIR, vol. 22, 7 July 2006 (2006-07-07), pages 6969 - 6976, XP002467343 *

Also Published As

Publication number Publication date
AT504099A1 (de) 2008-03-15
AT504099B1 (de) 2008-10-15
WO2008028206A2 (de) 2008-03-13

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