WO2008084331A3 - Biomarqeurs pour des troubles rénaux - Google Patents

Biomarqeurs pour des troubles rénaux Download PDF

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Publication number
WO2008084331A3
WO2008084331A3 PCT/IB2007/004395 IB2007004395W WO2008084331A3 WO 2008084331 A3 WO2008084331 A3 WO 2008084331A3 IB 2007004395 W IB2007004395 W IB 2007004395W WO 2008084331 A3 WO2008084331 A3 WO 2008084331A3
Authority
WO
WIPO (PCT)
Prior art keywords
biomarkers
renal disorders
developing
patient
risk
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2007/004395
Other languages
English (en)
Other versions
WO2008084331A2 (fr
Inventor
Solange Moll
Denis Hochstrasser
Pierre Lescuyer
Catherine Zimmermann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hopitaux Universitaires De Geneve
Original Assignee
Hopitaux Universitaires De Geneve
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hopitaux Universitaires De Geneve filed Critical Hopitaux Universitaires De Geneve
Publication of WO2008084331A2 publication Critical patent/WO2008084331A2/fr
Anticipated expiration legal-status Critical
Publication of WO2008084331A3 publication Critical patent/WO2008084331A3/fr
Ceased legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/34—Genitourinary disorders
    • G01N2800/347—Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/50—Determining the risk of developing a disease

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

La présente invention porte sur des procédés pour déterminer si un patient a ou est à risque de développer un trouble rénal. Dans certains modes de réalisation, des biomarqueurs spécifiques sont fournis, lesquels peuvent être utilisés pour déterminer si un patient a ou est à risque de développer un trouble rénal (par exemple, une insuffisance rénale aiguë).
PCT/IB2007/004395 2006-06-21 2007-06-20 Biomarqeurs pour des troubles rénaux Ceased WO2008084331A2 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US80541406P 2006-06-21 2006-06-21
US60/805,414 2006-06-21
US86673306P 2006-11-21 2006-11-21
US60/866,733 2006-11-21

Publications (2)

Publication Number Publication Date
WO2008084331A2 WO2008084331A2 (fr) 2008-07-17
WO2008084331A3 true WO2008084331A3 (fr) 2009-04-23

Family

ID=39609106

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2007/004395 Ceased WO2008084331A2 (fr) 2006-06-21 2007-06-20 Biomarqeurs pour des troubles rénaux

Country Status (1)

Country Link
WO (1) WO2008084331A2 (fr)

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EP1871809A2 (fr) 2005-04-22 2008-01-02 Morphotek, Inc. Anticorps a activite d'effecteur immunitaire et internalises dans des cellules positives vis-a-vis de l'endosialine
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WO2010021696A1 (fr) 2008-08-18 2010-02-25 The Board Of Trustees Of The Leland Stanford Junior University Procédés et compositions pour déterminer un phénotype tolérant à une greffe chez un sujet
NZ610356A (en) 2008-08-28 2015-03-27 Astute Medical Inc Methods and compositions for diagnosis and prognosis of renal injury and renal failure
CA2735590A1 (fr) 2008-08-29 2010-03-04 Astute Medical, Inc. Procedes et compositions pour le diagnostic et le pronostic de la blessure renale et de l'insuffisance renale
NZ607703A (en) * 2008-10-21 2014-09-26 Astute Medical Inc Methods and compositions for diagnosis and prognosis of renal injury and renal failure
CN102264230B (zh) 2008-11-10 2014-12-10 阿斯图特医药公司 用于诊断和预后肾损伤和肾衰竭的方法和组合物
ES2492498T3 (es) 2009-01-15 2014-09-09 The Board Of Trustees Of The Leland Stanford Junior University Panel de biomarcadores para el diagnóstico y la predicción de rechazo de injerto
US9229010B2 (en) 2009-02-06 2016-01-05 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
DE102009010563A1 (de) 2009-02-16 2010-08-26 Matthias W. Engel Vorrichtung zum Nachweis von Analyten in Körperflüssigkeiten
EP2442106B1 (fr) * 2009-06-10 2015-08-19 Masanori Hara Méthode de détection d'une néphropathie diabétique
CA2770393A1 (fr) 2009-08-07 2011-02-10 Astute Medical, Inc. Procedes et compositions pour le diagnostic et le pronostic d'une lesion renale et d'une insuffisance renale
US20130029339A1 (en) 2009-09-09 2013-01-31 The General Hospital Corporation Use of microvesicles in analyzing kras mutations
EP2475988B1 (fr) 2009-09-09 2018-11-14 The General Hospital Corporation Utilisation de microvésicules dans l'analyse de profils d'acide nucléique
EA201290106A1 (ru) * 2009-09-18 2012-12-28 Астьют Медикал, Инк. Способы и композиции для диагностики и прогнозирования повреждения почек и почечной недостаточности
NZ630277A (en) 2009-09-21 2015-02-27 Astute Medical Inc Methods and compositions for diagnosis and prognosis of renal injury and renal failure
EP2496942B1 (fr) 2009-11-07 2017-03-22 Astute Medical, Inc. Méthodes et compositions de diagnostic et de pronostic de lésion rénale et d'insuffisance rénale
EP2507630B1 (fr) 2009-12-02 2017-01-25 The Board of Trustees of The Leland Stanford Junior University Biomarqueurs pour déterminer un xénotype tolérant à l'allogreffe
JP5763098B2 (ja) 2009-12-20 2015-08-12 アスチュート メディカル，インコーポレイテッド 腎損傷および腎不全の診断および予後診断のための方法ならびに組成物
PT2666872T (pt) 2010-02-05 2016-07-08 Astute Medical Inc Processos e composições para o diagnóstico e o prognóstico de lesões renais e de insuficiência renal
EP2531622B1 (fr) * 2010-02-05 2016-04-06 Astute Medical, Inc. Procédés et compositions pour le diagnostic et le pronostic d'une lésion rénale et d'une insuffisance rénale
EP3070474A3 (fr) 2010-02-26 2016-12-07 Astute Medical, Inc. Procedes et compositions pour le diagnostic et le pronostic de lesion renale et d'insuffisance renale
WO2011119980A1 (fr) 2010-03-25 2011-09-29 The Board Of Trustees Of The Leland Stanford Junior University Biomarqueurs protéiques et génétiques pour le rejet de greffes d'organes
NZ605698A (en) 2010-06-23 2015-03-27 Astute Medical Inc Methods and compositions for diagnosis and prognosis of renal injury and renal failure
IN2012MN02812A (fr) 2010-06-23 2015-05-22 Astute Medical Inc
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TW201209171A (en) 2010-07-23 2012-03-01 Harvard College Methods of detecting diseases or conditions using phagocytic cells
EP2596132A4 (fr) 2010-07-23 2013-12-18 Harvard College Procédés de détection de signatures de maladies ou pathologies dans des liquides biologiques
US20130203624A1 (en) 2010-07-23 2013-08-08 President And Fellows Of Harvard College Methods of Detecting Prenatal or Pregnancy-Related Diseases or Conditions
CA2806296A1 (fr) 2010-07-23 2012-01-26 President And Fellows Of Harvard College Procedes de detection de maladies ou d'etats associes au rein
WO2012031008A2 (fr) 2010-08-31 2012-03-08 The General Hospital Corporation Matières biologiques liées au cancer dans des microvésicules
CA2817111C (fr) 2010-11-10 2019-03-05 Exosome Diagnostics, Inc. Procedes d'isolement de particules contenant des acides nucleiques et extraction d'acides nucleiques a partir de celles-ci
ES2382960B1 (es) * 2010-11-18 2013-05-08 Universidad De Jaén Aminopeptidasas como marcadores de daño renal
US8486717B2 (en) 2011-01-18 2013-07-16 Symbolics, Llc Lateral flow assays using two dimensional features
US8962261B2 (en) 2011-04-06 2015-02-24 The Board Of Trustees Of The Leland Stanford Junior University Autoantibody biomarkers for IGA nephropathy
ES2734494T3 (es) 2011-12-08 2019-12-10 Astute Medical Inc Métodos y usos para el diagnóstico de una lesión renal y de una insuficiencia renal
US9874556B2 (en) 2012-07-18 2018-01-23 Symbolics, Llc Lateral flow assays using two dimensional features
TR201807542T4 (tr) 2013-01-17 2018-06-21 Astute Medical Inc Böbrek hasarı ve böbrek yetmezliği teşhisi ve prognozuna yönelik metotlar ve bileşimler.
NZ771629A (en) 2013-03-09 2022-12-23 Harry Stylli Methods of detecting cancer
WO2014164362A1 (fr) 2013-03-09 2014-10-09 Harry Stylli Procédés de détection du cancer de la prostate
ES2528672B1 (es) * 2013-07-10 2015-11-24 Consejo Superior De Investigaciones Científicas (Csic) Neurofilina-1 (NRP-1) urinaria como marcador pronóstico de nefritis y nefritis lúpica
CN108051590B (zh) 2013-09-13 2020-12-11 Symbolics有限责任公司 运用二维试验和对照信号读出模式的侧向层析检测
US10451636B2 (en) 2014-04-09 2019-10-22 The Regents Of The University Of California Protein biomarkers for immune assessment and prediction of transplant rejection
CA2955992A1 (fr) * 2014-07-23 2016-01-28 University Of British Columbia Biomarqueurs de la maladie de fabry
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EP3465201A4 (fr) 2016-06-06 2020-08-26 Astute Medical, Inc. Prise en charge de lésions rénales aiguës au moyen de la protéine de liaison de facteur de croissance insulinomimétique 7 et de l'inhibiteur tissulaire de métalloprotéinase 2
US11346846B2 (en) 2017-02-06 2022-05-31 Astute Medical, Inc. Methods and compositions for diagnosis and prognosis of renal injury and renal failure
CN114441762A (zh) * 2020-11-03 2022-05-06 中山大学附属第三医院 一种评估新型冠状病毒肺炎患者肾脏受累风险的试剂盒
CN114324887B (zh) * 2021-10-14 2025-03-25 深圳市陆为生物技术有限公司 免疫球蛋白a肾病t细胞诊断标志物

Citations (2)

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WO2003082202A2 (fr) * 2002-03-28 2003-10-09 The Regents Of The University Of Michigan Techniques et compositions destinees a l'analyse d'echantillons d'urine en vue du diagnostic et du traitement de maladie renales
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Patent Citations (2)

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WO2003082202A2 (fr) * 2002-03-28 2003-10-09 The Regents Of The University Of Michigan Techniques et compositions destinees a l'analyse d'echantillons d'urine en vue du diagnostic et du traitement de maladie renales
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Non-Patent Citations (1)

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Title
MERRITT S E ET AL: "ANALYSIS OF ALPHA-1 I PROCOLLAGEN ALPHA-1 IV COLLAGEN AND BETA ACTIN MESSENGER RNA IN GLOMERULUS AND CORTEX OF RABBITS WITH EXPERIMENTAL ANTI-GLOMERULAR BASEMENT MEMBRANE DISEASE EVIDENCE FOR EARLY EXTRAGLOMERULAR COLLAGEN BIOSYNTHESIS", LABORATORY INVESTIGATION, UNITED STATES AND CANADIAN ACADEMY OF PATHOLOGY, BALTIMORE, US, vol. 63, no. 6, 1 January 1990 (1990-01-01), pages 762 - 769, XP009108335, ISSN: 0023-6837 *

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