WO2008087367A3 - Derives de (phenylthiazolyl)-phenyl-propan-1-one et de (phenyloxazodyl)-phenyl-propan-1-one substitues, preparations et utilisations - Google Patents

Derives de (phenylthiazolyl)-phenyl-propan-1-one et de (phenyloxazodyl)-phenyl-propan-1-one substitues, preparations et utilisations Download PDF

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Publication number
WO2008087367A3
WO2008087367A3 PCT/FR2007/052635 FR2007052635W WO2008087367A3 WO 2008087367 A3 WO2008087367 A3 WO 2008087367A3 FR 2007052635 W FR2007052635 W FR 2007052635W WO 2008087367 A3 WO2008087367 A3 WO 2008087367A3
Authority
WO
WIPO (PCT)
Prior art keywords
propan
phenyl
phenylthiazolyl
substituted
same
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/FR2007/052635
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English (en)
Other versions
WO2008087367A2 (fr
Inventor
Jean-Francois Delhomel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genfit SA
Original Assignee
Genfit SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genfit SA filed Critical Genfit SA
Publication of WO2008087367A2 publication Critical patent/WO2008087367A2/fr
Publication of WO2008087367A3 publication Critical patent/WO2008087367A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/24—Radicals substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L invention concerne des composés dérivésde (phénylthiazolyl)-phényl- propan-1-one et de phényloxazolyl)-phényl-propan-1-one substitués, les compositions pharmaceutiques les comprenant ainsi que leurs applications thérapeutiques, notamment dans les domaines de la santé humaine et animale.
PCT/FR2007/052635 2006-12-29 2007-12-28 Derives de (phenylthiazolyl)-phenyl-propan-1-one et de (phenyloxazodyl)-phenyl-propan-1-one substitues, preparations et utilisations Ceased WO2008087367A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0656065A FR2910893A1 (fr) 2006-12-29 2006-12-29 Derives de (phenylthiazolyl)-phenyl-propan-1-one et de (phenyloxazolyl)-phenyl-propan-1-one substitues, preparations et utilisations.
FR0656065 2006-12-29

Publications (2)

Publication Number Publication Date
WO2008087367A2 WO2008087367A2 (fr) 2008-07-24
WO2008087367A3 true WO2008087367A3 (fr) 2008-11-06

Family

ID=38257586

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR2007/052635 Ceased WO2008087367A2 (fr) 2006-12-29 2007-12-28 Derives de (phenylthiazolyl)-phenyl-propan-1-one et de (phenyloxazodyl)-phenyl-propan-1-one substitues, preparations et utilisations

Country Status (2)

Country Link
FR (1) FR2910893A1 (fr)
WO (1) WO2008087367A2 (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102009002514A1 (de) * 2009-04-21 2010-10-28 Evonik Degussa Gmbh Verfahren zur Herstellung von substituierten 1,4-Chinonmethiden
US20110092517A1 (en) * 2009-08-14 2011-04-21 Cerenis Therapeutics S.A. & Nippon Chemiphar Co., Ltd. Use of PPAR Delta Ligands for the Treatment or Prevention of Inflammation or Energy Metabolism/Production Related Diseases
WO2011107494A1 (fr) 2010-03-03 2011-09-09 Sanofi Nouveaux dérivés aromatiques de glycoside, médicaments contenants ces composés, et leur utilisation
EP2582709B1 (fr) 2010-06-18 2018-01-24 Sanofi Dérivés d'azolopyridin-3-one en tant qu'inhibiteurs de lipases et de phospholipases
US8530413B2 (en) 2010-06-21 2013-09-10 Sanofi Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments
TW201221505A (en) 2010-07-05 2012-06-01 Sanofi Sa Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament
TW201215388A (en) 2010-07-05 2012-04-16 Sanofi Sa (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
TW201215387A (en) 2010-07-05 2012-04-16 Sanofi Aventis Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament
WO2013037390A1 (fr) 2011-09-12 2013-03-21 Sanofi Dérivés amides d'acide 6-(4-hydroxyphényl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylique en tant qu'inhibiteurs de kinase
EP2760862B1 (fr) 2011-09-27 2015-10-21 Sanofi Dérivés d'amide d'acide 6-(4-hydroxyphényl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylique utilisés comme inhibiteurs de kinase
BR112014030412A2 (pt) 2012-06-14 2017-06-27 Basf Se método para combater ou controlar pragas, método para proteger culturas, compostos, processo para a preparação de compostos, uso de um composto, composição agrícola ou veterinária e semente.
CN103588767B (zh) * 2013-11-20 2016-01-20 苏州明锐医药科技有限公司 达拉菲尼的制备方法
US12053445B2 (en) 2016-03-31 2024-08-06 Genfit Methods of treatment of cholestatic diseases
CN108658908B (zh) * 2017-07-31 2019-05-10 广州必贝特医药技术有限公司 1，3-二取代烯酮类化合物及其应用
WO2021169769A1 (fr) * 2020-02-28 2021-09-02 四川科伦博泰生物医药股份有限公司 Composé aromatique et composition pharmaceutique et utilisation associées
CN115884765A (zh) 2020-08-26 2023-03-31 基恩菲特公司 用于治疗原发性胆汁性胆管炎的组合物和方法
US20240216312A1 (en) 2021-05-11 2024-07-04 Genfit Ppar-agonists for use in the treatment of liver failure
WO2022238448A1 (fr) 2021-05-11 2022-11-17 Genfit Agonistes de dérivés d'elafibranor de ppar destinés à être utilisés dans le traitement de la septicémie

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002050048A1 (fr) * 2000-12-20 2002-06-27 Glaxo Group Limited Thiaoxazoles et oxazoles, utilisation de ces derniers en tant qu'activateurs des recepteurs humains actives par un proliferateur de peroxysomes
WO2002059098A1 (fr) * 2000-12-20 2002-08-01 Glaxo Group Limited Derives de thiazole et d'oxazole en tant qu'activateurs de recepteurs actives par le proliferateur du peroxysome humain
EP1310494A1 (fr) * 2000-08-11 2003-05-14 Nippon Chemiphar Co., Ltd. ACTIVATEURS DE PPAR (delta)
EP1371650A1 (fr) * 2001-03-23 2003-12-17 Nippon Chemiphar Co., Ltd. Activateur de recepteur active par les proliferateurs du peroxysome
EP1424330A1 (fr) * 2001-08-10 2004-06-02 Nippon Chemiphar Co., Ltd. Activateur du recepteur delta sensible au proliferateur de peroxysome
EP1666472A1 (fr) * 2003-09-22 2006-06-07 Ono Pharmaceutical Co., Ltd. Derive d'acide phenylacetique, ainsi que procede de production et utilisation de celui-ci

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1310494A1 (fr) * 2000-08-11 2003-05-14 Nippon Chemiphar Co., Ltd. ACTIVATEURS DE PPAR (delta)
WO2002050048A1 (fr) * 2000-12-20 2002-06-27 Glaxo Group Limited Thiaoxazoles et oxazoles, utilisation de ces derniers en tant qu'activateurs des recepteurs humains actives par un proliferateur de peroxysomes
WO2002059098A1 (fr) * 2000-12-20 2002-08-01 Glaxo Group Limited Derives de thiazole et d'oxazole en tant qu'activateurs de recepteurs actives par le proliferateur du peroxysome humain
EP1371650A1 (fr) * 2001-03-23 2003-12-17 Nippon Chemiphar Co., Ltd. Activateur de recepteur active par les proliferateurs du peroxysome
EP1424330A1 (fr) * 2001-08-10 2004-06-02 Nippon Chemiphar Co., Ltd. Activateur du recepteur delta sensible au proliferateur de peroxysome
EP1666472A1 (fr) * 2003-09-22 2006-06-07 Ono Pharmaceutical Co., Ltd. Derive d'acide phenylacetique, ainsi que procede de production et utilisation de celui-ci

Also Published As

Publication number Publication date
WO2008087367A2 (fr) 2008-07-24
FR2910893A1 (fr) 2008-07-04

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