WO2008102880A1 - 抗真菌症用貼付剤 - Google Patents

抗真菌症用貼付剤 Download PDF

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Publication number
WO2008102880A1
WO2008102880A1 PCT/JP2008/053085 JP2008053085W WO2008102880A1 WO 2008102880 A1 WO2008102880 A1 WO 2008102880A1 JP 2008053085 W JP2008053085 W JP 2008053085W WO 2008102880 A1 WO2008102880 A1 WO 2008102880A1
Authority
WO
WIPO (PCT)
Prior art keywords
skin
patch
drug
mycoses
nails
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2008/053085
Other languages
English (en)
French (fr)
Inventor
Koji Kawahara
Noriko Shimada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nichiban Co Ltd
Original Assignee
Nichiban Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nichiban Co Ltd filed Critical Nichiban Co Ltd
Priority to US12/226,375 priority Critical patent/US20090203797A1/en
Priority to EP08711853A priority patent/EP2113249A4/en
Priority to JP2008534591A priority patent/JP4430120B2/ja
Publication of WO2008102880A1 publication Critical patent/WO2008102880A1/ja
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

　薬剤の結晶析出を防止する溶解剤や、爪及び／又は皮膚への薬剤透過を促す透過促進剤を加えることなく、爪及び／又は皮膚角質層において薬物濃度を長時間高濃度で維持することができ、長時間貼付においても優れた付着性を有し、皮膚刺激性の少ない、真菌症の予防又は治療用の爪及び／又は皮膚用貼付剤を提供する。 　真菌症の予防又は治療用の爪及び／又は皮膚用貼付剤であって、アクリル系粘着剤層又はシリコーン系粘着剤層に、オクタノール／水分配係数であるlogKo/w値が４以上である抗真菌剤を溶解状態で含有する貼付剤。 　
PCT/JP2008/053085 2007-02-23 2008-02-22 抗真菌症用貼付剤 Ceased WO2008102880A1 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US12/226,375 US20090203797A1 (en) 2007-02-23 2008-02-22 Antimycotic Patch
EP08711853A EP2113249A4 (en) 2007-02-23 2008-02-22 Antifungal PLASTER
JP2008534591A JP4430120B2 (ja) 2007-02-23 2008-02-22 抗真菌症用貼付剤

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JPPCT/JP2007/053366 2007-02-23
PCT/JP2007/053366 WO2008105038A1 (ja) 2007-02-23 2007-02-23 抗真菌症用貼付剤

Publications (1)

Publication Number Publication Date
WO2008102880A1 true WO2008102880A1 (ja) 2008-08-28

Family

ID=39710151

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/JP2007/053366 Ceased WO2008105038A1 (ja) 2007-02-23 2007-02-23 抗真菌症用貼付剤
PCT/JP2008/053085 Ceased WO2008102880A1 (ja) 2007-02-23 2008-02-22 抗真菌症用貼付剤

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PCT/JP2007/053366 Ceased WO2008105038A1 (ja) 2007-02-23 2007-02-23 抗真菌症用貼付剤

Country Status (6)

Country Link
US (1) US20090203797A1 (ja)
EP (1) EP2113249A4 (ja)
JP (1) JP4430120B2 (ja)
CN (1) CN101541315A (ja)
RU (1) RU2008146786A (ja)
WO (2) WO2008105038A1 (ja)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010189440A (ja) * 2006-08-28 2010-09-02 Hisamitsu Pharmaceut Co Inc 爪用貼付剤
WO2011096566A1 (ja) * 2010-02-05 2011-08-11 久光製薬株式会社 爪白癬治療用貼付剤
RU2609017C1 (ru) * 2015-08-07 2017-01-30 Павел Куприянович Сазонов Способ лечения грибковых заболеваний ногтей

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5194801B2 (ja) * 2006-02-10 2013-05-08 旭硝子株式会社 ウレタン樹脂の製造方法および粘着剤
JP5546013B2 (ja) * 2008-02-27 2014-07-09 久光製薬株式会社 貼付剤及び包装体
JP5537412B2 (ja) * 2008-02-27 2014-07-02 久光製薬株式会社 貼付製剤
WO2011136330A1 (ja) * 2010-04-30 2011-11-03 ニチバン株式会社 貼付剤とその使用
JP6715071B2 (ja) 2016-04-27 2020-07-01 信越化学工業株式会社 耐加水分解性シリコーン化合物及びその製造方法
WO2025038382A1 (en) * 2023-08-11 2025-02-20 Momentive Performance Materials Inc. Pharmaceutical adhesive compositions

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH10330247A (ja) * 1997-06-02 1998-12-15 Pola Chem Ind Inc 爪用の貼付剤
JP2002363070A (ja) 2001-06-06 2002-12-18 Yuutoku Yakuhin Kogyo Kk 経皮吸収貼付剤
JP2003525641A (ja) 1998-02-12 2003-09-02 ワトソン ファーマスーティカルズ，インコーポレイテッド 爪真菌症の治療用感圧接着性マトリックス・パッチ
JP2005501885A (ja) 2001-09-04 2005-01-20 トロムスドルフ ゲーエムベーハー ウント コンパニー カーゲー アルツナイミッテル 爪の成長の機能障害および疾患を治療するための硬膏
JP2006213650A (ja) 2005-02-03 2006-08-17 Nitto Denko Corp 爪貼付用粘着組成物および爪用貼付剤
WO2007069662A1 (ja) * 2005-12-13 2007-06-21 Nitto Denko Corporation 貼付製剤

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU223343B1 (hu) * 1991-05-20 2004-06-28 Novartis Ag. Allil-amin-származékot tartalmazó gyógyászati készítmények és eljárás azok előállítására
BR9904780A (pt) * 1998-02-09 2000-03-08 Macrochem Corp Esmalte fungicida para unhas e método de uso do mesmo
US20030124176A1 (en) * 1999-12-16 2003-07-03 Tsung-Min Hsu Transdermal and topical administration of drugs using basic permeation enhancers
US6585963B1 (en) * 2001-02-15 2003-07-01 Watson Pharmaceuticals, Inc. Nail compositions and methods of administering same
US20040258739A1 (en) * 2001-09-04 2004-12-23 Rudy Susilo Plaster for the treatment of dysfunctions and disorders of nails
AU2002364893A1 (en) * 2001-10-22 2003-06-17 University Of Mississippi Delivery of medicaments to the nail

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH10330247A (ja) * 1997-06-02 1998-12-15 Pola Chem Ind Inc 爪用の貼付剤
JP2003525641A (ja) 1998-02-12 2003-09-02 ワトソン ファーマスーティカルズ，インコーポレイテッド 爪真菌症の治療用感圧接着性マトリックス・パッチ
JP2002363070A (ja) 2001-06-06 2002-12-18 Yuutoku Yakuhin Kogyo Kk 経皮吸収貼付剤
JP2005501885A (ja) 2001-09-04 2005-01-20 トロムスドルフ ゲーエムベーハー ウント コンパニー カーゲー アルツナイミッテル 爪の成長の機能障害および疾患を治療するための硬膏
JP2006213650A (ja) 2005-02-03 2006-08-17 Nitto Denko Corp 爪貼付用粘着組成物および爪用貼付剤
WO2007069662A1 (ja) * 2005-12-13 2007-06-21 Nitto Denko Corporation 貼付製剤

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
ALBERTI I. ET AL.: "In vivo assessment of enhanced topical delivery of terbinafine to human serum corneum", J. CONTROL RELEASE, vol. 71, no. 3, 2001, pages 319 - 327, XP004234529 *
KANIKKANNAN N. ET AL., SKIN PERMEATION ENHANCEMENT EFFECT AND SKIN IRRITATION OF SATURATED FATTY ALCOHOLS, 2002, pages 6
MATSUMOTO, T. ET AL.: "Clinical and Pharmacokinetic Study of Orally Administered Terbinafine for Tinea Unguium", NISHI NIHON HIFUKA, vol. 56, no. 2, 1994
See also references of EP2113249A4 *
TANOJO H. ET AL.: "In vitro human barrier modulation by topical application of fatty acids", SKIN PHARMACOL. APPL. SKIN PHYSIOL., vol. 11, no. 2, 1998, XP008012705, DOI: doi:10.1159/000029813

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010189440A (ja) * 2006-08-28 2010-09-02 Hisamitsu Pharmaceut Co Inc 爪用貼付剤
WO2011096566A1 (ja) * 2010-02-05 2011-08-11 久光製薬株式会社 爪白癬治療用貼付剤
JPWO2011096566A1 (ja) * 2010-02-05 2013-06-13 久光製薬株式会社 爪白癬治療用貼付剤
US8574621B2 (en) 2010-02-05 2013-11-05 Hisamitsu Pharmaceutical Co., Inc. Adhesive patch for treatment of tinea unguium
RU2609017C1 (ru) * 2015-08-07 2017-01-30 Павел Куприянович Сазонов Способ лечения грибковых заболеваний ногтей

Also Published As

Publication number Publication date
RU2008146786A (ru) 2010-06-10
EP2113249A4 (en) 2012-09-12
WO2008105038A1 (ja) 2008-09-04
CN101541315A (zh) 2009-09-23
JP4430120B2 (ja) 2010-03-10
JPWO2008102880A1 (ja) 2010-05-27
EP2113249A1 (en) 2009-11-04
US20090203797A1 (en) 2009-08-13

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