WO2009005647A3 - Composés et procédé de préparation d'intermédiaires chiraux pour la synthèse de la proxétine - Google Patents

Composés et procédé de préparation d'intermédiaires chiraux pour la synthèse de la proxétine Download PDF

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Publication number
WO2009005647A3
WO2009005647A3 PCT/US2008/007870 US2008007870W WO2009005647A3 WO 2009005647 A3 WO2009005647 A3 WO 2009005647A3 US 2008007870 W US2008007870 W US 2008007870W WO 2009005647 A3 WO2009005647 A3 WO 2009005647A3
Authority
WO
WIPO (PCT)
Prior art keywords
paroxetine
compounds
synthesis
chiral intermediates
prepare chiral
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2008/007870
Other languages
English (en)
Other versions
WO2009005647A2 (fr
Inventor
Robert William Scott
Sean Timothy Neville
Lishan Zhao
Ningqing Ran
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BIOVERDANT Inc
Original Assignee
BIOVERDANT Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BIOVERDANT Inc filed Critical BIOVERDANT Inc
Publication of WO2009005647A2 publication Critical patent/WO2009005647A2/fr
Publication of WO2009005647A3 publication Critical patent/WO2009005647A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La présente invention concerne des composés et des procédés qui produisent des intermédiaires et des précurseurs de la paroxétine et composés associés. L'invention concerne également des procédés de préparation de la paroxétine.
PCT/US2008/007870 2007-06-27 2008-06-24 Composés et procédé de préparation d'intermédiaires chiraux pour la synthèse de la proxétine Ceased WO2009005647A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93746607P 2007-06-27 2007-06-27
US60/937,466 2007-06-27

Publications (2)

Publication Number Publication Date
WO2009005647A2 WO2009005647A2 (fr) 2009-01-08
WO2009005647A3 true WO2009005647A3 (fr) 2009-04-09

Family

ID=40076855

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/007870 Ceased WO2009005647A2 (fr) 2007-06-27 2008-06-24 Composés et procédé de préparation d'intermédiaires chiraux pour la synthèse de la proxétine

Country Status (1)

Country Link
WO (1) WO2009005647A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11986006B2 (en) 2018-08-31 2024-05-21 Mars, Incorporated Anthocyanin-based colorant compositions and methods of use thereof

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HUE044896T2 (hu) 2010-06-22 2019-11-28 Sun Pharmaceutical Industries Australia Pty Ltd Metil-transzferáz nukleinsavak és polipeptidek
ES2664569T3 (es) 2010-07-22 2018-04-20 Sun Pharmaceutical Industries (Australia) Pty Limited Citocromo P450 de plantas
GB201204407D0 (en) 2012-03-13 2012-04-25 Glaxosmithkline Australia Pty Ltd Nucleic acid molecule
CN104262255A (zh) * 2014-09-22 2015-01-07 四川大学 一种不对称催化合成γ-硝基吡唑酰胺化合物的方法
CN104892491B (zh) * 2015-05-06 2017-05-17 浙江海森药业有限公司 一种合成帕罗西汀手性中间体的方法
CN105400758A (zh) * 2015-11-26 2016-03-16 青岛康原药业有限公司 一种氯化钠-氨水、丙酮协同纯化胰激肽酶原的方法及提高胰激肽酶原稳定性的药物组合物
CN115135169A (zh) * 2019-10-01 2022-09-30 马斯公司 花青素苷的酶处理
CN114214375B (zh) * 2021-12-27 2024-03-19 江苏威凯尔医药科技有限公司 (r)-3-(4-卤代-1h-吡唑-1-基)-3-环戊基丙酸酯的制备方法
CA3257053A1 (fr) 2022-05-14 2023-11-23 Novozymes A/S Compositions et procédés de prévention, de traitement, de suppression et/ou d'élimination d'infestations et d'infections phytopathogènes

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993022284A1 (fr) * 1992-05-06 1993-11-11 Smithkline Beecham Plc Procede d'hydrolyse stereospecifique de derives de piperidinedione

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993022284A1 (fr) * 1992-05-06 1993-11-11 Smithkline Beecham Plc Procede d'hydrolyse stereospecifique de derives de piperidinedione

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
D. A. GREENHALGH ET AL.: "A Novel Chiral Base Mediated Glutarimide Desymmetrisation: Application to the Asymmetric Synthesis of (-)-Paroxetine", SYNLETT, no. 12, 2 December 2002 (2002-12-02), GEORG THIEME VERLAG, STUTTGART; DE, pages 2074 - 2076, XP002513234, ISSN: 0936-5214 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11986006B2 (en) 2018-08-31 2024-05-21 Mars, Incorporated Anthocyanin-based colorant compositions and methods of use thereof

Also Published As

Publication number Publication date
WO2009005647A2 (fr) 2009-01-08

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