WO2009008853A1 - Dispositif de séparation et appareil de réaction chimique fabriqués à partir de diamant polycristallin, appareils incluant ces dispositifs tels que des appareils de séparation, et procédés d'utilisation. - Google Patents

Dispositif de séparation et appareil de réaction chimique fabriqués à partir de diamant polycristallin, appareils incluant ces dispositifs tels que des appareils de séparation, et procédés d'utilisation. Download PDF

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Publication number
WO2009008853A1
WO2009008853A1 PCT/US2007/012879 US2007012879W WO2009008853A1 WO 2009008853 A1 WO2009008853 A1 WO 2009008853A1 US 2007012879 W US2007012879 W US 2007012879W WO 2009008853 A1 WO2009008853 A1 WO 2009008853A1
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WO
WIPO (PCT)
Prior art keywords
separation device
chemical
stationary phase
fluid
separation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2007/012879
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English (en)
Inventor
Michael A. Vail
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
US Synthetic Corp
Original Assignee
US Synthetic Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by US Synthetic Corp filed Critical US Synthetic Corp
Priority to EP07809264A priority Critical patent/EP2035823B1/fr
Priority to PCT/US2007/012879 priority patent/WO2009008853A1/fr
Priority to AT07809264T priority patent/ATE547704T1/de
Publication of WO2009008853A1 publication Critical patent/WO2009008853A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6052—Construction of the column body
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/50—Conditioning of the sorbent material or stationary liquid
    • G01N30/52—Physical parameters
    • G01N2030/524—Physical parameters structural properties
    • G01N2030/525—Physical parameters structural properties surface properties, e.g. porosity

Definitions

  • the present invention relates to chromatography, separation, and chemical reaction apparatuses. More particularly, the present invention relates to a porous polycrystalline diamond structure that may be employed as a separation device in a separation apparatus for separating at least one reaction product of a chemical reaction, as a stationary phase support and/or stationary phase in chromatography or separation apparatuses, or as a chemical reaction apparatus for conducting a chemical reaction therein.
  • FIG. 1 shows a typical chromatography apparatus 10 in accordance with the prior art.
  • the chromatography apparatus 10 includes a mobile phase supply 12 holding a mobile phase or carrier fluid 13 that is typically, a solvent in liquid chromatography and an inert gas in gas chromatography.
  • the mobile phase supply 12 is coupled to a pump 14 via a fluid line 16.
  • the pump 14 is operable to pump the mobile phase 13 from the mobile phase supply 12 to a mixture injection port 20 via fluid line 18.
  • the pump 14 pumps the mobile phase 13, which sweeps the sample 22 through the mixture injection port 20 and a feed line 26, and into a packed column 28 having a stationary phase support 38 (FIG. 2).
  • the packed column 28 may be surrounded by a heating element 34 that is operable to heat the packed column 28 to a desired temperature.
  • a detector 32 is coupled to the packed column 28 via a fluid line 30 to receive the different chemical constituents of the sample 22 separated by the packed column 28 and is configured to indicate the presence and/or concentration of chemical constituents of the sample 22 being analyzed by measuring a property that is related to the concentration and/or characteristic of the chemical constituents.
  • the packed column 28 includes a tubular housing 36 formed from a glass, metal, or polymer that encloses and supports the stationary phase support 38.
  • the stationary phase support 38 can be made from is diamond powder, silica powder, and graphitic powder that define a generally granular porous structure through which the mixture of the mobile phase 13 and the sample 22 can pass through.
  • the powdered materials may serve as a stationary phase if the chemical constituents of the sample 22 have different affinities to the powdered materials. However, sometimes the powdered materials may be coated with a liquid, an adsorbent, or chemical species that functions as the stationary phase and the powdered material merely serves as a support structure.
  • the housing 36 has a liner 40 coating the interior thereof to help reduce chemical activity between the sample 22 and the housing 36.
  • the liner 40 can be formed from an inert material such as polytetrafluoroethylene (“PTFE”) or a metallic material such as stainless steel or nickel.
  • PTFE polytetrafluoroethylene
  • metallic material such as stainless steel or nickel.
  • the flow 42 of the constituents 42a and 42b are collected as they emerge from the packed column 28 and the detector 32 analyzes the flow 42 by measuring a property that is related to the concentration and characteristic of the chemical constituents 42a and 42b such as the refractive index or ultra-violet absorbance in order to identify the chemical composition and concentration of the constituents 42a and 42b.
  • the signal from the detector 32 can be displayed on a computer (not shown) or another display device.
  • One problem with the prior art chromatography apparatus 10 is that a highly basic or acidic mobile phase 13 and/or sample 22 can chemically attack and degrade the liner 40 and/or the stationary phase support 38. This degradation can be further exacerbated at high temperatures.
  • a PTFE liner 40 is limited to temperatures below 200 0 C. Degradation of the liner 40 and the stationary phase support 38 can introduce error into any subsequent chemical analysis performed by the detector 32 on the constituents 42a and 42b.
  • the present invention relates to a porous polycrystalline diamond structure that may be employed as a separation device in a separation apparatus for separating at least one reaction product of a chemical reaction, as a stationary phase support and/or stationary phase in chromatography or separation apparatuses, or as a chemical reaction apparatus for conducting a chemical reaction therein.
  • One aspect of the present invention is directed to a separation device comprised of polycrystalline diamond for use in a separation apparatus.
  • the separation device comprises a body of sintered diamond particles.
  • the body includes a proximal inlet end, a distal outlet end, and an intermediate region therebetween.
  • the body further includes a plurality of at least partially interconnected pores that extend between the proximal inlet end and the distal outlet end.
  • the at least partially interconnected pores are capable of communicating fluid from the proximal inlet end to the distal outlet end.
  • the chemical structure of the diamond internal surfaces of the at least partially interconnected pores function as a stationary phase and, thus, the body of the separation device itself serves as the stationary phase.
  • a stationary phase may be disposed within the at least partially interconnected pores of the separation device and, thus, the separation device serves as a stationary phase support.
  • a further aspect of the present invention is directed to a separation apparatus that may be used in gas/liquid chromatography or for separating at least one reaction product from a chemical reaction.
  • the separation apparatus includes a fluid supply system operable to provide a fluid.
  • a separation device is coupled to the fluid supply system to receive the fluid therefrom.
  • the separation device comprises a body of sintered diamond particles.
  • the body includes a proximal inlet end, a distal outlet end, and an intermediate region therebetween.
  • the body further includes a plurality of at least partially interconnected pores that extend between the proximal inlet end and the distal outlet end. The at least partially interconnected pores are capable of communicating fluid from the proximal inlet end to the distal outlet end.
  • the fluid provided by the fluid supply system flows through the passageways of the body of the separation device.
  • chemical constituents of the fluid may be separated as they pass through the passageways and emerge from separation device at different rates where they can be analyzed, such as in chromatography, or further processed.
  • different reagents may be flowed through the separation device to react within the separation device.
  • the at least partially interconnected pores of the separation device may be structured to allow at least one reaction product to exit through the distal outlet end, while waste product exits through another portion in the separation device.
  • a further aspect of the present invention is directed to a chemical reaction apparatus comprised of polycrystalline diamond that may be employed for conducting a chemical reaction therein.
  • the chemical reaction apparatus comprises a body of sintered diamond particles.
  • the body includes a proximal inlet end, a distal outlet end, and an intermediate region therebetween.
  • the body further includes a plurality of at least partially interconnected pores that extend between the proximal inlet end and the distal outlet end. The at least partially interconnected pores are capable of communicating fluid from the proximal inlet end to the distal outlet end.
  • At least one chemical constituent may be flowed into the at least partially interconnected pores of the body and a chemical reaction occurs therein, such as cracking of the at least one chemical constituent or reaction with other chemical constituents that are also flowed into the at least partially interconnected pores of the body.
  • FIG. 1 is a functional block diagram of a chromatography apparatus in accordance with the prior art.
  • FIG. 2 is a schematic cross-sectional view of the packed column of FIG. 1.
  • FIG. 3 is a schematic isometric view of a stationary phase support in accordance with one embodiment of the present invention.
  • FIG. 4 is a transverse schematic cross-sectional view of the stationary phase support of FIG. 3.
  • FIG. 5 is a longitudinal schematic cross-sectional view of the stationary phase support of FIG. 3.
  • FIG. 6 is a functional block diagram of a chromatography apparatus in accordance with one embodiment of the present invention.
  • FIG. 7 is a schematic cross-sectional view of a column utilizing the stationary phase support of FIGS. 3 through 5 in accordance with one embodiment of the present invention. [019] FIG.
  • FIG. 8 is a schematic cross-sectional view of a separation device that may be used for selectively separating at least one reaction product of a chemical reaction that is carried out within the separation device in accordance with another embodiment of the present invention.
  • the present invention relates to a porous polycrystalline diamond structure that may be employed as a separation device in a separation apparatus for separating at least one reaction product of a chemical reaction, as a stationary phase support and/or stationary phase in chromatography or separation apparatuses, or as a chemical reaction apparatus for conducting a chemical reaction therein.
  • a separation apparatus for separating at least one reaction product of a chemical reaction
  • stationary phase support and/or stationary phase in chromatography or separation apparatuses or as a chemical reaction apparatus for conducting a chemical reaction therein.
  • FIGS. 3 through 5 show a stationary phase support 50 in accordance with one embodiment of the present invention.
  • the stationary phase support 50 may be used in gas ⁇ iquid chromatography apparatuses and other chemical processing apparatuses.
  • the stationary phase support 50 includes a body 60 having a proximal inlet end 52, a distal outlet end 54, and an intermediate region 56 therebetween with a peripheral surface 58.
  • the body 60 is formed of a mass of sintered diamond particles having a plurality of at least partially interconnected pores therein.
  • diamond particles typically comprises a single crystal or grain of diamond. However, diamond particles may also be polycrystalline.
  • the body 60 is shown in FIGS. 3 through 5 having a generally cylindrical shape, a variety of other geometries may be used, without limitation.
  • the at least partially interconnecting network of pores form a plurality of passageways 62 (shown in phantom in FIG. 3) that extend from the inlet end 52 to the outlet end 54.
  • the passageways 62 are structured to enable fluids, such as gases or liquids, to flow into the body 60 through the inlet end 52, pass through the intermediate region 56, and exit through the outlet end 54 (or vice-versa).
  • a substantially non-porous diamond coating 64 is formed on the peripheral surface 58 of the body 60 to seal the peripheral surface 58 so that fluid cannot enter or exit through the peripheral surface 58.
  • the substantially non- porous diamond coating 64 may at least partially fill any pores distributed on the peripheral surface 58.
  • the stationary phase support 50 is used as the stationary phase in a separation or chromatography apparatus.
  • the diamond particles that comprise the body 60 have suitable chemical characteristics for separating particular chemical constituents of a sample being analyzed.
  • the stationary phase support 50 also functions as the stationary phase in a separation or chromatography apparatus.
  • At least a portion of selected interior diamond surfaces of the pores of the body 60 that define the passageways 62 may be chemically modified, such as with hydroxyl groups, so that different chemical constituents in a sample to be analyzed will have varying degrees of affinity to the body 60 of sintered diamond particles.
  • U.S. Patent Application Publication US2004/0118762 to Xu et al discloses methods for chemically modifying diamond surfaces that are chemically stable in highly basic solutions.
  • a stationary phase such as, for example, a liquid, an adsorbent, or another substance may at least partially coat or cover selected interior diamond surfaces of the body 60 that define the passageways 62.
  • suitable stationary phases that may be disposed within the passageways 62 are polymeric stationary phases, porous graphitized carbon, C 6 hydrocarbons, C 8 hydrocarbons, Ci 2 hydrocarbon, Ci 8 hydrocarbons, cyclohexyl, phenyl, or another suitable stationary phase.
  • the body 60 may be formed from sintered diamond particles having a variety of different particles sizes.
  • the diamond particles may have an average particle size from about 1 nm to about 1000 ⁇ m, and more typically from about 2 ⁇ m to about 150 ⁇ m.
  • the body 60 is formed by sintering diamond particles having a selected average particle size or a selected multi- mode distribution of diamond particle sizes using an ultra-high pressure, ultra-high temperature (“HPHT") process.
  • HPHT ultra-high pressure, ultra-high temperature
  • the sintering may be effected in an ultra-high pressure press at process conditions of, for example, a pressure of at least about 40 kilobar (e.g., about 50 kilobar to about 70 kilobar) and a temperature of at least about 1000 0 C (e.g., about 1100 0 C to about 1600 0 C) for a time sufficient to consolidate and form a coherent mass of bonded diamond grains.
  • a pressure of at least about 40 kilobar e.g., about 50 kilobar to about 70 kilobar
  • a temperature of at least about 1000 0 C (e.g., about 1100 0 C to about 1600 0 C) for a time sufficient to consolidate and form a coherent mass of bonded diamond grains.
  • the peripheral surface 58 of the body 60 may be coated with the substantially non-porous diamond coating 64.
  • the substantially non-porous diamond coating 64 may be diamond deposited by chemical vapor deposition ("CVD"), physical vapor deposition (“PVD”), or another suitable deposition process that is capable of depositing a substantially non-porous diamond layer.
  • CVD chemical vapor deposition
  • PVD physical vapor deposition
  • multiple bodies 60 may be positioned adjacent to one another so that a distal end 54 of one body 60 abuts or adjoins to a proximal end 52 of another body 60 to construct a larger stationary phase support 50.
  • the multiple bodies 60 may be coated with the substantially non-porous diamond coating 64, as described above, to cover and seal the peripheral surfaces 58 thereof and join the multiple bodies 60 together.
  • the number of the stationary phase supports 50 positioned end-to-end is limited only by the size of the deposition chamber for depositing the substantially non-porous diamond coating 64.
  • the pore size of the body 60 may be varied along the length of the body 60.
  • the pore size may be varied by layering different sized diamond grains.
  • a first half of the intermediate region 56 of the body 60 may be formed from diamond particles having a first average particle size and the second half of the intermediate region 56 may be formed from diamond particles having a second average particle size different than the first diamond particle size.
  • more than two regions of the body 60 of the stationary phase support 50 may exhibit different pores sizes.
  • a pore size of a selected region of the body 60 may be tailored by selection of the precursor diamond particle size and the sintering pressure.
  • the pore size may vary radially in the body 60 or a variety of other pore configurations may be used, without limitation.
  • FIG. 6 shows a chromatography apparatus 80 that utilizes the stationary phase support 50 in accordance with the one embodiment of the present invention.
  • the chromatography apparatus 80 is suitable for use in gas and liquid chromatography.
  • the chromatography apparatus 80 includes a fluid supply system 82.
  • the fluid supply system 82 includes a mobile phase supply 81 holding a mobile phase 84 that is typically, a solvent in liquid chromatography and an inert gas (e.g. , He, N 2 , or H 2 ) in gas chromatography.
  • the mobile phase supply 81 is coupled to a pump 86 via a fluid line 88.
  • the pump 86 is operable to pump the mobile phase 84 from the mobile phase supply 81 to a mixture injection port 92 via a fluid line 90.
  • the fluid supply system 82 further includes a sample supply 96, holding a sample 98 to be analyzed, that is also coupled to the mixture injection port 92 through a fluid line 94.
  • the pump 86 pumps the mobile phase 84, which sweeps the sample 98 through the mixture injection port 92 and a fluid line 100, and into a column 102 having a stationary phase support 50 (FIGS. 3-5).
  • the sample 98 is a gas or a volatile liquid swept into the column 102 by a gaseous mobile phase 84
  • liquid chromatography the sample 98 is a liquid phase that is dissolved by a solvent mobile phase 84.
  • capillary action or gravity may be used to effect movement of the mobile phase 84 and the sample 98 through the mixture injection port 92 and into the column 102, or another suitable introduction technique.
  • a heating element 104 such as, for example, resistance heating elements may be positioned proximate to or in the column 102 for heating the stationary phase support 50 (FIGS. 3-5) to a desired temperature. In gas chromatography, the heating element 104 may be used for vaporizing a volatile liquid sample 98 upon the sample 98 entering the stationary phase support 50.
  • the chromatography apparatus 80 further includes a detector 108 that is coupled to the column 102 via a fluid line 106 to receive the different chemical constituents of the sample 98 separated by the stationary phase support 50 (FIGS. 3-5) of the column 102.
  • the detector 108 is configured to indicate the identity and concentration of chemical constituents of the sample 98 being analyzed by measuring a property that may be related to the concentration and/or characteristic of the chemical constituents.
  • the detector 102 may be a thermal conductivity detector, a flame ionization detector, an electron capture detector, a flame photometric detector, an atomic emission detector, a mass spectrometer, a Fourier transform infrared spectrophotometer, an ultraviolet absorbance detector, an electrochemical detector, or another suitable analytical instrument capable of determining the identity and/or concentration of chemical constituents separated by the column 102.
  • the signal output from the detector 108 is transmitted to a computer 109 or other display device for storing and displaying the collected data in a useful manner such as a graphical display.
  • the mobile phase 84 and the sample 98 are introduced into the column 102 through the mixture injection port 92.
  • Mixture 110 of the mobile phase 84 and the sample 98 enter the stationary phase support 50 through the inlet end 52 thereof.
  • the chemical constituents of the mixture 1 10, and in particular the sample 98 are slowed by their respective affinity for the stationary phase support 50 or a stationary phase disposed within the passageways 62 (FIGS. 3-5) of the stationary phase support 50.
  • a flow 1 14 of different chemical constituents 1 14a and 1 14b of the mixture 1 10 emerge from the outlet end 54 of the stationary phase support 50 of the column 102 at different times.
  • a chemical constituent 1 14a with the least affinity for the stationary phase support 50 or a stationary phase disposed within the passageways 62 (FIGS. 3-5) of the stationary phase support 50 flows through the stationary phase support 50 at a relatively fast rate and emerges first from the outlet end 54, while the chemical constituent 114b with the greatest affinity for the stationary phase support 50 or a stationary phase disposed within the passageways 62 (FIGS. 3-5) of the stationary phase support 50 flows at a relatively slower rate and emerges at a later time from the outlet end 54.
  • the flow 114 of the chemical constituents 1 14a and 114b are collected as they emerge from the outlet end 54 of the stationary phase support 50, and the detector 108 analyzes the flow by measuring a property that is related to the concentration and/or characteristic of the chemical constituents 114a and 114b using any of the aforementioned detection techniques.
  • the chromatography apparatus 80 is merely one embodiment of a separation apparatus that may be used with the various embodiments of stationary phase supports and stationary phases disclosed herein. Many modifications and adaptations to the chromatography apparatus 80 will be apparent to one of ordinary skill in the art such as modifications to the various components of the fluid supply system 82 and the various components of the column 102 such as the heater 104 and the configuration of the housing 36.
  • the embodiments for the stationary phase supports 50 disclosed herein are suitable for separating chemical constituents of the mixture 1 10 that are highly aggressive such as when analyzing chemicals generated in the production of oil and natural gas, pharmaceuticals, or bio-chemicals.
  • the stationary phase support 50 is made from highly chemical resistant diamond and, thus, is capable of withstanding exposure to chemically aggressive solutions that have a pH less than about 5 or a pH greater than about 8 without significant chemical degradation.
  • highly acidic hydrofluoric acid may be used as the mobile phase 84.
  • sodium hydroxide may also be used either as a highly concentrated basic solution or in a pure liquid form as the mobile phase 84.
  • the stationary phase support 50 made from diamond is capable of withstanding temperatures in excess of 1000 0 C, which may be necessary for particular chemical analysis, separation processes, or reaction processes.
  • the stationary phase support 50 may be used for carrying out chemical reactions in highly aggressive chemical environments.
  • the stationary phase support 50 may be used for purifying specific chemicals such as, for example, at least one protein using highly aggressive solvents that may not be compatible with conventional stationary phases or stationary phase supports.
  • the chemical being purified is the sample 98 and the solvent is the mobile phase 84.
  • the mobile phase 84 i.e., the solvent
  • sample 98 i.e., at least one protein
  • the mobile phase 84 passes through the stationary phase support 50 and the purified at least one protein, the solvent, and the impurities of the protein flow through the outlet end 54 of the stationary phase support 50 at different rates where they captured, and further processed, chemically analyzed using the detector 108 as previously described, or both.
  • the body 60 comprised of porous polycrystalline diamond may be employed as a chemical reaction apparatus that does not necessarily effect separation of any chemical constituents.
  • at least one chemical constituent may be flowed into the body 60 that is maintained at a high temperature that effects cracking of the at least one chemical constituent.
  • highly aggressive chemical constituents may be flowed into the body 60 and a chemical reaction therebetween may take place within the passageways 62 of the body 60. Due to the body 60 being made from polycrystalline diamond that is very resistant to high temperature degradation and aggressive chemicals, the chemical reaction may involve highly aggressive chemical constituents and may take place at very high temperatures.
  • the high surface provided by the internal diamond surfaces of the passageways 62 may facilitate reaction between chemical constituents flowed into the passageways 62.
  • a suitable catalyst may be provided on the internal diamond surfaces of the passageways 62 to speed the reaction between chemical constituents flowed into the passageways 62.
  • FIG. 8 shows a separation device 120 that may be used for selectively separating at least one reaction product of a chemical reaction in accordance with another embodiment of the present invention.
  • the separation device 120 comprises a body 60' that includes a first portion 124 with an inlet end 52' and a second portion 126 with an outlet end 54'.
  • the first portion 124 includes pores/passageways 134 having a size that is greater than the size of pores/passageways 136 of the portion 126.
  • An inlet conduit 130 and a waste product conduit 132 are in fluid communication with the first portion 124 of the body 60'.
  • An optional, substantially non-porous diamond coating 64' may cover all portions of a peripheral surface 58' of the body 60' except the portions of the body 60' that are in fluid communication with the inlet conduit 130 and the waste product conduit 132.
  • the size of the pores/passageways 134 and 136 may be controlled during the fabrication process by proper selection of the diamond particle size and HPHT sintering conditions used to form the first and second portions 124 and 126 of the body 60'.
  • reagent A and B may flow at least one reagent A through the inlet end 52' of the body 60' and at least one reagent B through the inlet port 130.
  • a pump may pump the reagent A through a fluid line (not shown) and through the inlet end 52'
  • another pump may pump the reagent B through another fluid line (not shown) and through the inlet port 130.
  • the reagents A and B react with each other inside the pores/passageways 134 of the first portion 124 to form at least one reaction product P.
  • the reaction product P flows out of the outlet end 54' of the body 60', while waste product W, including any un-reacted reagents A and B and any other reaction waste product, flow out of the body 60' through the waste-product port 132.
  • the size of the pores/passageways 136 of the second portion 126 may be formed small enough so that substantially only the reaction P is capable of flowing through the second portion 126 and out of the outlet end 54', while the waste product W is large enough that it cannot flow through the second portion 126 and, thus, the waste product W flows out of the body 60' through the waste product conduit 132.

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  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Organic Chemistry (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)

Abstract

L'invention concerne un dispositif de séparation qui inclut un corps (50) de particules de diamant fritté. Le corps (50) inclut une extrémité d'entrée proximale (54), une extrémité de sortie distale(52) et une pluralité de pores interconnectés (62) s'étendant entre ces extrémités.
PCT/US2007/012879 2006-08-02 2007-05-31 Dispositif de séparation et appareil de réaction chimique fabriqués à partir de diamant polycristallin, appareils incluant ces dispositifs tels que des appareils de séparation, et procédés d'utilisation. Ceased WO2009008853A1 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP07809264A EP2035823B1 (fr) 2006-08-02 2007-05-31 Dispositif de séparation et appareil de réaction chimique fabriqués à partir de diamant polycristallin, appareils incluant ces dispositifs tels que des appareils de séparation, et procédés d'utilisation.
PCT/US2007/012879 WO2009008853A1 (fr) 2007-05-31 2007-05-31 Dispositif de séparation et appareil de réaction chimique fabriqués à partir de diamant polycristallin, appareils incluant ces dispositifs tels que des appareils de séparation, et procédés d'utilisation.
AT07809264T ATE547704T1 (de) 2006-08-02 2007-05-31 Abscheidungsvorrichtung und chemische reaktionsvorrichtung aus polykristallinem diamant,geräte wie etwa abscheidungsgeräte damit und verwendungsverfahren

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2007/012879 WO2009008853A1 (fr) 2007-05-31 2007-05-31 Dispositif de séparation et appareil de réaction chimique fabriqués à partir de diamant polycristallin, appareils incluant ces dispositifs tels que des appareils de séparation, et procédés d'utilisation.

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014182069A (ja) * 2013-03-21 2014-09-29 Kictec Inc 無機微粒子を含んだ汚染物からの無機微粒子の除去方法及び除去装置

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040121070A1 (en) * 2002-12-21 2004-06-24 Jishou Xu Connect diamond powders by cycloaddition reactions
US20060036106A1 (en) * 2004-08-12 2006-02-16 Terry Mazanec Process for converting ethylene to ethylene oxide using microchannel process technology

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040121070A1 (en) * 2002-12-21 2004-06-24 Jishou Xu Connect diamond powders by cycloaddition reactions
US20060036106A1 (en) * 2004-08-12 2006-02-16 Terry Mazanec Process for converting ethylene to ethylene oxide using microchannel process technology

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP2035823A4 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014182069A (ja) * 2013-03-21 2014-09-29 Kictec Inc 無機微粒子を含んだ汚染物からの無機微粒子の除去方法及び除去装置

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