WO2009025328A1 - アスコルビン酸誘導体又はその塩、その製造方法、及び化粧料 - Google Patents

アスコルビン酸誘導体又はその塩、その製造方法、及び化粧料 Download PDF

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Publication number
WO2009025328A1
WO2009025328A1 PCT/JP2008/064934 JP2008064934W WO2009025328A1 WO 2009025328 A1 WO2009025328 A1 WO 2009025328A1 JP 2008064934 W JP2008064934 W JP 2008064934W WO 2009025328 A1 WO2009025328 A1 WO 2009025328A1
Authority
WO
WIPO (PCT)
Prior art keywords
ascorbic acid
salt
acid derivative
producing
same
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2008/064934
Other languages
English (en)
French (fr)
Inventor
Masato Yoshioka
Norihisa Taira
Naoya Hashimoto
Akane Kamiyama
Keiichi Uehara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Seiwa Kasei Co Ltd
Original Assignee
Seiwa Kasei Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seiwa Kasei Co Ltd filed Critical Seiwa Kasei Co Ltd
Priority to US12/673,952 priority Critical patent/US8163939B2/en
Priority to CN2008801081441A priority patent/CN101801947B/zh
Priority to KR1020107005304A priority patent/KR101118600B1/ko
Priority to BRPI0816234-4A priority patent/BRPI0816234B1/pt
Priority to EP08828057A priority patent/EP2189452B1/en
Priority to JP2009529057A priority patent/JP4681670B2/ja
Priority to ES08828057T priority patent/ES2396798T3/es
Publication of WO2009025328A1 publication Critical patent/WO2009025328A1/ja
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/62—Three oxygen atoms, e.g. ascorbic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/676—Ascorbic acid, i.e. vitamin C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Nutrition Science (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Cosmetics (AREA)
  • Furan Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

　アスコルビン酸の２位又は３位の水酸基の水素の少なくとも一方が、Ｒ－Ｏ－ＣＨ２－ＣＨ（ＯＨ）－ＣＨ２－、Ｒ－Ｏ－ＣＨ２－ＣＨ（ＣＨ２ＯＨ）－、Ｒ－ＣＨ（ＣＨ２ＯＨ）－、Ｒ－ＣＨ（ＯＨ）－ＣＨ２－（Ｒは、アルキル基、アルケニニル基又はフェニル基）、又はヒドロキシシクロヘキシル基で置換されているアスコルビン酸誘導体又はその塩、並びにアスコルビン酸と、アルキルグリシジルエーテル、エポキシアルカン、脂環式エポキシ等のエポキシ化合物を反応させることを特徴とするその製造方法を提供する。
PCT/JP2008/064934 2007-08-22 2008-08-21 アスコルビン酸誘導体又はその塩、その製造方法、及び化粧料 Ceased WO2009025328A1 (ja)

Priority Applications (7)

Application Number Priority Date Filing Date Title
US12/673,952 US8163939B2 (en) 2007-08-22 2008-08-21 Ascorbic acid derivative or salt thereof, production method thereof, and cosmetic
CN2008801081441A CN101801947B (zh) 2007-08-22 2008-08-21 抗坏血酸衍生物或其盐，其制备方法，和化妆品
KR1020107005304A KR101118600B1 (ko) 2007-08-22 2008-08-21 아스코르브산 유도체 또는 그 염, 그 제조방법, 및 화장료
BRPI0816234-4A BRPI0816234B1 (pt) 2007-08-22 2008-08-21 Derivado de ácido ascórbico ou sal do mesmo, método de produção do mesmo, e cosmético
EP08828057A EP2189452B1 (en) 2007-08-22 2008-08-21 Ascorbic acid derivatives and salts thereof, process for their production, and cosmetic preparations thereof
JP2009529057A JP4681670B2 (ja) 2007-08-22 2008-08-21 アスコルビン酸誘導体又はその塩、その製造方法、及び化粧料
ES08828057T ES2396798T3 (es) 2007-08-22 2008-08-21 Derivados de ácido ascórbico y sales de los mismos, proceso para su producción y preparaciones cosméticas de los mismos

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2007-216446 2007-08-22
JP2007216446 2007-08-22
JP2007-216448 2007-08-22
JP2007216448 2007-08-22

Publications (1)

Publication Number Publication Date
WO2009025328A1 true WO2009025328A1 (ja) 2009-02-26

Family

ID=40378227

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/064934 Ceased WO2009025328A1 (ja) 2007-08-22 2008-08-21 アスコルビン酸誘導体又はその塩、その製造方法、及び化粧料

Country Status (8)

Country Link
US (1) US8163939B2 (ja)
EP (1) EP2189452B1 (ja)
JP (1) JP4681670B2 (ja)
KR (1) KR101118600B1 (ja)
CN (1) CN101801947B (ja)
BR (1) BRPI0816234B1 (ja)
ES (1) ES2396798T3 (ja)
WO (1) WO2009025328A1 (ja)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010189343A (ja) * 2009-02-19 2010-09-02 Seiwa Kasei Co Ltd グルコピラノシルアスコルビン酸誘導体又はその塩、その製造方法、及び化粧料
JP2011079772A (ja) * 2009-10-07 2011-04-21 Seiwa Kasei Co Ltd グリセリルアスコルビン酸アシル化誘導体又はその塩、その製造方法、及び化粧料。
WO2012023584A1 (ja) * 2010-08-19 2012-02-23 株式会社成和化成 アスコルビン酸由来組成物、その製造方法、及び化粧料
JP2014210711A (ja) * 2013-04-17 2014-11-13 日本精化株式会社 ヒアルロン酸産生促進剤
JP2015089876A (ja) * 2013-11-05 2015-05-11 株式会社ハーバー研究所 乳化化粧料及びその製造方法
JP2017057146A (ja) * 2015-09-14 2017-03-23 株式会社アイ・ティー・オー アンチプロオキシダント・グリセリルオクチルアスコルビン酸誘導体その製法及び用途
JP2019064990A (ja) * 2017-10-05 2019-04-25 ピアス株式会社 ＲｈｏＧＤＩβ抑制剤及び化粧料
JP2024034984A (ja) * 2022-08-30 2024-03-13 株式会社ピカソ美化学研究所 皮膚用乳化組成物
WO2024111142A1 (ja) * 2022-11-25 2024-05-30 株式会社成和化成 アスコルビン酸誘導体又はその塩及びその化粧料
JP7685175B1 (ja) * 2023-11-28 2025-05-29 株式会社成和化成 アスコルビン酸誘導体及びそれらを配合した化粧料
US12521335B2 (en) 2021-05-20 2026-01-13 Roc Opco Llc Cosmetic compositions containing vitamin C compounds and uses thereof

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115260170B (zh) * 2021-04-30 2024-05-28 禾美生物科技(浙江)有限公司 抗坏血酸多肽衍生物及其制备方法和应用
CN116410346A (zh) * 2021-12-31 2023-07-11 华熙生物科技股份有限公司 一种还原性透明质酸酯及其制备方法
JP7267657B1 (ja) 2022-11-25 2023-05-02 株式会社成和化成 アスコルビン酸誘導体又はその塩及びその化粧料
CN117658963B (zh) * 2023-12-01 2025-10-10 上海克琴科技有限公司 一种维生素c衍生物的非对映异构体及其制备和应用

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JPH04149117A (ja) * 1990-10-12 1992-05-22 Kanebo Ltd 美白化粧料
JP2002265459A (ja) * 2001-02-23 2002-09-18 Basf Ag 結晶性アスコルビン酸コリン
JP2005239645A (ja) * 2004-02-27 2005-09-08 Rohto Pharmaceut Co Ltd コラーゲン合成促進用組成物

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JPS60130582A (ja) * 1983-12-19 1985-07-12 Takeda Chem Ind Ltd 食品用酸化防止剤，アスコルビン酸誘導体およびその製造法
JP3112341B2 (ja) * 1992-06-01 2000-11-27 関東電化工業株式会社 ビタミンｃ及びビタミンｅを含む結合体ならびに製造方法
JP3440263B2 (ja) * 1998-03-27 2003-08-25 エルジー・ライフ・サイエンシーズ・リミテッド 新規アスコルビン酸誘導体及びその調製方法
JP2003119120A (ja) 2001-10-12 2003-04-23 Masahiko Abe リポソームの製造方法、及び該リポソームを含有する化粧料、及び皮膚外用剤
EP1527777A1 (de) * 2003-10-31 2005-05-04 MERCK PATENT GmbH Zubereitung mit antioxidanten Eigenschaften, die einen Benzoesäureester der Ascorbinsäure enthält
JP2006001866A (ja) 2004-06-16 2006-01-05 Nikko Chemical Co Ltd メラニン産生抑制剤
JP4228230B2 (ja) 2004-11-08 2009-02-25 独立行政法人産業技術総合研究所 リポソーム懸濁液の製造方法及びリポソームを用いた用途

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04149117A (ja) * 1990-10-12 1992-05-22 Kanebo Ltd 美白化粧料
JP2002265459A (ja) * 2001-02-23 2002-09-18 Basf Ag 結晶性アスコルビン酸コリン
JP2005239645A (ja) * 2004-02-27 2005-09-08 Rohto Pharmaceut Co Ltd コラーゲン合成促進用組成物

Non-Patent Citations (3)

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Title
MORISAKI, KAZUO ET AL.: "Design of novel hybrid vitamin C derivatives: thermal stability and biological activity", CHEMICAL & PHARMACEUTICAL BULLETIN, vol. 44, no. 9, September 1996 (1996-09-01), pages 1647 - 1655, XP001026205 *
See also references of EP2189452A4 *
VOISIN-CHIRET, ANNE SOPHIE ET AL.: "Synthesis of new L-ascorbic ferulic acid hybrids", MOLECULES, vol. 12, no. 11, November 2007 (2007-11-01), pages 2533 - 2545, XP008131364, DOI: doi:10.3390/12112533 *

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010189343A (ja) * 2009-02-19 2010-09-02 Seiwa Kasei Co Ltd グルコピラノシルアスコルビン酸誘導体又はその塩、その製造方法、及び化粧料
JP2011079772A (ja) * 2009-10-07 2011-04-21 Seiwa Kasei Co Ltd グリセリルアスコルビン酸アシル化誘導体又はその塩、その製造方法、及び化粧料。
WO2012023584A1 (ja) * 2010-08-19 2012-02-23 株式会社成和化成 アスコルビン酸由来組成物、その製造方法、及び化粧料
JP2014210711A (ja) * 2013-04-17 2014-11-13 日本精化株式会社 ヒアルロン酸産生促進剤
JP2015089876A (ja) * 2013-11-05 2015-05-11 株式会社ハーバー研究所 乳化化粧料及びその製造方法
JP2017057146A (ja) * 2015-09-14 2017-03-23 株式会社アイ・ティー・オー アンチプロオキシダント・グリセリルオクチルアスコルビン酸誘導体その製法及び用途
JP2019064990A (ja) * 2017-10-05 2019-04-25 ピアス株式会社 ＲｈｏＧＤＩβ抑制剤及び化粧料
JP7084595B2 (ja) 2017-10-05 2022-06-15 ピアス株式会社 ＲｈｏＧＤＩβ抑制剤
US12521335B2 (en) 2021-05-20 2026-01-13 Roc Opco Llc Cosmetic compositions containing vitamin C compounds and uses thereof
JP2024034984A (ja) * 2022-08-30 2024-03-13 株式会社ピカソ美化学研究所 皮膚用乳化組成物
WO2024111142A1 (ja) * 2022-11-25 2024-05-30 株式会社成和化成 アスコルビン酸誘導体又はその塩及びその化粧料
JP7685175B1 (ja) * 2023-11-28 2025-05-29 株式会社成和化成 アスコルビン酸誘導体及びそれらを配合した化粧料
WO2025115272A1 (ja) * 2023-11-28 2025-06-05 株式会社成和化成 アスコルビン酸誘導体及びそれらを配合した化粧料

Also Published As

Publication number Publication date
JPWO2009025328A1 (ja) 2010-11-25
EP2189452B1 (en) 2012-11-21
EP2189452A4 (en) 2011-05-25
BRPI0816234B1 (pt) 2018-01-23
US8163939B2 (en) 2012-04-24
CN101801947B (zh) 2012-11-21
CN101801947A (zh) 2010-08-11
KR20100056498A (ko) 2010-05-27
KR101118600B1 (ko) 2012-04-12
BRPI0816234A2 (pt) 2015-02-24
ES2396798T3 (es) 2013-02-27
US20110059034A1 (en) 2011-03-10
EP2189452A1 (en) 2010-05-26
JP4681670B2 (ja) 2011-05-11

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