WO2009030205A3 - Nouveaux conjugués gélatine-agent actif - Google Patents

Nouveaux conjugués gélatine-agent actif Download PDF

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Publication number
WO2009030205A3
WO2009030205A3 PCT/DE2008/001452 DE2008001452W WO2009030205A3 WO 2009030205 A3 WO2009030205 A3 WO 2009030205A3 DE 2008001452 W DE2008001452 W DE 2008001452W WO 2009030205 A3 WO2009030205 A3 WO 2009030205A3
Authority
WO
WIPO (PCT)
Prior art keywords
gelatine
active ingredient
ingredient conjugates
conjugates
conjugate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/DE2008/001452
Other languages
German (de)
English (en)
Other versions
WO2009030205A2 (fr
Inventor
Hannsjörg SINN
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of WO2009030205A2 publication Critical patent/WO2009030205A2/fr
Publication of WO2009030205A3 publication Critical patent/WO2009030205A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/65Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/6435Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the peptide or protein in the drug conjugate being a connective tissue peptide, e.g. collagen, fibronectin or gelatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/57Compounds covalently linked to a(n inert) carrier molecule, e.g. conjugates, pro-fragrances

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)

Abstract

L'invention concerne une composition pharmaceutique et/ou cosmétique contenant un conjugué composé d'un agent actif naturel ou synthétique comportant un ou plusieurs groupes réactifs, et de gélatine.
PCT/DE2008/001452 2007-09-03 2008-09-03 Nouveaux conjugués gélatine-agent actif Ceased WO2009030205A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102007041625A DE102007041625A1 (de) 2007-09-03 2007-09-03 Neue Gelatine-Wirkstoff-Konjugate
DE102007041625.5 2007-09-03

Publications (2)

Publication Number Publication Date
WO2009030205A2 WO2009030205A2 (fr) 2009-03-12
WO2009030205A3 true WO2009030205A3 (fr) 2010-02-25

Family

ID=40299099

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DE2008/001452 Ceased WO2009030205A2 (fr) 2007-09-03 2008-09-03 Nouveaux conjugués gélatine-agent actif

Country Status (2)

Country Link
DE (1) DE102007041625A1 (fr)
WO (1) WO2009030205A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011100984A1 (fr) * 2010-02-17 2011-08-25 El-Sayed Ameen Mahmoud Rezq Gélatine en tant que système de véhicule de médicament de curcumine

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0240581A1 (fr) * 1986-04-05 1987-10-14 R.P. Scherer GmbH Capsules de gélatine à libération contrôlée de la substance active et procédé pour leur préparation
JP2004196705A (ja) * 2002-12-18 2004-07-15 Kyowa Chem Ind Co Ltd パップ剤
EP1500664A1 (fr) * 2002-04-26 2005-01-26 Yasuhiko Tabata Derives de gelatine et micelles a poids moleculaire eleve les contenant
DE102004041340A1 (de) * 2004-08-20 2006-02-23 Deutsche Gelatine-Fabriken Stoess Ag Nanopartikel und Verfahren zu deren Herstellung

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5298243A (en) * 1988-10-20 1994-03-29 Denki Kagaku Kogyo Kabushiki Kaisha Colony stimulating factor-gelatin conjugate
DE10112982A1 (de) * 2001-03-17 2002-09-19 Abb Research Ltd Verfahren und Regelanordnung zum Betrieb eines dreiphasigen Hochsetzstellers mit Leistungsfaktorkorrektur
US10092662B2 (en) * 2004-03-31 2018-10-09 University Of Utah Research Foundation Macromolecular delivery systems for non-invasive imaging, evaluation and treatment of arthritis and other inflammatory diseases

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0240581A1 (fr) * 1986-04-05 1987-10-14 R.P. Scherer GmbH Capsules de gélatine à libération contrôlée de la substance active et procédé pour leur préparation
EP1500664A1 (fr) * 2002-04-26 2005-01-26 Yasuhiko Tabata Derives de gelatine et micelles a poids moleculaire eleve les contenant
JP2004196705A (ja) * 2002-12-18 2004-07-15 Kyowa Chem Ind Co Ltd パップ剤
DE102004041340A1 (de) * 2004-08-20 2006-02-23 Deutsche Gelatine-Fabriken Stoess Ag Nanopartikel und Verfahren zu deren Herstellung

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
BOWMAN BILL J ET AL: "Characterization and in vitro methotrexate release from methotrexate/gelatin conjugates of opposite conjugate bond polarity", PHARMACEUTICAL RESEARCH (NEW YORK), vol. 17, no. 10, October 2000 (2000-10-01), pages 1309 - 1315, XP002543455, ISSN: 0724-8741 *
CHANG C P ET AL: "Release properties on gelatin-gum arabic microcapsules containing camphor oil with added polystyrene", COLLOIDS AND SURFACES. B, BIOINTERFACES, ELSEVIER, AMSTERDAM, NL, vol. 50, no. 2, 1 July 2006 (2006-07-01), pages 136 - 140, XP025137017, ISSN: 0927-7765, [retrieved on 20060701] *
DI SILVIO L ET AL: "The use of gelatin as a vehicle for drug and peptide delivery", JOURNAL OF MATERIALS SCIENCE: MATERIALS IN MEDICINE 199411 GB, vol. 5, no. 11, November 1994 (1994-11-01), pages 819 - 823, XP002543453, ISSN: 0957-4530 *
KOMMAREDDY S ET AL: "Preparation and evaluation of thiol-modified gelatin nanoparticles for intracellular DNA delivery in response to glutathione", BIOCONJUGATE CHEMISTRY 200511 US, vol. 16, no. 6, November 2005 (2005-11-01), pages 1423 - 1432, XP002543454, ISSN: 1043-1802 *
LEO ELIANA ET AL: "Doxorubicin-loaded gelatin nanoparticles stabilized by glutaraldehyde: Involvement of the drug in the cross-linking process", INTERNATIONAL JOURNAL OF PHARMACEUTICS (AMSTERDAM), vol. 155, no. 1, 1997, pages 75 - 82, XP002543531, ISSN: 0378-5173 *
PICA KAREN ET AL: "Gelatin-methotrexate conjugate microspheres as a potential drug delivery system", JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 95, no. 9, September 2006 (2006-09-01), pages 1896 - 1908, XP002543456, ISSN: 0022-3549 *
YOUNG ET AL: "Gelatin as a delivery vehicle for the controlled release of bioactive molecules", JOURNAL OF CONTROLLED RELEASE, ELSEVIER, AMSTERDAM, NL, vol. 109, no. 1-3, 5 December 2005 (2005-12-05), pages 256 - 274, XP005204218, ISSN: 0168-3659 *

Also Published As

Publication number Publication date
WO2009030205A2 (fr) 2009-03-12
DE102007041625A1 (de) 2009-03-05

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