WO2009069504A1 - タンパク吸着材料およびその製造方法 - Google Patents

タンパク吸着材料およびその製造方法 Download PDF

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Publication number
WO2009069504A1
WO2009069504A1 PCT/JP2008/070923 JP2008070923W WO2009069504A1 WO 2009069504 A1 WO2009069504 A1 WO 2009069504A1 JP 2008070923 W JP2008070923 W JP 2008070923W WO 2009069504 A1 WO2009069504 A1 WO 2009069504A1
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WO
WIPO (PCT)
Prior art keywords
producing
protein adsorbent
protein
polymer
side chain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2008/070923
Other languages
English (en)
French (fr)
Inventor
Goro Furumoto
Noboru Kubota
Kyoichi Saito
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asahi Kasei Chemicals Corp
Original Assignee
Asahi Kasei Chemicals Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asahi Kasei Chemicals Corp filed Critical Asahi Kasei Chemicals Corp
Priority to US12/744,066 priority Critical patent/US8536288B2/en
Priority to EP08855723A priority patent/EP2221103B1/en
Priority to KR1020107003387A priority patent/KR101161072B1/ko
Priority to CA2706611A priority patent/CA2706611C/en
Priority to AU2008330807A priority patent/AU2008330807B2/en
Priority to CN200880111804A priority patent/CN101827648A/zh
Priority to JP2009543761A priority patent/JP4699556B2/ja
Publication of WO2009069504A1 publication Critical patent/WO2009069504A1/ja
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J7/00—Chemical treatment or coating of shaped articles made of macromolecular substances
    • C08J7/12—Chemical modification
    • C08J7/16—Chemical modification with polymerisable compounds
    • C08J7/18—Chemical modification with polymerisable compounds using wave energy or particle radiation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B01J20/261—Synthetic macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B01J20/264—Synthetic macromolecular compounds derived from different types of monomers, e.g. linear or branched copolymers, block copolymers, graft copolymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B01J20/265—Synthetic macromolecular compounds modified or post-treated polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3206—Organic carriers, supports or substrates
    • B01J20/3208—Polymeric carriers, supports or substrates
    • B01J20/321—Polymeric carriers, supports or substrates consisting of a polymer obtained by reactions involving only carbon to carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/3278—Polymers being grafted on the carrier
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B01J20/328—Polymers on the carrier being further modified
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2323/00—Characterised by the use of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Derivatives of such polymers
    • C08J2323/02—Characterised by the use of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Derivatives of such polymers not modified by chemical after treatment
    • C08J2323/04—Homopolymers or copolymers of ethene

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Treatments Of Macromolecular Shaped Articles (AREA)
  • Graft Or Block Polymers (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Peptides Or Proteins (AREA)

Abstract

　分析用途はもちろんのこと、工業生産用としても適用可能な程度の吸着容量と高速処理性とを両立するタンパク吸着材料及びその製造方法を提供することを目的とする。本発明は、高分子基材と、その高分子基材の表面に固定された高分子側鎖と、その高分子側鎖に固定されたタンパク質吸着能を有する官能基と、を含有し、前記高分子側鎖の質量が前記高分子基材の質量に対して５～３０％であるタンパク吸着材料を提供する。
PCT/JP2008/070923 2007-11-26 2008-11-18 タンパク吸着材料およびその製造方法 Ceased WO2009069504A1 (ja)

Priority Applications (7)

Application Number Priority Date Filing Date Title
US12/744,066 US8536288B2 (en) 2007-11-26 2008-11-18 Protein-adsorbing material and method for producing the same
EP08855723A EP2221103B1 (en) 2007-11-26 2008-11-18 Protein adsorbent and method for producing the same
KR1020107003387A KR101161072B1 (ko) 2007-11-26 2008-11-18 단백 흡착 재료 및 그 제조 방법
CA2706611A CA2706611C (en) 2007-11-26 2008-11-18 Protein-adsorbing material and method for producing the same
AU2008330807A AU2008330807B2 (en) 2007-11-26 2008-11-18 Protein-adsorbing material and method for producing the same
CN200880111804A CN101827648A (zh) 2007-11-26 2008-11-18 蛋白吸附材料及其制造方法
JP2009543761A JP4699556B2 (ja) 2007-11-26 2008-11-18 タンパク吸着材料およびその製造方法

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-304826 2007-11-26
JP2007304826A JP2011016036A (ja) 2007-11-26 2007-11-26 タンパク吸着材料およびその製造方法

Publications (1)

Publication Number Publication Date
WO2009069504A1 true WO2009069504A1 (ja) 2009-06-04

Family

ID=40678406

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Application Number Title Priority Date Filing Date
PCT/JP2008/070923 Ceased WO2009069504A1 (ja) 2007-11-26 2008-11-18 タンパク吸着材料およびその製造方法

Country Status (9)

Country Link
US (1) US8536288B2 (ja)
EP (1) EP2221103B1 (ja)
JP (2) JP2011016036A (ja)
KR (1) KR101161072B1 (ja)
CN (1) CN101827648A (ja)
AU (1) AU2008330807B2 (ja)
CA (1) CA2706611C (ja)
TW (1) TW200936238A (ja)
WO (1) WO2009069504A1 (ja)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101997543B1 (ko) 2010-07-30 2019-07-09 이엠디 밀리포어 코포레이션 크로마토그래피 매질 및 방법
JP2013006942A (ja) * 2011-06-23 2013-01-10 Nhv Corporation 吸着性ポリマーおよびその製造方法
JP5940788B2 (ja) * 2011-09-28 2016-06-29 旭化成株式会社 選択的分離材及びその製造方法、並びに血液処理器
US9545627B2 (en) 2011-12-15 2017-01-17 Asahi Kasei Chemicals Corporation Protein adsorbent
JP6147162B2 (ja) * 2012-10-30 2017-06-14 株式会社クラレ エチレン−ビニルアルコール系共重合体のグラフト共重合体、その製造方法及びそれを用いた金属イオン吸着材
WO2014069474A1 (ja) 2012-10-30 2014-05-08 株式会社クラレ 多孔質グラフト共重合体粒子、その製造方法及びそれを用いた吸着材
JP6444579B2 (ja) * 2012-11-07 2018-12-26 フマキラー株式会社 薬剤収容具
ES2877563T3 (es) 2014-09-02 2021-11-17 Emd Millipore Corp Medios de cromotografía que comprenden conjuntos porosos discretos de nanofibrillas
US20170298091A1 (en) 2014-12-08 2017-10-19 Emd Millipore Corporation Mixed Bed Ion Exchange Adsorber
JP6901252B2 (ja) * 2015-10-21 2021-07-14 株式会社日本触媒 接着性細胞培養用基材、ならびにこれを利用した細胞培養容器および細胞培養方法
JP2018040772A (ja) * 2016-09-09 2018-03-15 旭化成メディカル株式会社 イオン交換クロマトグラフィー担体

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02203933A (ja) * 1989-01-30 1990-08-13 Japan Atom Energy Res Inst 染料を有するアフィニティ吸着剤の製造方法
JPH09299477A (ja) * 1996-05-14 1997-11-25 Toyobo Co Ltd コレステロール吸着材、コレステロール除去フィルター、およびコレステロール除去方法
JP2006026588A (ja) * 2004-07-20 2006-02-02 Japan Atom Energy Res Inst 温泉水に溶存する有用・有害金属を回収および除去する方法
JP2007159874A (ja) * 2005-12-15 2007-06-28 Asahi Kasei Corp リガンド固定化用基材および細胞選択吸着材

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FR2534486B1 (fr) 1982-10-15 1987-11-20 Commissariat Energie Atomique Support particulaire greffe en surface, son procede de preparation et adsorbants pour chromatographie d'affinite incorporant ce support, ainsi que leur utilisation, notamment en biologie
CA1223856A (en) 1983-09-28 1987-07-07 Brent J. Bertus Passivation of metal contaminants on cracking catalysts
CA1314666C (en) * 1988-06-13 1993-03-23 Kazuo Toyomoto Selectively ion-adsorptive, porous membrane
DK72493D0 (da) * 1993-06-18 1993-06-18 Risoe Forskningscenter Solid supports for use in peptide synthesis and assays
EP1095967A1 (fr) 1999-10-29 2001-05-02 Computer Cell Culture Center S.A. Nouveaux supports de culture cellulaire porteurs de propriétés particulières et leur production
DE10149256A1 (de) * 2001-10-05 2003-04-17 Merck Patent Gmbh Alkalistabile hydrophile Sorbentien für die Ionenaustauschchromatographie
JP2005510609A (ja) * 2001-11-26 2005-04-21 アメルシャム・バイオサイエンシーズ・アクチボラグ 多孔性支持体の後修飾
WO2004026931A2 (en) * 2002-09-18 2004-04-01 Emembrane, Inc. Functionalized materials and methods of using same
JP2008540761A (ja) * 2005-05-13 2008-11-20 プロティスタ バイオテクノロジー アーベー マクロ多孔性ハイドロゲル、その調製法及びその使用

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02203933A (ja) * 1989-01-30 1990-08-13 Japan Atom Energy Res Inst 染料を有するアフィニティ吸着剤の製造方法
JPH09299477A (ja) * 1996-05-14 1997-11-25 Toyobo Co Ltd コレステロール吸着材、コレステロール除去フィルター、およびコレステロール除去方法
JP2006026588A (ja) * 2004-07-20 2006-02-02 Japan Atom Energy Res Inst 温泉水に溶存する有用・有害金属を回収および除去する方法
JP2007159874A (ja) * 2005-12-15 2007-06-28 Asahi Kasei Corp リガンド固定化用基材および細胞選択吸着材

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
KYOICHI SAITO ET AL., CHEMICAL ENGINEERING, August 1996 (1996-08-01), pages 25 - 28
NOBORU KUBOTA, RADIATION AND INDUSTRY, vol. 80, December 1998 (1998-12-01), pages 45 - 47
See also references of EP2221103A4 *

Also Published As

Publication number Publication date
EP2221103A4 (en) 2011-06-29
CA2706611A1 (en) 2009-06-04
TW200936238A (en) 2009-09-01
CN101827648A (zh) 2010-09-08
US8536288B2 (en) 2013-09-17
EP2221103A1 (en) 2010-08-25
JP4699556B2 (ja) 2011-06-15
TWI376265B (ja) 2012-11-11
JPWO2009069504A1 (ja) 2011-04-14
AU2008330807B2 (en) 2012-02-02
JP2011016036A (ja) 2011-01-27
EP2221103B1 (en) 2013-04-03
KR101161072B1 (ko) 2012-06-29
AU2008330807A1 (en) 2009-06-04
KR20100034043A (ko) 2010-03-31
US20100248954A1 (en) 2010-09-30
CA2706611C (en) 2013-04-23

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