WO2009072332A1 - Réacteur et procédé de traitement de réaction - Google Patents

Réacteur et procédé de traitement de réaction Download PDF

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Publication number
WO2009072332A1
WO2009072332A1 PCT/JP2008/065843 JP2008065843W WO2009072332A1 WO 2009072332 A1 WO2009072332 A1 WO 2009072332A1 JP 2008065843 W JP2008065843 W JP 2008065843W WO 2009072332 A1 WO2009072332 A1 WO 2009072332A1
Authority
WO
WIPO (PCT)
Prior art keywords
sample
reactor
channel
treatment method
reaction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2008/065843
Other languages
English (en)
Japanese (ja)
Inventor
Nobuhiro Hanafusa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shimadzu Corp
Original Assignee
Shimadzu Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shimadzu Corp filed Critical Shimadzu Corp
Priority to JP2009544603A priority Critical patent/JP4883188B2/ja
Publication of WO2009072332A1 publication Critical patent/WO2009072332A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/04—Exchange or ejection of cartridges, containers or reservoirs
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0642—Filling fluids into wells by specific techniques
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0684—Venting, avoiding backpressure, avoid gas bubbles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0689—Sealing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/16—Reagents, handling or storing thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/041—Connecting closures to device or container
    • B01L2300/044—Connecting closures to device or container pierceable, e.g. films, membranes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/046—Function or devices integrated in the closure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0829—Multi-well plates; Microtitration plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0864—Configuration of multiple channels and/or chambers in a single devices comprising only one inlet and multiple receiving wells, e.g. for separation, splitting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0478—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure pistons
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0622—Valves, specific forms thereof distribution valves, valves having multiple inlets and/or outlets, e.g. metering valves, multi-way valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0633—Valves, specific forms thereof with moving parts
    • B01L2400/0644—Valves, specific forms thereof with moving parts rotary valves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0677—Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers
    • B01L2400/0683—Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers mechanically breaking a wall or membrane within a channel or chamber
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1079—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices with means for piercing stoppers or septums
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1095—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers
    • G01N35/1097—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers characterised by the valves

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)

Abstract

L'invention a pour objectif de prévenir l'invasion de matières étrangères dans un réacteur ou une pollution environnementale à l'extérieur du réacteur. À cet effet, l'invention porte sur un réacteur (1) qui comprend une chambre de réaction fermée (5) dans laquelle un échantillon est amené à réagir ; des canaux de réaction (13, 15, 17) reliés à la chambre de réaction (5) ; un contenant pour échantillons (35) comportant une section destinée à contenir un échantillon (35g) dans laquelle est renfermé l'échantillon, un canal pour échantillons (35a) relié à la section destinée à contenir l'échantillon (35g) lors de l'utilisation du contenant pour échantillons (35), une seringue (51) pour alimenter un liquide et une soupape de commutation (63) pour relier la seringue (51) à un canal de réaction (13) ou au canal pour échantillons (35a).
PCT/JP2008/065843 2007-12-04 2008-09-03 Réacteur et procédé de traitement de réaction Ceased WO2009072332A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2009544603A JP4883188B2 (ja) 2007-12-04 2008-09-03 反応容器及び反応処理方法

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-313496 2007-12-04
JP2007313496 2007-12-04

Publications (1)

Publication Number Publication Date
WO2009072332A1 true WO2009072332A1 (fr) 2009-06-11

Family

ID=40717514

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/065843 Ceased WO2009072332A1 (fr) 2007-12-04 2008-09-03 Réacteur et procédé de traitement de réaction

Country Status (2)

Country Link
JP (1) JP4883188B2 (fr)
WO (1) WO2009072332A1 (fr)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011161894A1 (fr) * 2010-06-22 2011-12-29 コニカミノルタホールディングス株式会社 Dispositif distributeur de liquide et puce d'essai l'utilisant
JP2014182134A (ja) * 2013-03-15 2014-09-29 Ortho-Clinical Diagnostics Inc 回転可能なディスク状の流体サンプル採取デバイス
JP2017500010A (ja) * 2013-10-28 2017-01-05 ビオカルティ ナームローゼ フェノーツハップＢｉｏｃａｒｔｉｓ ＮＶ 生体材料の搬送装置
CN108753589A (zh) * 2018-06-07 2018-11-06 北京金诺美生物技术有限公司 一种用于实时荧光定量pcr检测的样品杯
WO2020158712A1 (fr) * 2019-02-01 2020-08-06 株式会社エンプラス Système et cartouche de manipulation de fluide
US11878301B2 (en) 2021-06-07 2024-01-23 Credo Diagnostics Biomedical Pte. Ltd. Analysis cartridge
JP2025507221A (ja) * 2022-03-08 2025-03-13 ユージーンセル インコーポレイテッド 検体検査装置及び検体検査方法

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU102877B1 (en) 2021-11-12 2023-05-17 STRATEC CONSUMABLES GmbH System for providing fluids in microfluidic products

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004325462A (ja) * 2004-08-09 2004-11-18 Hitachi Ltd 化学分析装置と化学分析システム
JP2005502031A (ja) * 2001-08-28 2005-01-20 ユィロス・アクチボラグ 保持するためのマイクロ流体マイクロキャビティおよび他のマイクロ流体構造体
JP2006017719A (ja) * 2004-06-30 2006-01-19 Lifescan Scotland Ltd 流れ経路中の流れの調整方法
JP2006234590A (ja) * 2005-02-25 2006-09-07 Shimadzu Corp 反応容器
JP2006308366A (ja) * 2005-04-27 2006-11-09 Hitachi High-Technologies Corp 化学分析装置及び化学分析カートリッジ
JP2007502435A (ja) * 2003-05-30 2007-02-08 アプレラ コーポレイション ハイブリダイゼーションおよびｓｐｒ検出のための装置および方法

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005502031A (ja) * 2001-08-28 2005-01-20 ユィロス・アクチボラグ 保持するためのマイクロ流体マイクロキャビティおよび他のマイクロ流体構造体
JP2007502435A (ja) * 2003-05-30 2007-02-08 アプレラ コーポレイション ハイブリダイゼーションおよびｓｐｒ検出のための装置および方法
JP2006017719A (ja) * 2004-06-30 2006-01-19 Lifescan Scotland Ltd 流れ経路中の流れの調整方法
JP2004325462A (ja) * 2004-08-09 2004-11-18 Hitachi Ltd 化学分析装置と化学分析システム
JP2006234590A (ja) * 2005-02-25 2006-09-07 Shimadzu Corp 反応容器
JP2006308366A (ja) * 2005-04-27 2006-11-09 Hitachi High-Technologies Corp 化学分析装置及び化学分析カートリッジ

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011161894A1 (fr) * 2010-06-22 2011-12-29 コニカミノルタホールディングス株式会社 Dispositif distributeur de liquide et puce d'essai l'utilisant
JP5849950B2 (ja) * 2010-06-22 2016-02-03 コニカミノルタ株式会社 送液装置
JP2014182134A (ja) * 2013-03-15 2014-09-29 Ortho-Clinical Diagnostics Inc 回転可能なディスク状の流体サンプル採取デバイス
US11026611B2 (en) 2013-03-15 2021-06-08 Ortho-Clinical Diagnostics, Inc. Rotatable disk-shaped fluid sample collection device
JP2017500010A (ja) * 2013-10-28 2017-01-05 ビオカルティ ナームローゼ フェノーツハップＢｉｏｃａｒｔｉｓ ＮＶ 生体材料の搬送装置
US10279343B2 (en) 2013-10-28 2019-05-07 Biocartis Nv Transfer device of biological material
CN108753589A (zh) * 2018-06-07 2018-11-06 北京金诺美生物技术有限公司 一种用于实时荧光定量pcr检测的样品杯
CN108753589B (zh) * 2018-06-07 2024-03-19 北京金诺美科技股份有限公司 一种用于实时荧光定量pcr检测的样品杯
WO2020158712A1 (fr) * 2019-02-01 2020-08-06 株式会社エンプラス Système et cartouche de manipulation de fluide
US11878301B2 (en) 2021-06-07 2024-01-23 Credo Diagnostics Biomedical Pte. Ltd. Analysis cartridge
JP2025507221A (ja) * 2022-03-08 2025-03-13 ユージーンセル インコーポレイテッド 検体検査装置及び検体検査方法
JP7834895B2 (ja) 2022-03-08 2026-03-24 ユージーンセル インコーポレイテッド 検体検査装置及び検体検査方法

Also Published As

Publication number Publication date
JP4883188B2 (ja) 2012-02-22
JPWO2009072332A1 (ja) 2011-04-21

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