WO2009083263A3 - Transport-, weitergabe- und/oder wirksystem in aseptischer darreichung - Google Patents

Transport-, weitergabe- und/oder wirksystem in aseptischer darreichung Download PDF

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Publication number
WO2009083263A3
WO2009083263A3 PCT/EP2008/011155 EP2008011155W WO2009083263A3 WO 2009083263 A3 WO2009083263 A3 WO 2009083263A3 EP 2008011155 W EP2008011155 W EP 2008011155W WO 2009083263 A3 WO2009083263 A3 WO 2009083263A3
Authority
WO
WIPO (PCT)
Prior art keywords
transport
distribution
effective system
collagen
configuring
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2008/011155
Other languages
English (en)
French (fr)
Other versions
WO2009083263A2 (de
Inventor
Arne Briest
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ossacur AG
Original Assignee
Ossacur AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ossacur AG filed Critical Ossacur AG
Publication of WO2009083263A2 publication Critical patent/WO2009083263A2/de
Publication of WO2009083263A3 publication Critical patent/WO2009083263A3/de
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56Porous materials, e.g. foams or sponges
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0028Polypeptides; Proteins; Degradation products thereof
    • A61L26/0033Collagen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061Use of materials characterised by their function or physical properties
    • A61L26/0066Medicaments; Biocides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061Use of materials characterised by their function or physical properties
    • A61L26/0085Porous materials, e.g. foams or sponges
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061Use of materials characterised by their function or physical properties
    • A61L26/009Materials resorbable by the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/22Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24Collagen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58Materials at least partially resorbable by the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404Biocides, antimicrobial agents, antiseptic agents
    • A61L2300/406Antibiotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412Tissue-regenerating or healing or proliferative agents
    • A61L2300/414Growth factors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/45Mixtures of two or more drugs, e.g. synergistic mixtures

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Materials Engineering (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dispersion Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Laminated Bodies (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Die Erfindung betrifft ein zumindest teilweise bioresorbierbares Transport-, Weitergabe- und/oder Wirksystem mit einer Schicht- oder Sandwichstruktur, das einen Vliesstoff als Gerüststoff aufweist, in den Kollagen zur Ausbildung der Schicht eingebaut und/oder an den Kollagen zur Ausbildung der Sandwichstruktur angelagert ist. Zumindest eine der Oberflächen des Transport-, Weitergabe- und/oder Wirksystems weist eine im wesentlichen poröse Oberfläche auf. Es kann zusätzlich ein Arzneimittel enthalten sein. Außerdem kann das System zumindest einen osteoinduktiven oder chondroinduktiven Wirkstoff aufweisen, wie z.B. einen der Differenzierungs- und/oder Wachstumsfaktoren der TGF ß -Superfamilie. Der Vliesstoff weist Fasern auf, die ausgewählt sind aus Zellulosefasern, wie Viskose, Polyester, Polyacrylnitril, gegebenenfalls in Kombination mit einem Superabsorber. Die Erfindung betrifft auch ein Verfahren zur Herstellung des Systems sowie das System als aseptische Darreichung. Dabei befindet sich das System in einem Behälter, der mittels eines Kunststofffolienformteils in Form einer membranartigen Folie als Sterilbarriere abgeschlossen ist.
PCT/EP2008/011155 2007-12-31 2008-12-31 Transport-, weitergabe- und/oder wirksystem in aseptischer darreichung Ceased WO2009083263A2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE200710063395 DE102007063395A1 (de) 2007-12-31 2007-12-31 Transport-, Weitergabe- und/oder Wirksystem in aseptischer Darreichung
DE102007063395.7 2007-12-31

Publications (2)

Publication Number Publication Date
WO2009083263A2 WO2009083263A2 (de) 2009-07-09
WO2009083263A3 true WO2009083263A3 (de) 2010-05-27

Family

ID=40640228

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2008/011155 Ceased WO2009083263A2 (de) 2007-12-31 2008-12-31 Transport-, weitergabe- und/oder wirksystem in aseptischer darreichung

Country Status (2)

Country Link
DE (1) DE102007063395A1 (de)
WO (1) WO2009083263A2 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102022119473A1 (de) 2022-08-03 2024-02-08 Universität Rostock, Körperschaft des öffentlichen Rechts Faservliesstoff und Verfahren zur Herstellung eines Faservliesstoffes

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040126405A1 (en) * 2002-12-30 2004-07-01 Scimed Life Systems, Inc. Engineered scaffolds for promoting growth of cells
WO2006044904A2 (en) * 2004-10-15 2006-04-27 Vanderbilt University Nano- and micro-scale engineering of polymeric scaffolds for vascular tissue engineering
WO2006106506A2 (en) * 2005-04-04 2006-10-12 Technion Research & Development Foundation Ltd. Medical scaffold, methods of fabrication and using thereof
DE102006026592A1 (de) * 2005-12-01 2007-06-06 Ossacur Ag Träger mit Colloss
CA2593380A1 (en) * 2006-06-29 2007-12-29 Depuy Mitek, Inc. Nonwoven tissue scaffold

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA818919B (en) * 1981-04-13 1982-11-24 Seton Co Cosmetic and pharmaceutical sheet material containing polypeptides
DE3429038A1 (de) * 1984-08-07 1986-02-20 B. Braun Melsungen Ag, 3508 Melsungen Wirkstoff-depot
US4950483A (en) 1988-06-30 1990-08-21 Collagen Corporation Collagen wound healing matrices and process for their production
US5222987A (en) 1989-04-12 1993-06-29 Imperial Chemical Industries Plc Composite material for use in a prosthetic device
DE4404018A1 (de) * 1994-02-09 1995-08-10 Merck Patent Gmbh Protrahiert freisetzende Darreichungsformen enthaltend Clindamycin-Palmitat
DE19503336C2 (de) * 1995-02-02 1998-07-30 Lohmann Therapie Syst Lts Arzneiform zur Abgabe von Wirkstoffen an Wunden, Verfahren zu ihrer Herstellung und ihre Verwendung
TW501934B (en) * 1996-11-20 2002-09-11 Tapic Int Co Ltd Collagen material and process for making the same
US8679525B2 (en) * 2005-10-12 2014-03-25 David M. Dixon Wound care dressing and method using same

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040126405A1 (en) * 2002-12-30 2004-07-01 Scimed Life Systems, Inc. Engineered scaffolds for promoting growth of cells
WO2006044904A2 (en) * 2004-10-15 2006-04-27 Vanderbilt University Nano- and micro-scale engineering of polymeric scaffolds for vascular tissue engineering
WO2006106506A2 (en) * 2005-04-04 2006-10-12 Technion Research & Development Foundation Ltd. Medical scaffold, methods of fabrication and using thereof
DE102006026592A1 (de) * 2005-12-01 2007-06-06 Ossacur Ag Träger mit Colloss
CA2593380A1 (en) * 2006-06-29 2007-12-29 Depuy Mitek, Inc. Nonwoven tissue scaffold

Also Published As

Publication number Publication date
DE102007063395A1 (de) 2009-07-02
WO2009083263A2 (de) 2009-07-09

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