WO2009093872A3 - 신규한 디아민 화합물 또는 이의 약학적으로 허용가능한 염, 이의 제조방법 및 이를 포함하는 암 치료용 약학 조성물 - Google Patents

신규한 디아민 화합물 또는 이의 약학적으로 허용가능한 염, 이의 제조방법 및 이를 포함하는 암 치료용 약학 조성물 Download PDF

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Publication number
WO2009093872A3
WO2009093872A3 PCT/KR2009/000375 KR2009000375W WO2009093872A3 WO 2009093872 A3 WO2009093872 A3 WO 2009093872A3 KR 2009000375 W KR2009000375 W KR 2009000375W WO 2009093872 A3 WO2009093872 A3 WO 2009093872A3
Authority
WO
WIPO (PCT)
Prior art keywords
same
pharmaceutically acceptable
pharmaceutical composition
acceptable salts
diamine compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/KR2009/000375
Other languages
English (en)
French (fr)
Other versions
WO2009093872A2 (ko
Inventor
한균희
양지선
남미희
이철호
송두나
원미선
정경숙
김동명
유향숙
김환묵
박성규
이기호
이창우
고원진
류병환
최남송
정용미
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Korea Research Institute of Bioscience and Biotechnology KRIBB
Industry Academic Cooperation Foundation of Yonsei University
Seoul Pharma Co Ltd
Original Assignee
Korea Research Institute of Bioscience and Biotechnology KRIBB
Industry Academic Cooperation Foundation of Yonsei University
Seoul Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Korea Research Institute of Bioscience and Biotechnology KRIBB, Industry Academic Cooperation Foundation of Yonsei University, Seoul Pharma Co Ltd filed Critical Korea Research Institute of Bioscience and Biotechnology KRIBB
Publication of WO2009093872A2 publication Critical patent/WO2009093872A2/ko
Publication of WO2009093872A3 publication Critical patent/WO2009093872A3/ko
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
    • C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C311/03—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the sulfonamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C311/05—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the sulfonamide groups bound to hydrogen atoms or to acyclic carbon atoms to acyclic carbon atoms of hydrocarbon radicals substituted by nitrogen atoms, not being part of nitro or nitroso groups
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01B—SOIL WORKING IN AGRICULTURE OR FORESTRY; PARTS, DETAILS, OR ACCESSORIES OF AGRICULTURAL MACHINES OR IMPLEMENTS, IN GENERAL
    • A01B1/00—Hand tools
    • A01B1/02—Spades; Shovels
    • A01B1/028—Spades; Shovels with ground abutment shoes or earth anchors for facilitating lifting
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/34—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
    • C07C233/35—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/36—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/34—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
    • C07C233/42—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
    • C07C233/43—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of a saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
    • C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C311/08—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • E—FIXED CONSTRUCTIONS
    • E01—CONSTRUCTION OF ROADS, RAILWAYS, OR BRIDGES
    • E01H—STREET CLEANING; CLEANING OF PERMANENT WAYS; CLEANING BEACHES; DISPERSING OR PREVENTING FOG IN GENERAL CLEANING STREET OR RAILWAY FURNITURE OR TUNNEL WALLS
    • E01H5/00—Removing snow or ice from roads or like surfaces; Grading or roughening snow or ice
    • E01H5/02—Hand implements

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Soil Sciences (AREA)
  • Environmental Sciences (AREA)
  • Architecture (AREA)
  • Civil Engineering (AREA)
  • Structural Engineering (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

본 발명은 신규한 디아민 화합물 또는 이의 약학적으로 허용가능한 염, 이의 제조방법 및 이를 포함하는 암 치료용 약학 조성물에 관한 것이다. 본 발명에 따른 화합물은 종양세포 성장 억제 효과가 우수하므로, 암 질환 치료에 유용하게 이용될 수 있다.
PCT/KR2009/000375 2008-01-24 2009-01-23 신규한 디아민 화합물 또는 이의 약학적으로 허용가능한 염, 이의 제조방법 및 이를 포함하는 암 치료용 약학 조성물 Ceased WO2009093872A2 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2008-0007548 2008-01-24
KR20080007548 2008-01-24

Publications (2)

Publication Number Publication Date
WO2009093872A2 WO2009093872A2 (ko) 2009-07-30
WO2009093872A3 true WO2009093872A3 (ko) 2009-11-05

Family

ID=40901558

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2009/000375 Ceased WO2009093872A2 (ko) 2008-01-24 2009-01-23 신규한 디아민 화합물 또는 이의 약학적으로 허용가능한 염, 이의 제조방법 및 이를 포함하는 암 치료용 약학 조성물

Country Status (2)

Country Link
KR (1) KR20090082155A (ko)
WO (1) WO2009093872A2 (ko)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8118922B2 (en) 2009-05-18 2012-02-21 Xerox Corporation Pigmented phase change inks containing low molecular weight quaternary ammonium salt dispersants
US8101801B2 (en) 2009-05-18 2012-01-24 Xerox Corporation Low molecular weight quaternary ammonium salt dispersants
JP2011184344A (ja) * 2010-03-08 2011-09-22 Kao Corp ｐ２１発現促進剤
JP6285164B2 (ja) * 2013-12-05 2018-02-28 デクセリアルズ株式会社 化合物、熱硬化性樹脂組成物、及び熱硬化性シート
AU2017267634C1 (en) * 2016-05-16 2022-05-26 The Board Of Regents Of The University Of Texas System Cationic sulfonamide amino lipids and amphiphilic zwitterionic amino lipids

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2177314C2 (ru) * 2000-03-22 2001-12-27 Кривошеин Юрий Семенович Состав с антисептическими, репаративными и болеутоляющими свойствами
WO2007071428A2 (en) * 2005-12-22 2007-06-28 Isagro S.P.A. Oraganic derivatives, their salts and use for the control of phyto pathogens
WO2007149461A2 (en) * 2006-06-22 2007-12-27 Eastman Kodak Company Toner particles of controlled morphology

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2177314C2 (ru) * 2000-03-22 2001-12-27 Кривошеин Юрий Семенович Состав с антисептическими, репаративными и болеутоляющими свойствами
WO2007071428A2 (en) * 2005-12-22 2007-06-28 Isagro S.P.A. Oraganic derivatives, their salts and use for the control of phyto pathogens
WO2007149461A2 (en) * 2006-06-22 2007-12-27 Eastman Kodak Company Toner particles of controlled morphology

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
DATABASE CAPLUS Database accession no. 15809-19-5 *
DATABASE CAPLUS Database accession no. 172157-12-9 *
DATABASE CAPLUS Database accession no. 196403-02-8 *
DATABASE CAPLUS Database accession no. 52513-11-8 *
DATABASE CAPLUS Database accession no. 65694-09-9 *
TURNES-CAROU, I. ET AL.: "Simultaneous separation of amidoamines and benzalkonium chloride surfactants by capillary zone electrophoresis", CHROMATOGRAPHIA, vol. 56, no. 9/10, 2002, pages 605 - 609 *

Also Published As

Publication number Publication date
KR20090082155A (ko) 2009-07-29
WO2009093872A2 (ko) 2009-07-30

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