WO2009103754A3 - Nouvelle utilisation de 3,3'-diindolylméthane - Google Patents

Nouvelle utilisation de 3,3'-diindolylméthane Download PDF

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Publication number
WO2009103754A3
WO2009103754A3 PCT/EP2009/051958 EP2009051958W WO2009103754A3 WO 2009103754 A3 WO2009103754 A3 WO 2009103754A3 EP 2009051958 W EP2009051958 W EP 2009051958W WO 2009103754 A3 WO2009103754 A3 WO 2009103754A3
Authority
WO
WIPO (PCT)
Prior art keywords
diindolylmethane
novel use
cas1968
retard
aging
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2009/051958
Other languages
English (en)
Other versions
WO2009103754A2 (fr
Inventor
Hubert Hug
Bernd Musselr
Daniel Raederstorff
Ying Wang-Schmidt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DSM IP Assets BV
Original Assignee
DSM IP Assets BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DSM IP Assets BV filed Critical DSM IP Assets BV
Publication of WO2009103754A2 publication Critical patent/WO2009103754A2/fr
Publication of WO2009103754A3 publication Critical patent/WO2009103754A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Polymers & Plastics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Botany (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

L'invention concerne une nouvelle utilisation de 3,3'-diindolylméthane (CAS1968-05-4) et/ou de ses dérivés sous la forme d'une composition pharmaceutique et/ou nutritionnelle pour retarder ou différer les signes caractéristiques du vieillissement et/ou les changements pathologiques liés à l'âge.
PCT/EP2009/051958 2008-02-19 2009-02-19 Nouvelle utilisation de 3,3'-diindolylméthane Ceased WO2009103754A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08003003 2008-02-19
EP08003003.4 2008-02-19

Publications (2)

Publication Number Publication Date
WO2009103754A2 WO2009103754A2 (fr) 2009-08-27
WO2009103754A3 true WO2009103754A3 (fr) 2009-11-12

Family

ID=40983389

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2009/051958 Ceased WO2009103754A2 (fr) 2008-02-19 2009-02-19 Nouvelle utilisation de 3,3'-diindolylméthane

Country Status (1)

Country Link
WO (1) WO2009103754A2 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201105050D0 (en) 2011-03-25 2011-05-11 Iiaa Ltd Pharmaceutical agent
GB2528482A (en) * 2014-07-23 2016-01-27 Skintech Life Science Ltd Pharmaceutical agent
KR20180081361A (ko) * 2017-01-06 2018-07-16 연세대학교 산학협력단 인돌-3-카비놀 또는 이의 약학적으로 허용 가능한 염을 유효성분으로 포함하는 근육 질환 예방 또는 치료용 조성물
WO2021254752A1 (fr) * 2020-06-19 2021-12-23 Unilever Ip Holdings B.V. Utilisation de composés de diindolylméthane pour traiter les signes du vieillissement cutané

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999049851A1 (fr) * 1998-04-01 1999-10-07 Bioresponse, L.L.C. Systeme d'apport d'elements nutritifs
WO2001020991A1 (fr) * 1999-09-23 2001-03-29 Bioresponse L.L.C. Produits phytochimiques favorisant la perte de poids
JP2003081848A (ja) * 2001-09-13 2003-03-19 Maruzen Pharmaceut Co Ltd 活性酸素消去剤、該活性酸素消去剤を配合した化粧料及び飲食物
WO2003034992A2 (fr) * 2001-10-23 2003-05-01 Bioresponse, L.L.C. Di-indolylmethane pour le traitement d'infections par le papillomavirus humain
WO2006105196A2 (fr) * 2005-03-28 2006-10-05 Bioresponse, L.L.C. Compositions a base de diindolylmethane et leurs procedes d'utilisation pour favoriser la sante de la muqueuse buccale et la sante des os
WO2007096886A2 (fr) * 2006-02-27 2007-08-30 Lycored Ltd. Composition et procédés de traitement et de prévention de la dégénérescence maculaire liée à l'âge

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999049851A1 (fr) * 1998-04-01 1999-10-07 Bioresponse, L.L.C. Systeme d'apport d'elements nutritifs
WO2001020991A1 (fr) * 1999-09-23 2001-03-29 Bioresponse L.L.C. Produits phytochimiques favorisant la perte de poids
JP2003081848A (ja) * 2001-09-13 2003-03-19 Maruzen Pharmaceut Co Ltd 活性酸素消去剤、該活性酸素消去剤を配合した化粧料及び飲食物
WO2003034992A2 (fr) * 2001-10-23 2003-05-01 Bioresponse, L.L.C. Di-indolylmethane pour le traitement d'infections par le papillomavirus humain
WO2006105196A2 (fr) * 2005-03-28 2006-10-05 Bioresponse, L.L.C. Compositions a base de diindolylmethane et leurs procedes d'utilisation pour favoriser la sante de la muqueuse buccale et la sante des os
WO2007096886A2 (fr) * 2006-02-27 2007-08-30 Lycored Ltd. Composition et procédés de traitement et de prévention de la dégénérescence maculaire liée à l'âge

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
AGGARWAL BHARAT B ET AL: "Molecular targets and anticancer potential of indole-3-carbinol and its derivatives.", CELL CYCLE (GEORGETOWN, TEX.) SEP 2005, vol. 4, no. 9, September 2005 (2005-09-01), pages 1201 - 1215, XP008087499, ISSN: 1551-4005 *
GONG YIXUAN ET AL: "3,3'-Diindolylmethane is a novel mitochondrial H(+)-ATP synthase inhibitor that can induce p21(Cip1/Waf1) expression by induction of oxidative stress in human breast cancer cells.", CANCER RESEARCH 1 MAY 2006, vol. 66, no. 9, 1 May 2006 (2006-05-01), pages 4880 - 4887, XP002545928, ISSN: 0008-5472 *

Also Published As

Publication number Publication date
WO2009103754A2 (fr) 2009-08-27

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