WO2009106972A3 - Dental composition for desensitizing, disinfecting and protecting exposed dentine - Google Patents

Dental composition for desensitizing, disinfecting and protecting exposed dentine Download PDF

Info

Publication number
WO2009106972A3
WO2009106972A3 PCT/IB2009/000372 IB2009000372W WO2009106972A3 WO 2009106972 A3 WO2009106972 A3 WO 2009106972A3 IB 2009000372 W IB2009000372 W IB 2009000372W WO 2009106972 A3 WO2009106972 A3 WO 2009106972A3
Authority
WO
WIPO (PCT)
Prior art keywords
desensitizing
disinfecting
composition
dentine
calcium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2009/000372
Other languages
French (fr)
Other versions
WO2009106972A2 (en
Inventor
Alessandro Tosetti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ITALMED Srl
Original Assignee
ITALMED Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ITALMED Srl filed Critical ITALMED Srl
Publication of WO2009106972A2 publication Critical patent/WO2009106972A2/en
Publication of WO2009106972A3 publication Critical patent/WO2009106972A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/362—Polycarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/43—Guanidines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • A61K8/8152—Homopolymers or copolymers of esters, e.g. (meth)acrylic acid esters; Compositions of derivatives of such polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Emergency Medicine (AREA)
  • Dental Preparations (AREA)
  • Cosmetics (AREA)

Abstract

A composition for desensitizing, disinfecting and protecting exposed dentine comprising a substance that causes the precipitation of a calcium- containing substance compound inside the dentinal tubules, in particular, oxalic acid, potassium oxalate or a fluorine salt, and an acrylic polymer (preferably 2-hydroxyethylmetacrylate) for stabilizing the precipitated calcium- containing substance. The composition has a higher efficiency than common use desensitizing substances because it assists adhesion of insoluble calcium oxalate and calcium fluoride crystals, deep inside the dentinal tubules, thus stabilizing the occlusion of the tubules. The presence of a disinfecting substance further improves the composition efficiency; in particular, cationic disinfecting substances have a desensitizing efficacy when applied on exposed dentine since they reduce bacterial plaque, and limit therefore the reaction and degradation products of the bacterial plaque that could otherwise penetrate the dentinal tubules, which are pervious due to dentine exposition.
PCT/IB2009/000372 2008-02-26 2009-02-26 Dental composition for desensitizing, disinfecting and protecting exposed dentine Ceased WO2009106972A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITFI20080034 ITFI20080034A1 (en) 2008-02-26 2008-02-26 DENTAL COMPOSITION FOR THE DESENSITIZATION OF DISINFECTION AND PROTECTION OF EXPOSED DENTINE.
ITFI2008A000034 2008-02-26

Publications (2)

Publication Number Publication Date
WO2009106972A2 WO2009106972A2 (en) 2009-09-03
WO2009106972A3 true WO2009106972A3 (en) 2009-10-22

Family

ID=40291537

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2009/000372 Ceased WO2009106972A2 (en) 2008-02-26 2009-02-26 Dental composition for desensitizing, disinfecting and protecting exposed dentine

Country Status (2)

Country Link
IT (1) ITFI20080034A1 (en)
WO (1) WO2009106972A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITFI20120250A1 (en) * 2012-11-19 2014-05-20 Italmed Srl COMPOSITION FOR DENTAL USE FOR PRESERVATION OF THE RESIN-DENTINE LINK
CA2928931C (en) * 2013-10-28 2019-03-05 The Procter & Gamble Company Oral care compositions for tooth desensitizing
KR102076268B1 (en) * 2015-04-17 2020-02-11 주식회사 엘지생활건강 Oral composition
WO2022165467A1 (en) * 2021-02-01 2022-08-04 The Procter & Gamble Company Oral composition comprising oxalic acid

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4659751A (en) * 1983-01-10 1987-04-21 American Dental Association Health Foundation Simplified method for obtained strong adhesive bonding of composites to dentin, enamel and other substrates
US5693315A (en) * 1996-06-10 1997-12-02 Abco Trust Mammal tooth treating composition
WO1999044570A1 (en) * 1998-03-06 1999-09-10 Italmed S.N.C. Di Galli G. E Pacini G. Desensitizing dental composition
EP0976386A1 (en) * 1998-07-28 2000-02-02 Block Drug Company Inc. Polymeric desensitizing compositions
WO2002015809A2 (en) * 2000-08-21 2002-02-28 Block Drug Company, Inc. Dental composition for hypersensitive teeth
JP2002302429A (en) * 2001-04-03 2002-10-18 Nippon Zettoc Co Ltd Oral composition
US20060183081A1 (en) * 2004-09-27 2006-08-17 Al Bevilacqua Tooth bleaching system and method
US20070258916A1 (en) * 2006-04-14 2007-11-08 Oregon Health & Science University Oral compositions for treating tooth hypersensitivity

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4659751A (en) * 1983-01-10 1987-04-21 American Dental Association Health Foundation Simplified method for obtained strong adhesive bonding of composites to dentin, enamel and other substrates
US5693315A (en) * 1996-06-10 1997-12-02 Abco Trust Mammal tooth treating composition
WO1999044570A1 (en) * 1998-03-06 1999-09-10 Italmed S.N.C. Di Galli G. E Pacini G. Desensitizing dental composition
EP0976386A1 (en) * 1998-07-28 2000-02-02 Block Drug Company Inc. Polymeric desensitizing compositions
WO2002015809A2 (en) * 2000-08-21 2002-02-28 Block Drug Company, Inc. Dental composition for hypersensitive teeth
JP2002302429A (en) * 2001-04-03 2002-10-18 Nippon Zettoc Co Ltd Oral composition
US20060183081A1 (en) * 2004-09-27 2006-08-17 Al Bevilacqua Tooth bleaching system and method
US20070258916A1 (en) * 2006-04-14 2007-11-08 Oregon Health & Science University Oral compositions for treating tooth hypersensitivity

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DITTGEN M ET AL: "ACRYLIC POLYMERS A REVIEW OF PHARMACEUTICAL APPLICATIONS", SCIENCES TECHNIQUES ET PRATIQUES STP PHARMA SCIENCES, PARIS, FR, vol. 7, no. 6, 1 January 1997 (1997-01-01), pages 403 - 437, XP001030915, ISSN: 1157-1489 *

Also Published As

Publication number Publication date
ITFI20080034A1 (en) 2009-08-27
WO2009106972A2 (en) 2009-09-03

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