WO2009117112A3 - Appareil de dispersion de poudre, procédé de fabrication et d’utilisation de l’appareil, composants pouvant être utilisés sur l’appareil et d’autres dispositifs, et divers agents actifs - Google Patents

Appareil de dispersion de poudre, procédé de fabrication et d’utilisation de l’appareil, composants pouvant être utilisés sur l’appareil et d’autres dispositifs, et divers agents actifs Download PDF

Info

Publication number
WO2009117112A3
WO2009117112A3 PCT/US2009/001716 US2009001716W WO2009117112A3 WO 2009117112 A3 WO2009117112 A3 WO 2009117112A3 US 2009001716 W US2009001716 W US 2009001716W WO 2009117112 A3 WO2009117112 A3 WO 2009117112A3
Authority
WO
WIPO (PCT)
Prior art keywords
apparatuses
apparatu
devices
powder dispersion
receptacle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2009/001716
Other languages
English (en)
Other versions
WO2009117112A2 (fr
Inventor
Mark Glusker
William W. Alston
George S. Axford
John Palmer-Felgate
Jonathan Wilkins
Willard R. Foss
Nagaraja Rao
Mark Postich
Neeraj R. Pakala
David S. Maltz
Jeffry G. Weers
Gal Cohen
Keith Try Ung
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis AG filed Critical Novartis AG
Priority to EP09722897A priority Critical patent/EP2257326A2/fr
Publication of WO2009117112A2 publication Critical patent/WO2009117112A2/fr
Publication of WO2009117112A3 publication Critical patent/WO2009117112A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/001—Particle size control
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0005—Details of inhalators; Constructional features thereof with means for agitating the medicament
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0013—Details of inhalators; Constructional features thereof with inhalation check valves
    • A61M15/0016—Details of inhalators; Constructional features thereof with inhalation check valves located downstream of the dispenser, i.e. traversed by the product
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033—Details of the piercing or cutting means
    • A61M15/0035—Piercing means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033—Details of the piercing or cutting means
    • A61M15/0038—Cutting means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033—Details of the piercing or cutting means
    • A61M15/0041—Details of the piercing or cutting means with movable piercing or cutting means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Medicinal Preparation (AREA)

Abstract

La présente invention concerne des procédés et des appareils pour la libération pulmonaire d’une composition, tels que des procédés et des appareils pour disperser des médicaments sous forme de poudre sèche pour une inhalation par un patient. L’invention concerne également des éléments ou des aspects des appareils, comprenant des mécanismes de perforation de réceptacle, des dispositifs d’ouverture, des dispositifs de percussion sur réceptacle et des dispositifs ou des systèmes de verrouillage de réceptacle.
PCT/US2009/001716 2008-03-21 2009-03-18 Appareil de dispersion de poudre, procédé de fabrication et d’utilisation de l’appareil, composants pouvant être utilisés sur l’appareil et d’autres dispositifs, et divers agents actifs Ceased WO2009117112A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP09722897A EP2257326A2 (fr) 2008-03-21 2009-03-18 Appareil de dispersion de poudre

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US7026008P 2008-03-21 2008-03-21
US61/070,260 2008-03-21
US12607808P 2008-04-30 2008-04-30
US61/126,078 2008-04-30

Publications (2)

Publication Number Publication Date
WO2009117112A2 WO2009117112A2 (fr) 2009-09-24
WO2009117112A3 true WO2009117112A3 (fr) 2010-04-22

Family

ID=40792785

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2009/001716 Ceased WO2009117112A2 (fr) 2008-03-21 2009-03-18 Appareil de dispersion de poudre, procédé de fabrication et d’utilisation de l’appareil, composants pouvant être utilisés sur l’appareil et d’autres dispositifs, et divers agents actifs

Country Status (2)

Country Link
EP (1) EP2257326A2 (fr)
WO (1) WO2009117112A2 (fr)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2394589T3 (es) 2007-12-14 2013-02-04 Aerodesigns, Inc Suministro de productos alimenticios transformables en aerosol
US8623395B2 (en) 2010-01-29 2014-01-07 Forsight Vision4, Inc. Implantable therapeutic device
CA3045436C (fr) 2009-01-29 2025-10-07 Forsight Vision4, Inc. Administration d'un medicament dans le segment posterieur
US10166142B2 (en) 2010-01-29 2019-01-01 Forsight Vision4, Inc. Small molecule delivery with implantable therapeutic device
PT105065B (pt) 2010-04-26 2012-07-31 Hovione Farmaciencia S A Um inalador simples de cápsulas
CN103209664A (zh) 2010-08-05 2013-07-17 弗赛特影像4股份有限公司 可植入的治疗装置
CN103153316B (zh) 2010-08-05 2015-08-19 弗赛特影像4股份有限公司 组合药物递送方法和设备
WO2012019136A2 (fr) 2010-08-05 2012-02-09 Forsight Vision 4, Inc. Appareil d'injection et procédé d'administration de médicament
US8689439B2 (en) 2010-08-06 2014-04-08 Abbott Laboratories Method for forming a tube for use with a pump delivery system
US8372845B2 (en) 2010-09-17 2013-02-12 Novartis Ag Pyrazine derivatives as enac blockers
US8377001B2 (en) 2010-10-01 2013-02-19 Abbott Laboratories Feeding set for a peristaltic pump system
US8377000B2 (en) 2010-10-01 2013-02-19 Abbott Laboratories Enteral feeding apparatus having a feeding set
AU2011329656B2 (en) 2010-11-19 2017-01-05 Forsight Vision4, Inc. Therapeutic agent formulations for implanted devices
JOP20120023B1 (ar) 2011-02-04 2022-03-14 Novartis Ag صياغات مساحيق جافة من جسيمات تحتوي على واحد أو اثنين من المواد الفعالة لعلاج امراض ممرات الهواء الانسدادية او الالتهابية
EP2726016B1 (fr) 2011-06-28 2023-07-19 ForSight Vision4, Inc. Un appareil pour collecter un échantillon de fluide à partir d'une chambre réservoir d'un dispositif thérapeutique pour l'oeil
SI2755600T1 (sl) 2011-09-16 2021-08-31 Forsight Vision4, Inc. Naprava za izmenjavo tekočine
US10010448B2 (en) 2012-02-03 2018-07-03 Forsight Vision4, Inc. Insertion and removal methods and apparatus for therapeutic devices
US8809340B2 (en) 2012-03-19 2014-08-19 Novartis Ag Crystalline form
EP2935249B1 (fr) 2012-12-19 2018-12-12 Novartis AG Inhibiteurs d'autotaxine
AU2014236455B2 (en) 2013-03-14 2018-07-12 Forsight Vision4, Inc. Systems for sustained intraocular delivery of low solubility compounds from a port delivery system implant
AU2014241163B2 (en) 2013-03-28 2018-09-27 Forsight Vision4, Inc. Ophthalmic implant for delivering therapeutic substances
EP3022201A1 (fr) 2013-07-18 2016-05-25 Novartis AG Inhibiteurs de l'autotaxine
PT3022202T (pt) 2013-07-18 2019-09-03 Novartis Ag Inibidores da autotaxina compreendendo um núcleo beteroaromático anel-benzilo-amida-ciclo
US20170037030A1 (en) 2014-04-24 2017-02-09 Novartis Ag Autotaxin inhibitors
RU2695563C2 (ru) 2014-07-15 2019-07-24 Форсайт Вижн4, Инк. Способ и устройство для доставки глазного имплантата
MY182793A (en) 2014-08-08 2021-02-05 Forsight Vision4 Inc Stable and soluble formulations of receptor tyrosine kinase inhibitors, and methods of preparation thereof
JP7037360B2 (ja) 2014-11-10 2022-03-16 フォーサイト・ビジョン フォー・インコーポレーテッド 拡張可能な薬物送達デバイス
EP3283151B1 (fr) * 2015-04-15 2022-07-20 Philip Morris Products S.A. Inhalateur de poudre sèche et procédé d'utilisation
KR20180084104A (ko) 2015-11-20 2018-07-24 포사이트 비젼4, 인크. 연장 방출 약물 전달 장치를 위한 다공성 구조물
BR112018070383A2 (pt) 2016-04-05 2019-02-05 Forsight Vision4 Inc dispositivos para aplicação de fármaco oculares implantáveis
US10898494B2 (en) * 2016-05-05 2021-01-26 Liquidia Technologies, Inc. Dry powder treprostinil for the treatment of pulmonary hypertension
CN115607358A (zh) 2017-11-21 2023-01-17 弗赛特影像4股份有限公司 用于可扩展端口递送系统的流体交换装置及使用方法
CN111834656B (zh) * 2020-07-25 2022-03-22 山东交通学院 一种优化的单相掺杂镓酸镧电解质制备装置及方法
USD1033637S1 (en) 2022-01-24 2024-07-02 Forsight Vision4, Inc. Fluid exchange device
WO2025096521A1 (fr) * 2023-10-30 2025-05-08 Insmed Incorporated Dispositif d'administration de médicament, couvercle et procédés d'administration de médicament

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3888253A (en) * 1972-08-04 1975-06-10 Beecham Group Ltd Device for administration of medicines
WO1999039760A1 (fr) * 1998-02-05 1999-08-12 Unisia Jecs Corporation Inhalateur de medicaments
US6668827B2 (en) * 2000-05-16 2003-12-30 Nektar Therapeutics Systems devices and methods for opening receptacles having a powder to be fluidized
WO2006054021A2 (fr) * 2004-11-16 2006-05-26 Valois Sas Dispositif de distribution de produit fluide
WO2008051621A2 (fr) * 2006-10-25 2008-05-02 Novartis Ag Appareil de dispersion de poudre, procédé de fabrication et d'utilisation de l'appareil et composant pouvant être utilisé sur l'appareil et d'autres dispositifs

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3888253A (en) * 1972-08-04 1975-06-10 Beecham Group Ltd Device for administration of medicines
WO1999039760A1 (fr) * 1998-02-05 1999-08-12 Unisia Jecs Corporation Inhalateur de medicaments
US6668827B2 (en) * 2000-05-16 2003-12-30 Nektar Therapeutics Systems devices and methods for opening receptacles having a powder to be fluidized
WO2006054021A2 (fr) * 2004-11-16 2006-05-26 Valois Sas Dispositif de distribution de produit fluide
WO2008051621A2 (fr) * 2006-10-25 2008-05-02 Novartis Ag Appareil de dispersion de poudre, procédé de fabrication et d'utilisation de l'appareil et composant pouvant être utilisé sur l'appareil et d'autres dispositifs

Also Published As

Publication number Publication date
WO2009117112A2 (fr) 2009-09-24
EP2257326A2 (fr) 2010-12-08

Similar Documents

Publication Publication Date Title
WO2008051621A3 (fr) Appareil de dispersion de poudre, procédé de fabrication et d'utilisation de l'appareil et composant pouvant être utilisé sur l'appareil et d'autres dispositifs
IL226853A (en) Annotations of 3 [(2,1-oxazole-4-yl) methoxy] -8-azabicyclo [1.2.3] octane, processes for their preparation, pharmaceutical preparations containing them and their use in the preparation of drugs for the treatment of fxr
TN2012000566A1 (en) Dry powder formulation comprising an antimuscarinic drug
AU2010303040A8 (en) Improvements to pressurised metered dose inhalers
IL205742A (en) 4 - (4-Cyano-2-Theoaryl) dihydropyrimidinones, their preparation processes, medications containing them and their use
WO2011041461A3 (fr) Composés polycycliques utiles en tant qu'antagonistes du récepteur de l'acide lysophosphatidique
WO2012078593A3 (fr) Antagonistes des récepteurs de l'acide lysophosphatidique et utilisations de ceux-ci
IL198289A (en) Processed dihydropyrazolones, processes for their preparation, medicinal preparations containing them and their use in the preparation of medicinal preparations
IL233677A (en) Benzysacazole Compounds Aminopyrazolo-Primidine Converted, Pharmaceuticals Containing Them, and Use of Drug Manufacturing Composition
MX346424B (es) Formulacion de polvo seco que comprende un inhibidor de fosfodiesterasa.
WO2011041694A3 (fr) Composés utiles comme antagonistes du récepteur de l'acide lysophosphatidique (lpa)
WO2011017350A3 (fr) Composés en tant qu'antagonistes du récepteur de l'acide lysophosphatidique
WO2010037059A3 (fr) Antagonistes hétéroaryliques des récepteurs de prostaglandine d<sb>2</sb>
IL244239A0 (en) (r5,s2)-6-(benzyloxy/allyloxy)-7-oxo-1,6-diazabicyclo[3.2.1.]octane-2-carboxylates, methods for their preparation and use of (r5,s2)-tert-butyl- 6-(benzyloxy)-7-oxo-1,6-diazabicyclo[3.2.1]octane-2-carboxylate for the preparation of anti-infective drugs
HK1221653A1 (zh) 用於呼吸递送三种或更多种活性剂的组合物、方法和系统
WO2007117661A3 (fr) Microparticules médicamenteuses
WO2012075407A3 (fr) Dispositifs de prélèvement sanguin contenant un agent de stabilisation du sang
UA103668C2 (ru) Ингалятор для ингаляции сухого порошка с механизмом блокирования
EP4360626A3 (fr) Utilisation de stéarate dans une formulation inhalable
WO2011084316A3 (fr) Formulations et procédés pour le réglage de l'administration de particules d'une certaine taille dans un aérosol-doseur
WO2011008662A9 (fr) Dispositifs de distribution de poudre et procédés d'utilisation de ceux-ci
IL224430B (en) Liquid pharmaceutical formulation comprising st-246 and a beta-cyclodextrin, a process of making the liquid formulation, a unit dosage liquid formulation and a process for preparing a water-soluble solid st-246 pharmaceutical formulation
WO2010009140A3 (fr) Procédés, systèmes et dispositifs destinés à l'administration de dioxyde de chlore
WO2014007772A3 (fr) Compositions d'inhalation contenant du glucose anhydre
EP2442642A4 (fr) Dispersion biocide stabilisée par l'intermédiaire de particules porteuses submicroniques, procédé de fabrication de celle-ci et composition de celle-ci

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 09722897

Country of ref document: EP

Kind code of ref document: A2

NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 2009722897

Country of ref document: EP