WO2010077997A3 - Method and apparatus for determining heart rate variability using wavelet transformation - Google Patents

Method and apparatus for determining heart rate variability using wavelet transformation Download PDF

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Publication number
WO2010077997A3
WO2010077997A3 PCT/US2009/068336 US2009068336W WO2010077997A3 WO 2010077997 A3 WO2010077997 A3 WO 2010077997A3 US 2009068336 W US2009068336 W US 2009068336W WO 2010077997 A3 WO2010077997 A3 WO 2010077997A3
Authority
WO
WIPO (PCT)
Prior art keywords
wavelet transformation
heart rate
rate variability
extent
determining heart
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2009/068336
Other languages
French (fr)
Other versions
WO2010077997A2 (en
Inventor
Kayvan Najarian
Kevin Ward
David Andre
Nisarg Vyas
Eric Teller
John M. Stivoric
Jonathan Farringdon
Scott Boehmke
James Gasbarro
Soo-Yeon Ji
Abed Al Raoof
Raymond Pelletier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Virginia Commonwealth University
Bodymedia Inc
Original Assignee
Virginia Commonwealth University
Bodymedia Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2009/006234 external-priority patent/WO2010065067A1/en
Application filed by Virginia Commonwealth University, Bodymedia Inc filed Critical Virginia Commonwealth University
Priority to EP09836926.7A priority Critical patent/EP2375973A4/en
Priority to CA2747057A priority patent/CA2747057A1/en
Priority to US13/140,165 priority patent/US20120123232A1/en
Publication of WO2010077997A2 publication Critical patent/WO2010077997A2/en
Publication of WO2010077997A3 publication Critical patent/WO2010077997A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/0205—Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/024—Measuring pulse rate or heart rate
    • A61B5/02405—Determining heart rate variability
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316—Modalities, i.e. specific diagnostic methods
    • A61B5/318—Heart-related electrical modalities, e.g. electrocardiography [ECG]
    • A61B5/346—Analysis of electrocardiograms
    • A61B5/349—Detecting specific parameters of the electrocardiograph cycle
    • A61B5/366—Detecting abnormal QRS complex, e.g. widening
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
    • A61B5/412—Detecting or monitoring sepsis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7203—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal
    • A61B5/7207—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal of noise induced by motion artifacts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7225—Details of analogue processing, e.g. isolation amplifier, gain or sensitivity adjustment, filtering, baseline or drift compensation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235—Details of waveform analysis
    • A61B5/7253—Details of waveform analysis characterised by using transforms
    • A61B5/726—Details of waveform analysis characterised by using transforms using Wavelet transforms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/021—Measuring pressure in heart or blood vessels
    • A61B5/022—Measuring pressure in heart or blood vessels by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers
    • A61B5/02208—Measuring pressure in heart or blood vessels by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers using the Korotkoff method
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/22—Ergometry; Measuring muscular strength or the force of a muscular blow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6813—Specially adapted to be attached to a specific body part
    • A61B5/6824—Arm or wrist
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7203—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal
    • A61B5/7207—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal of noise induced by motion artifacts
    • A61B5/721—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal of noise induced by motion artifacts using a separate sensor to detect motion or using motion information derived from signals other than the physiological signal to be measured
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235—Details of waveform analysis
    • A61B5/7239—Details of waveform analysis using differentiation including higher order derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235—Details of waveform analysis
    • A61B5/7264—Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems
    • A61B5/7267—Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems involving training the classification device

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Surgery (AREA)
  • Public Health (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Physiology (AREA)
  • Signal Processing (AREA)
  • Artificial Intelligence (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Psychiatry (AREA)
  • Vascular Medicine (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Power Engineering (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)

Abstract

The present invention relates to advanced signal processing methods including digital wavelet transformation to analyze heart-related electronic signals and extract features that can accurately identify various states of the cardiovascular system. The invention may be utilized to estimate the extent of blood volume loss, distinguish blood volume loss from physiological activities associated with exercise, and predict the presence and extent of cardiovascular disease in general.
PCT/US2009/068336 2008-12-16 2009-12-16 Method and apparatus for determining heart rate variability using wavelet transformation Ceased WO2010077997A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP09836926.7A EP2375973A4 (en) 2008-12-16 2009-12-16 METHOD AND APPARATUS FOR DETERMINING HEART RATE VARIABILITY USING WAVELET TRANSFORMATION
CA2747057A CA2747057A1 (en) 2008-12-16 2009-12-16 Method and apparatus for determining heart rate variability using wavelet transformation
US13/140,165 US20120123232A1 (en) 2008-12-16 2009-12-16 Method and apparatus for determining heart rate variability using wavelet transformation

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US12280408P 2008-12-16 2008-12-16
US61/122,804 2008-12-16
US16728709P 2009-04-07 2009-04-07
US61/167,287 2009-04-07
PCT/US2009/006234 WO2010065067A1 (en) 2008-11-20 2009-11-20 Method and apparatus for determining critical care parameters
USPCT/US2009/006234 2009-11-20

Publications (2)

Publication Number Publication Date
WO2010077997A2 WO2010077997A2 (en) 2010-07-08
WO2010077997A3 true WO2010077997A3 (en) 2010-10-14

Family

ID=42310544

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2009/068336 Ceased WO2010077997A2 (en) 2008-12-16 2009-12-16 Method and apparatus for determining heart rate variability using wavelet transformation

Country Status (3)

Country Link
EP (1) EP2375973A4 (en)
CA (1) CA2747057A1 (en)
WO (1) WO2010077997A2 (en)

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US9839364B2 (en) 2009-10-06 2017-12-12 University Of Virginia Patent Foundation Ventricular activation (RR) entropy change as a predictor of sudden cardiac death in cardiac resynchronization therapy patients
WO2013170232A1 (en) * 2012-05-11 2013-11-14 University Of Virginia Patent Foundation Ventricular activation (rr) entropy change as a predictor of sudden cardiac death in cardiac resynchronization therapy patients
CN103002800B (en) 2010-05-18 2015-08-26 佐尔医药公司 Wearable mobile medical device with multiple sensing electrodes
US9684767B2 (en) 2011-03-25 2017-06-20 Zoll Medical Corporation System and method for adapting alarms in a wearable medical device
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US8897860B2 (en) 2011-03-25 2014-11-25 Zoll Medical Corporation Selection of optimal channel for rate determination
WO2012166568A2 (en) * 2011-05-27 2012-12-06 Virginia Commonwealth University Assessment and prediction of cardiovascular status during cardiac arrest and the post-resuscitation period using signal processing and machine learning
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WO2013130957A2 (en) 2012-03-02 2013-09-06 Zoll Medical Corporation Systems and methods for configuring a wearable medical monitoring and/or treatment device
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CN105611872A (en) * 2013-10-09 2016-05-25 皇家飞利浦有限公司 An apparatus and method for evaluating multichannel ECG signals
WO2015123198A1 (en) 2014-02-12 2015-08-20 Zoll Medical Corporation System and method for adapting alarms in a wearable medical device
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US8600486B2 (en) 2011-03-25 2013-12-03 Zoll Medical Corporation Method of detecting signal clipping in a wearable ambulatory medical device
US8798729B2 (en) 2011-03-25 2014-08-05 Zoll Medical Corporation Method of detecting signal clipping in a wearable ambulatory medical device
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Also Published As

Publication number Publication date
WO2010077997A2 (en) 2010-07-08
EP2375973A2 (en) 2011-10-19
CA2747057A1 (en) 2010-07-08
EP2375973A4 (en) 2014-02-12

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