WO2012012779A3 - System and method including analytical units - Google Patents

System and method including analytical units Download PDF

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Publication number
WO2012012779A3
WO2012012779A3 PCT/US2011/045107 US2011045107W WO2012012779A3 WO 2012012779 A3 WO2012012779 A3 WO 2012012779A3 US 2011045107 W US2011045107 W US 2011045107W WO 2012012779 A3 WO2012012779 A3 WO 2012012779A3
Authority
WO
WIPO (PCT)
Prior art keywords
samples
processing
cases
preparation
analysis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2011/045107
Other languages
French (fr)
Other versions
WO2012012779A2 (en
Inventor
Brian D. Wilson
Sami D. Alaruri
David L. Anderson
Matthew S. Davis
Matthew D. Erickson
Robert B. Gwynn
Alan N. Johnson
Charles S. Kraihanzel
Garrick A. Maurer
Michael J. Rosen
Mark F. Sauerburger
Daniel R. Schmidt
Reed B. Wagner
Joshua D. Wiltsie
Thomas M. Stachelek
David L. Yang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beckman Coulter Inc
Original Assignee
Beckman Coulter Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beckman Coulter Inc filed Critical Beckman Coulter Inc
Priority to KR1020137004705A priority Critical patent/KR20130029128A/en
Priority to KR20137004525A priority patent/KR20130041255A/en
Priority to BR112013001647A priority patent/BR112013001647A2/en
Priority to JP2013520896A priority patent/JP2013535193A/en
Priority to KR1020137004704A priority patent/KR20130029127A/en
Priority to BR122013002340A priority patent/BR122013002340A2/en
Priority to EP11810501.4A priority patent/EP2596135A2/en
Priority to CN201180045939.4A priority patent/CN103119451B/en
Publication of WO2012012779A2 publication Critical patent/WO2012012779A2/en
Priority to US13/747,834 priority patent/US9285382B2/en
Priority to US13/747,606 priority patent/US8996320B2/en
Priority to US13/747,722 priority patent/US8962308B2/en
Priority to US13/747,730 priority patent/US20130203046A1/en
Priority to US13/747,945 priority patent/US9519000B2/en
Priority to US13/747,900 priority patent/US20130137166A1/en
Priority to US13/747,801 priority patent/US8956570B2/en
Priority to US13/747,888 priority patent/US8840848B2/en
Priority to US13/747,567 priority patent/US20130137087A1/en
Priority to US13/747,952 priority patent/US9140715B2/en
Priority to US13/747,697 priority patent/US9274132B2/en
Priority to US13/747,670 priority patent/US8932541B2/en
Anticipated expiration legal-status Critical
Priority to US13/747,633 priority patent/US9046455B2/en
Publication of WO2012012779A3 publication Critical patent/WO2012012779A3/en
Priority to US14/504,123 priority patent/US20150111288A1/en
Priority to US14/590,820 priority patent/US20150217291A1/en
Priority to US14/819,231 priority patent/US20150337400A1/en
Ceased legal-status Critical Current

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  • Chemical & Material Sciences (AREA)
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Abstract

Systems and methods for processing and analyzing samples are disclosed. The system may process samples, such as biological fluids, using assay cartridges which can be processed at different processing locations. In some cases, the system can be used for PCR processing. The different processing locations may include a preparation location where samples can be prepared and an analysis location where samples can be analyzed. To assist with the preparation of samples, the system may also include a number of processing stations which may include processing lanes. During the analysis of samples, in some cases, thermal cycler modules and an appropriate optical detection system can be used to detect the presence or absence of certain nucleic acid sequences in the samples. The system can be used to accurately and rapidly process samples.
PCT/US2011/045107 2010-07-23 2011-07-22 System and method including analytical units Ceased WO2012012779A2 (en)

Priority Applications (24)

Application Number Priority Date Filing Date Title
KR1020137004705A KR20130029128A (en) 2010-07-23 2011-07-22 Vessel for real time pcr
KR20137004525A KR20130041255A (en) 2010-07-23 2011-07-22 Reagent cartridge
BR112013001647A BR112013001647A2 (en) 2010-07-23 2011-07-22 system and method containing analytical units
JP2013520896A JP2013535193A (en) 2010-07-23 2011-07-22 System and method including an analyzer
KR1020137004704A KR20130029127A (en) 2010-07-23 2011-07-22 Reagent cartridge
BR122013002340A BR122013002340A2 (en) 2010-07-23 2011-07-22 test cartridge
EP11810501.4A EP2596135A2 (en) 2010-07-23 2011-07-22 System and method including analytical units
CN201180045939.4A CN103119451B (en) 2010-07-23 2011-07-22 Systems and methods for processing samples
US13/747,633 US9046455B2 (en) 2010-07-23 2013-01-23 System and method including multiple processing lanes executing processing protocols
US13/747,945 US9519000B2 (en) 2010-07-23 2013-01-23 Reagent cartridge
US13/747,952 US9140715B2 (en) 2010-07-23 2013-01-23 System and method for controlling thermal cycler modules
US13/747,722 US8962308B2 (en) 2010-07-23 2013-01-23 System and method including thermal cycler modules
US13/747,730 US20130203046A1 (en) 2010-07-23 2013-01-23 System and method including analytical units
US13/747,834 US9285382B2 (en) 2010-07-23 2013-01-23 Reaction vessel
US13/747,900 US20130137166A1 (en) 2010-07-23 2013-01-23 System and method including analytical units
US13/747,801 US8956570B2 (en) 2010-07-23 2013-01-23 System and method including analytical units
US13/747,888 US8840848B2 (en) 2010-07-23 2013-01-23 System and method including analytical units
US13/747,567 US20130137087A1 (en) 2010-07-23 2013-01-23 System and method including analytical units
US13/747,606 US8996320B2 (en) 2010-07-23 2013-01-23 System and method including analytical units
US13/747,697 US9274132B2 (en) 2010-07-23 2013-01-23 Assay cartridge with reaction well
US13/747,670 US8932541B2 (en) 2010-07-23 2013-01-23 Pipettor including compliant coupling
US14/504,123 US20150111288A1 (en) 2010-07-23 2014-10-01 System and method including analytical units
US14/590,820 US20150217291A1 (en) 2010-07-23 2015-01-06 System and method including thermal cycler modules
US14/819,231 US20150337400A1 (en) 2010-07-23 2015-08-05 System and method for controlling thermal cycler modules

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36734310P 2010-07-23 2010-07-23
US61/367,343 2010-07-23

Related Child Applications (13)

Application Number Title Priority Date Filing Date
US13/747,606 Continuation US8996320B2 (en) 2010-07-23 2013-01-23 System and method including analytical units
US13/747,888 Continuation US8840848B2 (en) 2010-07-23 2013-01-23 System and method including analytical units
US13/747,945 Continuation US9519000B2 (en) 2010-07-23 2013-01-23 Reagent cartridge
US13/747,697 Continuation US9274132B2 (en) 2010-07-23 2013-01-23 Assay cartridge with reaction well
US13/747,567 Continuation US20130137087A1 (en) 2010-07-23 2013-01-23 System and method including analytical units
US13/747,952 Continuation US9140715B2 (en) 2010-07-23 2013-01-23 System and method for controlling thermal cycler modules
US13/747,801 Continuation US8956570B2 (en) 2010-07-23 2013-01-23 System and method including analytical units
US13/747,670 Continuation US8932541B2 (en) 2010-07-23 2013-01-23 Pipettor including compliant coupling
US13/747,834 Continuation US9285382B2 (en) 2010-07-23 2013-01-23 Reaction vessel
US13/747,900 Continuation US20130137166A1 (en) 2010-07-23 2013-01-23 System and method including analytical units
US13/747,730 Continuation US20130203046A1 (en) 2010-07-23 2013-01-23 System and method including analytical units
US13/747,633 Continuation US9046455B2 (en) 2010-07-23 2013-01-23 System and method including multiple processing lanes executing processing protocols
US13/747,722 Continuation US8962308B2 (en) 2010-07-23 2013-01-23 System and method including thermal cycler modules

Publications (2)

Publication Number Publication Date
WO2012012779A2 WO2012012779A2 (en) 2012-01-26
WO2012012779A3 true WO2012012779A3 (en) 2013-01-24

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PCT/US2011/045107 Ceased WO2012012779A2 (en) 2010-07-23 2011-07-22 System and method including analytical units

Country Status (8)

Country Link
US (16) US20130203046A1 (en)
EP (13) EP2752668A3 (en)
JP (5) JP2013535193A (en)
KR (3) KR20130029127A (en)
CN (15) CN104345161B (en)
BR (2) BR112013001647A2 (en)
ES (1) ES2610468T3 (en)
WO (1) WO2012012779A2 (en)

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US10406525B1 (en) 2018-04-13 2019-09-10 Inscripta, Inc. Automated cell processing instruments comprising reagent cartridges
US10532324B1 (en) 2018-08-14 2020-01-14 Inscripta, Inc. Instruments, modules, and methods for improved detection of edited sequences in live cells
US10689669B1 (en) 2020-01-11 2020-06-23 Inscripta, Inc. Automated multi-module cell processing methods, instruments, and systems
US10858761B2 (en) 2018-04-24 2020-12-08 Inscripta, Inc. Nucleic acid-guided editing of exogenous polynucleotides in heterologous cells
US10920189B2 (en) 2019-06-21 2021-02-16 Inscripta, Inc. Genome-wide rationally-designed mutations leading to enhanced lysine production in E. coli
US10927385B2 (en) 2019-06-25 2021-02-23 Inscripta, Inc. Increased nucleic-acid guided cell editing in yeast
US11268088B2 (en) 2020-04-24 2022-03-08 Inscripta, Inc. Compositions, methods, modules and instruments for automated nucleic acid-guided nuclease editing in mammalian cells via viral delivery
US11268061B2 (en) 2018-08-14 2022-03-08 Inscripta, Inc. Detection of nuclease edited sequences in automated modules and instruments
US11787841B2 (en) 2020-05-19 2023-10-17 Inscripta, Inc. Rationally-designed mutations to the thrA gene for enhanced lysine production in E. coli
US11965154B2 (en) 2018-08-30 2024-04-23 Inscripta, Inc. Detection of nuclease edited sequences in automated modules and instruments

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US8895311B1 (en) 2001-03-28 2014-11-25 Handylab, Inc. Methods and systems for control of general purpose microfluidic devices
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US7998708B2 (en) * 2006-03-24 2011-08-16 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
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US9519000B2 (en) 2016-12-13
EP2743705A3 (en) 2014-08-20
US8962308B2 (en) 2015-02-24
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CN103540517A (en) 2014-01-29
CN103551212B (en) 2016-01-20
US9046455B2 (en) 2015-06-02
KR20130029128A (en) 2013-03-21
EP2743705B1 (en) 2016-10-12
CN103657754B (en) 2016-01-06
JP2013150623A (en) 2013-08-08
JP2016200604A (en) 2016-12-01
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US8840848B2 (en) 2014-09-23
EP2743704A3 (en) 2014-06-25
EP2752246A2 (en) 2014-07-09
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CN103675303A (en) 2014-03-26
EP2752670A2 (en) 2014-07-09
US20130130369A1 (en) 2013-05-23
BR122013002340A2 (en) 2018-10-09
US20130196422A1 (en) 2013-08-01
US20150111288A1 (en) 2015-04-23
EP2746777A2 (en) 2014-06-25
EP2749887A3 (en) 2014-10-01
US20130203046A1 (en) 2013-08-08
US20130136670A1 (en) 2013-05-30
US20130137166A1 (en) 2013-05-30
CN103725591A (en) 2014-04-16
JP2014193114A (en) 2014-10-09
KR20130029127A (en) 2013-03-21
CN103540518B (en) 2015-07-08
CN103543281B (en) 2015-04-29
CN104345161B (en) 2017-04-12
US20130137087A1 (en) 2013-05-30
BR112013001647A2 (en) 2016-05-24
ES2610468T3 (en) 2017-04-27
US9140715B2 (en) 2015-09-22
CN104345165A (en) 2015-02-11
CN103555815A (en) 2014-02-05
US20130137109A1 (en) 2013-05-30
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US20150217291A1 (en) 2015-08-06
EP2754496A3 (en) 2017-08-02
CN103555558A (en) 2014-02-05
EP2749356A3 (en) 2014-10-08
CN103657754A (en) 2014-03-26
US8996320B2 (en) 2015-03-31
EP2752668A2 (en) 2014-07-09
EP2743705A2 (en) 2014-06-18
EP2752671A3 (en) 2016-08-24
CN103551212A (en) 2014-02-05
CN104345161A (en) 2015-02-11
CN103540517B (en) 2017-05-24
CN103589627B (en) 2015-11-18
CN103555558B (en) 2016-09-28
CN103119451B (en) 2014-11-26
US20150337400A1 (en) 2015-11-26
JP6013959B2 (en) 2016-10-25
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JP5948271B2 (en) 2016-07-06
EP2752671A2 (en) 2014-07-09
CN103540530B (en) 2016-02-17
WO2012012779A2 (en) 2012-01-26
US8956570B2 (en) 2015-02-17
KR20130041255A (en) 2013-04-24
US20130143199A1 (en) 2013-06-06
EP2752246A3 (en) 2016-08-31
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JP2013535193A (en) 2013-09-12
US9285382B2 (en) 2016-03-15
US9274132B2 (en) 2016-03-01
US8932541B2 (en) 2015-01-13
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CN103675303B (en) 2016-02-03

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