WO2012138320A1 - Composition insectifuge ingérable et système associé - Google Patents

Composition insectifuge ingérable et système associé Download PDF

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Publication number
WO2012138320A1
WO2012138320A1 PCT/US2011/031093 US2011031093W WO2012138320A1 WO 2012138320 A1 WO2012138320 A1 WO 2012138320A1 US 2011031093 W US2011031093 W US 2011031093W WO 2012138320 A1 WO2012138320 A1 WO 2012138320A1
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WO
WIPO (PCT)
Prior art keywords
vitamins
ingestible
transfer agent
insect repellent
comprised
Prior art date
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Ceased
Application number
PCT/US2011/031093
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English (en)
Inventor
D Bodden
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CARRO A
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CARRO A
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Publication date
Application filed by CARRO A filed Critical CARRO A
Priority to PCT/US2011/031093 priority Critical patent/WO2012138320A1/fr
Publication of WO2012138320A1 publication Critical patent/WO2012138320A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A01N65/08—Magnoliopsida [dicotyledons]
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A01N65/08—Magnoliopsida [dicotyledons]
    • A01N65/22—Lamiaceae or Labiatae [Mint family], e.g. thyme, rosemary, skullcap, selfheal, lavender, perilla, pennyroyal, peppermint or spearmint
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
    • A01N65/08—Magnoliopsida [dicotyledons]
    • A01N65/36—Rutaceae [Rue family], e.g. lime, orange, lemon, corktree or pricklyash

Definitions

  • the present invention generally relates to the field of insect repellents, and in particular to an ingestible insect repellant composition, system and method which is safe for ingestion by humans and animals, yet allows for the secretion through the skin of an agent effective in repelling insects.
  • the present invention is for an ingestible insect repellent composition and method utilizing a mixture of vitamins and extracts of lemon, coffee and/or peppermint as active insect deterrent.
  • the composition may be diluted for easier intake into water, juices, milk, soda, mixed drinks and other beverages.
  • Exemplary embodiments disclosed herein may include creating a premix capable of providing up to 100% of the suggested daily intake of specific Vitamin when diluted in any appropriate beverage.
  • Exemplary embodiments may be utilized to repel insects for hours after ingestion in both humans and animals. The exemplary embodiments may provide this repellent without the harmful effects of other chemicals and repellents.
  • the invention comprises an ingestible insect repellent composition
  • a transfer agent representing 90 to over 99% of the composition, said transfer agent being non-toxic to humans and capable of crossing the dermis of humans and similar animals and being secreted as part of the sweating function, and a catalyst group comprised of one or more B-complex vitamins, said catalyst group representing the balance of the totality of the above composition.
  • the transfer agent is comprised of extracts made from lemon, coffee, peppermint leaf, Achillea alpine, alpha-tyerpinene, basil, callicarpa Americana or Beautyberry, Camphor, castor oil, Catnip, cedar oil, celery extract, cinnamon, clove, fennel, garlic, geranium, lavender, lemongrass, marigold, rosemary or thyme.
  • the catalyst group is selected in various percentages from the group comprised by the B-complex vitamins.
  • the catalyst group is comprised of equal portions of Bi and Bi 2 vitamins. In another aspect, the catalyst group is comprised of equal portions of Bi, B 2 and B 6 vitamins. In another aspect, the catalyst group is comprised of equal portions of Bi, B 2 , B 6 and Bi 2 vitamins. In yet another aspect, the proportions of the catalyst group are varies by as much as 50% from one to another. In another aspect, the composition has amounts of Vitamins B 3 , B 5 , B 7 , B 9 and Vitamin C sufficient to meet the recommended USDA minimums for an adult. In yet another aspect, sufficient fluid to dilute said composition into a drinkable mix is added.
  • the invention comprises an ingestible insect repellent for humans or animals comprising blending a transfer agent with one or more components selected from a catalyst group comprised of the B-complex vitamins.
  • the blending transfer agent is selected from the group comprised from the following extracts, lemon, coffee, peppermint leaf, Achillea alpine, alpha-tyerpinene, basil, callicarpa Americana or Beautyberry, Camphor, castor oil, Catnip, cedar oil, celery extract, cinnamon, clove, fennel, garlic, geranium, lavender, lemongrass, marigold, rosemary or thyme.
  • the catalyst group is selected from a group comprised of equal portions of Bi, B 2 , B 6 and Bi 2 vitamins.
  • the proportions of the catalyst group are varies by as much as 50% from one to another.
  • the composition has amounts of Vitamins B 3 , B 5 , B 7 , B 9 and Vitamin C sufficient to meet the recommended USD A minimums for an adult.
  • the catalyst group is selected from a group comprised of the Bi ; B 2 and B 6 vitamins, the Bi and B 2 vitamins.
  • the invention is a method for preparing an ingestible insect repellent for humans or animals comprising blending a transfer agent with one or more components selected from a catalyst group; and ingesting said repellent.
  • FIG. 1 shows an illustration of a transdermal patch in the Pryor Art.
  • the present invention accomplishes an ingestible insect repellent system for humans or other animals capable of sweating or otherwise transferring elements in their bloodstream through their skin, dermis, hide or similar body barrier to the outside. While a deterrent to many insects, such an outgoing transdermal delivery method is particularly effective when fighting mosquitoes and other flying insects that intent to byte their victim's skin.
  • FIG. 1 illustrates such a patch structure, according to the Pryor Art disclosure in Enscore et al (U.S. Pat. No. 4,559,222).
  • patches pass a certain element, component or combination of them through the skin layer, into the bloodstream. In this fashion, medication can be administered to a user externally.
  • the invention described here does the opposite, it takes into the body one or more agents that have been found to have insect repellent qualities, and by combining them with a number of catalysts that facilitate body actions such as circulation, , achieves a formulation that will encourage the transfer of the repellent agent from the user's bloodstream to their skin surface, from where the natural evaporation or sublimation of the agent in the user' s skin provides for its action as a repellent.
  • the transfer agent goes through the skin or dermis (that of the skin allowing various substances to cross it), but in the opposite direction. That is, the user ingests an agent, element, or combination of agents that they will then exude in combination with their perspiration, sweat or other fluid transfer to the skin.
  • This fluid secretion by the skin is common in mammals as a cooling mechanism. Even in some animals with no sweat gland, it is common for fluids to be secreted through their mouth.
  • the disclosed system allows for a non-toxic repellent to be "sweated” (although in reality it the repellent transfer agent mixed with the other common components in sweat that is passed through the dermis and fairly evenly distributed into the skin.
  • a common reaction to sweating is to use the palms of our hands to distribute it along the skin (as well as to say, "phew, its hot", although the latter has no contribution to the repellent action), this spreading of the sweat, does has the effect of coating any area of the body that has not had any repellent coverage, increasing it's effectiveness.
  • the first element the ingestible repellent system requires is a suitable transfer agent (any of a number of substances that are capable of traveling across the dermis from the bloodstream) that is safe to be ingested by the user.
  • This transfer agent(s) must be completely safe to the human or animal performing the ingesting, while at the same time being capable of being exuded through the dermis.
  • This, inside-out, repellent application is primarily accomplished by the transfer agent.
  • the transfer agent may be comprised of one or a combination of the following elements; lemon, coffee or peppermint.
  • Lemon juice is about 5% to 6% (approximately 0.3 M) citric acid, which gives lemons a sour taste, and a pH of 2 to 3. This makes lemon juice an inexpensive, readily available acid for use in educational science experiments.
  • Many lemon-flavored drinks and candies are available, including lemonade and sherbet lemons.
  • the extract of said lemon juice is used, in concentrations of at least 10: 1.
  • Coffee is a brewed drink prepared from roasted seeds, called coffee beans, of the coffee plant. These beans are the seeds of coffee cherries that grow on said tree. Coffee has a stimulant effect, and can have a stimulating effect on humans due to its caffeine content. However, applicant's experiments have shown positive results with both Caffeinated and Decaffeinated coffee extracts. In one embodiment, the extract of said coffee is used in concentrations of at least 10: 1.
  • Peppermint (Menthe x pipe Rita, also known as M. balsa mea Wild) is a hybrid mint, formed from a cross between the water mint (Menthe aquatic) and spearmint (Menthe spiced). It is found wild occasionally with its parent species.
  • Peppermint has a high menthol content, and its oil also contains menthone and menthyl esters, particularly menthyl acetate. Dried peppermint typically has 0.3-0.4% of volatile oil containing menthol (29-48%), menthone (20-31%), menthyl acetate (3-10%), menthofuran (1-7%) and many trace constituents including limonene, pulegone, eucalyptol, and pinene. In one embodiment, the peppermint leaf extract is used in concentrations of at least 10: 1, and as high as 100: 1.
  • Some of the other transfer agents that have been found to be natural insect repellents include; Achillea alpine, alpha-tyerpinene, basil, callicarpa Americana or Beautyberry, Camphor, castor oil, Catnip, cedar oil, celery extract, cinnamon, clove, fennel, garlic, geranium, lavender, lemongrass, marigold, rosemary and thyme.
  • Achillea alpine alpha-tyerpinene
  • basil a callicarpa Americana or Beautyberry
  • Camphor castor oil
  • Catnip cedar oil
  • celery extract cinnamon
  • clove fennel
  • garlic geranium
  • lavender lemon
  • a catalyst group comprised of a combination of B vitamins (also known as B-complex vitamins) would be added to the transfer agent described above.
  • B vitamins are a group of water-soluble vitamins that play important roles in cell metabolism.
  • B vitamins were once thought to be a single vitamin, then referred to as vitamin B. Later research showed that they are chemically distinct vitamins, although they often coexist in the same foods.
  • Supplements containing all eight are referred to as a vitamin B complex, while Individual B vitamin supplements are referred to by the specific name of each vitamin (e.g., Bi, B 2 , B 6 etc.).
  • the transfer agent is combined with one or more B complex catalyst groups, said catalyst groups formed from a combination of individual B vitamins from a group comprised from said vitamin B complex. They have the effect of accelerating the user's metabolism, facilitating the exuding of the transfer agent across the dermis (preferably as part of sweating). In one embodiment, this is done by adding quantities of vitamins Bi (Thiamine), B 2 (Riboflavin), B 6 (Pyridoxine, pyridoxal, or pyridoxamine, or pyridoxine hydrochloride)) and Bi 2 (Cobalamins or Cyanocobalamin).
  • the ratios of transfer agent to catalyst group vitamins (Bi, B 2 , B 6 and/or B 12 ) is in the 1000: 1 to 20000: 1, with a 7000: 1 ratio found to be effective.
  • the selected B complex catalyst group 'encourages' your body to sweat, something fairly common when encountering mosquitoes, which tend to exist in high humidity environments.
  • Various combinations are possible, with the key being an up to 33% variation in a roughly 1750: 1 transfer agent to totality of catalyst group.
  • Various catalyst groups' combinations are possible, with an up to 33% variation on equal parts of Bi, B 2 , B 6 , and Bi 2 .
  • B-complex selection other vitamins and elements may be used to fulfill other human health conditions, such as those comprising, the remaining B-complex members, including B 3 (niacin or niacinamide), B 5 (Pantothenic acidor Calcium d-Pantothenate), B 7 (Biotin) and B 9 (Folic Acid), Vitamin C or Ascorbic Acid, as well as stability agents such as Potassium Sorbate in various ratios.
  • the invention is made into a premix, for mixing with an appropriate carrier.
  • a premix would be optimal when combined with fruit juices (including orange, grapefruit, grape, apple, cranberry, etc.), milk or milk by-products, coffee or tea, soft drinks (carbonated and non-carbonated), water (also carbonated or non-carbonated), sport drinks, and any other human ingestible fluid.
  • the mix is added to a syrup or other mixer intended for use with alcoholic drinks.
  • the mixture is added to a fluid (such as milk or juice) which is then processed using a UHT process.
  • Ultra-high temperature processing (less often) ultra-heat treatment (both abbreviated UHT), or ultra-pasteurization is the sterilization of food by heating it for an extremely short period, around 1-2 seconds, at a temperature exceeding 135°C (275°F), which is the temperature required to kill spores in milk.
  • the most common UHT product is milk, but the process is also used for fruit juices, cream, soy milk, yogurt, wine, and even soups and stews.
  • Composition 1 A premix containing a total of 1850 mg is created, for mixing into an appropriate amount of fluid. Such a premix would contain the following suggested ratios;
  • Such a mixture could be mixed with 240 ml of orange juice, providing a refreshing drink capable of repelling insects for two to six hours or longer, depending on a person's metabolism.
  • Composition Two A premix containing a total of 925 mg is created, for mixing into an appropriate amount of fluid. Such a premix would contain the following suggested ratios;
  • Peppermint Leaf Extract 20: 1 175 mg
  • Vitamin B 6 25 meg
  • Such a mixture could be mixed with 120 ml of milk, put through a UHT process, creating a nutritional minimum drink capable of providing in two servings the USDA recommended nutritional minimums, as well as two to six hours of combined protection.

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Biotechnology (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Botany (AREA)
  • Cosmetics (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Cette invention concerne une composition insectifuge ingérable et un procédé utilisant un mélange de vitamines et d'extraits de citron, de café et/ou de menthe poivrée comme principe actif insectifuge. Ladite composition peut être diluée dans de l'eau, des jus de fruits, du lait, une boisson gazeuse, des mélanges de boissons et d'autres liquides pour faciliter son ingestion. Dans certains modes de réalisation, l'invention peut comprendre une étape consistant à créer un prémélange capable de fournir jusqu'à 100 % des apports nutritionnels quotidiens conseillés d'une vitamine spécifique lorsqu'il est dilué dans une boisson appropriée. Selon certains exemples de modes de réalisation, la composition de l'invention peut être utilisée chez l'homme et l'animal pour repousser les insectes pendant plusieurs heures après son ingestion. Les modes de réalisation de l'invention concernent, donc, un répulsif dépourvu des effets délétères d'autres produits chimiques et répulsifs.
PCT/US2011/031093 2011-04-04 2011-04-04 Composition insectifuge ingérable et système associé Ceased WO2012138320A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/US2011/031093 WO2012138320A1 (fr) 2011-04-04 2011-04-04 Composition insectifuge ingérable et système associé

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PCT/US2011/031093 WO2012138320A1 (fr) 2011-04-04 2011-04-04 Composition insectifuge ingérable et système associé

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108684728A (zh) * 2018-07-27 2018-10-23 郑州兰茜生物工程有限公司 一种安全可食型驱蚊剂及其制备方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040127553A1 (en) * 2002-03-20 2004-07-01 Hallahan David L. Insect repellent compositions comprising dihydronepetalactone
US20040162283A1 (en) * 1998-11-17 2004-08-19 Thomas Goebel Acyclic and cyclic guanidine-and acetamidine derivatives, their preparation and their use as pesticides, esp. as parasiticides
US20090069407A1 (en) * 2007-03-28 2009-03-12 Phero Tech International Inc. Compounds, compositions and methods for repelling blood-feeding arthropods and deterring their landing and feeding
US20090258044A1 (en) * 2008-04-14 2009-10-15 John Mosher Kit for insect bites

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040162283A1 (en) * 1998-11-17 2004-08-19 Thomas Goebel Acyclic and cyclic guanidine-and acetamidine derivatives, their preparation and their use as pesticides, esp. as parasiticides
US20040127553A1 (en) * 2002-03-20 2004-07-01 Hallahan David L. Insect repellent compositions comprising dihydronepetalactone
US20090069407A1 (en) * 2007-03-28 2009-03-12 Phero Tech International Inc. Compounds, compositions and methods for repelling blood-feeding arthropods and deterring their landing and feeding
US20090258044A1 (en) * 2008-04-14 2009-10-15 John Mosher Kit for insect bites

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108684728A (zh) * 2018-07-27 2018-10-23 郑州兰茜生物工程有限公司 一种安全可食型驱蚊剂及其制备方法

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