WO2012165837A3 - 라만 분석 기반 고속 다중 약물 고속 스크리닝 장치 - Google Patents

라만 분석 기반 고속 다중 약물 고속 스크리닝 장치 Download PDF

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Publication number
WO2012165837A3
WO2012165837A3 PCT/KR2012/004223 KR2012004223W WO2012165837A3 WO 2012165837 A3 WO2012165837 A3 WO 2012165837A3 KR 2012004223 W KR2012004223 W KR 2012004223W WO 2012165837 A3 WO2012165837 A3 WO 2012165837A3
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WIPO (PCT)
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speed
screening apparatus
raman
multiple drug
raman analysis
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Ceased
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PCT/KR2012/004223
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English (en)
French (fr)
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WO2012165837A2 (ko
Inventor
서영덕
전기석
김형민
이강택
진승민
남상환
배윤미
이혜미
이경희
박효선
김필환
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Korea Research Institute of Chemical Technology
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Korea Research Institute of Chemical Technology
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Application filed by Korea Research Institute of Chemical Technology filed Critical Korea Research Institute of Chemical Technology
Priority to US14/122,975 priority Critical patent/US9459257B2/en
Priority to JP2014513432A priority patent/JP5917686B2/ja
Priority to CN201280038152.XA priority patent/CN103718038B/zh
Priority to EP12794000.5A priority patent/EP2717052A4/en
Priority to CA2837463A priority patent/CA2837463C/en
Publication of WO2012165837A2 publication Critical patent/WO2012165837A2/ko
Publication of WO2012165837A3 publication Critical patent/WO2012165837A3/ko
Priority to IL229676A priority patent/IL229676A/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • G01N33/587—Nanoparticles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • G01N21/658—Raman scattering enhancement Raman, e.g. surface plasmons
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/36—Microscopes arranged for photographic purposes or projection purposes or digital imaging or video purposes including associated control and data processing arrangements
    • G02B21/365—Control or image processing arrangements for digital or video microscopes
    • G02B21/367—Control or image processing arrangements for digital or video microscopes providing an output produced by processing a plurality of individual source images, e.g. image tiling, montage, composite images, depth sectioning, image comparison
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04N—PICTORIAL COMMUNICATION, e.g. TELEVISION
    • H04N25/00—Circuitry of solid-state image sensors [SSIS]; Control thereof
    • H04N25/70—SSIS architectures; Circuits associated therewith
    • H04N25/71—Charge-coupled device [CCD] sensors; Charge-transfer registers specially adapted for CCD sensors

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Multimedia (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Nanotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Optics & Photonics (AREA)
  • Signal Processing (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)

Abstract

본 발명은 라만 분석 기반 고속 다중 약물 고속 스크리닝 장치에 관한 것으로, 본 발명에 따른 스크리닝 장치는 물질 간에 간섭이 없고 스펙트럼의 피크가 샤프(sharp)하여 다중 검출이 가능한 라만 분광법을 사용하고, 라만 신호를 약 1012배로 증폭시키고 높은 재현성을 나타내는 코어-갭-쉘 나노입자를 이용하여 라만 신호를 용이하게 검출할 수 있으며, 검출기로서 스캐너가 아닌 CCD 카메라를 사용함으로써 시료 내 분자간 이동이 필요 없어 고속으로 다중 스크리닝할 수 있고, 5색 이상의 다중 컬러 코딩이 가능하므로, 각종 약물 스크리닝에 유용하게 사용될 수 있다.
PCT/KR2012/004223 2011-05-29 2012-05-29 라만 분석 기반 고속 다중 약물 고속 스크리닝 장치 Ceased WO2012165837A2 (ko)

Priority Applications (6)

Application Number Priority Date Filing Date Title
US14/122,975 US9459257B2 (en) 2011-05-29 2012-05-29 High-speed screening apparatus for a Raman analysis-based high-speed multiple drug
JP2014513432A JP5917686B2 (ja) 2011-05-29 2012-05-29 ラマン分析基盤高速多重薬物高速スクリーニング装置
CN201280038152.XA CN103718038B (zh) 2011-05-29 2012-05-29 高速的基于拉曼分析的多药物高速筛选装置
EP12794000.5A EP2717052A4 (en) 2011-05-29 2012-05-29 HIGH SPEED SCREENING DEVICE FOR A MULTI AND HIGH SPEED MEDICINE BASED ON RAMAN ANALYZES
CA2837463A CA2837463C (en) 2011-05-29 2012-05-29 High-speed screening apparatus for a raman analysis-based high-speed multiple drug
IL229676A IL229676A (en) 2011-05-29 2013-11-28 Instrument and method are based on Raman analysis for high-speed multidrug screening

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
KR10-2011-0050991 2011-05-29
KR20110050991 2011-05-29
KR1020120056775A KR101361652B1 (ko) 2011-05-29 2012-05-29 라만 분석 기반 고속 다중 약물 고속 스크리닝 장치
KR10-2012-0056775 2012-05-29

Publications (2)

Publication Number Publication Date
WO2012165837A2 WO2012165837A2 (ko) 2012-12-06
WO2012165837A3 true WO2012165837A3 (ko) 2013-02-07

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2012/004223 Ceased WO2012165837A2 (ko) 2011-05-29 2012-05-29 라만 분석 기반 고속 다중 약물 고속 스크리닝 장치

Country Status (8)

Country Link
US (1) US9459257B2 (ko)
EP (1) EP2717052A4 (ko)
JP (1) JP5917686B2 (ko)
KR (1) KR101361652B1 (ko)
CN (1) CN103718038B (ko)
CA (1) CA2837463C (ko)
IL (1) IL229676A (ko)
WO (1) WO2012165837A2 (ko)

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JP7321391B2 (ja) * 2020-03-27 2023-08-04 ジェモロジカル インスティテュート オブ アメリカ インコーポレイテッド（ジーアイエー） ジェムストーン鑑別のための撮像支援走査型分光法
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Publication number Publication date
KR20120132668A (ko) 2012-12-07
CN103718038B (zh) 2016-06-22
US9459257B2 (en) 2016-10-04
CA2837463A1 (en) 2012-12-06
JP2014515496A (ja) 2014-06-30
IL229676A (en) 2016-10-31
JP5917686B2 (ja) 2016-05-18
EP2717052A2 (en) 2014-04-09
US20140113283A1 (en) 2014-04-24
KR101361652B1 (ko) 2014-02-14
WO2012165837A2 (ko) 2012-12-06
IL229676A0 (en) 2014-01-30
CA2837463C (en) 2016-08-09
CN103718038A (zh) 2014-04-09
EP2717052A4 (en) 2014-10-29

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