|
US6849257B2
(en)
|
2000-02-04 |
2005-02-01 |
Children's Hospital Research Foundation |
Lipid hydrolysis therapy for atherosclerosis and related diseases
|
|
SG171879A1
(en)
|
2008-12-03 |
2011-07-28 |
Marina Biotech Inc |
Usirna complexes
|
|
US8835358B2
(en)
|
2009-12-15 |
2014-09-16 |
Cellular Research, Inc. |
Digital counting of individual molecules by stochastic attachment of diverse labels
|
|
FI3205351T3
(fi)
|
2010-04-23 |
2023-07-06 |
Alexion Pharma Inc |
Lysosomaalisen kertymätaudin entsyymi
|
|
KR20150038636A
(ko)
|
2010-09-09 |
2015-04-08 |
시나게바 바이오파르마, 코포레이션 |
환자에서 리소좀 산 리파제 결핍증의 치료를 위한 리소좀 산 리파제의 용도
|
|
WO2012112681A1
(fr)
|
2011-02-15 |
2012-08-23 |
Shire Human Genetic Therapies, Inc. |
Procédés de traitement d'un déficit en lipase acide lysosomale
|
|
WO2013120003A1
(fr)
|
2012-02-08 |
2013-08-15 |
Isis Pharmaceuticals, Inc. |
Modulation d'arn par ciblage de répétition
|
|
CA2865575C
(fr)
|
2012-02-27 |
2024-01-16 |
Cellular Research, Inc. |
Compositions et trousses pour le comptage moleculaire
|
|
EP2831232A4
(fr)
|
2012-03-30 |
2015-11-04 |
Univ Washington |
Procédés de modulation de l'expression de tau pour réduire l'avc et modifier un symptôme neurodégénératif
|
|
IL288931B2
(en)
|
2013-03-14 |
2025-05-01 |
Alnylam Pharmaceuticals Inc |
Compositions comprising a complementary portion of C5 IRNA and methods of using them
|
|
CN105264091B
(zh)
|
2013-03-14 |
2020-02-28 |
Ionis制药公司 |
用于调节tau表达的组合物和方法
|
|
DK2992098T3
(da)
|
2013-05-01 |
2019-06-17 |
Ionis Pharmaceuticals Inc |
Sammensætninger og fremgangsmåder til modulering af hbv- og ttr-ekspression
|
|
TW202246503A
(zh)
|
2013-07-19 |
2022-12-01 |
美商百健Ｍａ公司 |
用於調節τ蛋白表現之組合物
|
|
KR102758333B1
(ko)
|
2013-08-28 |
2025-01-23 |
벡톤 디킨슨 앤드 컴퍼니 |
대량의 동시 단일 세포 분석
|
|
EP3119888B1
(fr)
|
2014-03-19 |
2021-07-28 |
Ionis Pharmaceuticals, Inc. |
Compositions permettant de moduler l'expression de l'ataxine 2
|
|
BR112016022711A2
(pt)
*
|
2014-04-01 |
2017-10-31 |
Monsanto Technology Llc |
composições e métodos para controle de pragas de inseto
|
|
CN106459975B
(zh)
|
2014-05-23 |
2020-03-27 |
建新公司 |
肽载体上的多个寡核苷酸部分
|
|
US10533172B2
(en)
|
2014-09-18 |
2020-01-14 |
The University Of British Columbia |
Allele-specific therapy for huntington disease haplotypes
|
|
CA2976445A1
(fr)
|
2015-02-13 |
2016-08-18 |
Alnylam Pharmaceuticals, Inc. |
Compositions d'arni du gene codant pour la proteine 3 contenant un domaine phospholipase de type patatine (pnpla3) et leurs procedes d'utilisation
|
|
WO2016160844A2
(fr)
|
2015-03-30 |
2016-10-06 |
Cellular Research, Inc. |
Procédés et compositions pour codage à barres combinatoire
|
|
JP6940484B2
(ja)
|
2015-09-11 |
2021-09-29 |
セルラー リサーチ， インコーポレイテッド |
ライブラリー正規化のための方法および組成物
|
|
EP3387129A1
(fr)
*
|
2015-12-10 |
2018-10-17 |
Alnylam Pharmaceuticals, Inc. |
COMPOSITIONS D'ARNi CHAPERON (SCAP) DE LA PROTÉINE SREBP (STEROL REGULATORY ELEMENT BINDING PROTEIN), ET PROCÉDÉS D'UTILISATION ASSOCIÉS
|
|
AU2016381174A1
(en)
|
2015-12-31 |
2018-05-31 |
Ionis Pharmaceuticals, Inc. |
Methods for reducing Ataxin-2 expression
|
|
WO2017156242A1
(fr)
|
2016-03-09 |
2017-09-14 |
Ionis Pharmaceuticals, Inc. |
Procédés et compositions pour inhiber l'expression de pmp22
|
|
US10301677B2
(en)
|
2016-05-25 |
2019-05-28 |
Cellular Research, Inc. |
Normalization of nucleic acid libraries
|
|
US10202641B2
(en)
|
2016-05-31 |
2019-02-12 |
Cellular Research, Inc. |
Error correction in amplification of samples
|
|
US10640763B2
(en)
|
2016-05-31 |
2020-05-05 |
Cellular Research, Inc. |
Molecular indexing of internal sequences
|
|
UY37376A
(es)
*
|
2016-08-26 |
2018-03-23 |
Amgen Inc |
Construcciones de arni para inhibir expresión de asgr1 y métodos para su uso
|
|
CN109791157B
(zh)
|
2016-09-26 |
2022-06-07 |
贝克顿迪金森公司 |
使用具有条形码化的寡核苷酸序列的试剂测量蛋白质表达
|
|
HUE065170T2
(hu)
|
2016-09-29 |
2024-05-28 |
Biogen Ma Inc |
Vegyületek és módszerek a TAU expresszió csökkentésére
|
|
CA3041761A1
(fr)
*
|
2016-10-31 |
2018-05-03 |
Gifu University |
Molecule d'acide nucleique double brin, et son utilisation
|
|
CN110382708A
(zh)
|
2017-02-01 |
2019-10-25 |
赛卢拉研究公司 |
使用阻断性寡核苷酸进行选择性扩增
|
|
CA3051839A1
(fr)
|
2017-02-17 |
2018-08-23 |
Bristol-Myers Squibb Company |
Anticorps anti-alpha-synucleine et leurs utilisations
|
|
JOP20190215A1
(ar)
*
|
2017-03-24 |
2019-09-19 |
Ionis Pharmaceuticals Inc |
مُعدّلات التعبير الوراثي عن pcsk9
|
|
NO344051B1
(en)
*
|
2017-05-04 |
2019-08-26 |
Patogen As |
Novel virus in Fish and Method for detection
|
|
WO2018217975A1
(fr)
*
|
2017-05-24 |
2018-11-29 |
The Regents Of The University Of California |
Thérapies antisens pour le traitement du cancer
|
|
CN110719959B
(zh)
|
2017-06-05 |
2021-08-06 |
贝克顿迪金森公司 |
针对单细胞的样品索引
|
|
JP7095910B2
(ja)
*
|
2017-08-25 |
2022-07-05 |
ザ ガヴァーニング カウンシル オブ ザ ユニヴァーシティ オブ トロント |
インスリン抵抗性を検出し治療するための組成物および方法
|
|
BR112020018094A2
(pt)
|
2018-03-08 |
2020-12-22 |
Incyte Corporation |
Compostos de aminopirazina diol como inibidores de pi3k-¿
|
|
EP3775211B1
(fr)
*
|
2018-04-12 |
2023-04-05 |
MiNA Therapeutics Limited |
Compositions
|
|
CN112272710A
(zh)
|
2018-05-03 |
2021-01-26 |
贝克顿迪金森公司 |
高通量多组学样品分析
|
|
JP7358388B2
(ja)
|
2018-05-03 |
2023-10-10 |
ベクトン・ディキンソン・アンド・カンパニー |
反対側の転写物末端における分子バーコーディング
|
|
CN112218950A
(zh)
*
|
2018-06-13 |
2021-01-12 |
第一三共株式会社 |
心肌损伤治疗药
|
|
US11046658B2
(en)
|
2018-07-02 |
2021-06-29 |
Incyte Corporation |
Aminopyrazine derivatives as PI3K-γ inhibitors
|
|
AR115847A1
(es)
|
2018-07-25 |
2021-03-03 |
Ionis Pharmaceuticals Inc |
Compuestos y métodos para reducir la expresión de la atxn2
|
|
WO2020056170A1
(fr)
*
|
2018-09-12 |
2020-03-19 |
Fred Hutchinson Cancer Research Center |
Réduction de l'expression de cd33 pour protéger sélectivement des cellules thérapeutiques
|
|
ES2992135T3
(es)
|
2018-10-01 |
2024-12-09 |
Becton Dickinson Co |
Determinar secuencias de transcripción 5
|
|
US11932849B2
(en)
|
2018-11-08 |
2024-03-19 |
Becton, Dickinson And Company |
Whole transcriptome analysis of single cells using random priming
|
|
US11492660B2
(en)
|
2018-12-13 |
2022-11-08 |
Becton, Dickinson And Company |
Selective extension in single cell whole transcriptome analysis
|
|
JP7561129B2
(ja)
*
|
2018-12-21 |
2024-10-03 |
アイオーニス ファーマシューティカルズ， インコーポレーテッド |
Ｐｍｐ２２の発現を低減するための化合物及び方法
|
|
SG11202106857VA
(en)
*
|
2018-12-28 |
2021-07-29 |
Dicerna Pharmaceuticals Inc |
Compositions and methods for inhibiting hmgb1 expression
|
|
ES2945227T3
(es)
|
2019-01-23 |
2023-06-29 |
Becton Dickinson Co |
Oligonucleótidos asociados con anticuerpos
|
|
WO2020167920A1
(fr)
|
2019-02-14 |
2020-08-20 |
Cellular Research, Inc. |
Amplification de transcriptome entier et ciblé hybride
|
|
FI3938542T3
(fi)
*
|
2019-03-13 |
2025-10-03 |
Goodgut S L |
Parannettu menetelmä pitkälle edenneen paksu- ja peräsuolikasvaimen, pitkälle edenneen adenooman ja/tai paksu- ja peräsuolisyövän seulomiseksi, diagnosoimiseksi ja/tai seuraamiseksi
|
|
CN111718929B
(zh)
*
|
2019-03-20 |
2022-10-18 |
中国科学院上海营养与健康研究所 |
利用环形rna进行蛋白翻译及其应用
|
|
EP3976010A4
(fr)
*
|
2019-06-03 |
2023-08-02 |
Quralis Corporation |
Oligonucléotides et leurs méthodes d'utilisation pour traiter des affections neurologiques
|
|
CN120099137A
(zh)
|
2019-07-22 |
2025-06-06 |
贝克顿迪金森公司 |
单细胞染色质免疫沉淀测序测定
|
|
JP7522189B2
(ja)
|
2019-11-08 |
2024-07-24 |
ベクトン・ディキンソン・アンド・カンパニー |
免疫レパートリーシーケンシングのための完全長ｖ（ｄ）ｊ情報を得るためのランダムプライミングの使用
|
|
US12565653B2
(en)
|
2019-11-22 |
2026-03-03 |
Alnylam Pharmaceuticals, Inc. |
ATAXIN3 (ATXN3) RNAi agent compositions and methods of use thereof
|
|
EP4077666A1
(fr)
|
2019-12-16 |
2022-10-26 |
Alnylam Pharmaceuticals, Inc. |
Compositions d'arni du gène codant pour la protéine 3 contenant un domaine phospholipase de type patatine (pnpla3) et leurs méthodes d'utilisation
|
|
WO2021146219A1
(fr)
|
2020-01-13 |
2021-07-22 |
Becton, Dickinson And Company |
Capture de cellules à l'aide d'oligonucléotides contenant de la du
|
|
US11649497B2
(en)
|
2020-01-13 |
2023-05-16 |
Becton, Dickinson And Company |
Methods and compositions for quantitation of proteins and RNA
|
|
WO2021155057A1
(fr)
|
2020-01-29 |
2021-08-05 |
Becton, Dickinson And Company |
Puits à code-barres pour la cartographie spatiale de cellules individuelles par séquençage
|
|
EP3868884A1
(fr)
*
|
2020-02-19 |
2021-08-25 |
Aarhus Universitet |
Procédé de sous-typage du cancer de la vessie à l'aide d'aptamères
|
|
WO2021173719A1
(fr)
|
2020-02-25 |
2021-09-02 |
Becton, Dickinson And Company |
Sondes bi-spécifiques permettant l'utilisation d'échantillons monocellulaires en tant que contrôle de compensation de couleur unique
|
|
US20230313185A1
(en)
*
|
2020-05-08 |
2023-10-05 |
Triplet Therapeutics, Inc. |
Methods for the treatment of nucleotide repeat expansion disorders associated with msh3 activity
|
|
US11661625B2
(en)
|
2020-05-14 |
2023-05-30 |
Becton, Dickinson And Company |
Primers for immune repertoire profiling
|
|
US12157913B2
(en)
|
2020-06-02 |
2024-12-03 |
Becton, Dickinson And Company |
Oligonucleotides and beads for 5 prime gene expression assay
|
|
AR122534A1
(es)
|
2020-06-03 |
2022-09-21 |
Triplet Therapeutics Inc |
Métodos para el tratamiento de los trastornos de expansión por repetición de nucleótidos asociados con la actividad de msh3
|
|
EP4165185A4
(fr)
*
|
2020-06-11 |
2025-09-10 |
Genetic Intelligence Inc New York Ny |
Compositions de modulation du gène flcn et procédés associés
|
|
US11932901B2
(en)
|
2020-07-13 |
2024-03-19 |
Becton, Dickinson And Company |
Target enrichment using nucleic acid probes for scRNAseq
|
|
US12391940B2
(en)
|
2020-07-31 |
2025-08-19 |
Becton, Dickinson And Company |
Single cell assay for transposase-accessible chromatin
|
|
EP4247967A1
(fr)
|
2020-11-20 |
2023-09-27 |
Becton, Dickinson and Company |
Profilage de protéines hautement exprimées et faiblement exprimées
|
|
CN116685850A
(zh)
|
2020-12-15 |
2023-09-01 |
贝克顿迪金森公司 |
单细胞分泌组分析
|
|
IL282597B
(en)
*
|
2021-04-22 |
2022-08-01 |
B G Negev Technologies And Applications Ltd At Ben Gurion Univ |
Birds for producing female hatchling and methods of producing same
|
|
US20250243492A1
(en)
*
|
2021-10-04 |
2025-07-31 |
Atalanta Therapeutics, Inc. |
Compositions and methods for treatment of prion diseases
|
|
CA3234383A1
(fr)
*
|
2021-10-15 |
2023-04-27 |
Codexis, Inc. |
Variants de desoxynucleotidyl transferase terminale modifiee
|
|
GB202117593D0
(en)
*
|
2021-12-06 |
2022-01-19 |
Royal Veterinary College |
Methods
|
|
AU2023250231A1
(en)
*
|
2022-04-08 |
2024-10-31 |
Scineuro Therapeutics Inc. |
Oligonucleotide for reducing the expression of leucine-rich repeat kinase 2 (lrrk2) and its use for preventing and/or treating human diseases
|
|
CN120225673A
(zh)
|
2022-06-01 |
2025-06-27 |
e-生物有限公司 |
表达和/或功能抑制剂
|
|
CN115813944A
(zh)
*
|
2022-07-01 |
2023-03-21 |
青岛市中心医院 |
一种具有血管新生功效的制剂
|
|
EP4562146A2
(fr)
*
|
2022-07-27 |
2025-06-04 |
E-Therapeutics plc |
Composés d'acide nucléique
|
|
WO2024023267A2
(fr)
*
|
2022-07-27 |
2024-02-01 |
E-Therapeutics Plc |
Composés d'acides nucléiques
|
|
WO2024039776A2
(fr)
*
|
2022-08-18 |
2024-02-22 |
Alnylam Pharmaceuticals, Inc. |
Compositions d'arnsi universelles ne ciblant pas et procédés d'utilisation associés
|
|
WO2024165568A2
(fr)
*
|
2023-02-06 |
2024-08-15 |
E-Therapeutics Plc |
Inhibiteurs d'expression et/ou de fonction
|
|
AU2024308906A1
(en)
|
2023-06-30 |
2026-02-05 |
Atrium Therapeutics, Inc. |
Compositions and methods of using pln-targeting antibody-oligonucleotide conjugates
|
|
CN120082549B
(zh)
*
|
2024-08-22 |
2025-11-07 |
中国科学院动物研究所 |
一种通过靶向病毒小rna抑制水稻病毒复制的方法
|