WO2013060480A3 - Vorrichtung und verfahren zur kontrolle eines volumens einer probe - Google Patents

Vorrichtung und verfahren zur kontrolle eines volumens einer probe Download PDF

Info

Publication number
WO2013060480A3
WO2013060480A3 PCT/EP2012/004524 EP2012004524W WO2013060480A3 WO 2013060480 A3 WO2013060480 A3 WO 2013060480A3 EP 2012004524 W EP2012004524 W EP 2012004524W WO 2013060480 A3 WO2013060480 A3 WO 2013060480A3
Authority
WO
WIPO (PCT)
Prior art keywords
sample
interface
marking
inspecting
volume
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2012/004524
Other languages
English (en)
French (fr)
Other versions
WO2013060480A2 (de
Inventor
Torsten Matthias
Hans-Peter Schimon
Jens BLECKEN
Markus Wulf
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE102011117310A external-priority patent/DE102011117310B4/de
Application filed by Individual filed Critical Individual
Priority to ES12794176T priority Critical patent/ES2899683T3/es
Priority to US14/354,782 priority patent/US9734420B2/en
Priority to EP12794176.3A priority patent/EP2771698B1/de
Priority to PL12794176T priority patent/PL2771698T3/pl
Publication of WO2013060480A2 publication Critical patent/WO2013060480A2/de
Publication of WO2013060480A3 publication Critical patent/WO2013060480A3/de
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01F—MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
    • G01F23/00—Indicating or measuring liquid level or level of fluent solid material, e.g. indicating in terms of volume or indicating by means of an alarm
    • G01F23/22—Indicating or measuring liquid level or level of fluent solid material, e.g. indicating in terms of volume or indicating by means of an alarm by measuring physical variables, other than linear dimensions, pressure or weight, dependent on the level to be measured, e.g. by difference of heat transfer of steam or water
    • G01F23/28—Indicating or measuring liquid level or level of fluent solid material, e.g. indicating in terms of volume or indicating by means of an alarm by measuring physical variables, other than linear dimensions, pressure or weight, dependent on the level to be measured, e.g. by difference of heat transfer of steam or water by measuring the variations of parameters of electromagnetic or acoustic waves applied directly to the liquid or fluent solid material
    • G01F23/284—Electromagnetic waves
    • G01F23/292—Light, e.g. infrared or ultraviolet
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
    • G01N35/1016—Control of the volume dispensed or introduced
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/0002—Inspection of images, e.g. flaw detection
    • G06T7/0012—Biomedical image inspection
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
    • G01N2035/1025—Fluid level sensing

Landscapes

  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Electromagnetism (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Fluid Mechanics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Thermal Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Theoretical Computer Science (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Quality & Reliability (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Length Measuring Devices By Optical Means (AREA)

Abstract

Die vorliegende Erfindung betrifft eine Vorrichtung (120) zur Kontrolle eines Volumens einer Probe (4), wobei die Vorrichtung eine Pipette (1) umfasst, in der zwischen der Probe (4) und einem an die Probe (4) angrenzenden ersten Fluid (6) eine Grenzfläche ausgebildet ist, die außerhalb der Pipette (1) als im Wesentlichen horizontal verlaufende Grenzlinie (4a) zwischen der Probe (4) und dem ersten Fluid (6) optisch wahrnehmbar ist. Weiter umfasst die Vorrichtung eine Kamera (10) mit einer Markierung (15), die in einem Bildfeld der Kamera (10) derart angeordnet ist, dass auf einem aufgenommenen Bild (12) die Grenzlinie (4a) und die Markierung (15) abgebildet werden können. Schließlich umfasst die Vorrichtung (120) eine Auswerteeinrichtung (101), mit der auswertbar ist, ob in dem aufgenommenen Bild die Markierung (15) auf Höhe der Grenzlinie (4a) liegt.
PCT/EP2012/004524 2011-10-28 2012-10-29 Vorrichtung und verfahren zur kontrolle eines volumens einer probe Ceased WO2013060480A2 (de)

Priority Applications (4)

Application Number Priority Date Filing Date Title
ES12794176T ES2899683T3 (es) 2011-10-28 2012-10-29 Dispositivo y procedimiento para controlar el volumen de una muestra
US14/354,782 US9734420B2 (en) 2011-10-28 2012-10-29 Device and method for inspecting a volume of a sample
EP12794176.3A EP2771698B1 (de) 2011-10-28 2012-10-29 Vorrichtung und verfahren zur kontrolle eines volumens einer probe
PL12794176T PL2771698T3 (pl) 2011-10-28 2012-10-29 Urządzenie i sposób kontroli objętości próbki

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE102011117310A DE102011117310B4 (de) 2011-10-28 2011-10-28 Vorrichtung und Verfahren zur Kontrolle eines Volumens einer Probe
DE102011117310.6 2011-10-28
EP2012004488 2012-10-26
EPPCT/EP2012/004488 2012-10-26

Publications (2)

Publication Number Publication Date
WO2013060480A2 WO2013060480A2 (de) 2013-05-02
WO2013060480A3 true WO2013060480A3 (de) 2013-08-15

Family

ID=48168679

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2012/004524 Ceased WO2013060480A2 (de) 2011-10-28 2012-10-29 Vorrichtung und verfahren zur kontrolle eines volumens einer probe

Country Status (3)

Country Link
US (1) US9734420B2 (de)
ES (1) ES2899683T3 (de)
WO (1) WO2013060480A2 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013060482A1 (de) 2011-10-28 2013-05-02 Torsten Matthias Vorrichtung und verfahren zum nachweis von in biologischen oder chemischen proben vorliegenden substanzen
US11183284B2 (en) 2015-06-01 2021-11-23 Digital Hospital, Inc. Dosage confirmation apparatus
WO2017186705A1 (en) * 2016-04-27 2017-11-02 Ventana Medical Systems, Inc. System and method for real-time volume control
EP3482170B1 (de) * 2016-07-08 2020-02-12 Roche Diagnostics GmbH Laborautomatisierungssystem und verfahren zum pipettieren einer laborprobe
EP3944144A1 (de) 2016-10-28 2022-01-26 Beckman Coulter, Inc. System zur beurteilung eines substanzpräparats
JP6437985B2 (ja) * 2016-11-16 2018-12-12 オカノ電機株式会社 分注装置
CN110573886B (zh) * 2017-03-28 2023-08-22 环球生物研究株式会社 测光分注喷嘴组件、测光分注装置及测光分注处理方法
JP7084581B2 (ja) * 2018-07-17 2022-06-15 国立大学法人神戸大学 固液界面検出装置及びこれを備えた前処理装置
US12226776B2 (en) 2021-11-04 2025-02-18 Instrumentation Laboratory Company Preparing substances in a medical diagnostic system

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999042841A1 (de) * 1998-02-20 1999-08-26 Scil Diagnostics Gmbh Analysesystem
DE10215270A1 (de) * 2002-04-06 2003-10-30 Bosch Gmbh Robert Verfahren zur Messung eines Meniskusvolumens oder einer Meniskushöhe eines Flüssigkeitströpfchens
US20070021929A1 (en) * 2000-01-07 2007-01-25 Transform Pharmaceuticals, Inc. Computing methods for control of high-throughput experimental processing, digital analysis, and re-arraying comparative samples in computer-designed arrays
US20090280572A1 (en) * 2008-05-12 2009-11-12 Torsten Matthias Analysis device
EP2133668A1 (de) * 2008-06-12 2009-12-16 CSL Behring GmbH Zerstörungsfreie Messung des Füllvolumens eines mit einer Flüssigkeit gefüllten Behälters

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6388750B1 (en) * 1998-12-17 2002-05-14 Beckman Coulter, Inc. Device and method for preliminary testing a neat serum sample in a primary collection tube
US7185551B2 (en) * 2003-05-22 2007-03-06 Schwartz H Donald Pipetting module
US7876935B2 (en) * 2006-01-30 2011-01-25 Protedyne Corporation Sample processing apparatus with a vision system

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999042841A1 (de) * 1998-02-20 1999-08-26 Scil Diagnostics Gmbh Analysesystem
US20070021929A1 (en) * 2000-01-07 2007-01-25 Transform Pharmaceuticals, Inc. Computing methods for control of high-throughput experimental processing, digital analysis, and re-arraying comparative samples in computer-designed arrays
DE10215270A1 (de) * 2002-04-06 2003-10-30 Bosch Gmbh Robert Verfahren zur Messung eines Meniskusvolumens oder einer Meniskushöhe eines Flüssigkeitströpfchens
US20090280572A1 (en) * 2008-05-12 2009-11-12 Torsten Matthias Analysis device
EP2133668A1 (de) * 2008-06-12 2009-12-16 CSL Behring GmbH Zerstörungsfreie Messung des Füllvolumens eines mit einer Flüssigkeit gefüllten Behälters

Also Published As

Publication number Publication date
US20140320632A1 (en) 2014-10-30
WO2013060480A2 (de) 2013-05-02
US9734420B2 (en) 2017-08-15
ES2899683T3 (es) 2022-03-14

Similar Documents

Publication Publication Date Title
WO2013060480A3 (de) Vorrichtung und verfahren zur kontrolle eines volumens einer probe
EP1924827A4 (de) System und verfahren zur messung des flüssigkeitsstands durch bild
EP2800061A3 (de) Überwachungsverfahren und Augmented Reality System
EP2713596A3 (de) Bildbeurteilungsvorrichtung, Bildbeurteilungsverfahren und Programmspeichermedium
FR2986617B1 (fr) Dispositif et procede pour effectuer des mesures hematologiques et biochimiques a partir d'un echantillon biologique
WO2012154320A8 (en) System and method for detecting and repairing defects in an electrochromic device using thermal imaging
EP2419717A4 (de) Fluoreszenzsensor, fluoreszenzsensor in nadelform und analytmessverfahren
EP2904376A4 (de) Optischer sensor zum nachweis von analyten
EP2713597A3 (de) Bildbeurteilungsvorrichtung, Bildbeurteilungsverfahren und Programmspeichermedium
EP2518465A3 (de) Leckageerkennung
EP2411793A4 (de) Vorrichtung für den nachweis eines analyts
EP2902790A4 (de) Probenfördervorrichtung und automatisiertes system zur probenuntersuchung
WO2013190327A3 (en) Heterogeneous fluid sample characterization
EP2668370A2 (de) Verfahren und vorrichtung zur beurteilung der kontamination einer flüssigkeitsprobe mit mehreren sensoren
BRPI0902903A2 (pt) método de avaliação de sinal e aparelho de avaliação de sinal
EP2912603A4 (de) Automatisierte sichtprüfungsvorrichtung für granulierte proben
BRPI1008574A2 (pt) método de processar imagens de vídeo, aparelho de processamento de imagem de vídeo, e meio de gravação legível por computador
EP2846537A4 (de) Bildsensor und steuerverfahren für bildsensor
EP2665039A3 (de) Detektion des Cameranahfeld Hindernises
WO2013151421A8 (en) Integrated optical and charged particle inspection apparatus
EP2847569A4 (de) Systeme und verfahren zur inspektion von kontaktlinsen
DE602006013404D1 (de) Universelle Schnittstelle zur Registrierung von Bildern
FR2994740B1 (fr) Procede de compensation du vieillissement d'un reactif lors de mesures de fluorescence sur des particules, et dispositif d'analyse biologique mettant en œuvre le procede.
EP2300834A4 (de) Sensorkabel für elektromagnetische überwachung
EP2281186A4 (de) Vorrichtung und verfahren zur optischen messung einer analytkonzentration in einer erythrozytenhaltigen flüssigkeit

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 14354782

Country of ref document: US

WWE Wipo information: entry into national phase

Ref document number: 2012794176

Country of ref document: EP

121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 12794176

Country of ref document: EP

Kind code of ref document: A2