WO2013117751A3 - Méthodes liées au traitement des maladies inflammatoires - Google Patents

Méthodes liées au traitement des maladies inflammatoires Download PDF

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Publication number
WO2013117751A3
WO2013117751A3 PCT/EP2013/052629 EP2013052629W WO2013117751A3 WO 2013117751 A3 WO2013117751 A3 WO 2013117751A3 EP 2013052629 W EP2013052629 W EP 2013052629W WO 2013117751 A3 WO2013117751 A3 WO 2013117751A3
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WO
WIPO (PCT)
Prior art keywords
disorders
treatment
inflammatory diseases
methods related
inflammatory
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2013/052629
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English (en)
Other versions
WO2013117751A2 (fr
Inventor
Klaus Steensgaard FREDERIKSEN
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk AS
Original Assignee
Novo Nordisk AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk AS filed Critical Novo Nordisk AS
Priority to KR1020147022156A priority Critical patent/KR20140124767A/ko
Priority to BR112014019274A priority patent/BR112014019274A2/pt
Priority to EP13704081.2A priority patent/EP2812445A2/fr
Priority to CN201380019432.0A priority patent/CN104204230A/zh
Priority to AU2013217940A priority patent/AU2013217940A1/en
Priority to CA2864133A priority patent/CA2864133A1/fr
Priority to MX2014009490A priority patent/MX2014009490A/es
Publication of WO2013117751A2 publication Critical patent/WO2013117751A2/fr
Publication of WO2013117751A3 publication Critical patent/WO2013117751A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Cette invention concerne des marqueurs génétiques associés avec une méthode de prédiction de la réponse clinique à un traitement anti-inflammatoire chez un patient souffrant d'une maladie inflammatoire.
PCT/EP2013/052629 2012-02-10 2013-02-11 Méthodes liées au traitement des maladies inflammatoires Ceased WO2013117751A2 (fr)

Priority Applications (7)

Application Number Priority Date Filing Date Title
KR1020147022156A KR20140124767A (ko) 2012-02-10 2013-02-11 염증성 질환 및 장애의 치료에 관한 방법
BR112014019274A BR112014019274A2 (pt) 2012-02-10 2013-02-11 métodos relacionados ao tratamento de doenças e distúrbios inflamatórios
EP13704081.2A EP2812445A2 (fr) 2012-02-10 2013-02-11 Méthodes liées au traitement des maladies inflammatoires
CN201380019432.0A CN104204230A (zh) 2012-02-10 2013-02-11 治疗炎性疾病和病症的相关方法
AU2013217940A AU2013217940A1 (en) 2012-02-10 2013-02-11 Methods related to treatment of inflammatory diseases and disorders
CA2864133A CA2864133A1 (fr) 2012-02-10 2013-02-11 Methodes liees au traitement des maladies inflammatoires
MX2014009490A MX2014009490A (es) 2012-02-10 2013-02-11 Metodos relacionados con el tratamiento de enfermedades y trastornos inflamatorios.

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP12154917 2012-02-10
EP12154917.4 2012-02-10
US201261597924P 2012-02-13 2012-02-13
US61/597,924 2012-02-13

Publications (2)

Publication Number Publication Date
WO2013117751A2 WO2013117751A2 (fr) 2013-08-15
WO2013117751A3 true WO2013117751A3 (fr) 2013-10-03

Family

ID=48948117

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2013/052629 Ceased WO2013117751A2 (fr) 2012-02-10 2013-02-11 Méthodes liées au traitement des maladies inflammatoires

Country Status (8)

Country Link
EP (1) EP2812445A2 (fr)
KR (1) KR20140124767A (fr)
CN (1) CN104204230A (fr)
AU (1) AU2013217940A1 (fr)
BR (1) BR112014019274A2 (fr)
CA (1) CA2864133A1 (fr)
MX (1) MX2014009490A (fr)
WO (1) WO2013117751A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20230003433A (ko) 2016-05-20 2023-01-05 세다르스-신나이 메디칼 센터 유전자에 기반한 염증성 장 질환의 진단
CN110244053B (zh) * 2019-05-09 2022-03-11 北京大学第三医院（北京大学第三临床医学院） 用于诊断狼疮肾炎并肺动脉高压疾病的分子标志物及其用途

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007006858A2 (fr) * 2005-07-12 2007-01-18 Oy Jurilab Ltd Methode de traitement de maladies cardio-vasculaires et du metabolisme et detection des risques associes
WO2008048986A2 (fr) * 2006-10-17 2008-04-24 Children's Hospital Medical Center Technique par batterie de gènes pour prédire la réponse dans les maladies intestinales inflammatoires
WO2008104608A1 (fr) * 2007-03-01 2008-09-04 Universite Catholique De Louvain Procédé pour la détermination et la classification de conditions rhumatismales
WO2008157282A1 (fr) * 2007-06-18 2008-12-24 Genentech, Inc. Marqueurs biologiques prédictifs d'une réponse d'arthrite rhumatoïde à des antagonistes de cellule b
WO2010113096A1 (fr) * 2009-03-30 2010-10-07 Tel Hashomer Medical Research Infrastructure And Services Ltd. Méthodes pour prévoir l'évolution clinique de la sclérose en plaque et la traiter
US20110091457A1 (en) * 2009-10-16 2011-04-21 Cornelis Lammert Verweij Method for prognosticating the clinical response of a patient to b-lymphocyte inhibiting or depleting therapy
WO2011154139A2 (fr) * 2010-06-07 2011-12-15 Roche Diagnostics Gmbh Marqueurs d'expression génique pour la prédiction d'une réponse à un traitement par un médicament anticorps monoclonal inhibant le récepteur de l'interleukine-6

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ES2387394T3 (es) 1999-12-23 2012-09-21 Zymogenetics, Inc. Procedimiento de tratamiento de la inflamación
DE10227527A1 (de) 2002-06-20 2004-01-08 Clariant Gmbh Verfahren zur Herstellung von Disazopigmenten
US7435800B2 (en) 2003-05-23 2008-10-14 Chi-Mei Medical Center Antibodies to interleukin-20 and method for inhibiting interleukin-20 induced cell proliferation
EP1697418A2 (fr) 2003-11-21 2006-09-06 ZymoGenetics, Inc. Anticorps du recepteur anti-il-20 et partenaires de liaison et procedes d'utilisation dans l'inflammation
IES20050495A2 (en) 2005-07-20 2006-11-01 Minroc Techn Promotions Ltd A drill bit assembly for fluid-operated percussion drill tools
WO2007038501A2 (fr) 2005-09-27 2007-04-05 The Feinstein Institute For Medical Research Marqueurs de l'arthrite rhumatoide
WO2007081465A2 (fr) 2005-12-09 2007-07-19 Chi-Mei Medical Center Anticorps dirigés contre l'interleukine 20 et procédé d'inhibition de la prolifération cellulaire induite par l'interleukine 20
EP1857559A1 (fr) 2006-05-16 2007-11-21 INSERM (Institut National de la Santé et de la Recherche Médicale) Méthode de prédiction de la réponse aux agents de blocage de TNF aplha
CA2668955A1 (fr) 2006-11-09 2008-05-15 Institut National De La Sante Et De La Recherche Medicale (Inserm) Procede permettant de predire la sensibilite therapeutique a des agents bloquant le tnf-alpha
WO2008132176A2 (fr) 2007-04-27 2008-11-06 Universite Catholique De Louvain Méthode de prévision de la réponse d'un patient à une thérapie bloquant le tnf
SG182183A1 (en) 2007-06-08 2012-07-30 Biogen Idec Inc Biomarkers for predicting anti-tnf responsiveness or non-responsiveness
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KR20110048536A (ko) 2008-08-28 2011-05-11 와이어쓰 엘엘씨 자가면역 질병에서 ｉｌ－２２, ｉｌ－１７ 및 ｉｌ－１ 패밀리 시토킨의 용도
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WO2007006858A2 (fr) * 2005-07-12 2007-01-18 Oy Jurilab Ltd Methode de traitement de maladies cardio-vasculaires et du metabolisme et detection des risques associes
WO2008048986A2 (fr) * 2006-10-17 2008-04-24 Children's Hospital Medical Center Technique par batterie de gènes pour prédire la réponse dans les maladies intestinales inflammatoires
WO2008104608A1 (fr) * 2007-03-01 2008-09-04 Universite Catholique De Louvain Procédé pour la détermination et la classification de conditions rhumatismales
WO2008157282A1 (fr) * 2007-06-18 2008-12-24 Genentech, Inc. Marqueurs biologiques prédictifs d'une réponse d'arthrite rhumatoïde à des antagonistes de cellule b
WO2010113096A1 (fr) * 2009-03-30 2010-10-07 Tel Hashomer Medical Research Infrastructure And Services Ltd. Méthodes pour prévoir l'évolution clinique de la sclérose en plaque et la traiter
US20110091457A1 (en) * 2009-10-16 2011-04-21 Cornelis Lammert Verweij Method for prognosticating the clinical response of a patient to b-lymphocyte inhibiting or depleting therapy
WO2011154139A2 (fr) * 2010-06-07 2011-12-15 Roche Diagnostics Gmbh Marqueurs d'expression génique pour la prédiction d'une réponse à un traitement par un médicament anticorps monoclonal inhibant le récepteur de l'interleukine-6

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Also Published As

Publication number Publication date
BR112014019274A2 (pt) 2017-06-27
AU2013217940A1 (en) 2014-07-31
EP2812445A2 (fr) 2014-12-17
CN104204230A (zh) 2014-12-10
KR20140124767A (ko) 2014-10-27
WO2013117751A2 (fr) 2013-08-15
MX2014009490A (es) 2014-08-29
CA2864133A1 (fr) 2013-08-15

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