WO2014016548A3 - Composition pharmaceutique - Google Patents

Composition pharmaceutique Download PDF

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Publication number
WO2014016548A3
WO2014016548A3 PCT/GB2013/000328 GB2013000328W WO2014016548A3 WO 2014016548 A3 WO2014016548 A3 WO 2014016548A3 GB 2013000328 W GB2013000328 W GB 2013000328W WO 2014016548 A3 WO2014016548 A3 WO 2014016548A3
Authority
WO
WIPO (PCT)
Prior art keywords
olodaterol
further active
pharmaceutical composition
relates
present
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/GB2013/000328
Other languages
English (en)
Other versions
WO2014016548A2 (fr
Inventor
Shrinivas Madhukar Purandare
Geena Malhotra
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cipla Ltd
Original Assignee
Cipla Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cipla Ltd filed Critical Cipla Ltd
Publication of WO2014016548A2 publication Critical patent/WO2014016548A2/fr
Publication of WO2014016548A3 publication Critical patent/WO2014016548A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/538—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La présente invention porte sur des compositions pharmaceutiques pour inhalation qui comprennent un ou plusieurs bronchodilatateurs et un corticostéroïde inhalé. Plus particulièrement, la présente invention porte sur des compositions pharmaceutiques comprenant de l'olodaterol, un corticostéroïde inhalé et/ou un agent anticholinergique. La présente invention porte également sur un procédé pour la préparation de la composition pharmaceutique et sur son utilisation dans le traitement et/ou la prévention d'une maladie respiratoire, inflammatoire ou obstructive des voies aériennes.
PCT/GB2013/000328 2012-07-27 2013-07-29 Composition pharmaceutique Ceased WO2014016548A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN2161MU2012 2012-07-27
IN2161/MUM/2012 2012-07-27

Publications (2)

Publication Number Publication Date
WO2014016548A2 WO2014016548A2 (fr) 2014-01-30
WO2014016548A3 true WO2014016548A3 (fr) 2014-03-20

Family

ID=48949176

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2013/000328 Ceased WO2014016548A2 (fr) 2012-07-27 2013-07-29 Composition pharmaceutique

Country Status (1)

Country Link
WO (1) WO2014016548A2 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX370430B (es) * 2014-06-18 2019-12-13 Boehringer Ingelheim Vetmedica Gmbh Antagonistas muscarínicos y sus combinaciones para el tratamiento de enfermedades de las vías respiratorias en caballos.
CN104546861A (zh) * 2015-01-13 2015-04-29 段希福 一种包含奥达特罗和环索奈德的药物组合物及其用途
GB2545025A (en) * 2015-12-04 2017-06-07 Mexichem Fluor Sa De Cv Pharmaceutical composition
EP3556348B1 (fr) 2015-12-04 2021-02-03 Mexichem Fluor S.A. de C.V. Composition pharmaceutique
ES2904823T3 (es) * 2016-09-19 2022-04-06 Mexichem Fluor Sa De Cv Composición farmacéutica que comprende bromuro de tiotropio
US20190290633A1 (en) * 2017-10-27 2019-09-26 Nephron Pharmaceuticals Corporation Tiotropium Inhalation Solution for Nebulization
WO2019142214A1 (fr) * 2018-01-19 2019-07-25 Cipla Limited Composition pharmaceutique comprenant du tiotropium destinée à être inhalée
CN110876722A (zh) * 2018-09-06 2020-03-13 天津金耀集团有限公司 一种含有表面活性剂的噻托溴铵奥达特罗喷雾剂
CN110876724A (zh) * 2018-09-06 2020-03-13 天津金耀集团有限公司 依地酸盐恰当改变噻托溴铵奥达特罗喷雾剂表面张力的应用
CN115209884B (zh) * 2020-01-20 2024-05-28 广州谷森制药有限公司 含有格隆溴铵和盐酸奥达特罗的可吸入制剂
US20210322311A1 (en) * 2020-04-16 2021-10-21 Cai Gu Huang Inhalable Formulation of a Solution Containing Tiotropium Bromide and Olodaterol
WO2021262648A1 (fr) * 2020-06-23 2021-12-30 Anovent Pharmaceutical (U.S.), Llc Préparation d'une composition pharmaceutique d'olodatérol et de budésonide
CN114028364A (zh) * 2021-11-26 2022-02-11 南京华盖制药有限公司 一种奥达特罗吸入溶液
CN117679423A (zh) * 2022-09-05 2024-03-12 立生医药(苏州)有限公司 预防或治疗呼吸系统疾病的吸入用药物组合物

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005102349A1 (fr) * 2004-04-22 2005-11-03 Boehringer Ingelheim International Gmbh Combinaisons medicamenteuses contenant de la benzoxazine pour traiter des maladies des voies respiratoires
WO2008020056A2 (fr) * 2006-08-18 2008-02-21 Boehringer Ingelheim International Gmbh Formulation aérosol pour l'inhalation de bêta-agonistes
WO2008020057A1 (fr) * 2006-08-18 2008-02-21 Boehringer Ingelheim International Gmbh Formulation d'aérosol pour l'inhalation de bêta-agonistes
WO2009059893A1 (fr) * 2007-11-05 2009-05-14 Boehringer Ingelheim International Gmbh Hydrate cristallin de bêta-mimétique et son utilisation en tant que médicament
WO2011073231A1 (fr) * 2009-12-18 2011-06-23 Nycomed Gmbh Dérivés de 3,4,4a,10b-tétrahydro-1h-thiopyrano-[4,3-c]isoquinoline
WO2012110770A2 (fr) * 2011-02-17 2012-08-23 Cipla Limited Composition pharmaceutique

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050239778A1 (en) 2004-04-22 2005-10-27 Boehringer Ingelheim International Gmbh Novel medicament combinations for the treatment of respiratory diseases
US20070088030A1 (en) 2005-10-10 2007-04-19 Barbara Niklaus-Humke Aerosol formulations for the inhalation of beta-agonists
TWI396541B (zh) 2005-10-10 2013-05-21 Boehringer Ingelheim Int 用於治療呼吸疾病之新穎藥物組合

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005102349A1 (fr) * 2004-04-22 2005-11-03 Boehringer Ingelheim International Gmbh Combinaisons medicamenteuses contenant de la benzoxazine pour traiter des maladies des voies respiratoires
WO2008020056A2 (fr) * 2006-08-18 2008-02-21 Boehringer Ingelheim International Gmbh Formulation aérosol pour l'inhalation de bêta-agonistes
WO2008020057A1 (fr) * 2006-08-18 2008-02-21 Boehringer Ingelheim International Gmbh Formulation d'aérosol pour l'inhalation de bêta-agonistes
WO2009059893A1 (fr) * 2007-11-05 2009-05-14 Boehringer Ingelheim International Gmbh Hydrate cristallin de bêta-mimétique et son utilisation en tant que médicament
WO2011073231A1 (fr) * 2009-12-18 2011-06-23 Nycomed Gmbh Dérivés de 3,4,4a,10b-tétrahydro-1h-thiopyrano-[4,3-c]isoquinoline
WO2012110770A2 (fr) * 2011-02-17 2012-08-23 Cipla Limited Composition pharmaceutique

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
M. CAZZOLA ET AL: "Pharmacology and Therapeutics of Bronchodilators", PHARMACOLOGICAL REVIEWS, vol. 64, no. 3, 18 May 2012 (2012-05-18), pages 450 - 504, XP055083801, DOI: 10.1124/pr.111.004580 *

Also Published As

Publication number Publication date
WO2014016548A2 (fr) 2014-01-30

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