WO2014074382A2 - Injecteur de lentille intraoculaire pré-chargé - Google Patents

Injecteur de lentille intraoculaire pré-chargé Download PDF

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Publication number
WO2014074382A2
WO2014074382A2 PCT/US2013/067694 US2013067694W WO2014074382A2 WO 2014074382 A2 WO2014074382 A2 WO 2014074382A2 US 2013067694 W US2013067694 W US 2013067694W WO 2014074382 A2 WO2014074382 A2 WO 2014074382A2
Authority
WO
WIPO (PCT)
Prior art keywords
cartridge
iol
injector
seal
proximal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2013/067694
Other languages
English (en)
Other versions
WO2014074382A3 (fr
Inventor
Yakir KUSHLIN
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hanita Lenses RCA Ltd
Original Assignee
Hanita Lenses RCA Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hanita Lenses RCA Ltd filed Critical Hanita Lenses RCA Ltd
Publication of WO2014074382A2 publication Critical patent/WO2014074382A2/fr
Publication of WO2014074382A3 publication Critical patent/WO2014074382A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2/1662—Instruments for inserting intraocular lenses into the eye
    • A61F2/1678—Instruments for inserting intraocular lenses into the eye with a separate cartridge or other lens setting part for storage of a lens, e.g. preloadable for shipping

Definitions

  • the present invention relates generally to devices and methods for inserting an intraocular lens (IOL) into an eye, and particularly wherein the IOL is preloaded in the injector device.
  • IOL intraocular lens
  • An IOL injector is a well-known device that inserts an IOL into the eye of a patient during surgical replacement of the natural lens of the eye. Prior to implantation, the IOL must first be loaded into the IOL inserter device. Some IOL injectors require the IOL to be loaded into the injector at the time of surgery by the surgeon or other personnel. However, due to the delicate nature of the IOL, there is a risk of inadvertent damage to the IOL and/or incorrect loading of the IOL into the injector, which can result in a failed implantation and in some cases an adverse event may occur. Moreover, direct handling and/or loading of the IOL into the injector is undesirable in terms of ease of use, ergonomics, sterility and logistics.
  • Preloaded injector devices have been developed, in which the injector device and IOL are packaged together as a single unit or loaded on a cartridge that is easily loaded into the injector.
  • the IOL is held in a preloaded position in an unstressed state (substantially no stress acts upon the optic or haptic portion of the lens).
  • the IOL may be flushed with saline solution.
  • a viscoelastic liquid may be introduced into the distal end of the injector in order to lubricate movement of the IOL into the barrel of the injector nozzle.
  • the plunger of the injector is then pushed forward, which pushes the lens to the end of the injector tip for subsequent insertion, typically through an incision in the anterior capsule into the bag.
  • the present invention seeks to provide a novel preloaded IOL injector, as is described more in detail hereinbelow.
  • an IOL preloaded in a cartridge the cartridge being pre- sealed at proximal and distal ends thereof by at least one seal, the cartridge being placed on a receiving member of an injector, the injector including a plunger which is arranged to be pushed distally so as to push the IOL distally.
  • the plunger can puncture a proximal seal end of the at least one seal, and can be pushed further distally to puncture a distal seal end of the at least one seal and to move the IOL to a tip of the injector.
  • one or both of the seals is manually opened and the plunger pushes the lens to the tip of the injector.
  • the seal can be a single seal that seals both the proximal and the distal ends of the cartridge.
  • the seal can include a proximal sealing element that seals the proximal end of the cartridge and a separate distal sealing element that seals the distal end of the cartridge.
  • the cartridge is mounted on a raisable base, and a raising member is mechanically linked to the base for moving the IOL into alignment with the plunger.
  • Figs. 1A and IB are simplified perspective illustrations, respectively, of a cartridge for holding therein an IOL and the cartridge preloaded in a preloaded IOL injector, constructed and operative in accordance with an embodiment of the present invention, wherein the cartridge includes a sealing element that seals both proximal and distal ends of the cartridge;
  • FIGs. 2A and 2B are simplified perspective illustrations, respectively, of a cartridge for holding therein an IOL and the cartridge preloaded in a preloaded IOL injector, constructed and operative in accordance with another embodiment of the present invention, wherein the cartridge includes separate sealing elements for sealing the proximal and distal ends of the cartridge; and
  • FIGs. 3 A and 3B are simplified perspective and close-up illustrations, respectively, of a preloaded IOL injector, constructed and operative in accordance with yet another embodiment of the present invention, wherein the IOL is preloaded in a cartridge on a raisable base.
  • FIG. 1A and IB illustrate a preloaded IOL injector 10, constructed and operative in accordance with an embodiment of the present invention.
  • An IOL 12 is preloaded in a cartridge 14 (also called a cassette).
  • Cartridge 14 is pre-sealed at both ends by one integral seal 16 (shown only partially in Fig. 1A).
  • Seal 16 may be made of a medically safe elastomeric material, such as synthetic rubber. Depending on the application, seal 16 can permit or not permit gas flux.
  • Cartridge 14 is placed on a receiving member 18 of injector 10.
  • Cartridge 14 may be secured there by using either mechanical, chemical, magnetic forces or other mediators.
  • Cartridge 14 is pre- sterilized before mounting in injector 10. Afterwards, cartridge 14 is mounted on injector 10 and final sterilization is done. Thus, the lens cassette/cartridge 14 is supplied mounted on the injector 10 after final sterilization for use in the surgery room.
  • a plunger 20 of injector 10 can be pushed forwards (distally) to puncture the first (proximal) seal end of seal 16, which pushes IOL 12 distally. Continued pushing of plunger 20 punctures the second (distal) seal end of seal 16 and moves IOL 12 to a tip 22 of injector 10, from which IOL 12 can be expelled and injected into the eye (not shown).
  • plunger 20 can be manually opened, and plunger 20 pushes IOL 12 to the tip of injector 10.
  • Figs. 2A and 2B This embodiment is similar to the embodiment of Figs. 1A and IB, except that in this embodiment, cartridge 14 includes separate sealing elements 16a and 16B for sealing the proximal and distal ends of cartridge 14, respectively.
  • FIGs. 3A and 3B illustrate a preloaded IOL injector 30, constructed and operative in accordance with yet another embodiment of the present invention.
  • IOL 12 is preloaded in a cassette 32 on a raisable base 34.
  • a raising member 36 (such as a knob) mechanically linked to base 34. By turning knob 36, base 34 rises and brings IOL 12 into alignment with the plunger 20 for injection into the eye.
  • cassette 32, base 34 and raising member 36 are mounted with the injector 30 and undergo final sterilization before supplying to the user.
  • a method for mounting preloded IOL 12 in injector 10 wherein IOL 12 is placed in cartridge 14 which has an environment free of atmospheric gases (such as an anaerobic environment, or an environment filled with a fluid such as water, oil, viscous polymer, non-atmospheric gas or other suitable liquid or gas).
  • an environment free of atmospheric gases such as an anaerobic environment, or an environment filled with a fluid such as water, oil, viscous polymer, non-atmospheric gas or other suitable liquid or gas.
  • the assembly of IOL 12 and cartridge 14 can be sterilized with a different sterilization method than that used to sterilize the injector and /or the injector tip.

Landscapes

  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Prostheses (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

L'invention porte sur une lentille intraoculaire, qui est pré-chargée dans une cartouche, l'ensemble lentille intraoculaire/cartouche étant pré-stérilisé. Ensuite, l'ensemble lentille intraoculaire/cartouche est monté dans un injecteur de lentille intraoculaire. Une stérilisation finale est effectuée sur la cartouche montée dans l'injecteur.
PCT/US2013/067694 2012-11-07 2013-10-31 Injecteur de lentille intraoculaire pré-chargé Ceased WO2014074382A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261723358P 2012-11-07 2012-11-07
US61/723,358 2012-11-07

Publications (2)

Publication Number Publication Date
WO2014074382A2 true WO2014074382A2 (fr) 2014-05-15
WO2014074382A3 WO2014074382A3 (fr) 2014-08-21

Family

ID=49817245

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2013/067694 Ceased WO2014074382A2 (fr) 2012-11-07 2013-10-31 Injecteur de lentille intraoculaire pré-chargé

Country Status (1)

Country Link
WO (1) WO2014074382A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10722346B2 (en) 2017-09-19 2020-07-28 Bausch & Lomb Incorporated Intraocular lens injector assembly having shuttle assembly retaining intraocular lens in storage vial and operably presenting intraocular lens in injector assembly

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6605093B1 (en) * 1997-10-24 2003-08-12 Tekia, Inc. Device and method for use with an ophthalmologic insertor apparatus
EP1845899B1 (fr) * 2004-12-29 2011-06-29 Bausch & Lomb Incorporated Méthode de préparation d'injecteur préchargé de lentille intraoculaire
US7879090B2 (en) * 2006-12-13 2011-02-01 Bausch & Lomb Incorporated Intraocular lens injector apparatus and methods of use
CH699588A1 (de) * 2008-09-22 2010-03-31 Medicel Ag Kassette für eine intraokulare Linse und Injektorsystem dafür.

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
None

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10722346B2 (en) 2017-09-19 2020-07-28 Bausch & Lomb Incorporated Intraocular lens injector assembly having shuttle assembly retaining intraocular lens in storage vial and operably presenting intraocular lens in injector assembly
US12127935B2 (en) 2017-09-19 2024-10-29 Bausch & Lomb Incorporated Intraocular lens injector assembly having shuttle assembly retaining intraocular lens in storage vial and operably presenting intraocular lens in injector assembly

Also Published As

Publication number Publication date
WO2014074382A3 (fr) 2014-08-21

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