WO2014100358A2 - Compositions nutritionnelles ayant des avantages sur la santé cardiaque - Google Patents

Compositions nutritionnelles ayant des avantages sur la santé cardiaque Download PDF

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Publication number
WO2014100358A2
WO2014100358A2 PCT/US2013/076428 US2013076428W WO2014100358A2 WO 2014100358 A2 WO2014100358 A2 WO 2014100358A2 US 2013076428 W US2013076428 W US 2013076428W WO 2014100358 A2 WO2014100358 A2 WO 2014100358A2
Authority
WO
WIPO (PCT)
Prior art keywords
composition
grams
protein
liquid nutritional
nutritional composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2013/076428
Other languages
English (en)
Other versions
WO2014100358A3 (fr
Inventor
Gaurav PATEL
Normanella Dewille
Paul Johns
Kelley LOWE
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of WO2014100358A2 publication Critical patent/WO2014100358A2/fr
Publication of WO2014100358A3 publication Critical patent/WO2014100358A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
    • A23L2/52—Adding ingredients
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
    • A23L2/52—Adding ingredients
    • A23L2/66—Proteins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/20—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents
    • A23L29/269—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of microbial origin, e.g. xanthan or dextran
    • A23L29/271—Curdlan; beta-1-3 glucan; Polysaccharides produced by agrobacterium or alcaligenes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/185—Vegetable proteins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/20—Reducing nutritive value; Dietetic products with reduced nutritive value
    • A23L33/21—Addition of substantially indigestible substances, e.g. dietary fibres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

Definitions

  • This embodiment also includes the use of a liquid nutritional composition in the manufacture of a medicament for use in improving the cardiovascular health of an individual in need thereof wherein the liquid nutritional composition comprises at most 1 gram total fat per 100 grams of the nutritional composition; at least one source of protein in an amount sufficient to provide 6.25-20 grams of protein per serving; at least one source of carbohydrates; vitamins and minerals; and at least one source of viscous soluble fiber providing between 0.75 and 3 grams of beta-glucan per serving.
  • a clear, shelf-stable liquid nutritional composition with heart health benefits is provided.
  • the clear, shelf-stable liquid nutritional composition according to the second embodiment includes at least one source of protein in an amount sufficient to provide 9-15 grams protein per serving, at least one source of carbohydrates; 0.75-3 grams beta- glucan fiber per serving, and at most 1 gram of fat per 100 grams ⁇ i.e., no more than 1 weight % fat based on total weight of the liquid nutritional composition).
  • the composition is a composition for improving the heart health of an individual.
  • Typical serving sizes range about 100-500 mL, including about 100-300 mL, including about 150-250 mL, including about 190-240 mL and also including 4-10 fluid ounces, 8-10 fluid ounces and 8 fluid ounces and 10 fluid ounces).
  • Various calorie contents may be associated with each serving of the nutritional compositions according to the first, second and third embodiments disclosed herein, typically 25-500 Kcal, including 50-250 Kcal; 100-200 Kcal or 150-180 Kcal per serving.
  • a serving may be construed as any amount which is intended to be consumed in one sitting or within one hour or less.
  • the liquid nutritional compositions include beta-glucan.
  • the liquid nutritional compositions comprise viscous or viscous soluble fiber. Viscous fibers are characterized by their ability to form a liquid or gel solution when combined with water in the digestive tract. Viscous fibers are known to bind with fatty acids in the stomach to create a viscous mass. Examples of sub-sets of viscous fibers include pectins, such as those found in apples; beta-glucans; guar gum; and mucilages, such as psyllium husk. Beta-glucan is a natural source of soluble fiber.
  • Beta-glucan molecules consist of linked chains of D-glucose polysaccharides. Though similar, beta-glucans are more diverse than molecules like starch. Some beta-glucans exist as single strand chains while others have complex helical arrangements. The particular arrangement is often due to the source of beta-glucan, with some arrangements, known as ⁇ ( 1,3)0,4), showing interesting biological activity. Some known sources of beta-glucan are cereals such as barley, oat, triticale, wheat, rice, corn, amaranth and quinoa among others. Generally, beta- glucans extracted from grains are both soluble and insoluble, while beta-glucan derived from baker's yeast is mainly insoluble.
  • the liquid nutritional compositions according to the first, second and third embodiments disclosed herein contain at least one source of carbohydrates, in certain embodiments more than one source.
  • the particular amount of carbohydrates present in the liquid nutritional composition may vary depending upon the nutritional needs of the intended user.
  • the total amount of carbohydrates present in liquid nutritional compositions according to the first, second and third embodiments disclosed herein will usually fall within the range of 5-40 weight % (percentages are weight percentages based upon the total weight of the liquid nutritional composition), 7-30 weight %, or 10-20 weight %.
  • the amount of carbohydrates present in liquid nutritional compositions according to the first, second and third embodiments disclosed herein can also be characterized as a percentage of total calories in the liquid nutritional composition and may vary widely.
  • the at least one source of carbohydrate comprises 10-85% of the total calories of the liquid nutritional composition and in other embodiments 20-60% of the total calories.
  • the liquid nutritional composition includes at least one source of carbohydrates in an amount sufficient to provide a total of 100-200 grams of carbohydrate per liter of liquid nutritional composition.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Nutrition Science (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Mycology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

L'invention concerne des compositions nutritionnelles et des procédés utiles pour l'amélioration de la santé cardiaque d'un individu. Les compositions nutritionnelles liquides comprennent une protéine, des glucides et bêta-glucane. Dans certains modes de réalisation, les compositions nutritionnelles liquides remplissent un ou plusieurs des éléments suivants : contiennent au moins 6,25 grammes de protéine de soja, contiennent au moins 0,75 gramme de bêta-glucane, sont claires ou ont un pH de 2-4,6.
PCT/US2013/076428 2012-12-19 2013-12-19 Compositions nutritionnelles ayant des avantages sur la santé cardiaque Ceased WO2014100358A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261739273P 2012-12-19 2012-12-19
US61/739,273 2012-12-19

Publications (2)

Publication Number Publication Date
WO2014100358A2 true WO2014100358A2 (fr) 2014-06-26
WO2014100358A3 WO2014100358A3 (fr) 2014-09-12

Family

ID=49917774

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2013/076428 Ceased WO2014100358A2 (fr) 2012-12-19 2013-12-19 Compositions nutritionnelles ayant des avantages sur la santé cardiaque

Country Status (2)

Country Link
TW (1) TW201438600A (fr)
WO (1) WO2014100358A2 (fr)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040087514A1 (en) * 2002-09-06 2004-05-06 Hughes Thomas E Nutritional compositions
EP2346361B1 (fr) * 2008-08-29 2013-09-18 Tropicana Products, Inc. Boissons a base de jus de fruits naturellement edulcorees contenant du beta-glucane
WO2012024270A1 (fr) * 2010-08-17 2012-02-23 Abbott Laboratories Composition nutritionnelle comprenant du bêta-glucane de céréale et un extrait de salacia
EP2700321A1 (fr) * 2012-08-24 2014-02-26 Etablissements J. Soufflet Composition alimentaire aqueuse enrichie en bêta-glucane

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
BRYAN A. GARNER: "A Dictionary of Modern Legal Usage", 1995, pages: 624

Also Published As

Publication number Publication date
TW201438600A (zh) 2014-10-16
WO2014100358A3 (fr) 2014-09-12

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