WO2014100880A3 - Molécules variantes synthétiques de toxines cry1ia12 à propriétés de lutte contre les insectes nuisibles, compositions contenant ces mutants et procédé d'utilisation correspondants - Google Patents

Molécules variantes synthétiques de toxines cry1ia12 à propriétés de lutte contre les insectes nuisibles, compositions contenant ces mutants et procédé d'utilisation correspondants Download PDF

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Publication number
WO2014100880A3
WO2014100880A3 PCT/BR2013/000609 BR2013000609W WO2014100880A3 WO 2014100880 A3 WO2014100880 A3 WO 2014100880A3 BR 2013000609 W BR2013000609 W BR 2013000609W WO 2014100880 A3 WO2014100880 A3 WO 2014100880A3
Authority
WO
WIPO (PCT)
Prior art keywords
molecules
cry1ia12
insect pests
controlling insect
mutants
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/BR2013/000609
Other languages
English (en)
Portuguese (pt)
Other versions
WO2014100880A2 (fr
Inventor
Maria Fátima GROSSI DE SÁ
Maria Cristina Mattar Da Silva
José Edilson GOMES JÚNIOR
Isabela TRISTAN LOURENÇO
Leonardo LIMA PEPINO DE MACEDO
Wagner Alexandre LUCENA
Fernando CAMPOS DE ASSIS FONSECA
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Brazilian Agricultural Research Corporation
Fundacao Universidade de Brasilia
Original Assignee
Brazilian Agricultural Research Corporation
Fundacao Universidade de Brasilia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Brazilian Agricultural Research Corporation, Fundacao Universidade de Brasilia filed Critical Brazilian Agricultural Research Corporation
Publication of WO2014100880A2 publication Critical patent/WO2014100880A2/fr
Publication of WO2014100880A3 publication Critical patent/WO2014100880A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
    • C07K14/325—Bacillus thuringiensis crystal peptides, i.e. delta-endotoxins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Catching Or Destruction (AREA)

Abstract

La présente invention concerne le domaine de la lutte contre les insectes nuisibles par utilisation de procédés et de compositions comprenant des analogues mutants de δ-endotoxines. Plus particulièrement, la présente invention vise à obtenir de nouvelles molécules à partir du gène Cry1la12 avec une toxicité améliorée, en vue de rendre les plantes de canne à sucre résistantes au foreur géant de la canne à sucre, produisant des plantes transgéniques capables d'exprimer des toxines à haute activité entomotoxique; à obtenir des δ-endotoxines améliorées au moyen de procédés biotechnologiques; à contribuer à la réduction des doses d'application d'agents chimiques protecteurs avec réduction des coûts sociaux et environnementaux et augmentation de la productivité de la culture. L'invention concerne également des constructions géniques contenant les molécules d'acide nucléique codant pour Cry1la12 modifié, des procédés pour l'expression hétérologue des nouvelles molécules dans la forme active, ainsi que l'utilisation de celles-ci dans la lutte contre les insectes nuisibles. L'invention concerne en outre des gènes analogues synthétiques, lesquels sont optimisés en vue de leur transformation et de leur expression dans des plantes.
PCT/BR2013/000609 2012-12-28 2013-12-27 Molécules variantes synthétiques de toxines cry1ia12 à propriétés de lutte contre les insectes nuisibles, compositions contenant ces mutants et procédé d'utilisation correspondants Ceased WO2014100880A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
BR102012033542-5A BR102012033542B1 (pt) 2012-12-28 2012-12-28 Moléculas variantes sintéticas de toxinas cry1ia12 com propriedades de controlar insetos-praga, composições contendo tais mutantes e método de utilização dos mesmos
BRBR1020120335425 2012-12-28

Publications (2)

Publication Number Publication Date
WO2014100880A2 WO2014100880A2 (fr) 2014-07-03
WO2014100880A3 true WO2014100880A3 (fr) 2014-11-06

Family

ID=51022143

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/BR2013/000609 Ceased WO2014100880A2 (fr) 2012-12-28 2013-12-27 Molécules variantes synthétiques de toxines cry1ia12 à propriétés de lutte contre les insectes nuisibles, compositions contenant ces mutants et procédé d'utilisation correspondants

Country Status (3)

Country Link
AR (1) AR094338A1 (fr)
BR (1) BR102012033542B1 (fr)
WO (1) WO2014100880A2 (fr)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6063605A (en) * 1989-05-09 2000-05-16 Zeneca Limited Bacillus thuringiensis endotoxin genes and methods of use
WO2004074462A2 (fr) * 2003-02-20 2004-09-02 Athenix Corporation Genes de delta-endotoxines et leurs methodes d'utilisation
US20050049410A1 (en) * 2003-08-28 2005-03-03 Athenix Corporation AXMI-003, a delta-endotoxin gene and methods for its use

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6063605A (en) * 1989-05-09 2000-05-16 Zeneca Limited Bacillus thuringiensis endotoxin genes and methods of use
WO2004074462A2 (fr) * 2003-02-20 2004-09-02 Athenix Corporation Genes de delta-endotoxines et leurs methodes d'utilisation
US20050049410A1 (en) * 2003-08-28 2005-03-03 Athenix Corporation AXMI-003, a delta-endotoxin gene and methods for its use

Also Published As

Publication number Publication date
BR102012033542A2 (pt) 2014-08-19
BR102012033542B1 (pt) 2021-08-24
AR094338A1 (es) 2015-07-29
WO2014100880A2 (fr) 2014-07-03

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