WO2014109726A2 - Implant utilisé dans le traitement d'un os cassé et son procédé de production - Google Patents

Implant utilisé dans le traitement d'un os cassé et son procédé de production Download PDF

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Publication number
WO2014109726A2
WO2014109726A2 PCT/TR2014/000006 TR2014000006W WO2014109726A2 WO 2014109726 A2 WO2014109726 A2 WO 2014109726A2 TR 2014000006 W TR2014000006 W TR 2014000006W WO 2014109726 A2 WO2014109726 A2 WO 2014109726A2
Authority
WO
WIPO (PCT)
Prior art keywords
treatment
production method
alloy
implant
broken bone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/TR2014/000006
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English (en)
Other versions
WO2014109726A3 (fr
Inventor
Benat KOCKAR
Vahid ATTARI
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of WO2014109726A2 publication Critical patent/WO2014109726A2/fr
Publication of WO2014109726A3 publication Critical patent/WO2014109726A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/04—Metals or alloys
    • A61L27/06—Titanium or titanium alloys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/02—Inorganic materials
    • A61L31/022—Metals or alloys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Definitions

  • the present invention relates to an implant used for broken bone treatment by providing union of the bones, through having elastic modulus close to the elastic modulus of human bone, and a production method thereof.
  • the treatment of bone fractures is based on the re-integration of bones to each other. For this reason, different materials and different implants produced from these materials are developed. Since the mechanical properties, especially the elastic modulus of the previously used pure titanium, titanium-aluminum- vanadium and the other titanium based alloys are very much higher than the elastic modulus of human bone, under a probable load, these implants cannot share the load with the bone, therefore cause difficulty in the treatment of the bone fracture. At the present time, especially the miniplates used in the mandible (lower jaw bone) fractures cannot protect the bone under the bite force and cause the patient not to be recovered.
  • Chinese utility model no CN2668063 an application known in the state of the art, discloses a material, which is placed to the mandible to enable the defective bones to be brought closer and thus fulfils the treatment of these bones.
  • the said material is comprised of a reparative titanium plate, a miniature canal shaped titanium miniplate and a titanium-nickel alloy spring.
  • each tip of the titanium plate is attached to bones which are staying apart.
  • the miniature titanium plate anchors the titanium plate by crossing over the other plate.
  • the titanium-nickel alloy spring provides the flexibility between the two bones.
  • Chinese patent No. CN101066227 another application known in the state of the art, discloses mandible hammer made of a NiTi alloy material.
  • the said material includes a U-type guiding rod, two sliding parts having holes which provide sliding on the guiding rod and a extension spring with the omega shape.
  • the elastic mechanical properties of the said NiTi alloy material are improved via a specific heat treatment and are made it suitable for human bone expansion.
  • the said invention does not constitute any barrier to the elongation of the bone properly and through the correct direction.
  • German patent document no. DE102005032026 an application known in the state of the art, discloses a plate which is used for the treatment of mandible fractures.
  • the said plate may hold very different shapes and be fixed to the bone using pins via the holes on it.
  • this plate is produced from titanium material.
  • the objective of the present invention is to provide an implant made from a material having elastic modulus close to the elastic modulus of human bone used in the treatment of broken bone.
  • Another objective of the present invention is to provide an implant and production method thereof in the treatment of broken bone using titanium-niobium (TiNb) alloy material.
  • Yet another objective of the present invention is to provide an implant used in the treatment of broken mandible (lower j aw) .
  • An implant production method used in the treatment of the broken bone (100) developed to fulfill the objectives of the present invention comprises the steps of
  • the mixture is exposed to heat treatment for at least 1 hour at 800-1000°C temperature, under vacuum and/or protective atmosphere (104).
  • the said alloy undergoes to deformation processes such as rolling, extrusion, pressing or precipitation hardening process to provide an increase in its strength.
  • Precipitation hardening (105) is a heat treatment, which is applied to the alloy at 500-600°C for approximately 1 hour.
  • the material which is strengthened by the cold deformation or precipitation hardening processes (105) is lastly processed to its final shape by the computer aided or manual metal processing techniques and the implant is produced (106).
  • the implants produced with the inventive method (100) can be used in the treatment of bones in the different parts of the body.
  • TiNb alloy material is processed into a miniplate shape at the step of giving the final shape (106).
  • This miniplate which is to be used at the fractured mandible (lower jaw) provides the osteointegration of the bones by being placed between broken bones.
  • the finite element method analysis results of the TiNb material and pure titanium are shown in the Table 1 below. As it can be seen from the Von Mises stress values of the TiNb alloy miniplates having lower elastic modulus, there is a sharing of anterior and posterior loadings between the bone and miniplate. Thus, the miniplate is not going to be damaged, the fracture or fractures will be healed rapidly and the sufficiency of placing only one miniplate provides easiness to the dentist doing the operation. Table 1.

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Prostheses (AREA)

Abstract

La présente invention concerne un implant utilisé pour le traitement de l'os cassé et son procédé de production pour permettre l'ostéointégration des os en ayant la valeur de module d'élasticité proche du module d'élasticité d'un os humain, et comprend les étapes consistant à mélanger les métaux par l'intermédiaire d'une fusion (101), à verser le mélange dans le moule (102), à retirer le mélange du moule par l'intermédiaire d'un refroidissement (103), à appliquer un traitement thermique à l'alliage (104), à traiter l'alliage produit par déformation à froid ou durcissement par précipitation (105) et à donner la forme finale à l'implant (106).
PCT/TR2014/000006 2013-01-10 2014-01-10 Implant utilisé dans le traitement d'un os cassé et son procédé de production Ceased WO2014109726A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
TR2013/00366 2013-01-10
TR201300366 2013-01-10

Publications (2)

Publication Number Publication Date
WO2014109726A2 true WO2014109726A2 (fr) 2014-07-17
WO2014109726A3 WO2014109726A3 (fr) 2014-09-04

Family

ID=50514032

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/TR2014/000006 Ceased WO2014109726A2 (fr) 2013-01-10 2014-01-10 Implant utilisé dans le traitement d'un os cassé et son procédé de production

Country Status (1)

Country Link
WO (1) WO2014109726A2 (fr)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2668063Y (zh) 2003-08-04 2005-01-05 胡敏 多用途内置式下颌骨自动牵引成骨装置
DE102005032026B3 (de) 2005-07-08 2006-12-14 Stryker Leibinger Gmbh & Co. Kg Osteosyntheseplatte mit schräg zur Plattenebene verlaufenden Durchgangsöffnungen
CN101066227A (zh) 2007-06-01 2007-11-07 哈尔滨工程大学 镍钛下颌骨牵引器及制作方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5477864A (en) * 1989-12-21 1995-12-26 Smith & Nephew Richards, Inc. Cardiovascular guidewire of enhanced biocompatibility
DE102006025292A1 (de) * 2006-05-31 2007-12-06 Gfe Metalle Und Materialien Gmbh Biokompatible Titanlegierung, Verfahren zu deren Herstellung sowie daraus bestehendes medizinisches Knochen-Implantat

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2668063Y (zh) 2003-08-04 2005-01-05 胡敏 多用途内置式下颌骨自动牵引成骨装置
DE102005032026B3 (de) 2005-07-08 2006-12-14 Stryker Leibinger Gmbh & Co. Kg Osteosyntheseplatte mit schräg zur Plattenebene verlaufenden Durchgangsöffnungen
CN101066227A (zh) 2007-06-01 2007-11-07 哈尔滨工程大学 镍钛下颌骨牵引器及制作方法

Also Published As

Publication number Publication date
WO2014109726A3 (fr) 2014-09-04

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