WO2014140938A3 - Méthodes immunologiques - Google Patents
Méthodes immunologiques Download PDFInfo
- Publication number
- WO2014140938A3 WO2014140938A3 PCT/IB2014/001268 IB2014001268W WO2014140938A3 WO 2014140938 A3 WO2014140938 A3 WO 2014140938A3 IB 2014001268 W IB2014001268 W IB 2014001268W WO 2014140938 A3 WO2014140938 A3 WO 2014140938A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- immunological methods
- methods
- reagent
- disclosure relates
- immunological tolerance
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Mycology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Abstract
La présente invention concerne un réactif et des méthodes permettant de rompre la tolérance immunologique périphérique.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361781077P | 2013-03-14 | 2013-03-14 | |
| US61/781,077 | 2013-03-14 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO2014140938A2 WO2014140938A2 (fr) | 2014-09-18 |
| WO2014140938A3 true WO2014140938A3 (fr) | 2015-06-25 |
Family
ID=51355566
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/IB2014/001268 Ceased WO2014140938A2 (fr) | 2013-03-14 | 2014-03-14 | Méthodes immunologiques |
Country Status (1)
| Country | Link |
|---|---|
| WO (1) | WO2014140938A2 (fr) |
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| US5833975A (en) | 1989-03-08 | 1998-11-10 | Virogenetics Corporation | Canarypox virus expressing cytokine and/or tumor-associated antigen DNA sequence |
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| US5091309A (en) | 1986-01-16 | 1992-02-25 | Washington University | Sindbis virus vectors |
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| CA2076753A1 (fr) | 1990-02-26 | 1991-08-27 | Anthony J. Radford | Plasmide navette de escherichia coli et de mycobacteries |
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| WO1992015672A1 (fr) | 1991-03-07 | 1992-09-17 | Virogenetics Corporation | Souche de vaccin mise au point par genie genetique |
| CA2102623C (fr) | 1991-05-06 | 2003-04-22 | Jeffrey Schlom | Virus recombinant exprimant un antigene carcino-embryonnaire et methodes d'utilisation |
| US6235525B1 (en) | 1991-05-23 | 2001-05-22 | Ludwig Institute For Cancer Research | Isolated nucleic acid molecules coding for tumor rejection antigen precursor MAGE-3 and uses thereof |
| EP0587775A4 (fr) | 1991-06-06 | 1994-11-02 | Medimmune Inc | Induction de reponses de lymphocytes t cytotoxiques a des antigenes etrangers exprimes dans des mycobacteries. |
| AU6172194A (en) | 1993-02-08 | 1994-08-29 | Paravax, Inc. | Defective sindbis virus vectors that express (toxoplasma gondii) p30 antigens |
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| US5830753A (en) | 1994-09-30 | 1998-11-03 | Ludwig Institute For Cancer Research | Isolated nucleic acid molecules coding for tumor rejection antigen precursor dage and uses thereof. |
| WO1996010419A2 (fr) | 1994-10-03 | 1996-04-11 | The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services, Office Of Technology Transfer | Composition comprenant un virus de recombinaison exprimant un antigene et un virus de recombinaison exprimant une molecule immunostimulatrice |
| US6045802A (en) | 1994-10-03 | 2000-04-04 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Enhanced immune response to an antigen by a composition of a recombinant virus expressing the antigen with a recombinant virus expressing an immunostimulatory molecule |
| US5939526A (en) | 1995-03-21 | 1999-08-17 | Ludwig Institute For Cancer Research | Isolated RAGE-1 derived peptides which complex with HLA-B7 molecules and uses thereof |
| US5792462A (en) | 1995-05-23 | 1998-08-11 | University Of North Carolina At Chapel Hill | Alphavirus RNA replicon systems |
| US5990091A (en) | 1997-03-12 | 1999-11-23 | Virogenetics Corporation | Vectors having enhanced expression, and methods of making and uses thereof |
| ES2281935T3 (es) | 1997-10-08 | 2007-10-01 | The Government Of The Usa, As Represented By The Secretary, Department Of Health And Human Services | Antigeno cancerigeno humano ny eso-1/ca6 y gen que codifica para el mismo. |
| BR9913311A (pt) | 1998-08-31 | 2001-10-16 | Trinity College Dublin | Molécula de ácido nucleico isolado, ácido nucleico isolado, vetor, proteìna, anticorpo e anti-soros formados contra uma proteìna, kit de diagnóstico, processos para reduzir a infecção de estafilococos coagulase-negativos de um dispositivo médico de retenção, para tratar uma infecção de estafilococus coagulase-negativa, para prevenir uma infecção de estafilococos coagulase-negativa em um paciente, para induzir uma resposta imunológica e para identificar compostos que inibem estafilococos coagulase-negativos |
| US6329201B1 (en) | 1998-12-31 | 2001-12-11 | Chiron Corporation | Compositions and methods for packaging of alphavirus vectors |
| WO2000039318A1 (fr) | 1998-12-31 | 2000-07-06 | Chiron Corporation | Compositions et methodes permettant l'encapsidation de vecteurs d'alphavirus |
| JP5640237B2 (ja) | 1999-11-30 | 2014-12-17 | ルードヴィッヒ インスティテュート フォー キャンサー リサーチ リミテッド | 癌関連抗原をコードする単離された核酸分子、その抗原そのものおよびその使用 |
| DE60336653D1 (de) | 2002-08-07 | 2011-05-19 | Bavarian Nordic As | Vaccinia virus wirtspektrum gene zur erhöhung des titers von avipoxviren |
| US7473531B1 (en) | 2003-08-08 | 2009-01-06 | Colora Corporation | Pancreatic cancer targets and uses thereof |
-
2014
- 2014-03-14 WO PCT/IB2014/001268 patent/WO2014140938A2/fr not_active Ceased
Non-Patent Citations (7)
| Title |
|---|
| ANGELOS D GRITZAPIS ET AL: "Ontak reduces the immunosuppressive tumor environment and enhances successful therapeutic vaccination in HER-2/-tolerant mice", CANCER IMMUNOLOGY, IMMUNOTHERAPY, SPRINGER, BERLIN, DE, vol. 61, no. 3, 18 September 2011 (2011-09-18), pages 397 - 407, XP035018860, ISSN: 1432-0851, DOI: 10.1007/S00262-011-1113-4 * |
| BERNARD JC MACATANGAY ET AL: "Regulatory T cells in HIV immunotherapy", HIV THERAPY, vol. 4, no. 6, 1 November 2010 (2010-11-01), pages 639 - 647, XP055145123, ISSN: 1758-4310, DOI: 10.2217/hiv.10.51 * |
| CAROLA G VINUESA ET AL: "Follicular B helper T cells in antibody responses and autoimmunity", THE JOURNAL OF IMMUNOLOGY, NATURE PUB. GROUP, GB, vol. 5, no. 11, 1 November 2005 (2005-11-01), pages 853 - 865, XP008145950, ISSN: 1474-1733, DOI: 10.1038/NRI1714 * |
| CHIE KUDO-SAITO ET AL: "The Requirement of Multimodal Therapy (Vaccine, Local Tumor Radiation, and Reduction of Suppressor Cells) to Eliminate Established Tumors", CLINICAL CANCER RESEARCH, 15 June 2005 (2005-06-15), pages 4533 - 4544, XP055144888, Retrieved from the Internet <URL:http://clincancerres.aacrjournals.org/content/11/12/4533.full.pdf> [retrieved on 20141007], DOI: 10.1158/1078-0432.CCR-04-2237 * |
| GOMEZ ET AL: "Generation and immunogenicity of novel HIV/AIDS vaccine candidates targeting HIV-1 Env/Gag-Pol-Nef antigens of clade C", VACCINE, ELSEVIER LTD, GB, vol. 25, no. 11, 13 February 2007 (2007-02-13), pages 1969 - 1992, XP005886413, ISSN: 0264-410X, DOI: 10.1016/J.VACCINE.2006.11.051 * |
| MARY T LITZINGER ET AL: "IL-2 immunotoxin denileukin diftitox reduces regulatory T cells and enhances vaccine-mediated T-cell immunity", BLOOD, AMERICAN SOCIETY OF HEMATOLOGY, US, vol. 110, no. 9, 1 November 2007 (2007-11-01), pages 3192 - 3201, XP002628064, ISSN: 0006-4971, [retrieved on 20070706], DOI: 10.1182/BLOOD-2007-06-094615 * |
| MING-SHEN DAI ET AL: "Early Treg suppression by a listeriolysin-O-expressing E. coli vaccine in heterologous prime-boost vaccination against cancer", VACCINE, vol. 30, no. 48, 1 November 2012 (2012-11-01), pages 6903 - 6911, XP055079672, ISSN: 0264-410X, DOI: 10.1016/j.vaccine.2012.09.001 * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2014140938A2 (fr) | 2014-09-18 |
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