WO2016108507A3 - 멜라토닌 및 설트랄린을 포함하는 경구용 복합정제 - Google Patents

멜라토닌 및 설트랄린을 포함하는 경구용 복합정제 Download PDF

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Publication number
WO2016108507A3
WO2016108507A3 PCT/KR2015/014205 KR2015014205W WO2016108507A3 WO 2016108507 A3 WO2016108507 A3 WO 2016108507A3 KR 2015014205 W KR2015014205 W KR 2015014205W WO 2016108507 A3 WO2016108507 A3 WO 2016108507A3
Authority
WO
WIPO (PCT)
Prior art keywords
oral administration
sertraline
melatonin
composite tablet
pharmaceutically acceptable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/KR2015/014205
Other languages
English (en)
French (fr)
Other versions
WO2016108507A2 (ko
Inventor
조재평
서영대
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kuhnil Pharmaceutical Co Ltd
Original Assignee
Kuhnil Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kuhnil Pharmaceutical Co Ltd filed Critical Kuhnil Pharmaceutical Co Ltd
Publication of WO2016108507A2 publication Critical patent/WO2016108507A2/ko
Publication of WO2016108507A3 publication Critical patent/WO2016108507A3/ko
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

본 발명은 멜라토닌 또는 약제학적으로 허용 가능한 그의 염, 및 서방화제로서 겔형성 폴리머를 함유하는 서방층; 및 설트랄린 또는 약제학적으로 허용 가능한 그의 염을 함유하는 속방층을 포함하는, 경구용 복합정제 및 그 제조방법을 제공한다.
PCT/KR2015/014205 2014-12-31 2015-12-23 멜라토닌 및 설트랄린을 포함하는 경구용 복합정제 Ceased WO2016108507A2 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2014-0195829 2014-12-31
KR1020140195829A KR20160081646A (ko) 2014-12-31 2014-12-31 멜라토닌 및 설트랄린을 포함하는 경구용 복합정제

Publications (2)

Publication Number Publication Date
WO2016108507A2 WO2016108507A2 (ko) 2016-07-07
WO2016108507A3 true WO2016108507A3 (ko) 2016-08-25

Family

ID=56285117

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2015/014205 Ceased WO2016108507A2 (ko) 2014-12-31 2015-12-23 멜라토닌 및 설트랄린을 포함하는 경구용 복합정제

Country Status (3)

Country Link
KR (1) KR20160081646A (ko)
TW (1) TW201626990A (ko)
WO (1) WO2016108507A2 (ko)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4236940A4 (en) * 2020-10-30 2024-10-16 Nutriventia Limited MODIFIED RELEASE COMPOSITIONS COMPRISING MELATONIN
KR20250082168A (ko) * 2023-11-29 2025-06-09 동아제약 주식회사 멜라토닌을 포함하는 방출조절 경구투여용 제제 및 이의 제조방법

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006514688A (ja) * 2002-09-11 2006-05-11 エラン ファーマ インターナショナル，リミティド ゲル安定化ナノパーティクル活性物質組成物
KR100680574B1 (ko) * 2002-02-01 2007-02-08 데포메드 인코퍼레이티드 속방성 및 서방성 약물 모두를 송달하는 경구 투약 형태의제조방법
WO2008095142A1 (en) * 2007-01-31 2008-08-07 Methylation Sciences International Srl Extended release pharmaceutical formulations of s-adenosylmethionine

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100680574B1 (ko) * 2002-02-01 2007-02-08 데포메드 인코퍼레이티드 속방성 및 서방성 약물 모두를 송달하는 경구 투약 형태의제조방법
JP2006514688A (ja) * 2002-09-11 2006-05-11 エラン ファーマ インターナショナル，リミティド ゲル安定化ナノパーティクル活性物質組成物
WO2008095142A1 (en) * 2007-01-31 2008-08-07 Methylation Sciences International Srl Extended release pharmaceutical formulations of s-adenosylmethionine

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
KASIMAY, O. ET AL.: "Exogenous Melatonin Delays Gastric Emptying Rate.", JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, vol. 56, no. 4, 2005, pages 543 - 553 *
O'REARDON, J. P . ET AL.: "A Randomized, Placebo-controlled Trial of Sertraline in the Treatment of Night Eating Syndrome", AMERICAN JOURNAL OF PSYCHIATRY, vol. 163, no. 5, 2006, pages 893 - 898 *

Also Published As

Publication number Publication date
TW201626990A (zh) 2016-08-01
KR20160081646A (ko) 2016-07-08
WO2016108507A2 (ko) 2016-07-07

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