WO2016165587A1 - Échantillonneur d'urine jetable, pré-traité et auto-destructible et son procédé de fabrication - Google Patents

Échantillonneur d'urine jetable, pré-traité et auto-destructible et son procédé de fabrication Download PDF

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Publication number
WO2016165587A1
WO2016165587A1 PCT/CN2016/078849 CN2016078849W WO2016165587A1 WO 2016165587 A1 WO2016165587 A1 WO 2016165587A1 CN 2016078849 W CN2016078849 W CN 2016078849W WO 2016165587 A1 WO2016165587 A1 WO 2016165587A1
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Prior art keywords
sampling
urine
sampling tube
porous
microbubble
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PCT/CN2016/078849
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English (en)
Chinese (zh)
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戚本昊
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/10—Devices for withdrawing samples in the liquid or fluent state
    • G01N1/14—Suction devices, e.g. pumps; Ejector devices

Definitions

  • the invention relates to a urine sampler and a preparation method thereof, in particular to a urine sampler which is self-destructive for one-time pretreatment, can keep urine components stable for a certain period of time, and is convenient to use and store. And its production method.
  • the concentration of antibody in urine is much lower than that of blood antibody.
  • the total concentration of various antibodies in urine is 1/3000 of the concentration of blood antibody, and the concentration of HIV antibody is lower.
  • Urine mainly contains water, inorganic salts, urea and uric acid and trace creatinine, acid mucopolysaccharide, oxalic acid and metabolites of diet and ingested drugs, as well as extremely small amounts of antibody antigens, among which inorganic salts are equivalent to plasma and urea.
  • uric acid is 60 times and 11 times that of plasma, respectively.
  • the urine is separated from the human body, and the temperature and pH changes make the urine unstable, and it is easy to form flocculation and sediment, and reduce the concentration of antibodies (antigens) in the urine. Therefore, maintaining the stability of urine is the first step to ensure accurate urine component analysis and urine antibody (antigen) detection.
  • the urine contains a small amount of bacteria.
  • the urine is collected in a urine cup and the collection process is not aseptic.
  • the urine collected in the test tube is not easily stored for a long time.
  • the method of "urine cup collection - test tube storage" is susceptible to contamination and easy labeling disorder.
  • Another object of the present invention is to provide a method of fabricating the urine sampler.
  • a disposable pretreatment self-destructing urine sampler comprising a sampling head, a sampling tube, a porous microbubble sampling column and a suction member, the sampling head being located at a front end of the sampling tube, porous microbubbles a sampling column is located in the sampling tube, the suction member is disposed at an end of the sampling tube, and a suction member is connected to the porous microbubble sampling column 4, the porous microbubble sampling column is composed of pretreated porous microbubbles
  • the material is prepared by blocking the pretreated porous microbubble material with a protein or a surfactant, and then further treating the closed porous microbubble material with an antibacterial agent and an antifungal solution, and finally forming the porous microbubble Sampling column.
  • the porous microbubble material is a polymeric sponge material capable of absorbing solution, compressible and elastic, and not reactive with urine components.
  • the porous microbubble material has a micropore diameter of from 1 ⁇ m to 1 mm.
  • the suction member comprises a tie rod and a silicone rubber stopper, one end of the pull rod is fixed to the silicone rubber stopper, and the other end of the pull rod is extended outside the end of the sampling tube.
  • the tie rod and the silicone rubber stopper are glued and fixedly connected.
  • the drawbar is made of a material that is easy to break, or the drawbar is made of a material that facilitates the coding, or the drawbar is made of a material that is easy to break and facilitates spray numbering.
  • the drawbar is a flat wooden drawbar.
  • the sampling head is covered with a dust cap.
  • the sampling head is a screw head threadedly engaged with a front end of the sampling tube, and the screw head penetrates a through hole communicating with the sampling tube.
  • the urine sampler further comprises a fixing member for the fixing member
  • the suction member is restricted from extending beyond the end of the sampling tube.
  • the fixing member is a fixing nut threadedly engaged with the end of the sampling tube
  • the suction member comprises a tie rod and a silicone rubber stopper, one end of the rod is fixed to the silicone rubber stopper, and the other end of the rod extends outside the end of the sampling tube.
  • the fixing nut is screwed through the tie rod at the end of the sampling tube.
  • the pull rod is a flat pull rod
  • the fixing nut has a flat hole through which the flat rod passes.
  • the drawbar is a flat wooden drawbar.
  • the sampling tube and the suction member are sprayed with the same number.
  • the suction member comprises a pull rod and a silicone rubber plug, one end of the pull rod is fixed to the silicone rubber plug, and the other end of the pull rod is extended outside the end of the sampling tube, and the sampling tube and the pull rod are sprayed with the same number.
  • a disposable pretreatment self-destructive urine sampler wherein the sampler comprises a sampling head, a sampling tube, and a porous microbubble sampling column. And a suction member, the sampling head being located at a front end of the sampling tube, a porous microbubble sampling column being located in the sampling tube, the suction member being disposed at an end of the sampling tube, a suction member and a porous microbubble The sample column is connected, and the porous microbubble sample column is used for adsorbing urine.
  • a method for manufacturing the urine sampler includes the following steps:
  • a polymer sponge material capable of absorbing urine, compressible and elastic, and not reacting with urine components is selected as a material for preparing a porous microbubble sampling column;
  • the polymer sponge material is then pretreated with a protein or a surfactant to maintain the activity of the antibody in the urine;
  • the surface of the polymer sponge material after sealing is further treated with an antibacterial agent and an antifungal agent solution, so as to be suitable for storing urine samples for a longer period of time;
  • the pretreated multi-polymer sponge material is cut into a suitable size to obtain a porous microbubble sampling column;
  • the obtained porous microbubble sampling column is loaded into the sampling tube, and finally the sampling head is installed at the front end of the sampling tube, and the suction member connected to the porous microbubble sampling column is installed at the rear end of the sampling tube.
  • the pretreatment process for the polymer sponge material comprises:
  • the mixture is placed at room temperature 20 ° C - 30 ° C for more than 24h;
  • the invention comprises a sampler for a porous microbubble sampling column, and the urine collection is simple, hygienic and safe, ensuring urinary sterility and ensuring uniqueness; the pretreated porous microbubble material can store the urine at room temperature for one week.
  • Urine antibody (antigen) concentration and original urine during testing The liquid is basically equivalent, ensuring the accuracy of urine antibody (antigen) detection and the convenience of self-test and the uniqueness and privacy of the test transmitted to other units, providing a new method for urine collection and storage.
  • Figure 1 is a schematic view showing the structure of a urine sampler of the present invention
  • Figure 2 is a cross-sectional view of the sampling tube of the present invention.
  • a disposable pretreatment self-destructive urine sampler includes a sampling head 2, a sampling tube 3, a porous microbubble sampling column 4, and a suction member, and the sampling head 2 is located at the sampling.
  • the front end of the tube 3, the porous microbubble sampling column 4 is located in the sampling tube 3, the suction member is disposed at the end of the sampling tube 3, the suction member is connected to the porous microbubble sampling column 4, and the porous microbubble sampling column 4 is pretreated.
  • the porous microbubble material is prepared by pretreating the pretreated porous microbubble material with a protein or a surfactant, and then further treating the closed porous microbubble material with an antibacterial agent and an antifungal solution, and finally making the porous material.
  • the urine When the urine is collected, the urine enters the sampling tube 3 through the sampling head 2, and then the suction member is pulled, so that the micropore bubble sampling column 4 is flattened in the sampling tube 3, and the urine is adsorbed by the porous microbubble sampling column 4.
  • Preservation integration of urine collection and preservation, can avoid contact with excessive bacteria, and help to maintain the stability of urine components.
  • the protein is blocked with a surfactant or a surfactant.
  • the activity of the antibody such as urine can be maintained, so that the urine can also be kept consistent with the original urine component in the sampling tube, and the porous microbubble sampling column is pretreated with the antibacterial agent and the antifungal solution.
  • the surface of the material is suitable for storing urine samples for a longer period of time, ensuring the sterility of the urine and ensuring uniqueness, and is more conducive to improving the accuracy of subsequent urine component analysis and urine antibody (antigen) detection.
  • the porous microbubble material of the present embodiment is a polymer sponge material capable of absorbing solution, compressible and elastic, and not reacting with urine components, for example, using a sponge, so that the porous microbubble sampling column 4 can be suctioned. Under the driving of the components, the tube 3 is freely stretched and contracted, so that the urine fills the sampling tube 3 as much as possible.
  • the porous microbubble material has a micropore diameter of from 1 ⁇ m to 1 mm in order to prevent leakage of urine from the porous microbubble sampling column 4, thereby forming a good adsorption property for urine.
  • a porous microbubble sampling column which is conventionally used without the pretreatment, can also be used to adsorb urine.
  • the embodiment is as follows: a one-time pretreatment Destructive urine sampler, the sampler comprises a sampling head 2, a sampling tube 3, a porous microbubble sampling column 4 and a suction member, the sampling head 2 is located at the front end of the sampling tube 3, and the porous microbubble sampling column 4 Located in the sampling tube 3, the suction member is disposed at the end of the sampling tube 3, and the suction member is coupled to the porous microbubble sampling column 4 for adsorbing urine.
  • the urine is adsorbed and stored by the porous microbubble sampling column 4, and the integration of urine collection and storage can be realized, the contact with excessive bacteria can be avoided, the stability of the urine component can be maintained, and the urine component analysis of urine can be ensured.
  • the suction member of the present embodiment includes a tie rod 7 and a silicone rubber stopper 5, a tie rod One end of the rod 7 is fixed to the silicone rubber stopper 5, and the other end of the rod 7 is extended outside the end of the sampling tube 3.
  • the suction of the urine can be achieved by the pull rod 7 driving the silicone rubber stopper 5 to move outside the end of the sampling tube 3.
  • the tie rod 7 and the silicone rubber plug 5 are preferably fixedly connected by means of glue, and of course, they can be integrally formed or fixed by means of inserting and snapping.
  • the rod 7 is made of a material that is easy to be broken; and in order to facilitate the collection of the urine corresponding to the collected urine, the rod 7 is made of a material that facilitates the coding.
  • the tie rods 7 are made of a material that is easy to break and facilitates spray numbering, preferably a flat wooden tie rod, so that it is collected
  • the pull rod 7 can be broken to retain the numbered drawbar 7 for easy identification of urine.
  • the sampling head 2 of the embodiment is covered with a dust cap 1, which can also be used for dressing when testing urine samples. Urine test tube.
  • the sampling head 2 is a screw head which is screwed with the front end of the sampling tube 3, so that the rotating head can be conveniently installed on the front end of the sampling tube 3, and the screw head penetrates a through hole communicating with the sampling tube 3, The through hole is used for urine to pass through the sampling tube 3 when the suction member is sucked.
  • the urine sampler of the present embodiment further includes a fixing member for restricting the suction member from extending beyond the end of the sampling tube 3 when the suction member moves toward the end away from the end of the sampling tube 3.
  • the suction member will eventually be restrained by the fixed member to prevent bacterial contamination of the suction member from the sampling tube 3.
  • the fixing member described above is preferably a fixing screw that is threadedly engaged with the end of the sampling tube 3.
  • the female 6, correspondingly, the end of the sampling tube 3 is set to the screw opening 8, which facilitates the convenient installation of the fixing nut 6.
  • the suction member of the present example comprises a pull rod 7 and a silicone rubber stopper 5, one end of which is fixed to the silicone rubber stopper 5, and the other end of the pull rod 7 extends beyond the end of the sampling tube 3, and the pull rod 7 is convenient for hand-drawn, and the silicone rubber stopper 5 facilitates
  • the sampling tube 3 forms a vacuum suction negative pressure, thereby introducing urine into the sampling tube 3.
  • the fixing nut 6 of this example is screwed through the tie rod 7 to the end of the sampling tube 3.
  • the pull rod 7 is a flat pull rod
  • the fixing nut 6 has a flat hole through which the flat pull rod just passes, so that the rotation of the pull rod 7 can be restricted, which is favorable for suction stability.
  • the tie rod 7 of this embodiment is a flat wooden tie rod.
  • the sampling tube 3 and the suction member are sprayed with the same number, so that the hand held by the collector can correspond to the number on the sampling tube 3 to avoid label disorder.
  • the function is realized in that the suction member comprises a pull rod 7 and a silicone rubber plug 5, one end of the pull rod 7 is fixed to the silicone rubber plug 5, and the other end of the pull rod 7 is extended outside the end of the sampling tube 3, the sampling tube 3 and the pull rod 7 Spray the same number on the spray.
  • the top of the sampling tube 3 is immersed in the urine, and the wooden rod is pulled to drive the silicone rubber stopper 5 to suck the urine into the porous microbubble for sampling.
  • the porous microbubble material having a diameter of between one micron and one millimeter. Since the urine is absorbed into the microbubbles of the porous microbubble sampling column 4, the relative isolation cannot flow out, so that the liquid is relatively solidified, which is convenient for storage and transportation.
  • the microbubble wall is a closed surfaced hydrophobic structure, so that the surface can not adsorb proteins and make the water-soluble substances in the urine difficult to precipitate.
  • the relatively closed microbubble environment makes the urine pH stable, and the microbubble wall adsorbs antibacterial substances to maintain urine. Sterile, so that the concentration of antibodies (antigens) in the urine is kept stable during storage.
  • the silicone rubber stopper 5 closes the rear end of the sampling tube 3, and finally samples the dust cap 1 After the front section of the tube 3, the front section of the sampling tube 3 is closed.
  • the flat rod (not limited to the wood rod, any material that is easy to break and self-destruct and is suitable for spraying number) is broken and sent to the inspection or passed to other units for inspection.
  • the urine is difficult to evaporate in a relatively closed environment, and the total volume is constant, ensuring that the antibody (antigen) concentration is unchanged.
  • a method for manufacturing the urine sampler includes the following steps:
  • a polymer sponge material capable of absorbing urine, compressible and elastic, and not reacting with urine components is selected as a material for preparing a porous microbubble sampling column;
  • the polymer sponge material is then pretreated with a protein or a surfactant to maintain the activity of the antibody in the urine;
  • the surface of the polymer sponge material after sealing is further treated with an antibacterial agent and an antifungal agent solution, so as to be suitable for storing urine samples for a longer period of time;
  • the pretreated multi-polymer sponge material is cut into a suitable size to obtain a porous microbubble sampling column;
  • the obtained porous microbubble sampling column is loaded into the sampling tube, and finally the sampling head is installed at the front end of the sampling tube, and the suction member connected to the porous microbubble sampling column is installed at the rear end of the sampling tube.
  • the pretreatment process for the polymer sponge material includes:
  • the mixture is placed at room temperature 25 ° C for more than 24h, the temperature can also be selected within the range of 20 ° C - 30 ° C;
  • the temperature of the incubator can also be Choose from a range of 30-40 °C.
  • the structure and dimensions of the components of the urine sampler of this example are:
  • Dust cap length 54mm, tip outer diameter 11mm, inner diameter 11mm, open end outer diameter 13mm, inner diameter 11mm, wall thickness 1mm;
  • Screw head length 14mm, top outer diameter 8mm, inner diameter 2mm hole, hole length 10mm, open end outer diameter 11mm, inner diameter 10mm, inner thread length 4mm, pitch 0.5mm.
  • Sampling tube length 80mm, outer diameter 10mm, inner diameter 8mm, thread length 5mm at both ends, pitch 0.5mm;
  • Porous microbubble sampling column long 50mm, diameter 6mm, high density polymer sponge sample column.
  • Silicone rubber stopper length 15mm, diameter 7mm, one end has a flat groove length of 10mm, width 1.5mm.
  • the length of the extension is three rounds, the height is 0.8mm, the width is 1mm, the spacing is 4mm, and the first one is 3mm from the top.
  • Fixing nut length 14mm, tip outer diameter 10mm, inner through a flat hole length 10mm, flat hole section length 6mm, width 2mm. Opening end outer diameter 11mm, inner diameter 10mm, with a thread length of 4mm and a pitch of 0.5mm.
  • Flat wooden tie rod length 100mm, width 6mm, thickness 1.5mm, one end is round, one end is straight.
  • the production method is specifically as follows:
  • the flat end of the flat wood tie rod 7 is glued and fixedly connected to the groove of the silicone rubber stopper 5.
  • the screw head is screwed on the front end of the sampling tube 3, the porous microbubble sampling column 4 is placed in the sampling tube 3, and the silicone rubber stopper 5 to which the flat wooden rod 7 is attached is inserted, and the fixing nut 6 with the flat hole is worn.
  • the flat wooden tie rod 7 is screwed to the rear end of the sampling tube 3. The same number is applied to the large faces of the sampling tube 3 and the flat wood rod 7.
  • the porous microbubble sampling column was immersed in a blocking solution with protein and surfactant for 2 hours every 2 hours (by disposing 2 g of the blocking liquid bovine serum albumin 2%, and then adding 0.05 mol/l of carbonic acid) Shake 100ml of salt buffer, then place it in a special bottle for blocking liquid, shake it for 15 minutes, mix the solution to make the blocking solution), antibacterial agent (mainly containing sodium azide) and blocking solution (mainly Containing 0.01M PBS buffer solution, pH 7.2, 0.1% calf serum), after standing at room temperature for 2 hours, drain the antibacterial solution and blocking solution, pull back the flat wooden rod 7, put it into the sampling tube 3, and screw it on.
  • the nut 6 is covered with a dust cap 1 and is a finished product.
  • the urine collection method is specifically as follows:

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  • Life Sciences & Earth Sciences (AREA)
  • Hydrology & Water Resources (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

L'invention concerne un échantillonneur d'urine jetable, pré-traité et auto-destructible, qui comprend une tête d'échantillonnage (2), un tube d'échantillonnage (3), une colonne d'échantillonnage à micro-bulles poreuse (4) et un élément d'aspiration. La tête d'échantillonnage (2) est située à l'extrémité avant du tube d'échantillonnage (3). La colonne d'échantillonnage à micro-bulles poreuse (4) est située dans le tube d'échantillonnage (3). L'élément d'aspiration est agencé à l'extrémité terminale du tube d'échantillonnage (3). L'élément d'aspiration est relié à la colonne d'échantillonnage à micro-bulles poreuse (4). La colonne d'échantillonnage à micro-bulles poreuse (4) est faite en un matériau à micro-bulles poreux pré-traité, le pré-traitement étant destiné à fermer et à pré-traiter le matériau à micro-bulles poreux à l'aide d'une protéine et d'un tensioactif, à traiter ensuite le matériau à micro-bulles poreux fermé à l'aide d'un agent antibactérien et d'un agent antifongique, et, finalement, à fabriquer la colonne d'échantillonnage à micro-bulles poreuse (4). L'invention concerne également un procédé de fabrication de l'échantillonneur d'urine. Cette invention permet de surmonter les problèmes d'une urine portant des bactéries et de l'instabilité de composants lors du prélèvement et du stockage de l'urine.
PCT/CN2016/078849 2015-04-15 2016-04-08 Échantillonneur d'urine jetable, pré-traité et auto-destructible et son procédé de fabrication Ceased WO2016165587A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201510176247.3A CN104777012B (zh) 2015-04-15 2015-04-15 一种一次性预处理自毁型尿液采样器及其制作方法
CN201510176247.3 2015-04-15

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WO2016165587A1 true WO2016165587A1 (fr) 2016-10-20

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109628286A (zh) * 2019-01-15 2019-04-16 泰普生物科学（中国）有限公司 一种运输培养装置

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104777012B (zh) * 2015-04-15 2017-11-24 戚本昊 一种一次性预处理自毁型尿液采样器及其制作方法
CN111964976A (zh) * 2020-08-06 2020-11-20 沈阳农业大学 一种雄性动物采尿装置的制备方法

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0520408A2 (fr) * 1991-06-25 1992-12-30 Saliva Diagnostic Systems, Inc. Dispositif d'échantillonnage et système d'adéquation d'échantillon
US5393494A (en) * 1992-05-28 1995-02-28 Diasys Corporation Apparatus for drawing fluid sample, components thereof, and slide assembly for use therewith
CN1657899A (zh) * 2004-02-17 2005-08-24 陈格 干燥保存液体样品的方法和装置
CN1994224A (zh) * 2006-01-06 2007-07-11 张洪杰 一种抽吸式采血器
US20090202393A1 (en) * 2008-02-13 2009-08-13 Capitol Vial Inc. Fluid sample collection system
CN101611134A (zh) * 2006-09-06 2009-12-23 彼得·A·K·勇 利用对接机构的可靠自持式生物分子取样和运输系统
CN104777012A (zh) * 2015-04-15 2015-07-15 戚本昊 一种一次性预处理自毁型尿液采样器及其制作方法

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0520408A2 (fr) * 1991-06-25 1992-12-30 Saliva Diagnostic Systems, Inc. Dispositif d'échantillonnage et système d'adéquation d'échantillon
US5393494A (en) * 1992-05-28 1995-02-28 Diasys Corporation Apparatus for drawing fluid sample, components thereof, and slide assembly for use therewith
CN1657899A (zh) * 2004-02-17 2005-08-24 陈格 干燥保存液体样品的方法和装置
CN1994224A (zh) * 2006-01-06 2007-07-11 张洪杰 一种抽吸式采血器
CN101611134A (zh) * 2006-09-06 2009-12-23 彼得·A·K·勇 利用对接机构的可靠自持式生物分子取样和运输系统
US20090202393A1 (en) * 2008-02-13 2009-08-13 Capitol Vial Inc. Fluid sample collection system
CN104777012A (zh) * 2015-04-15 2015-07-15 戚本昊 一种一次性预处理自毁型尿液采样器及其制作方法

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109628286A (zh) * 2019-01-15 2019-04-16 泰普生物科学（中国）有限公司 一种运输培养装置

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