WO2017105161A3 - 피부 미백 활성을 갖는 펩타이드 및 이의 용도 - Google Patents

피부 미백 활성을 갖는 펩타이드 및 이의 용도 Download PDF

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Publication number
WO2017105161A3
WO2017105161A3 PCT/KR2017/001315 KR2017001315W WO2017105161A3 WO 2017105161 A3 WO2017105161 A3 WO 2017105161A3 KR 2017001315 W KR2017001315 W KR 2017001315W WO 2017105161 A3 WO2017105161 A3 WO 2017105161A3
Authority
WO
WIPO (PCT)
Prior art keywords
peptide
inhibiting
present
skin whitening
activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/KR2017/001315
Other languages
English (en)
French (fr)
Other versions
WO2017105161A2 (ko
Inventor
정용지
김은미
이응지
김잔디
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Caregen Co Ltd
Original Assignee
Caregen Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Caregen Co Ltd filed Critical Caregen Co Ltd
Priority to JP2017545262A priority Critical patent/JP6400857B2/ja
Priority to BR112017018838-4A priority patent/BR112017018838B1/pt
Priority to PCT/KR2017/001315 priority patent/WO2017105161A2/ko
Priority to EP17730342.7A priority patent/EP3275891B1/en
Priority to US15/553,693 priority patent/US10080775B2/en
Priority to CN201780000946.XA priority patent/CN108699114B/zh
Priority to ES17730342T priority patent/ES3052610T3/es
Publication of WO2017105161A2 publication Critical patent/WO2017105161A2/ko
Publication of WO2017105161A3 publication Critical patent/WO2017105161A3/ko
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/005—Enzyme inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

본 발명은 피부 미백 활성을 갖는 펩타이드를 제공한다. 본 발명의 멜라닌 생성을 억제하고, 티로시네이즈의 활성을 억제하며, 멜라닌 형성과 관련된 인자들의 발현을 억제하고, 멜라노좀 이동을 억제함으로써 피부 미백에 대하여 우수한 효과를 나타낸다. 본 발명의 펩타이드는 크기가 작기 때문에 피부 투과도가 매우 뛰어나다. 상술한 본 발명의 펩타이드의 우수한 활성 및 안정성은 화장품에 매우 유리하게 적용될 수 있다.
PCT/KR2017/001315 2015-12-18 2017-02-06 피부 미백 활성을 갖는 펩타이드 및 이의 용도 Ceased WO2017105161A2 (ko)

Priority Applications (7)

Application Number Priority Date Filing Date Title
JP2017545262A JP6400857B2 (ja) 2015-12-18 2017-02-06 皮膚美白活性を有するペプチド及びその用途
BR112017018838-4A BR112017018838B1 (pt) 2015-12-18 2017-02-06 Peptídeo possuindo atividade de branqueamento da pele, composição para branqueamento da pele, composição para inibição de crescimento de cabelo e seus usos
PCT/KR2017/001315 WO2017105161A2 (ko) 2015-12-18 2017-02-06 피부 미백 활성을 갖는 펩타이드 및 이의 용도
EP17730342.7A EP3275891B1 (en) 2015-12-18 2017-02-06 Peptide having skin whitening activity, and use thereof
US15/553,693 US10080775B2 (en) 2015-12-18 2017-02-06 Peptide having skin whitening activity, and use thereof
CN201780000946.XA CN108699114B (zh) 2015-12-18 2017-02-06 具有皮肤美白活性的肽及其用途
ES17730342T ES3052610T3 (en) 2015-12-18 2017-02-06 Peptide having skin whitening activity, and use thereof

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR10-2015-0182070 2015-12-18
KR1020150182070A KR101841742B1 (ko) 2015-12-18 2015-12-18 피부 미백 활성을 갖는 펩타이드 및 이의 용도
PCT/KR2017/001315 WO2017105161A2 (ko) 2015-12-18 2017-02-06 피부 미백 활성을 갖는 펩타이드 및 이의 용도

Publications (2)

Publication Number Publication Date
WO2017105161A2 WO2017105161A2 (ko) 2017-06-22
WO2017105161A3 true WO2017105161A3 (ko) 2017-08-10

Family

ID=59056906

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2017/001315 Ceased WO2017105161A2 (ko) 2015-12-18 2017-02-06 피부 미백 활성을 갖는 펩타이드 및 이의 용도

Country Status (7)

Country Link
US (1) US10080775B2 (ko)
EP (1) EP3275891B1 (ko)
JP (1) JP6400857B2 (ko)
KR (1) KR101841742B1 (ko)
CN (1) CN108699114B (ko)
ES (1) ES3052610T3 (ko)
WO (1) WO2017105161A2 (ko)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6787911B2 (ja) 2017-04-27 2020-11-25 ケアジェン カンパニー, リミテッドCaregen Co., Ltd. 皮膚美白活性を有するペプチド及びその用途
KR102265434B1 (ko) * 2019-08-20 2021-06-15 주식회사 케어젠 피부 미백 활성을 갖는 펩타이드 및 이의 용도
KR102265432B1 (ko) 2019-08-20 2021-06-15 주식회사 케어젠 피부 미백 활성을 갖는 펩타이드 및 이의 용도
KR102265435B1 (ko) * 2019-08-20 2021-06-15 주식회사 케어젠 피부 미백 활성을 갖는 펩타이드 및 이의 용도
CN113651875B (zh) * 2021-10-21 2022-01-28 南京莱昂生物科技有限公司 一种寡肽-34的合成方法
CN113995742B (zh) * 2021-10-22 2023-12-29 中国医学科学院皮肤病医院(中国医学科学院皮肤病研究所) 包含丙戊酸的美白组合物及其用途
KR102859707B1 (ko) * 2022-11-18 2025-09-17 (주)케어젠 피부 미백 활성을 갖는 펩타이드 및 이의 용도
KR20250054922A (ko) * 2023-10-16 2025-04-24 (주)케어젠 피부 미백 활성을 갖는 펩타이드 및 이의 용도
KR20250054924A (ko) * 2023-10-16 2025-04-24 (주)케어젠 피부 미백 활성을 갖는 펩타이드 및 이의 용도
WO2025084719A1 (ko) * 2023-10-16 2025-04-24 (주)케어젠 피부 미백 활성을 갖는 펩타이드 및 이의 용도
KR102823089B1 (ko) * 2025-01-21 2025-06-23 (주)더마펌 미백용 펩타이드 및 이를 포함하는 미백용 화장료 조성물

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001002527A (ja) * 1999-06-22 2001-01-09 Lion Corp 皮膚外用剤組成物
KR100840144B1 (ko) * 2007-05-17 2008-06-23 경상대학교산학협력단 미백 활성을 갖는 물질의 스크리닝 방법
KR100879239B1 (ko) * 2007-04-19 2009-01-16 (주)케어젠 Ｔｇｆｐ－ｃａｐ 펩타이드 및 그의 용도
KR101001156B1 (ko) * 2009-04-14 2010-12-15 (주)케어젠 형질전환 성장인자의 활성을 가지는 펩타이드 및 그의 용도
KR20150119741A (ko) * 2014-04-16 2015-10-26 (주)아모레퍼시픽 캐드헤린11 또는 n-캐드헤린 발현을 조절하는 피부 개선 물질 및 이를 스크리닝하는 방법

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101167285B1 (ko) * 2011-11-18 2012-07-23 에이앤펩주식회사 피부 미백 활성을 갖는 나이아신-펩타이드 및 그의 용도
US20140056835A1 (en) * 2012-08-24 2014-02-27 Ae Kyung Industrial Co., Ltd. Cosmetic composition for skin whitening comprising small molecule-peptide conjugate
WO2014074555A1 (en) * 2012-11-06 2014-05-15 CoLabs International Corporation Composition containing a cellulose derived capsule with a sunscreen
EP2990027A1 (en) 2014-09-01 2016-03-02 Institut Curie Skin whitening peptide agents
KR101572606B1 (ko) 2014-11-24 2015-11-27 강원대학교산학협력단 Sfrp5 유래의 펩타이드 및 이를 포함하는 피부 미백용 화장료 조성물

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001002527A (ja) * 1999-06-22 2001-01-09 Lion Corp 皮膚外用剤組成物
KR100879239B1 (ko) * 2007-04-19 2009-01-16 (주)케어젠 Ｔｇｆｐ－ｃａｐ 펩타이드 및 그의 용도
KR100840144B1 (ko) * 2007-05-17 2008-06-23 경상대학교산학협력단 미백 활성을 갖는 물질의 스크리닝 방법
KR101001156B1 (ko) * 2009-04-14 2010-12-15 (주)케어젠 형질전환 성장인자의 활성을 가지는 펩타이드 및 그의 용도
KR20150119741A (ko) * 2014-04-16 2015-10-26 (주)아모레퍼시픽 캐드헤린11 또는 n-캐드헤린 발현을 조절하는 피부 개선 물질 및 이를 스크리닝하는 방법

Also Published As

Publication number Publication date
US10080775B2 (en) 2018-09-25
JP6400857B2 (ja) 2018-10-03
ES3052610T3 (en) 2026-01-12
JP2018513114A (ja) 2018-05-24
US20180042981A1 (en) 2018-02-15
BR112017018838A2 (ko) 2018-04-17
EP3275891B1 (en) 2025-09-03
CN108699114A (zh) 2018-10-23
WO2017105161A2 (ko) 2017-06-22
EP3275891A4 (en) 2018-08-01
EP3275891A2 (en) 2018-01-31
KR101841742B1 (ko) 2018-03-27
CN108699114B (zh) 2021-10-26
KR20170073821A (ko) 2017-06-29

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