WO2017116884A1 - Système de massage par ionisation - Google Patents

Système de massage par ionisation Download PDF

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Publication number
WO2017116884A1
WO2017116884A1 PCT/US2016/067917 US2016067917W WO2017116884A1 WO 2017116884 A1 WO2017116884 A1 WO 2017116884A1 US 2016067917 W US2016067917 W US 2016067917W WO 2017116884 A1 WO2017116884 A1 WO 2017116884A1
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WO
WIPO (PCT)
Prior art keywords
electrode
skin
end effector
formulation
embedded
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2016/067917
Other languages
English (en)
Inventor
Kaye Brunson
Lilac Muller
Zane Bowman Allen MILLER
Vincenzo Casasanta
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LOreal SA
Original Assignee
LOreal SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US14/984,104 external-priority patent/US20170189670A1/en
Priority claimed from US14/984,133 external-priority patent/US10463531B2/en
Application filed by LOreal SA filed Critical LOreal SA
Priority to EP16882387.0A priority Critical patent/EP3397340A1/fr
Publication of WO2017116884A1 publication Critical patent/WO2017116884A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/007—Heating or cooling appliances for medical or therapeutic treatment of the human body characterised by electric heating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H23/00—Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms
    • A61H23/02—Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms with electric or magnetic drive
    • A61H23/0218—Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms with electric or magnetic drive with alternating magnetic fields producing a translating or oscillating movement
    • A61H23/0236—Percussion or vibration massage, e.g. using supersonic vibration; Suction-vibration massage; Massage with moving diaphragms with electric or magnetic drive with alternating magnetic fields producing a translating or oscillating movement using sonic waves, e.g. using loudspeakers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H7/00—Devices for suction-kneading massage; Devices for massaging the skin by rubbing or brushing not otherwise provided for
    • A61H7/001—Devices for suction-kneading massage; Devices for massaging the skin by rubbing or brushing not otherwise provided for without substantial movement between the skin and the device
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432—Anode and cathode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0472—Structure-related aspects
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/007—Heating or cooling appliances for medical or therapeutic treatment of the human body characterised by electric heating
    • A61F2007/0071—Heating or cooling appliances for medical or therapeutic treatment of the human body characterised by electric heating using a resistor, e.g. near the spot to be heated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/007—Heating or cooling appliances for medical or therapeutic treatment of the human body characterised by electric heating
    • A61F2007/0075—Heating or cooling appliances for medical or therapeutic treatment of the human body characterised by electric heating using a Peltier element, e.g. near the spot to be heated or cooled
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H2201/00—Characteristics of apparatus not provided for in the preceding codes
    • A61H2201/01—Constructive details
    • A61H2201/0119—Support for the device
    • A61H2201/0153—Support for the device hand-held
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H2201/00—Characteristics of apparatus not provided for in the preceding codes
    • A61H2201/01—Constructive details
    • A61H2201/0157—Constructive details portable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H2201/00—Characteristics of apparatus not provided for in the preceding codes
    • A61H2201/02—Characteristics of apparatus not provided for in the preceding codes heated or cooled
    • A61H2201/0207—Characteristics of apparatus not provided for in the preceding codes heated or cooled heated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H2201/00—Characteristics of apparatus not provided for in the preceding codes
    • A61H2201/02—Characteristics of apparatus not provided for in the preceding codes heated or cooled
    • A61H2201/0221—Mechanism for heating or cooling
    • A61H2201/0228—Mechanism for heating or cooling heated by an electric resistance element
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H2201/00—Characteristics of apparatus not provided for in the preceding codes
    • A61H2201/10—Characteristics of apparatus not provided for in the preceding codes with further special therapeutic means, e.g. electrotherapy, magneto therapy or radiation therapy, chromo therapy, infrared or ultraviolet therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H2201/00—Characteristics of apparatus not provided for in the preceding codes
    • A61H2201/10—Characteristics of apparatus not provided for in the preceding codes with further special therapeutic means, e.g. electrotherapy, magneto therapy or radiation therapy, chromo therapy, infrared or ultraviolet therapy
    • A61H2201/105—Characteristics of apparatus not provided for in the preceding codes with further special therapeutic means, e.g. electrotherapy, magneto therapy or radiation therapy, chromo therapy, infrared or ultraviolet therapy with means for delivering media, e.g. drugs or cosmetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H2201/00—Characteristics of apparatus not provided for in the preceding codes
    • A61H2201/12—Driving means
    • A61H2201/1207—Driving means with electric or magnetic drive
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H2201/00—Characteristics of apparatus not provided for in the preceding codes
    • A61H2201/16—Physical interface with patient
    • A61H2201/1683—Surface of interface
    • A61H2201/169—Physical characteristics of the surface, e.g. material, relief, texture or indicia
    • A61H2201/1695—Enhanced pressure effect, e.g. substantially sharp projections, needles or pyramids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H2201/00—Characteristics of apparatus not provided for in the preceding codes
    • A61H2201/50—Control means thereof
    • A61H2201/5023—Interfaces to the user
    • A61H2201/5043—Displays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H2201/00—Characteristics of apparatus not provided for in the preceding codes
    • A61H2201/50—Control means thereof
    • A61H2201/5058—Sensors or detectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H2201/00—Characteristics of apparatus not provided for in the preceding codes
    • A61H2201/50—Control means thereof
    • A61H2201/5058—Sensors or detectors
    • A61H2201/5084—Acceleration sensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H2207/00—Anti-cellulite devices

Definitions

  • the embedded electrode is connected to the end effector via a flexible arm.
  • the method further includes forming an electric field that creates a microcurrent in the portion of skin.
  • a formulation-specific electrode including: an electrode support portion; a conductive shorting layer disposed over a surface of the electrode support portion; and an electrode contact layer disposed over a surface of the conductive shorting layer and is configured to contact a skin surface of a user, wherein the electrode support portion is configured to function as a mechanical coupler and as an electrical connector to the conductive shorting layer.
  • the indicator sign is configured reveal one of a pattern or a color when the electrode contact layer is not optimal for the formulation.
  • a formulation-specific electrode in another embodiment, includes an electrode support portion; a set of interlaced conductive shorting layers and a set of electrically insulating layers disposed over a surface of the electrode support portion; and an electrode contact layer disposed over a surface of the set of conductive shorting layers, wherein the electrode support portion is configured to function as a mechanical coupler and as a multiple electrical connector to the set of conductive shorting layers, wherein each conductive shorting layer is electrically isolated from the others.
  • FIGURE 2F is a flowchart showing detail of electrical communication to the microcontroller according to a second embodiment of the invention.
  • FIGURE 4D shows an embodiment of the embedded electrode divided into multiple concentric electrodes
  • FIGURES 5C-E show schematic illustrations of a top view of different examples of embedded electrodes on the arm in accordance with the disclosed embodiments
  • FIGURES 6A and 6B depict, respectively, an unloaded condition and a loaded condition of the system against a portion of the skin or the treatment area;
  • FIGURE 10 is a diagram demonstrating use of chloride for anion flux pictorially.
  • any electrochemical system where any two electrodes are biased as anode and cathode when in contact to a common electrolyte; oxidation and reduction will most likely occur.
  • This effect is commonly observed for iontophoresis applications using inert or passivated electrodes such as stainless steel, graphite, platinum (Pt) or gold (Au).
  • a runaway pH change may cause mild to severe skin irritation, inhibit drifting of cations or anions into an epidermis layer of the skin due to altering of the skin's conductivity and permeability, as well as degrade the formulation.
  • a consumable formulation-specific electrode that presents an electrochemically appropriate surface to an iontophoresis application treatment area with respect to an electric circuit contact (e.g. hand, wrist, adjacent areas, etc.) and an accompanying active fonnulation.
  • the massage mode can be configured to deliver a massage or mechanical stimuli designed to increase cellular production of specific proteins and aid in relaxation of a user or subject.
  • the iontophoresis mode can enable infusion of actives in the presence of an applied electrical field.
  • the iontophoresis mode can enable removal of impurities in the presence of an applied electrical field.
  • the microcurrent mode can be configured to enable electrotherapy including cosmetic electrotherapy such as muscle toning, micro-lifting, etc.
  • the heat therapy mode can be configured to provide heat therapy, to enhance the infusion of actives or the removal of impurities, and to deliver a pleasurable experience.
  • the diagnostic mode can be configured to sense a property or parameter of the subject's skin.
  • mechanical stimuli e.g., applied cyclical strain, mechanical motion, applied strain, and the like
  • biomarker e.g., protein
  • a number of proteins within the skin can be regulated using, among other things, cyclical mechanical strain applied at particular frequencies using an end effector.
  • the cumulative effects of applying cyclical mechanical strain as disclosed include one or more anti-aging effects.
  • cutaneous cells will react to the stress by upregulating (increasing) production of certain proteins.
  • the character and duration of the stress will affect which proteins are upregulated and to what extent.
  • a system for mechanically stimulating a portion of skin at a motion frequency includes an appliance having a motor and an end effector operably coupled to the motor.
  • the end effector includes a plurality of embedded electrodes at which the end effector is configured to contact the portion of skin.
  • the plurality of embedded electrodes are located at a target distance from each other that is based on an inverse of a target motion frequency.
  • the motor is configured to move the end effector such that, when the motor is operating, the system has a resonant frequency based on the target motion frequency.
  • the end effector produces a cyclical stimulus within the portion of skin at about the target motion frequency.
  • an end effector for mechanically stimulating a portion of skin at a motion frequency includes a central portion that is couplable to a motor and an plurality of arms having a plurality of embedded electrodes at which the end effector is configured to contact the portion of skin.
  • the plurality of embedded electrodes are located at a target distance from each other that is based on an inverse of the motion frequency.
  • the end effector is configured such that, when the central portion is coupled to the motor and the motor is operating, the end effector has a resonant frequency based on the motion frequency.
  • a method of treating a portion of skin at a motion frequency using an appliance including a motor coupled to an end effector includes driving at a resonant frequency the end effector having a plurality of embedded electrodes located at a distance from each other that is based on an inverse of a target motion frequency and inducing a cyclical stimulus at about the target motion frequency within a portion of skin contacted by the plurality of embedded electrodes.
  • an end effector with a plurality of embedded electrodes is used for mechanically stimulating a portion of skin at a motion frequency where the embedded electrodes are located a target distance from each other that is based on an inverse of the motion frequency.
  • a system for mechanically stimulating a portion of skin at a motion frequency includes an appliance and an end effector with a plurality of embedded electrodes that are located a distance from each other that is based on an inverse of the motion frequency.
  • the disclosed embodiments include a handheld personal appliance or appliance that can be configured to concurrently or sequentially operate in an iontophoresis mode.
  • the iontophoresis mode can enable infusion of ionic actives in presence of an applied electrical field.
  • the iontophoresis mode can enable removal of impurities in presence of an applied electrical field.
  • composition of electrodes used in iontophoresis have been found to have substantial effect on the net outcome of percutaneous infusion for a given delivery load.
  • the present disclosure seeks to address the primary problem of creating optimal conditions for matching electrode materials and voltage/current profiles to deliver an effective dose of the active ingredient into the skin.
  • a product solution is described that accounts for the wide variability in formulations, electrodes, and voltage/current profiles.
  • the microcurrent mode can be configured to enable electrotherapy including cosmetic electrotherapy such as muscle toning, micro-lifting, etc.
  • electrotherapy application of a sufficient microcurrent between two or more electrodes can cause tightening of the underlying muscle or the skin.
  • the electrotherapy can evoke vasoconstriction, narrowing of the blood vessels, or vasodilation, expanding of the blood vessels.
  • the microcurrent mode can work in conjunction with the heat therapy mode to enhance or counter act the vasoconstriction effect or the vasodilation effect.
  • the microcurrent mode can also be configured for transcutaneous electrical nerve stimulation (TENS). For instance, for pain management or to induce muscle contractions as part of electrical muscle stimulation (EMS).
  • TESS transcutaneous electrical nerve stimulation
  • the diagnostic mode can be configured to sense a property or parameter of the subject's skin including one of an electrical property, a mechanical property, an electo- mechanical property such as elasticity or tightness, and a surface contour property such as in quantifying wrinkle abundance or depth.
  • the parameter of the skin can be one or more of the EDA properties of the skin.
  • the diagnostic mode can be configured to sense a property of the embedded electrode.
  • the diagnostic mode can be configured to sense a consumable electrode property such as a composition of a consumable electrode material or an effective remaining life of the composition.
  • FIGURE IE shows a perspective illustration of a representative system 10 in accordance with the disclosed embodiment in FIGURE I B.
  • FIGURE IF shows a perspective illustration of a representative system 10 in accordance with the disclosed embodiment in FIGURE 1 C.
  • the source of mechanical motion is a source of reciprocating motion.
  • the source of reciprocating motion produces motion at sonic frequencies.
  • the first source has a reciprocation rate of less than 1 kHz.
  • the first source has a reciprocation rate of less than 200 Hz.
  • the first source has a reciprocation rate of greater than 10 Hz.
  • the source of reciprocating motion has a reciprocation rate of 20 to 200 Hz.
  • the source of reciprocating motion has a reciprocation rate of 110 to 135 Hz.
  • FIGURES 2A-B show a flow diagram depicting high-level embodiments of the electrical circuit loops formed between the system 10 and the skin 80.
  • FIGURE 2 A shows a first embodiment of the electrical circuit (A) where the device head 1 10 is connected to the end effector 120 by electrical wiring 250, where in the embedded electrodes 130 on the end effector 120 are in electrical communication with the skin 80 and/or the treatment area 81.
  • the electrical wiring 250 can include wires, metal contacts, circuit board traces and the like.
  • the microcontroller 240 is supplied with power by the battery 230 and receives the data measured by the sensor 260.
  • the microcontroller 240 also receives on/off commands and programming from die button 1 1 1 actuated by the subject.
  • the button 1 1 1 may be mechanical or tactile.
  • the microcontroller 240 can also be configured to cause the display of information on a screen or an indicator so that the subject can see the operating mode of the appliance 100.
  • the end effector 120 is shown including a central support 321 on the opposite side of the central portion 121. As is seen in FIGURE 3C, the arms 122 are located on portions of end effector 120 that are cantilevered out from the central support 321 . When the end effector 120 is made of a non- rigid material and the arms 122 are located on portions of end effector 120 that are cantilevered out from the central support 321 , the portions of end effector 120 with the arms 122 have a spring-like quality that permits some movement of the arms 122 in the Z- direction.
  • the iontophoresis mode can enable infusion of ionic actives in presence of an applied electrical field.
  • Each of the embedded electrodes 130 can infuse actives.
  • the iontophoresis mode can enable removal of impurities in presence of an applied electrical field.
  • the current delivered is a function of the applied voltage and the electrical resistance of the subject, a high enough current was not able to be generated to pass the perception threshold in certain subjects.
  • the maximum output voltage was reached before crossing a subject's perception threshold, the final current in mA was recorded.
  • the current output went above the 0.5 mA/cm 2 recommended limit, the experiment was terminated.
  • the formulations described herein are one or more of a cosmetic composition (e.g., makeup, foundation, bronzer, etc.), a medical ointment (e.g., antibacterial ointment, hydrocortisone cream, etc.), a cleanser (e.g., soap, makeup remover, etc.), or any other composition that is capable of being applied to a portion of skin.
  • the formulation is a liquid, a non-Newtonian substance, a gel, or any other type of composition.
  • the formulation can be configured for uses such as skin care, skin cleansing, skin purification, skin exfoliation, skin desquamation, massage, cellulite, thinning, make up, and depigmentation.
  • Integral to the effective function of the appliance 100 is an appropriately formulated topical solution that contains the ionic form of active ingredients desired.
  • the formulation is positioned between the subject's skin and each embedded electrode.
  • the formulation is applied to the device head 1 10 prior to contacting the subject's skin.
  • the formulation is applied to the location on the subject's skin prior to the steps of directing the sonic motion and directing the ultrasonic motion.
  • the formulation improves action between the location and the first source of oscillatory motion.
  • the formulation improves action between the location and the second source of oscillatory motion.
  • the appliance 100 includes a formulation reservoir configured to deliver the formulation between the subject's skin and the first electrode.
  • the formulation can have a pH and ion concentration (both active and competing) to maximize the flux of the active into the epidermis.
  • the formulation includes a charged species of an active ingredient selected from the group comprising of analgesics, anesthetics, anti-inflammatories, anticoagulants, therapeutic peptides, oligonucleotides, and cosmetic actives.
  • Preferred depigmenting agents include vitamin C and its derivatives and especially vitamin CG, CP and 3-0 ethyl vitamin C, alpha and beta arbutin, ferulic acid, kojic acid, resorcinol and derivatives, D pantheteine calcium sulfonate, lipoic acid, ellagic acid, vitamin B3, a water kiwi fruit (Actinidia chinensis) marketed by Gattefosse, an extract of Paeonia suffruticosa root, such as that sold by the company Ichimaru Pharcos under the name Botanpi Liquid B.
  • the formulation includes an anti-wrinkle active.
  • anti-wrinkle active refers to a natural or synthetic compound producing a biological effect, such as the increased synthesis and / or activity of certain enzymes, when brought into contact with an area of wrinkled skin, this has the effect of reducing the appearance of wrinkles and/or fine lines.
  • adenosine derivatives include especially non-phosphate derivatives of adenosine, such as in particular the 2'-deoxyadenosine, 2',3'-adenosine isopropoylidene; the toyocamycine, 1-methyladenosine, N-6-methyladenosine; adenosine N-oxide, 6- methylmercaptopurine riboside, and the 6-chloropurine riboside.
  • non-phosphate derivatives of adenosine such as in particular the 2'-deoxyadenosine, 2',3'-adenosine isopropoylidene; the toyocamycine, 1-methyladenosine, N-6-methyladenosine; adenosine N-oxide, 6- methylmercaptopurine riboside, and the 6-chloropurine riboside.
  • adenosine receptor agonists including adenosine adenosine phenylisopropyl ("PIA"), 1- methylisoguanosine, N6-cyclohexyladenosine (CHA), N6-cyclopentyladenosine (CPA), 2 - chloro-N6-cyclopentyladenosine, 2-chloroadenosine, N6-phenyladenosine, 2- phenylaminoadenosine, MECA, N 6-phenethyladenosine, 2-p-(2-carboxy-ethyl) _ phenethyl- amino-5'- -N-ethylcarboxamido adenosine (CGS-21680), N-ethylcarboxamido-adenosine (NECA), the 5 '(N-cyclopropyl)-carboxamidoadenosine, DPMA (PD 129.944)
  • adenosine derivatives include compounds that increase the intracellular concentration of adenosine, such as erythro-9-(2-hydroxy-3-nonyl) adenine ("EHNA”) and iodotubercidine.
  • EHNA erythro-9-(2-hydroxy-3-nonyl) adenine
  • Others adenosine derivatives include salts and alkyl esters.
  • An active promoting skin microcirculation assets acting on the cutaneous microcirculation can be used to avoid dulling of the complexion and / or improve the appearance of the eye contour, in particular to reduce dark circles.
  • the active may for example be selected from an extract of maritime pine bark as Pycnogenol (R) from Bio prises, manganese gluconate (GIVOBIO GMn Seppic), an extract of Ammi Visnaga as Visnadine of Indena, lupine extract (Eclaline Silab), the coupling protein hydrolyzed wheat / palmitic acid with palmitic acid as Epaline 100 Carilene Laboratories, the extract of bitter orange blossom (Remoduline Silab) vitamin P and its derivatives such as methyl-4 monoethanoate esculetol sodium sold under the name Permethol Sephytal, extracts of ruscus, brown guinea, ivy, sweet clover and ginseng, caffeine nicotinate and derivatives thereof, lysine and its derivatives such as
  • the formulation includes an active ingredient that addresses oily skin.
  • actives can be sebo-regulating or antiseborrhoeic agents capable of regulating the activity of sebaceous glands. These include: retinoic acid, benzoyl peroxide, sulfur, vitamin B6 (pyridoxine or) chloride, selenium, samphire - the cinnamon extract blends, tea and octanoylglycine such as - 15 Sepicontrol A5 TEA from Seppic - the mixture of cinnamon, sarcosine and octanoylglycine marketed especially by Seppic under the trade name Sepicontrol A5 - zinc salts such as zinc gluconate, zinc pyrrolidonecarboxylate (or zinc pidolate), zinc lactate, zinc aspartate, zinc carboxylate, zinc salicylate 20, zinc cysteate; - derivatives particularly copper and copper pidolate as Cuivridone Solabia - extracts from plants of
  • the anti-seborrhoeic active agent is chosen from: zinc salts such as zinc gluconate, zinc pyrrolidonecarboxylate (or zinc pidolate), zinc lactate, zinc aspartate, carboxylate zinc, zinc salicylate, zinc cysteate, and preferably pyrrolidonecarboxylate zinc (or Pidolate zinc) or zinc salicylate - the clove extract such as that sold under the name Clove extract powder by Maruzen - glycine grafted onto an undecylenic chain, such as that sold under the name Lipacide UG OR by SEPPIC - trialkyl citrate (C 12-C13) sold under the name COSMACOL ECI by Sasol trialkyl citrate (C14-C15) sold under the name COSMACOL 5 ECL by Sasol - and mixtures thereof.
  • zinc salts such as zinc gluconate, zinc pyrrolidonecarboxylate (or zinc pidolate), zinc lactate, zinc aspartate, carb
  • Antiseborrhoeic active is, for example, present in an amount ranging from 0.1 to 10% by weight, preferably 0.1 to 5% by weight, and preferably from 0.5% to 3% by weight, relative to the total weight of the formulation.
  • any two metal electrodes are biased as anode and cathode when in contact to a common electrolyte; oxidation and reduction will most likely occur.
  • the anode will oxidize and the cathode will reduce.
  • the cathode will reduce 2(H + + OH ⁇ ) ⁇ H 2 + 2(OH ⁇ ) to bubble hydrogen and locally increase the pH.
  • Silver/silver chloride electrodes can be produced by a variety of methods. One common method is the immersion of a Ag metal finished surface into HQ and/or KG and the application of current. Thin mixed electrodes such as this, are common consumables in medical iontophoresis.
  • the alkali ion is the mobile species responsible for the valence changes - in that they can reduce upon entry and oxidize upon exit. If M represents the alkali and A the matrix, the reversible half reactions are: Mx+y Y ⁇ xM + +MyA + e ⁇ This solution is attractive if a given formulation will not accommodate CI " or other anions for Ag/AgCl -but will allow an alkali ion flux.
  • the bead 410 can be made from a low cost and disposable plastic or any commodity polymer material.
  • the bead's outer surface is layered with the conductive shorting layer 420 such as a thin layer of electrochemically compatible metal, salt, compound, or polymer.
  • the conductive shorting layer 420 allows contact with external circuitry such as the electrical system 200 and also serves to promote adhesion of the electrode contact surface layer 430.
  • the electrode contact surface layer 430 is made of an appropriate formulation-specific material. In one example the electrode contact surface layer 430 is Trivalent Chromium.
  • the concentric electrode system 450 is divided into four concentric electrodes 451 , 452, 453, and 454 where the two outermost concentric electrodes 451 , 452 can be used to drive a voltage, the second concentric electrode from the center 453 can be used as a guard electrode, and the center concentric electrode 454 can be used as a current sink or the ground electrode.
  • the guard electrode acts to divert or sink a current flow along the skin that could lead to a hot spot. By using the guard electrode, current is forced to follow a deeper path through the skin tissue.
  • the concentric electrode system 450 can be configured to be used in the diagnostic mode for sensing or monitoring any of the parameters of the skin or biomarkers in one or more depths of the skin layers.
  • FIGURE 5 A shows a schematic illustration of a cross-section of an arm 122A of a representative end effector 120 in accordance with the disclosed embodiment in FIGURE 3B.
  • the arm 122A is shown having at least one embedded electrode 130 and electrical wiring 250 configured to communicate with the electrical system 200.
  • the arm 122 can have one or more complementary attachment features 510 for both electrical and mechanical connection to the embedded electtode 130.
  • the attachment feature 510 has a female 2016/067917 receiving shape.
  • FIGURE 5B shows a schematic illustration of a cross-section of an arm 122B of a representative end effector 120 in accordance with the disclosed embodiment in FIGURE 3B, where the arm 122B includes an attaclnnent feature 510 having a male receiving shape.
  • the moment of inertia of each arm 122 can be varied by modifying its center of mass.
  • the center of mass of the arm 122 can be modified according to several scenarios.
  • the embedded electrodes 130 can have different densities such that an embedded electrode 130 with a differing weight changes the center of mass of the arm 122.
  • the embedded electrode 130 can be placed at different positions along the arm 122, thereby changing the center of mass of the arm 122.
  • the system 10 is in an unloaded state (i.e., the end effector 120 is not in contact with the portion of the skin 80).
  • the appliance includes a motor that moves the end effector 120.
  • the motor imparts oscillating movements to the end effector 120 about an axis 610.
  • the system 10 has a resonant frequency based on a desired motion frequency.
  • the motion frequency is selected based on an anti-aging effect stimulated by a cyclical stimulus within the portion of skin at the motion frequency.
  • the end effector 120 has a cupped shape where the embedded electrodes 130 are located closer to the treatment area 81 than the central portion 121. From the point shown in FIGURE 6A, as the system 10 is lowered to the treatment area 81 , the embedded electrodes 130 are the first potions of the system 10 to contact the portion of the skin 80.
  • a force 620 is applied to the system 10 to bias the end effector 120 toward the portion of the skin 80 or the treatment area 81.
  • the force 620 applied to the system 10 is in a range from about 85 grams-force (approximately 0.83 N) to about 100 grams-force (approximately 0.98 N).
  • the force 620 applied to the system 10 causes the cantilevered portions of the end effector 120 to deflect toward the appliance 1 10. Such a deflection of the cantilevered portions is possible, in some examples, because the cantilevered portions of the end effector 120 are made of a non-rigid material.
  • the force 620 does not cause the central portion 121 to touch the treatment area 81.
  • the arms 122 remain in contact with the treatment area 81 when the force 620 is applied. Any contact of the end effector 120 with the treatment area 81 , other than the contact between the arms 122 and the end effector 120, may disrapt any cyclical stimulus of the treatment area 81 by the end effector 120.
  • FIGURE 6D shows the system 10 operating in the heating mode with heat waves 640 radiating toward the skin 80 and the treatment area 81.
  • the heat therapy mode can be configured to provide heat therapy, to enhance the infusion of actives or the removal of impurities, and to deliver a pleasurable experience.
  • the appliance 100 advantageously includes the heating element.
  • the heating element can be any source of heat to provide heat waves 640 and may include a heating resistor or a thermoelectric element or an infrared source.
  • the heating element includes an infrared source or a resistor.
  • the heating element can modify the temperature of an external surface of the end effector 120 and/or of the treatment area 81 and/or to transmit energy to the external surface of the end effector 120 and/or to the treatment area 81.
  • An external part of the appliance 100 can serve to guide the infrared radiation towards the end effector 120.
  • the electrical system 200 may include at least one button 11 1 which is connected in series with the heating element and is configured to modify the power to the heating element and to control the amount of heat.
  • FIGURE 7A depicts a side view of an embodiment of a contact area 700.
  • the contact area includes a smooth face 702 and a rounded shoulder 704.
  • the smooth face 702 includes a contact location that is configured to contact a portion of skin.
  • the rounded shoulder 704 has a radius that does not provide a noticeable edge to the face 702.
  • FIGURE 7C depicts a side view of an embodiment of a contact area 706.
  • the contact area includes a smooth face 708 and a rounded shoulder 710.
  • the smooth face 708 when used in an end effector with a plurality of arms, the smooth face 708 includes a contact location that is configured to contact a portion of skin.
  • the rounded shoulder 710 has a radius that provides a noticeable edge to the face 708. In the embodiments shown in FIGURES 7A and 7C, the radius of the rounded shoulder 710 is less than the radius of the rounded shoulder 704.
  • FIGURE 7D depicts a chart showing an example of skin displacement ⁇ 2 of a portion of skin over time when the portion of skin is in contact with the contact area 706 and the contact area 706 produces a cyclical stimulus within the portion of skin.
  • FIGURES 7E and 7F depict cross-sectional views of two embodiments of arms with slits across faces of the arms.
  • FIGURE 7E depicts a cross-sectional view of a contact area 712 that has a face 714.
  • the contact area 712 also has two slits 716 across the face 714.
  • FIGURE 7F depicts a cross-sectional view of a contact area 720 that has a face 722.
  • the contact area 720 also has two slits 724 across the face 722. While the embodiment of contact area 722 has two slits, in other embodiments, arms have other numbers of slits, such as one slit across the face. Between the two slits 724, a portion 726 of the contact area 720 is raised above the deepest parts of the two slits 724, but is recessed back from the level of the face 722. The recess in the face 722 created by the slits 724 and the recessed portion 726 is capable of containing treatment composition as the contact area 720 is moved across a portion of skin.
  • FIGURES 7G and 7H depict side views of embodiments of arms with surface texturing on their faces.
  • FIGURE 7G depicts a side view of a contact area 728.
  • the contact area 728 includes a face 730 with surface texturing in the form of dimples 732 on the face 730.
  • FIGURE 7H depicts a side view of a contact area 734.
  • the contact area 734 includes a face 736 with surface texturing in the form of linear bumps 738 on the face 736.
  • other forms of surface texturing are used on the faces of arms. Examples of the benefits of surface texturing on the face of a contact area include one or more of better application of treatment composition into a portion of skin, greater skin displacement by the contact area, or improved sensation of the operation of the contact area against the portion of skin.
  • FIGURES 8 A through 8D depict top views of embodiments of end effectors 120 with different shapes of the central portion 121 , different numbers and arrangements of the arms 122, and different numbers and arrangements of the embedded electrode 130.
  • Each of FIGURES 8 A through 8D depicts a top view of an end effector 120A-D resulting in a different electrode assembly 140.
  • Each end effector 120A-D includes a plurality of embedded electrodes 130A-D.
  • Each of the embedded electrodes 130A-D is located on one of a plurality of arms 122A-D.
  • the end effectors 120A-D have different numbers and arrangements of arms 122A- D. More specifically, as depicted in FIGURE 8 A, the end effector 120A has a flower arrangement with a circular central portion 121 A and six circular arms 122A around the circular central portion 121 A. As depicted in FIGURE 8B, the end effector 120B has an arrangement that is a variation of a flower arrangement. The end effector 120B has a circular central portion 121 B and eight pointed arms 122B around the circular central portion 121B. The embedded electrode 130B is shown with a non-spherical shape.
  • the end effector 120C has a butterfly arrangement with a central portion 121C with a vesica piscis shape and four anns 122C.
  • the four arms 122C are arranged with two sets of two arms 122C on each side of the central portion 121C.
  • the end effector 120D has a pie-shaped arrangement with a circular central portion 12 IB and six pie-piece-shaped arms 122D around the circular central portion 12 ID. Many other variations on the number and arrangement of arms 122 on an end effector 120 are possible.
  • Each of the embodiments of end effectors 120A-D depicted in FIGURES 8 A through 8D include a plurality of embedded electrodes 130A-D.
  • the embedded electrodes 130A-D are located at a target distance from each other that is based on an inverse of the motion frequency. It may not be possible to locate four or more embedded electrodes equidistantly from each other. For example, with four embedded electrodes located at corners of a square, an embedded electrode may be equidistantly located from the other embedded electrodes at neighboring corners, but will not be equidistantly located from the embedded electrode that is across the diagonal of the square.
  • FIGURE 9A shows an embodiment of the end effector 120 that can be adjusted to change the spatial distribution of the electrode assembly 140.
  • FIGURE 9B shows a change in the end effector 120 position relative to the skin due to a rotation of the end effector 120.
  • the alteration between modes is interlaced at a frequency such that the modes can be perceived by the subject to be simultaneous.
  • the polarity of each embedded electrode 130 can change in coordination with the interlaced modes. The polarity change can be done at the frequency or pattern of the mechanical motion, at a harmonic of that frequency or pattern, or a separate frequency or pattern.
  • the oscillatory or reciprocating mechanical motion can result in the end effector 120 having different spatial distances between each embedded electrode 130 and/or different spatial locations on the subject's skin.
  • a distance between each embedded electrode 130 and a location on the subject's skin can be varied such that a different optimal voltage/current profile should be applied.
  • the voltage or current profile can be configured to account for the spatial differences resulting due to the mechanical movement relative to the skin.

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rehabilitation Therapy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Electrotherapy Devices (AREA)

Abstract

L'invention concerne un système et une électrode spécifique à une formulation permettant la stimulation d'une partie de la peau. Le système comprend au moins deux électrodes, un moteur et un système électrique, le système électrique comprenant une source d'alimentation et un effecteur terminal étant couplé de manière fonctionnelle au moteur et au système électrique, l'effecteur terminal ayant au moins une électrode intégrée, parmi les deux ou plus de deux électrodes, disposée et couplée de manière fonctionnelle au système électrique au niveau duquel l'effecteur terminal est conçu pour être en communication électrique avec la partie de la peau, le moteur étant conçu pour soumettre l'effecteur terminal à des mouvements répétitifs tout en étant en contact avec la peau pour fournir une stimulation mécanique à la peau, la ou les électrodes intégrées étant conçues pour servir d'électrode source et l'autre des deux ou plus de deux électrodes étant conçue pour servir d'électrode de retour, la source d'alimentation étant conçue pour solliciter l'électrode source vers l'électrode de retour et pour former un champ électrique avec la partie de la peau.
PCT/US2016/067917 2015-12-30 2016-12-21 Système de massage par ionisation Ceased WO2017116884A1 (fr)

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US14/984,104 US20170189670A1 (en) 2015-12-30 2015-12-30 Iontophoresis electrodes
US14/984,104 2015-12-30
US14/984,133 US10463531B2 (en) 2015-12-30 2015-12-30 Iontophoresis massager
US14/984,133 2015-12-30

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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110236917A (zh) * 2019-06-18 2019-09-17 温州市人民医院 腿部肌肉按摩装置
USD891628S1 (en) * 2015-03-03 2020-07-28 Carol Cole Company Skin toning device
CN112295102A (zh) * 2020-11-20 2021-02-02 株式会社Jnl 一种三合一美容仪
USD949358S1 (en) 2018-05-15 2022-04-19 Carol Cole Company Elongated skin toning device
USD953553S1 (en) 2020-02-19 2022-05-31 Carol Cole Company Skin toning device
USD957664S1 (en) 2020-07-29 2022-07-12 Carol Cole Company Skin toning device
WO2022239876A1 (fr) * 2021-05-12 2022-11-17 Kwang Chun Kim Appareil de thérapie par ions pour le traitement causal de l'hépatite, du diabète et de l'obésité
KR102825623B1 (ko) * 2024-04-23 2025-06-27 주식회사 더마하 반지괄사기

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5395310A (en) * 1988-10-28 1995-03-07 Alza Corporation Iontophoresis electrode
US6115625A (en) * 1999-02-08 2000-09-05 Axelgaard Manufacturing Co., Ltd. Medical electrode
KR100768898B1 (ko) * 2006-05-19 2007-10-19 (주)닥터스텍 피부 미용 장치
US7427273B2 (en) * 2004-03-01 2008-09-23 Japan Natural Laboratory Co., Ltd. Skin beautification cosmetic system using iontophoresis device, ultrasonic facial stimulator, and cosmetic additive
US20150265825A1 (en) * 2014-03-21 2015-09-24 L'oreal Combined sonic and iontophoretic skin care device

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5395310A (en) * 1988-10-28 1995-03-07 Alza Corporation Iontophoresis electrode
US6115625A (en) * 1999-02-08 2000-09-05 Axelgaard Manufacturing Co., Ltd. Medical electrode
US7427273B2 (en) * 2004-03-01 2008-09-23 Japan Natural Laboratory Co., Ltd. Skin beautification cosmetic system using iontophoresis device, ultrasonic facial stimulator, and cosmetic additive
KR100768898B1 (ko) * 2006-05-19 2007-10-19 (주)닥터스텍 피부 미용 장치
US20150265825A1 (en) * 2014-03-21 2015-09-24 L'oreal Combined sonic and iontophoretic skin care device

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USD1054571S1 (en) 2015-03-03 2024-12-17 Carol Cole Company Skin toning device
USD891628S1 (en) * 2015-03-03 2020-07-28 Carol Cole Company Skin toning device
USD959005S1 (en) 2018-05-15 2022-07-26 Carol Cole Company Elongated skin toning device
USD949358S1 (en) 2018-05-15 2022-04-19 Carol Cole Company Elongated skin toning device
CN110236917A (zh) * 2019-06-18 2019-09-17 温州市人民医院 腿部肌肉按摩装置
USD953553S1 (en) 2020-02-19 2022-05-31 Carol Cole Company Skin toning device
USD1047175S1 (en) 2020-02-19 2024-10-15 Carol Cole Company Head of a skin toning device
USD957664S1 (en) 2020-07-29 2022-07-12 Carol Cole Company Skin toning device
USD1017822S1 (en) 2020-07-29 2024-03-12 Carol Cole Company Skin toning device
CN112295102A (zh) * 2020-11-20 2021-02-02 株式会社Jnl 一种三合一美容仪
CN112295102B (zh) * 2020-11-20 2025-05-27 株式会社Jnl 一种三合一美容仪
WO2022239876A1 (fr) * 2021-05-12 2022-11-17 Kwang Chun Kim Appareil de thérapie par ions pour le traitement causal de l'hépatite, du diabète et de l'obésité
KR102825623B1 (ko) * 2024-04-23 2025-06-27 주식회사 더마하 반지괄사기

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