WO2017132646A1 - Systèmes de transport osseux - Google Patents
Systèmes de transport osseux Download PDFInfo
- Publication number
- WO2017132646A1 WO2017132646A1 PCT/US2017/015555 US2017015555W WO2017132646A1 WO 2017132646 A1 WO2017132646 A1 WO 2017132646A1 US 2017015555 W US2017015555 W US 2017015555W WO 2017132646 A1 WO2017132646 A1 WO 2017132646A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- bone
- adjustable
- housing
- implant
- rod
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
- A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
- A61B17/72—Intramedullary devices, e.g. pins or nails
- A61B17/7216—Intramedullary devices, e.g. pins or nails for bone lengthening or compression
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
- A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
- A61B17/72—Intramedullary devices, e.g. pins or nails
- A61B17/7216—Intramedullary devices, e.g. pins or nails for bone lengthening or compression
- A61B17/7225—Intramedullary devices, e.g. pins or nails for bone lengthening or compression for bone compression
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
- A61B17/60—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements for external osteosynthesis, e.g. distractors, contractors
- A61B17/62—Ring frames, i.e. devices extending around the bones to be positioned
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
- A61B17/60—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements for external osteosynthesis, e.g. distractors, contractors
- A61B17/66—Alignment, compression or distraction mechanisms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
- A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
- A61B17/80—Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates
- A61B17/8004—Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates with means for distracting or compressing the bone or bones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
- A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
- A61B17/80—Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates
- A61B17/8004—Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates with means for distracting or compressing the bone or bones
- A61B17/8019—Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates with means for distracting or compressing the bone or bones where the means are a separate tool rather than being part of the plate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/16—Instruments for performing osteoclasis; Drills or chisels for bones; Trepans
- A61B17/17—Guides or aligning means for drills, mills, pins or wires
- A61B17/171—Guides or aligning means for drills, mills, pins or wires for external fixation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
- A61B17/60—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements for external osteosynthesis, e.g. distractors, contractors
- A61B17/64—Devices extending alongside the bones to be positioned
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
- A61B17/88—Osteosynthesis instruments; Methods or means for implanting or extracting internal or external fixation devices
- A61B17/8866—Osteosynthesis instruments; Methods or means for implanting or extracting internal or external fixation devices for gripping or pushing bones, e.g. approximators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B2017/00367—Details of actuation of instruments, e.g. relations between pushing buttons, or the like, and activation of the tool, working tip, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B2017/00367—Details of actuation of instruments, e.g. relations between pushing buttons, or the like, and activation of the tool, working tip, or the like
- A61B2017/00398—Details of actuation of instruments, e.g. relations between pushing buttons, or the like, and activation of the tool, working tip, or the like using powered actuators, e.g. stepper motors, solenoids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B2017/00367—Details of actuation of instruments, e.g. relations between pushing buttons, or the like, and activation of the tool, working tip, or the like
- A61B2017/00398—Details of actuation of instruments, e.g. relations between pushing buttons, or the like, and activation of the tool, working tip, or the like using powered actuators, e.g. stepper motors, solenoids
- A61B2017/00402—Piezo electric actuators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B2017/00831—Material properties
- A61B2017/00876—Material properties magnetic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
- A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
- A61B2017/681—Alignment, compression, or distraction mechanisms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
Definitions
- the present disclosure further provides for a method for transporting a portion of bone within a patient having an incomplete bone including providing an adjustable-length implant configured for intramedullary placement and having a first end configured to be coupled to bone and a second end configured to be coupled to bone, wherein the first end and the second end are displaceable relative to each other along a longitudinal axis, placing the adjustable- length implant at least partially within the medullary canal of a bone of a subject, the bone having first and second ends and having at least first and second portions having a space there between, the first portion of the bone including the first end of the bone and the second portion of the bone including the second end of the bone, creating a third portion of the bone by detaching at least some of either the first portion of the bone or the second portion of the bone, wherein the third portion of the bone does not include the first end of the bone or the second end of the bone, coupling an external fixator to the bone, the external fixator having an external base, a first pin and a second pin, by coupling the first
- the transport portion 1 14 and the proximal portion 102 may be coupled to the adjustable-length implant 501 in order to move the transport portion 1 14 with respect to the proximal portion 102 and distal portion 104.
- the proximal portion 102 of the bone 100 may be drilled on an axis through one or more holes 510 in the housing 504 and one or more bone screws 508 may be placed through the one or more holes 510 and secured to the proximal portion 102 of the bone 100.
Landscapes
- Health & Medical Sciences (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Neurology (AREA)
- Surgical Instruments (AREA)
- Prostheses (AREA)
- Transplanting Machines (AREA)
Abstract
Priority Applications (14)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP19219300.1A EP3656323B1 (fr) | 2016-01-28 | 2017-01-30 | Systèmes de transport osseux |
| BR112018015504-7A BR112018015504A2 (pt) | 2016-01-28 | 2017-01-30 | sistemas para transporte ósseo |
| AU2017212806A AU2017212806B2 (en) | 2016-01-28 | 2017-01-30 | Systems for bone transport |
| EP17705517.5A EP3407812B1 (fr) | 2016-01-28 | 2017-01-30 | Systèmes de transport osseux |
| DK17705517.5T DK3407812T3 (da) | 2016-01-28 | 2017-01-30 | System til knogletransport |
| CN201780020777.6A CN108882953B (zh) | 2016-01-28 | 2017-01-30 | 骨搬移用的系统 |
| ES17705517T ES2805657T3 (es) | 2016-01-28 | 2017-01-30 | Sistemas para transporte óseo |
| JP2018539429A JP6888015B2 (ja) | 2016-01-28 | 2017-01-30 | 骨移動のためのシステム |
| CN202110928533.6A CN113598921B (zh) | 2016-01-28 | 2017-01-30 | 骨搬移用的系统 |
| KR1020187024369A KR20180107173A (ko) | 2016-01-28 | 2017-01-30 | 골 이동술용 시스템 |
| US16/046,909 US10918425B2 (en) | 2016-01-28 | 2018-07-26 | System and methods for bone transport |
| US17/136,993 US20210113247A1 (en) | 2016-01-28 | 2020-12-29 | System and methods for bone transport |
| AU2021204968A AU2021204968B2 (en) | 2016-01-28 | 2021-07-12 | Systems for bone transport |
| AU2023206144A AU2023206144B2 (en) | 2016-01-28 | 2023-07-19 | Systems for bone transport |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662288348P | 2016-01-28 | 2016-01-28 | |
| US62/288,348 | 2016-01-28 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| US16/046,909 Continuation US10918425B2 (en) | 2016-01-28 | 2018-07-26 | System and methods for bone transport |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| WO2017132646A1 true WO2017132646A1 (fr) | 2017-08-03 |
Family
ID=58046758
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/US2017/015555 Ceased WO2017132646A1 (fr) | 2016-01-28 | 2017-01-30 | Systèmes de transport osseux |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US10918425B2 (fr) |
| EP (2) | EP3656323B1 (fr) |
| JP (2) | JP6888015B2 (fr) |
| KR (1) | KR20180107173A (fr) |
| CN (2) | CN108882953B (fr) |
| AU (3) | AU2017212806B2 (fr) |
| BR (1) | BR112018015504A2 (fr) |
| DK (1) | DK3407812T3 (fr) |
| ES (2) | ES2805657T3 (fr) |
| WO (1) | WO2017132646A1 (fr) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111150478A (zh) * | 2020-01-02 | 2020-05-15 | 赣南医学院 | 一种生物医用可降解镁合金接骨板 |
| US11065037B2 (en) | 2016-05-19 | 2021-07-20 | Auctus Surgical, Inc. | Spinal curvature modulation systems and methods |
| US20220304730A1 (en) * | 2021-03-26 | 2022-09-29 | Nuvasive Specialized Orthopedics, Inc. | Intramedullary device for ankle fusion |
| WO2023107823A1 (fr) | 2021-12-07 | 2023-06-15 | Nuvasive Specialized Orthopedics, Inc. | Implant réglable à engrenages cycloïdes |
| US12262917B2 (en) | 2016-05-19 | 2025-04-01 | Auctus Surgical, Inc. | Spinal curvature modulation systems and methods |
| US20250221822A1 (en) * | 2024-01-04 | 2025-07-10 | Arthrex, Inc. | Hydraulic taper separator for orthopaedic implant systems and methods of disassembly |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2367486B1 (fr) * | 2008-10-31 | 2024-07-10 | Implantica Patent Ltd. | Dispositif pour l'ajustement des os avec fonction d'ancrage |
| US9179938B2 (en) * | 2013-03-08 | 2015-11-10 | Ellipse Technologies, Inc. | Distraction devices and method of assembling the same |
| DK3407812T3 (da) * | 2016-01-28 | 2020-09-21 | Nuvasive Specialized Orthopedics Inc | System til knogletransport |
| US11278330B2 (en) * | 2017-02-02 | 2022-03-22 | Smith & Nephew, Inc. | Implantable bone adjustment devices |
| PL3491998T3 (pl) | 2017-11-30 | 2021-11-15 | Endotact | Wszczepialne urządzenie do dystrakcji |
| AU2020221828A1 (en) | 2019-02-13 | 2021-10-07 | Children's Hospital Of Philadelphia | Systems and methods for a smart, implantable cranio-maxillo-facial distractor |
| DE102019122354A1 (de) * | 2019-08-20 | 2021-02-25 | Orthofix Srl | Marknagel für eine Distraktion eines Röhrenknochens |
| CN110840624A (zh) * | 2019-12-04 | 2020-02-28 | 北京爱康宜诚医疗器材有限公司 | 骨填充假体 |
| US20210186643A1 (en) * | 2019-12-20 | 2021-06-24 | Endotact | Distraction device with reflector |
| NL2025981B1 (en) * | 2020-07-03 | 2022-03-11 | Osseointegration Int B V | Bone nail device |
| WO2022015898A1 (fr) | 2020-07-17 | 2022-01-20 | Nuvasive Specialized Orthopedics, Inc. | Dispositif et système extramédullaires |
| US12213708B2 (en) * | 2020-09-08 | 2025-02-04 | Nuvasive Specialized Orthopedics, Inc. | Remote control module for adjustable implants |
| CN112263317B (zh) * | 2020-11-16 | 2025-06-06 | 河南科科生物科技有限公司 | 一种新型骨搬移髓内钉 |
| CN112656497B (zh) * | 2020-12-31 | 2024-06-18 | 黄立辉 | 胫骨横向骨搬移装置 |
| US11806054B2 (en) | 2021-02-23 | 2023-11-07 | Nuvasive Specialized Orthopedics, Inc. | Adjustable implant, system and methods |
| EP4153077A1 (fr) * | 2021-06-04 | 2023-03-29 | NuVasive Specialized Orthopedics, Inc. | Implant ajustable à étanchéité et rétention avancées |
| WO2023283326A1 (fr) * | 2021-07-07 | 2023-01-12 | Surgical Design Innovations Ii, Llc | Dispositif de fixation de fracture osseuse et systèmes et procédés associés |
| US20240130764A1 (en) * | 2021-07-07 | 2024-04-25 | Surgical Design Innovations Ii, Llc | Bone fracture fixation device and related systems and methods |
| AU2022325024A1 (en) | 2021-08-03 | 2024-02-22 | Nuvasive Specialized Orthopedics, Inc. | Adjustable implant |
| US20230190342A1 (en) * | 2021-12-17 | 2023-06-22 | Mark Robert BRINKER | Surgical device |
| US11540924B1 (en) * | 2022-02-14 | 2023-01-03 | Ezat EL-SAID | Remotely adjustable orthopedic prostheses |
| US20230338070A1 (en) * | 2022-04-26 | 2023-10-26 | Stryker European Operations Limited | Retrograde Nail with Bone Plate |
| EP4268740A1 (fr) * | 2022-04-26 | 2023-11-01 | Stryker European Operations Limited | Vis plongeante ou de liaison |
| US12551240B2 (en) * | 2022-06-13 | 2026-02-17 | Nuvasive Inc. | Distraction loss magnet on-off mechanism |
| WO2024025719A1 (fr) | 2022-07-26 | 2024-02-01 | Nuvasive Specialized Orthopedics, Inc. | Implant de transport d'os |
| US20240122624A1 (en) * | 2022-10-14 | 2024-04-18 | Globus Medical, Inc. | External fixation system with multi-pin clamp and attachment post |
| US20240225704A9 (en) | 2022-10-21 | 2024-07-11 | Nuvasive Specialized Orthopedics, Inc. | Extramedullary device |
| US12232790B2 (en) | 2022-12-30 | 2025-02-25 | IvyTech Design LLC | Adjustable angle orthopedic distractor, compressor, and distractor-compressor |
| KR102866882B1 (ko) * | 2023-03-15 | 2025-10-17 | 경북대학교 산학협력단 | 뼈 연장술을 위한 신연장치 |
| US12533164B2 (en) | 2023-05-03 | 2026-01-27 | Nuvasive Specialized Orthopedics, Inc. | Adjustable implant |
| AU2024276305A1 (en) * | 2023-05-23 | 2025-12-11 | Vertical Orthopaedics, Inc. | Bone growth device |
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| US8382756B2 (en) | 2008-11-10 | 2013-02-26 | Ellipse Technologies, Inc. | External adjustment device for distraction device |
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| CN111150478A (zh) * | 2020-01-02 | 2020-05-15 | 赣南医学院 | 一种生物医用可降解镁合金接骨板 |
| CN111150478B (zh) * | 2020-01-02 | 2022-04-05 | 赣南医学院 | 一种生物医用可降解镁合金接骨板 |
| US20220304730A1 (en) * | 2021-03-26 | 2022-09-29 | Nuvasive Specialized Orthopedics, Inc. | Intramedullary device for ankle fusion |
| WO2023107823A1 (fr) | 2021-12-07 | 2023-06-15 | Nuvasive Specialized Orthopedics, Inc. | Implant réglable à engrenages cycloïdes |
| US20250221822A1 (en) * | 2024-01-04 | 2025-07-10 | Arthrex, Inc. | Hydraulic taper separator for orthopaedic implant systems and methods of disassembly |
| US12496192B2 (en) * | 2024-01-04 | 2025-12-16 | Arthrex, Inc. | Hydraulic taper separator for orthopaedic implant systems and methods of disassembly |
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| KR20180107173A (ko) | 2018-10-01 |
| JP7101848B2 (ja) | 2022-07-15 |
| US20260013912A1 (en) | 2026-01-15 |
| CN108882953A (zh) | 2018-11-23 |
| BR112018015504A2 (pt) | 2018-12-18 |
| AU2017212806B2 (en) | 2021-04-15 |
| US20210113247A1 (en) | 2021-04-22 |
| JP2021137599A (ja) | 2021-09-16 |
| AU2017212806A1 (en) | 2018-08-09 |
| ES2879405T3 (es) | 2021-11-22 |
| DK3407812T3 (da) | 2020-09-21 |
| US20190015138A1 (en) | 2019-01-17 |
| EP3656323A1 (fr) | 2020-05-27 |
| EP3407812B1 (fr) | 2020-07-01 |
| JP6888015B2 (ja) | 2021-06-16 |
| AU2021204968B2 (en) | 2023-04-20 |
| AU2023206144A1 (en) | 2023-08-10 |
| AU2023206144B2 (en) | 2024-11-14 |
| EP3407812A1 (fr) | 2018-12-05 |
| ES2805657T3 (es) | 2021-02-15 |
| JP2019503801A (ja) | 2019-02-14 |
| CN113598921B (zh) | 2024-08-16 |
| US10918425B2 (en) | 2021-02-16 |
| AU2021204968A1 (en) | 2021-08-05 |
| CN108882953B (zh) | 2021-09-03 |
| CN113598921A (zh) | 2021-11-05 |
| EP3656323B1 (fr) | 2021-06-23 |
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