WO2017155136A1 - Kit d'injection intégré - Google Patents

Kit d'injection intégré Download PDF

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Publication number
WO2017155136A1
WO2017155136A1 PCT/KR2016/002338 KR2016002338W WO2017155136A1 WO 2017155136 A1 WO2017155136 A1 WO 2017155136A1 KR 2016002338 W KR2016002338 W KR 2016002338W WO 2017155136 A1 WO2017155136 A1 WO 2017155136A1
Authority
WO
WIPO (PCT)
Prior art keywords
container
support
solution
needle
cap
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/KR2016/002338
Other languages
English (en)
Korean (ko)
Inventor
이종욱
이민석
강복기
이준우
이선혁
윤우찬
구자홍
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Daewoong Pharmaceutical Co Ltd
Original Assignee
Daewoong Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daewoong Pharmaceutical Co Ltd filed Critical Daewoong Pharmaceutical Co Ltd
Priority to PCT/KR2016/002338 priority Critical patent/WO2017155136A1/fr
Publication of WO2017155136A1 publication Critical patent/WO2017155136A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor

Definitions

  • the present invention relates to an injection kit for injecting a mixture of a drug and an infusion, and more particularly, to an integrated injection kit in which an infusion container and a drug container are integrated.
  • the present invention relates to an integrated injection kit in which a drug and a fluid are mixed only by the rotation of a container support incorporating a drug container.
  • Typical treatment methods include injection or drug administration.
  • a disposable syringe or injector is used, and when a large amount of drug is required or a long-term administration is required, the powder or liquid drug is dissolved in an aqueous solution such as saline to maintain the concentration.
  • the injection method using the fluid is connected to the container containing the dissolved drug and the container containing the fluid using a connecting tool such as a needle or a connecting tube, and the container containing the dissolved drug is inclined so that the dissolved drug inside the fluid is inclined. It is inserted into the container containing the sap and mixed and then injected using a needle connected to the line.
  • a connecting tool such as a needle or a connecting tube
  • This injection method requires a lot of time because the drug container and the fluid container must be connected each time the injection and difficult to operate, there is a problem that the infection is caused by contamination.
  • the protrusion 11 is lowered along the screw groove 18 of the connection port 13, and the fluid contains the fluid.
  • the communication needle 3 fixed to the inlet of the container 2 penetrates the container plug 7 coupled to the inlet of the medicine container 1.
  • the medicine of the medicine container 1 flows into the connection port 13 through the penetrated portion of the container stopper 7, and then the It enters into the flexible container 2 through the opening part 15 formed in the bottom part 16, and mixes with sap.
  • An object of the present invention has been made to solve the conventional problems as described above, the integrated injection which can improve the convenience of operation by integrating the drug container and the fluid container, and minimize the risk of contamination and leakage To provide a kit.
  • the integrated injection kit of the present invention comprises a dissolution solution cap fixed to an inlet of a dissolution solution container containing a dissolution solution;
  • a container support rotatably coupled to the solution cap and close to the solution container upon rotation, and having a medicine container containing a drug therein; And when the container support is rotated in a direction approaching the solution container, the upper and lower needles penetrate the chemical container and the solution cap respectively by the pressing force transmitted from the container support. It includes; a communication member for communicating the two containers.
  • the communication member includes a penetrating needle penetrating the inlet and the solution cap of the chemical container to the upper and lower ends, respectively, and having a communication hole penetrated in the vertical direction.
  • the communication member When the vessel support is rotated in the direction of approaching the solution container, the communication member causes the top and the bottom of the penetrating needle to penetrate the inlet of the chemical container and the solution cap simultaneously or sequentially while being pressed downward by the container support. Is done.
  • the solution cap includes: a container joint portion joined to an inlet of the solution container; A support coupling portion extending from the container coupling portion and having a container support screwed thereto; A partition portion formed between the vessel junction portion and the support coupling portion to partition an inner space of the vessel junction portion and the support coupling portion; A needle inserting portion protruding from the center of the partition portion into the inner space of the container junction portion and into which the lower needle of the communication member is inserted; And a sealing part formed inside the needle insertion part to seal the dissolution liquid of the dissolution liquid container from leaking to the outside and penetrate by the lower needle of the communication member during use.
  • the container support includes a support body in which a chemical container is embedded, and a lower end of which is screwed to the support coupling portion of the solution cap; And a container support part protruding from the center of the bottom of the support body into the support body to support the medicine container and having a through hole formed in the vertical direction.
  • the communication member includes a penetrating needle; And a lift coupling part integrally formed with the penetrating needle and configured to be lifted and coupled to the bottom of the support body constituting the container support.
  • the drug container and the solution container is integrally provided, and the operation is convenient because the drug and the fluid can be mixed only by the operation of rotating the container support during use.
  • FIG. 1 is a view of an infusion container according to the prior art
  • FIG. 2 is a perspective view of an integrated injection kit according to a preferred embodiment of the present invention.
  • FIG. 3 is a cross-sectional view taken along the line A-A of FIG.
  • FIG. 5 is a cross-sectional view of the container support.
  • FIG. 6 is a sectional view of a communication member.
  • FIG. 7 to 9 are views showing the use of the integrated injection kit according to a preferred embodiment of the present invention.
  • FIG. 2 is a perspective view of the integrated injection kit according to a preferred embodiment of the present invention
  • Figure 3 is a cross-sectional view taken along line A-A of FIG.
  • Integral injection kit according to an embodiment of the present invention, the solution container 100, the drug container 200, the solution cap 300, the container support 400 and the communication member 500.
  • the dissolution solution container 100 is accommodated therein the sap solution, the solution solution container 100 is made of a flexible container to be pressed during the use process, but is not limited thereto.
  • the medicine container 200 contains a powder or a liquid medicine therein, and the rubber field 210 is forcibly fitted to the inlet for sealing.
  • the solution cap 300 is joined to the inlet of the solution container 100, and when the mixing of the fluid and the drug is not necessary, the solution cap 100 is sealed, and when the solution of the fluid and the drug is needed, the communication member ( By 500) the state of sealing is forcibly released.
  • the container support 400 has a medicine container 200 therein.
  • the vessel support 400 is screwed so as to be movable in position to the solution cap 300. That is, by the helical coupling structure, when the container support 400 is rotated in a predetermined direction, the container support 400 is moved in a direction approaching the solution cap 300 or away from the solution cap 300.
  • the container support 400 pushes the communication member 500 toward the solution container 100 in the process of moving toward the solution container 100.
  • the communication member 500 is positioned between the solution cap 300 and the container support 400, and is pushed by the container support 400 while rotating the container support 400 toward the solution container 100.
  • the needle and the needle of the lower penetrates the rubber field 210 and the solution cap 300 of the drug container 200, respectively, so that the drug container 200 and the solution container 100 in fluid communication with each other . That is, through the communication member 500, the substance in the chemical container 200 and the solution container 100 is movable.
  • the solution cap 300 includes a container joint 310, a support coupling part 320, a partition 330, and a needle insertion part 340.
  • the container junction part 310 is formed in the shape of a hollow tube and is joined by a thermal bonding method in the state inserted into the inlet of the solution container 100. The upper end of the vessel junction 310 is exposed to the outside of the solution container 100.
  • the support coupling part 320 is formed in a hollow tube shape and extends integrally from an upper end of the container bonding part 310 to be positioned outside the dissolution solution container 100, and the container support 400 is screwed to move in position. do.
  • An inner circumferential surface of the support coupling part 320 is provided with a screw part to which the container support 400 is screwed.
  • the lower end of the container support 400 is detachably inserted into the inner space of the support coupling part 320.
  • a separation prevention jaw 321 is formed at an outer upper end of the support coupling part 320 to prevent separation of the container support 400.
  • the partition portion 330 is formed between the container junction portion 310 and the support coupling portion 320 and partitions a space formed inside the container junction portion 310 and a space formed inside the support coupling portion 320.
  • the needle inserting portion 340 is a place where the lower needle of the communication member 500 is inserted, and protrudes into the inner space of the container junction portion 310 at the center of the partition portion 330. Inside the needle inserting portion 340, a sealing portion 350 is formed to seal the solution of the solution liquid container 100 so as not to leak through the needle inserting portion 340. In use, the seal 350 is penetrated by the lower needle of the communication member 500.
  • the solution cap 300 is bonded to the solution container 100 by a thermal bonding method or the like, and when not in use (when mixing of the drug and the fluid is not required), the partition 330 and the seal 350 are disposed. As a result, the sap of the solution container 100 does not leak out.
  • the sealing portion 350 is penetrated by the lower saliva of the communication member 500, so the sap of the solution container 100 to the outside through the saliva insert 340 Not only can it leak out, but a powder or a liquid medicine can also flow into the solution container 100 from the outside.
  • FIG. 5 is a cross-sectional view of the container support.
  • the container support 400 includes a support body 410, a coupling part 420, a container support part 430, and a support cap 440.
  • the support body 410 is formed in the form of a hollow tube, the medicine container 200 is embedded therein.
  • the upper and lower ends of the support body 410 are both open, and a flange portion 411 is formed at the upper end of the support body 410 to be tightly fixed to the support cap 440.
  • the coupling part 420 is formed in the shape of a hollow tube and is formed in the shape of the outer coupling part 421 and a hollow tube shape so as to be lifted and coupled outside the support coupling part 320 of the solution cap 300.
  • the inner coupling portion 422 is screwed so as to be movable in the position inside the support coupling portion (320).
  • the outer coupling part 421 and the inner coupling part 422 extend integrally from the lower end of the support body 410, and the inner coupling part 422 having a smaller diameter is spaced apart from each other in the large outer coupling part 421. It is inserted.
  • the inner lower end of the outer coupling portion 421 is caught by the separation prevention jaw 321 of the support coupling portion 320 constituting the solution cap 300 to prevent the container support 400 from being separated from the solution cap 300.
  • the locking protrusion 423 is formed to protrude inward. Due to the separation prevention jaw 321 and the locking protrusion 423, the user can separate the container support 400 from the solution cap 300 only by pulling the container support 400 above a predetermined force.
  • a screw portion for screwing the support coupling portion 320 is formed on the outer circumferential surface of the inner coupling portion 422.
  • the container support part 430 is integrally formed from the lower end of the inner side coupling part 422 and shields the lower end of the space in which the chemical
  • the bottom surface 431 is formed with a coupling hole 433 which is coupled to some of the components of the communication member 500 to penetrate up and down, the container support 432 is the upper needle of the communication member 500 penetrates up and down
  • the needle through-hole 434 is formed therein so that it can be.
  • the support cap 440 is inserted into the open upper end of the support body 410 and inserts the chemical container 200 into the support body 410, so that the chemical container 200 does not escape from the support body 410. 410 shields the top.
  • the edge of the support cap 440 is in close contact with the upper flange portion 411 of the support body 410, the lower portion of the support cap 440 is forcibly fitted into the upper end of the support body 410.
  • the container support 400 having the configuration as described above is moved to the dissolution liquid container 100 on the dissolution liquid cap 300 by the rotation, and moves the chemical container 200 toward the dissolution liquid container 100,
  • the communication member 500 is pushed toward the solution container 100 to pressurize it.
  • the drug container 200 is embedded in the container support 400 so that the inlet is directed downward.
  • the rubber field 210 of the drug container 200 in the container support 400 is seated while being in close contact with the upper end of the container support 432 constituting the container support 430. Therefore, even when the rubber field 210 is penetrated by the upper needle of the communication member 500, the medicine of the medicine container 200 flows only inside the container support 432 but does not leak to the outside of the container support 432. .
  • FIG. 6 is a cross-sectional view of the communication member.
  • the communication member 500 includes a penetrating needle 510 and a lift coupling part 520.
  • the penetrating needle 510 is a hollow communication hole 511 is formed so that the drug or sap flow therein and the top and bottom are formed to be inclined in an oblique direction to the rubber field 210 and the solution cap of the drug container 200 It can easily penetrate the sealing portion 350 of (300).
  • Lift coupling portion 520 is integrally formed on the outer side of the penetrating needle 510 is coupled to the lower end of the container support (400).
  • the elevating coupling part 520 extends orthogonally from the outside of the penetrating needle 510 to contact the bottom surface of the bottom surface 431 of the container support part 430 of the container support 400.
  • a coupling piece 522 formed to protrude upwardly from an upper surface of the bottom contact surface 521 to penetrate the coupling hole 433 of the container supporter 430 to be elevated.
  • On the upper end of the coupling piece 522 is formed a locking projection 523 is caught on the upper surface of the bottom surface 431 constituting the container support 430 so as not to be separated from the container support 400 when the coupling piece 522 is lowered do.
  • the communication member 500 having the configuration described above, when the container support 400 is rotated toward the solution solution container 100, the communication member 500 is pushed toward the solution solution container 100 by the container support 400, thereby The upper and lower ends of the container support 432 and the needle inserting portion 340 of the solution cap 300 are respectively penetrated through the rubber field 210 and the sealing unit 350 respectively. .
  • FIG. 7 to 9 are views showing the use of the integrated injection kit according to a preferred embodiment of the present invention.
  • the container support 400 and the drug container 200 are located at a distance from the solution container 100 so that the drug and the fluid do not mix with each other.
  • the sap contained in the dissolution liquid container 100 is sealed by the sealing portion 350 of the dissolution liquid cap 300, the liquid is not leaked to the outside of the dissolution liquid container 100, and thus the liquid solution 200 is stored in the chemical container 200. Since the contained drug is sealed by the rubber field 210, it does not leak out of the drug container 200.
  • the container support 400 When the drug and the fluid are to be mixed for injection, the container support 400 is rotated in one direction as shown in FIG. 7 to move the container solution toward the solution container 100. In this process, the chemical
  • the bottom contact surface 521 of the communication member 500 contacts the bottom surface 431 of the container support 400.
  • the communication member 500 is pressed by the vessel support 400 while being moved toward the solution container 100 together with the vessel support 400.
  • the lower end of the penetrating needle 510 of the communication member 500 is inserted into the needle inserting portion 340 of the solution cap 300 to pass through the sealing portion 350.
  • the drug container 200 and the solution container 100 communicate with each other through a communication hole 511 formed in the penetrating needle 510, whereby the drug of the drug container 200 is dissolved in the solution.
  • the drug is introduced into the container 100 and the sap is mixed with each other.
  • the rubber field 210 of the drug container 200 is in close contact with the top of the container support 432 is inserted into the upper end of the penetrating needle 510, the bottom contact surface of the communication member 500 521 is in close contact with the compartment 330 of the solution cap 300, so that the drug and the sap does not leak out of the communication hole 511 of the penetrating needle 510.
  • the rubber field 210 of the chemical container 200 is first penetrated by the communication member 500 and the sealing portion 350 of the solution cap 300 is later penetrated.
  • the sealing part 350 may be penetrated first, and the rubber sheet 210 may be penetrated later. This may vary depending on the stiffness difference between the rubber field 210 and the sealing unit 350 or the length difference between the upper and lower ends of the penetrating needle 510 constituting the communication member 500.

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

La présente invention concerne un kit d'injection pour mélanger un médicament et un fluide médical et les injecter et, plus spécifiquement, un kit d'injection intégré pour intégrer un contenant de fluide médical et un contenant de médicament. En particulier, la présente invention concerne un kit d'injection intégré dans lequel un médicament et un fluide médical sont mélangés seulement par la rotation d'un support de contenant dans lequel un contenant de médicament est incorporé. Le kit d'injection intégré de la présente invention comprend : un capuchon de solution fixé à l'ouverture d'un contenant de solution dans lequel une solution est contenue; un support de contenant couplé de manière rotative au capuchon de solution de façon à s'approcher du contenant de solution pendant la rotation, et ayant un contenant de médicament, dans lequel un médicament est contenu, incorporé dans ce dernier; et un élément de communication situé entre le capuchon de solution et le support de contenant, et permettant à une aiguille supérieure et une aiguille inférieure de pénétrer respectivement dans le contenant de médicament et le capuchon de solution au moyen de la pression transférée depuis le support de contenant lorsque le support de contenant est tourné dans la direction s'approchant du contenant de solution, de telle sorte que les deux contenants communiquent l'un avec l'autre.
PCT/KR2016/002338 2016-03-09 2016-03-09 Kit d'injection intégré Ceased WO2017155136A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/KR2016/002338 WO2017155136A1 (fr) 2016-03-09 2016-03-09 Kit d'injection intégré

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/KR2016/002338 WO2017155136A1 (fr) 2016-03-09 2016-03-09 Kit d'injection intégré

Publications (1)

Publication Number Publication Date
WO2017155136A1 true WO2017155136A1 (fr) 2017-09-14

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2016/002338 Ceased WO2017155136A1 (fr) 2016-03-09 2016-03-09 Kit d'injection intégré

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WO (1) WO2017155136A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4570376A1 (fr) * 2023-12-13 2025-06-18 Jeol Ltd. Dispositif d'alimentation en liquide

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07275324A (ja) * 1994-04-12 1995-10-24 Fujisawa Pharmaceut Co Ltd 輸液用容器及びその溶解液容器の製造方法
KR0134789B1 (ko) * 1991-08-06 1998-04-14 게로프 호먼 의약품 주사기와 주사방법
KR100360586B1 (ko) * 1993-09-07 2003-05-12 데비오테크 에스.에이. 2종의화합물을혼합하는주사장치
KR20070115878A (ko) * 2005-02-09 2007-12-06 가켄 세야쿠 가부시키가이샤 시린지 장치 및 그 장치를 이용한 물약의 조제 방법
KR20120122623A (ko) * 2011-04-29 2012-11-07 대한약품공업 주식회사 키트 조립형 수액 포트 및 약물 오용 방지용 수액백
KR20160029168A (ko) * 2014-09-04 2016-03-15 주식회사 대웅제약 일체형 주사 키트

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR0134789B1 (ko) * 1991-08-06 1998-04-14 게로프 호먼 의약품 주사기와 주사방법
KR100360586B1 (ko) * 1993-09-07 2003-05-12 데비오테크 에스.에이. 2종의화합물을혼합하는주사장치
JPH07275324A (ja) * 1994-04-12 1995-10-24 Fujisawa Pharmaceut Co Ltd 輸液用容器及びその溶解液容器の製造方法
KR20070115878A (ko) * 2005-02-09 2007-12-06 가켄 세야쿠 가부시키가이샤 시린지 장치 및 그 장치를 이용한 물약의 조제 방법
KR20120122623A (ko) * 2011-04-29 2012-11-07 대한약품공업 주식회사 키트 조립형 수액 포트 및 약물 오용 방지용 수액백
KR20160029168A (ko) * 2014-09-04 2016-03-15 주식회사 대웅제약 일체형 주사 키트

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4570376A1 (fr) * 2023-12-13 2025-06-18 Jeol Ltd. Dispositif d'alimentation en liquide

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