WO2018068773A2 - Composition bactéricide contenant de la benzisothiazolinone et une protéine activatrice d'alternaria tenuissima - Google Patents

Composition bactéricide contenant de la benzisothiazolinone et une protéine activatrice d'alternaria tenuissima Download PDF

Info

Publication number
WO2018068773A2
WO2018068773A2 PCT/CN2017/115359 CN2017115359W WO2018068773A2 WO 2018068773 A2 WO2018068773 A2 WO 2018068773A2 CN 2017115359 W CN2017115359 W CN 2017115359W WO 2018068773 A2 WO2018068773 A2 WO 2018068773A2
Authority
WO
WIPO (PCT)
Prior art keywords
composition
bactericidal composition
active component
alternaria alternata
composition according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/CN2017/115359
Other languages
English (en)
Chinese (zh)
Other versions
WO2018068773A3 (fr
Inventor
季红进
仲汉根
花伟
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Jiangsu Huifeng Bio Agriculture Co Ltd
Original Assignee
Jiangsu Huifeng Bio Agriculture Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jiangsu Huifeng Bio Agriculture Co Ltd filed Critical Jiangsu Huifeng Bio Agriculture Co Ltd
Publication of WO2018068773A2 publication Critical patent/WO2018068773A2/fr
Publication of WO2018068773A3 publication Critical patent/WO2018068773A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/30—Microbial fungi; Substances produced thereby or obtained therefrom
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/80—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2

Definitions

  • the invention belongs to the field of agricultural plant protection, in particular to a germicidal composition with improved properties, in particular to a germicidal composition comprising benzisothiazolinones and very fine chain spore activation proteins.
  • Benzoisothiazolinones are a new type of broad-spectrum fungicide mainly used for the prevention and treatment of various bacterial and fungal diseases such as cereal crops, vegetables and fruits.
  • the mechanism of bactericidal action mainly includes destroying the nuclear structure of the pathogen, causing it to lose the heart part and failing to death and interfering with the metabolism of the pathogenic cells, causing its physiological disorder and ultimately leading to death. It can effectively protect plants from pathogens in the early stage of disease occurrence. Increasing the dosage after disease occurrence can obviously control the spread of pathogens, thus achieving the dual functions of protection and eradication.
  • Plant activator protein is a new type of protein that is screened, isolated and purified from Alternaria alternata, which activates the plant's own immune system by activating the molecular immune system in plants; A series of metabolic regulation, promote plant roots, stems, leaves growth and increase chlorophyll content, increase crop yield, and have high control effect on a variety of plant diseases.
  • the object of the present invention is to solve the resistance of the bactericide in practical application and the problem of soil residue, and to screen out the fungicides with different sterilization principles to obtain a new fungicide composition, so as to improve the control effect of the bactericide and delay the resistance.
  • Sexual production reducing the amount of application, reducing the cost of prevention.
  • Another object of the present invention is to provide a use of a bactericidal composition comprising two active ingredients A and B for controlling crop diseases in the agricultural field.
  • the object of the invention can be achieved by the following measures:
  • a synergistic fungicidal composition comprising two active components A and B, wherein active component A is a structural compound having formula (I), and active component B is Alternaria alternata Activate the protein.
  • R is selected from H or a C 1 - C 8 alkyl group.
  • the C 1 -C 8 alkyl group in the present invention means a linear or branched alkyl group having 1 to 8 carbon atoms, and includes a C 1 alkyl group (e.g., methyl group) and a C 2 alkyl group (e.g., ethyl group). , C 3 alkyl (such as n-propyl, isopropyl), C 4 alkyl (such as n-butyl, isobutyl, tert-butyl, sec-butyl), C 5 alkyl (such as n-pentyl, etc.) , C 6 alkyl, C 7 alkyl, C 8 alkyl. It includes, but is not limited to, C 1 -C 6 alkyl, C 1 -C 5 alkyl, C 1 -C 4 alkyl, and the like.
  • R is selected from H or a C 1 -C 4 alkyl group.
  • R is selected from the group consisting of H, -CH 3 or -C 4 H 9 .
  • A is 1,2-benzisothiazolin-3-one (abbreviated as BIT in the specification).
  • R is CH 3
  • A is 2-methyl-1,2-benzisothiazolin-3-one (abbreviated as MBIT in the specification).
  • R is C 4 H 9
  • A is 2-butyl-1,2-benzisothiazolin-3-one
  • the "butyl group” in the formula is preferably n-butyl (instruction Referred to as BBIT).
  • the inventors have found through experiments that the composition of the present invention is used for controlling bacterial or fungal diseases of crops, and the control effect is obvious, and more importantly, the application amount is reduced, and the use cost is lowered.
  • the compounds containing component A and component B have different structural types and different mechanisms of action. The combination of the two can expand the bactericidal spectrum, and can delay the generation and development of pathogen resistance to a certain extent, and component A and group There is no cross-resistance between points B.
  • the weight ratio between the two components in the bactericidal composition of the present invention is from 30 to 1:1 to 30.
  • the weight ratio between the components of component A and component B can be further optimized to 20 to 1:1 to 20.
  • the weight ratio between the two components of A and B can be arbitrarily adjusted within the range of the following ratios: 30:1, 29:1, 28:1, 27:1, 26:1. 25:1, 24:1, 23:1, 22:1, 21:1, 20:1, 19:1, 18:1, 17:1, 16:1, 15:1, 14:1, 13 : 1, 12: 1, 11: 1, 10: 1, 9: 1, 8: 1, 7: 1, 6: 1, 5: 1, 4: 1, 3: 1, 2: 1, 1:1 , 1:2, 1:3, 1:4, 1:5, 1:6, 1:7, 1:8, 1:9, 1:10, 1:11, 1:12, 1:13, 1 :14, 1:15, 1:16, 1:17, 1:18, 1:19, 1:20, 1:21, 1:22, 1:23, 1:24, 1:25, 1:26 1,27, 1:28, 1:29, 1:30, can also be selected within the range of any two ratios above, these ratios can be understood as weight to volume ratio, or mass ratio, can also Including the molar ratio.
  • composition of the present invention can be made into a pesticide-acceptable dosage form from the active ingredient and agrochemical adjuvant or adjuvant. Further, the composition is made into a pesticide-acceptable dosage form from 2 to 80% by weight of the active ingredient and 98 to 20% by weight of the pesticide adjuvant or adjuvant.
  • the present invention provides the use of a bactericidal composition comprising component A and component B for controlling crop diseases in the agricultural sector, in particular for controlling fungal or bacterial diseases of certain crops.
  • composition may specifically comprise an agrochemical adjuvant or an auxiliary such as one or more of a carrier, a solvent, a dispersing agent, a wetting agent, an adhesive, a thickener, a binder, a surfactant or a fertilizer.
  • auxiliary such as one or more of a carrier, a solvent, a dispersing agent, a wetting agent, an adhesive, a thickener, a binder, a surfactant or a fertilizer.
  • auxiliary such as one or more of a carrier, a solvent, a dispersing agent, a wetting agent, an adhesive, a thickener, a binder, a surfactant or a fertilizer.
  • auxiliary such as one or more of a carrier, a solvent, a dispersing agent, a wetting agent, an adhesive, a thickener, a binder, a surfactant or a fertilizer.
  • Common auxiliaries can be mixed during the application.
  • auxiliaries or auxiliaries may be solid or liquid, they are usually materials commonly used in the processing of dosage forms, such as natural or regenerated minerals, solvents, dispersants, wetting agents, adhesives, thickeners, binders. .
  • the method of application of the compositions of the invention comprises the use of the compositions of the invention for aerial parts of plants, in particular leaves or foliage. You can choose to soak or apply to the surface of the control object.
  • the frequency of administration and the amount administered will depend on the biological and climatic conditions of the pathogen.
  • the plant growth site such as rice fields, may be wetted with a liquid formulation of the composition, or the composition may be applied to the soil in solid form, such as in the form of granules (soil application), the composition may be passed from the soil to the plant through the roots of the plant. In vivo (systemic action).
  • composition of the present invention can be prepared into various pesticide-acceptable dosage forms including, but not limited to, emulsifiable concentrates, suspending agents, wettable powders, water-dispersible granules, powders, granules, aqueous preparations, aqueous emulsions, microemulsions, poison baits.
  • the dosage form of the invention employs a wettable powder, a suspending agent, a water-dispersible granule, an aqueous emulsion or a microemulsion.
  • the compositions may be applied by spraying, misting, dusting, spreading or pouring, and the like.
  • composition of the present invention can be prepared into various dosage forms by a known method, and the active ingredient and the auxiliary agent, such as a solvent, a solid carrier, and, if necessary, can be uniformly mixed and ground together with the surfactant to prepare a desired preparation. Dosage form.
  • the above solvent may be selected from aromatic hydrocarbons, preferably containing from 8 to 12 carbon atoms, such as a mixture of xylenes or substituted benzenes, phthalates such as dibutyl phthalate or dicaprylic acid, aliphatic hydrocarbons such as rings.
  • aromatic hydrocarbons preferably containing from 8 to 12 carbon atoms, such as a mixture of xylenes or substituted benzenes, phthalates such as dibutyl phthalate or dicaprylic acid, aliphatic hydrocarbons such as rings.
  • Alkenes or paraffins, alcohols and glycols and their ethers and esters such as ethanol, ethylene glycol, ethylene glycol monomethyl
  • ketones such as cyclohexanone
  • highly polar solvents such as N-methyl-2 Pyrrolidone, dimethyl sulfoxide or dimethylformamide
  • vegetable or vegetable oils such as soybean oil.
  • the above solid carriers are typically natural mineral fillers such as talc, kaolin, montmorillonite or activated clay.
  • a highly dispersible silicic acid or a highly dispersible adsorbent polymer carrier such as a particulate adsorbent carrier or a non-adsorbing carrier, and a suitable particulate adsorbent carrier is porous, such as pumice, bentonite or Bentonite; a suitable non-adsorbing carrier such as calcite or sand.
  • a large amount of pre-granulated materials of inorganic or organic nature can be used as a carrier, in particular dolomite.
  • Suitable surfactants are lignosulfonic acid, naphthalenesulfonic acid, phenolsulfonic acid, alkaline earth metal or amine salts, alkylarylsulfonates, alkyl groups Sulfates, alkyl sulfonates, fatty alcohol sulphates, fatty acids and sulfated fatty alcohol glycol ethers, as well as condensates of sulfonated naphthalene and naphthalene derivatives with formaldehyde, naphthalene or naphthalene sulfonic acid with phenol and formaldehyde Condensate, polyoxyethylene octyl phenyl ether, ethoxylated isooctyl phenol, octyl phenol, nonyl phenol, alkyl aryl polyglycol ether, tributyl benzene poly
  • the active ingredient A can be first dissolved in certain specific basic substances to form a benzisothiazolin metal salt.
  • suitable basic substances include: alkali metal carbonates, alkali metal hydrogens Oxide (such as sodium hydroxide, potassium hydroxide), alkali metal alkoxy carbonate, alkali metal alkoxide or magnesium methoxide.
  • the two active ingredients in the compositions of the present invention exhibit synergistic effects, the activity of which is more pronounced than the expected sum of activity using a single compound, and the individual activity of a single compound.
  • the synergistic effect is manifested by allowing for a reduced application rate, a broader fungicidal control profile, quicker effect, longer lasting control effect, better control of plant harmful fungi by only one or a few applications, and broadening of possible application. Intervals. These properties are particularly desirable in the practice of plant fungi control.
  • the fungicide composition of the invention can be applied to the field of agricultural diseases for controlling crop diseases, and the specific diseases targeted include, but not limited to, wheat diseases (such as wheat scab, wheat powdery mildew, wheat rust, etc.) and rice diseases (such as: Rice sheath blight, rice blast disease, rice blast, rice bacterial streaks, etc., corn diseases (such as: corn smut, corn big spot, corn spot), cucumber diseases (such as: cucumber frost Mold disease, cucumber powdery mildew, cucumber anthracnose, cucumber bacterial angular spot disease, etc., tomato diseases (such as: tomato anthracnose, tomato gray mold, tomato bacterial angular spot disease, etc.), grape diseases (such as: grape frost Mildew, grape gray mold, grape powdery mildew), apple disease (such as apple ring disease, apple anthracnose, etc.), citrus disease (citrus canker disease, citrus canker, citrus anthracnose), tobacco disease (tobacco wildfire disease) )Wait.
  • the other characteristics exhibited by the bactericidal composition of the present invention are mainly as follows: 1.
  • the compounding of the composition of the present invention has obvious synergistic effect; 2. Since the chemical composition of the two single agents of the present composition is greatly different, the effect The mechanism is completely different, there is no cross-resistance, and the problem of resistance caused by the separate use of the two single agents can be delayed; 3.
  • the composition of the present invention is safe and safe for crops. It has been proved by experiments that the bactericidal composition of the invention has stable chemical properties, remarkable synergistic effect, and exhibits obvious synergistic effect and complementary effect on the control object.
  • the active ingredient active group A and the active component B, and the auxiliary agent and the filler are uniformly mixed according to the formula, and are pulverized into a wettable powder by a jet stream, and then added with a certain amount of water to be mixed and extruded, granulated, and dried and sieved.
  • a water dispersible granule product A water dispersible granule product.
  • Example 1 31% BIT ⁇ Algae spore-acting protein water-dispersible granules
  • Example 2 31.5% BIT ⁇ Algae spore-acting protein water-dispersible granules
  • Example 3 31% MBIT ⁇ Algae spore-acting protein water-dispersible granules
  • Example 4 31.5% MBIT ⁇ Algae spore-acting protein water-dispersible granules
  • Example 5 31BBIT ⁇ Alternaria alternata activator protein water dispersible granules
  • Example 6 31.5% BBIT ⁇ Algae spore-acting protein water-dispersible granules
  • the active ingredient active group A and the active component B, and the components such as a dispersing agent, a wetting agent, a thickener and water are uniformly mixed according to the formula, and after being sanded and/or sheared at a high speed, a semi-finished product is obtained. After the analysis, the water is mixed and evenly filtered to obtain the finished product.
  • Example 7 10.5% BIT ⁇ Alternaria alternata activator suspension
  • BIT 10% very fine chain spore activation protein 0.5%, sodium alkylbenzene sulfonate 4%, methyl cellulose 2%, propylene glycol 2%, silicone oil 0.02%, water to 100%.
  • Example 8 5% BIT ⁇ Alternaria alternata activator suspension
  • Example 9 33% BIT ⁇ Alternaria alternata activator suspension
  • Example 11 5% MBIT ⁇ Alternaria alternata activator suspension
  • Example 12 33% MBIT ⁇ Alternaria alternata activator suspension
  • Example 14 5% BBIT ⁇ Alternaria alternata activator suspension
  • the active ingredient A and the B active ingredient are sufficiently mixed with various auxiliary agents and fillers, and are pulverized by an ultrafine pulverizer to obtain a wettable powder.
  • Example 16 3.3% BIT ⁇ Algae spore-acting protein wettable powder
  • BIT 3% Alternaria algae activator protein 0.3%, polyoxyethylene tristyrene phenyl phosphate 2%, sodium lignin naphthalene sulfonate 2%, molecular sieve 2%, kaolin to 100%.
  • Example 17 30% BIT ⁇ Alternaria alternata activator wettable powder
  • Example 18 3.3% MBIT ⁇ Algae spore-acting protein wettable powder
  • MBIT was 3%
  • Alternaria algae activator protein was 0.3%
  • the remaining fractions were prepared according to the method of Example 16.
  • Example 19 31% MBIT ⁇ Alternaria alternata activator wettable powder
  • Example 20 3.3% BBIT ⁇ Algae spore-acting protein wettable powder
  • Example 21 31% BBIT ⁇ Algae spore-acting protein wettable powder
  • the control effect is converted into the probability value (y)
  • the concentration of the drug solution ( ⁇ g/ml) is converted into the logarithm value (x)
  • the virulence equation is calculated by the least squares method and the concentration EC50 is suppressed
  • the virulence index of the drug is calculated according to the method of Sun Yunpei.
  • the co-toxicity coefficient (CTC) is calculated according to the method of Sun Yunpei.
  • Measured virulence index (ATI) (standard drug EC50 / test drug EC50) * 100
  • Theoretical virulence index (TTI) A virulence index * Percentage of A in the mixture + B virulence index * Percentage of B in the mixture
  • CTC Co-toxicity coefficient [mixture measured virulence index (ATI) / mixed theory virulence index (TTI)] * 100
  • CTC ⁇ 80 the composition showed antagonism, 80 ⁇ CTC ⁇ 120, the composition showed an additive effect, CTC ⁇ 120, and the composition showed synergistic effect.
  • Test method In the early stage of the disease, the first spray was immediately performed, and after 7 days, the second application was carried out, each treatment of 4 cells, 20 square meters per cell. The incidence of the disease was investigated before the drug and 11 days after the second drug. Each plot was randomly sampled at 5 points, and 5 crops were investigated at each point. The percentage of the lesion area per leaf on the whole plant was counted and graded. Disease index and control effect.
  • Grade 1 less than 5 leaf lesions, less than 1 cm in length;
  • Grade 3 6-10 leaf lesions, some lesions are longer than 1 cm;
  • Grade 5 11-25 leaf lesions, some lesions are connected into pieces, and the lesion area accounts for 10-25% of the leaf area;
  • Grade 7 more than 26 leaf lesions, the lesions are connected into pieces, and the lesion area accounts for 26-50% of the leaf area;
  • Grade 9 The lesions are connected into pieces, and the area of the lesions accounts for more than 50% of the leaf area or the whole leaves are dead.

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Environmental Sciences (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne une composition bactéricide. Ladite composition comprend deux principes actifs A et B, le principe actif A étant un composé présentant une structure répondant à la formule (I), le principe actif B étant une protéine activatrice d'Alternaria tenuissima, le rapport en poids des deux constituants étant 20-1/1-20. L'invention concerne également un procédé de préparation de la composition et une utilisation de la composition. Les résultats des essais montrent que la composition bactéricide de la présente invention se caractérise par une synergie significative et, qui plus est, par des quantités d'application réduites et des coûts d'utilisation réduits. La présente composition bactéricide assure une prévention et un traitement efficaces contre certaines bactéries ou maladies fongiques des cultures. La combinaison de bactéricides ayant des mécanismes et des modes d'action différents permet d'élargir le spectre bactéricide, de retarder la résistance fongique et bactérienne, et d'améliorer l'effet de prévention et de traitement.
PCT/CN2017/115359 2016-10-11 2017-12-09 Composition bactéricide contenant de la benzisothiazolinone et une protéine activatrice d'alternaria tenuissima Ceased WO2018068773A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201610889263.1 2016-10-11
CN201610889263.1A CN106561720B (zh) 2016-10-11 2016-10-11 含苯并异噻唑啉酮类和极细链格孢激活蛋白的杀菌组合物

Publications (2)

Publication Number Publication Date
WO2018068773A2 true WO2018068773A2 (fr) 2018-04-19
WO2018068773A3 WO2018068773A3 (fr) 2018-05-31

Family

ID=58531818

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2017/115359 Ceased WO2018068773A2 (fr) 2016-10-11 2017-12-09 Composition bactéricide contenant de la benzisothiazolinone et une protéine activatrice d'alternaria tenuissima

Country Status (2)

Country Link
CN (1) CN106561720B (fr)
WO (1) WO2018068773A2 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106561720B (zh) * 2016-10-11 2019-04-16 江苏辉丰农化股份有限公司 含苯并异噻唑啉酮类和极细链格孢激活蛋白的杀菌组合物
CN108338173A (zh) * 2017-08-08 2018-07-31 江苏辉丰农化股份有限公司 一种包含苯并异噻唑啉酮类和氟噻唑吡乙酮的杀菌组合物
CN115918656B (zh) * 2022-10-13 2024-08-02 顺毅股份有限公司 一种含有生物提取物的杀菌组合物

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101669486B (zh) * 2009-10-16 2012-06-06 深圳诺普信农化股份有限公司 一种含苯醚菌酯的杀菌组合物
CN101984809B (zh) * 2010-07-22 2012-11-21 福建诺德生物科技有限责任公司 一种以松脂基植物油为载体的油悬制剂及其制备方法
CN102405938B (zh) * 2011-09-21 2012-09-05 浙江龙游东方阿纳萨克作物科技有限公司 极细链格孢激活蛋白-井冈霉素可湿性粉剂及应用
CN103828828B (zh) * 2012-11-27 2015-02-18 陕西汤普森生物科技有限公司 一种含极细链格孢激活蛋白的植物生长调节组合物
CN103843826A (zh) * 2012-12-04 2014-06-11 陕西汤普森生物科技有限公司 一种含极细链格孢激活蛋白的杀菌组合物
CN105767013B (zh) * 2012-12-04 2018-09-11 陕西汤普森生物科技有限公司 一种含极细链格孢激活蛋白的杀菌组合物
CN104336081A (zh) * 2013-08-09 2015-02-11 陕西美邦农药有限公司 一种含噻唑锌的高效杀菌增产组合物
CN103704234B (zh) * 2014-01-07 2015-04-01 中国农业科学院植物保护研究所 一种防治农业细菌性病害的组合物
CN104798789B (zh) * 2014-01-28 2018-11-27 中国科学院大连化学物理研究所 一种广谱性寡糖复配杀菌剂及其应用
CN104012579B (zh) * 2014-06-23 2017-01-04 联保作物科技有限公司 一种杀菌组合物及其应用
CN105875651A (zh) * 2014-10-17 2016-08-24 中国农科院植保所廊坊农药中试厂 一种经微生物发酵制得的极细链格孢激活蛋白在农药制剂中的应用
CN105325429A (zh) * 2015-12-07 2016-02-17 陕西西大华特科技实业有限公司 一种含有噻霉酮与抗菌素的杀菌组合物
CN106561720B (zh) * 2016-10-11 2019-04-16 江苏辉丰农化股份有限公司 含苯并异噻唑啉酮类和极细链格孢激活蛋白的杀菌组合物

Also Published As

Publication number Publication date
CN106561720B (zh) 2019-04-16
WO2018068773A3 (fr) 2018-05-31
CN106561720A (zh) 2017-04-19

Similar Documents

Publication Publication Date Title
CN103314968B (zh) 具有增效作用的杀菌组合物
CN101669486B (zh) 一种含苯醚菌酯的杀菌组合物
CN105660659B (zh) 一种杀菌剂组合物
WO2018059606A1 (fr) Composition bactéricide contenant de la benzisothiazolinone et du mandipropamide
WO2018086633A1 (fr) Composition bactéricide comprenant de la benzisothiazolinone et de l'éthylicine
WO2018040775A1 (fr) Composition germicide
WO2018157649A1 (fr) Composition microbicide contenant un dérivé d'émodine et de la benzisothiazolinone
WO2017185559A1 (fr) Composition antimicrobienne
CN106070245B (zh) 一种杀菌剂组合物
WO2017206825A1 (fr) Composition de désherbage à effets synergiques
WO2018036294A1 (fr) Composition pesticide
WO2018126878A1 (fr) Composition fongicide contenant de la benzisothiazolinone et du tétraconazole
CN106212480B (zh) 一种杀菌剂组合物
WO2018024067A1 (fr) Composition fongicide
CN109938045A (zh) 含有极细链格孢激活蛋白和大黄素甲醚的农药组合物
WO2018006462A1 (fr) Composition fongicide
CN106561720A (zh) 含苯并异噻唑啉酮类和极细链格孢激活蛋白的杀菌组合物
WO2018001152A1 (fr) Composition bactéricide
WO2018068772A1 (fr) Composition bactéricide contenant de la benzisothiazolinone et de l'amétoctradine
WO2018040788A1 (fr) Composition germicide
WO2018054396A1 (fr) Composition bactéricide
CN102318641B (zh) 含有稻瘟酰胺的杀菌组合物
CN106172437B (zh) 一种杀菌剂组合物
WO2018036302A1 (fr) Composition fongicide
WO2018000526A1 (fr) Composition fongicide

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 17860173

Country of ref document: EP

Kind code of ref document: A2

NENP Non-entry into the national phase in:

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 17860173

Country of ref document: EP

Kind code of ref document: A2