WO2019000067A1 - Composition cosmétique de correction du teint de la peau, utilisation d'une composition cosmétique et procédé de correction du teint de la peau dans un environnement urbain - Google Patents

Composition cosmétique de correction du teint de la peau, utilisation d'une composition cosmétique et procédé de correction du teint de la peau dans un environnement urbain Download PDF

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Publication number
WO2019000067A1
WO2019000067A1 PCT/BR2018/050215 BR2018050215W WO2019000067A1 WO 2019000067 A1 WO2019000067 A1 WO 2019000067A1 BR 2018050215 W BR2018050215 W BR 2018050215W WO 2019000067 A1 WO2019000067 A1 WO 2019000067A1
Authority
WO
WIPO (PCT)
Prior art keywords
skin
extract
composition according
skin tone
cosmetic composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/BR2018/050215
Other languages
English (en)
Portuguese (pt)
Inventor
Patricia DONIZETI GERALDINI
Viviane POLDOUF QUEIJA
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Natura Cosmeticos SA
Original Assignee
Natura Cosmeticos SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Natura Cosmeticos SA filed Critical Natura Cosmeticos SA
Publication of WO2019000067A1 publication Critical patent/WO2019000067A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/678—Tocopherol, i.e. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9728—Fungi, e.g. yeasts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
    • A61Q1/02—Preparations containing skin colorants, e.g. pigments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin

Definitions

  • COSMETIC COMPOSITION OF SKIN TISSUE CORRECTION USE OF A COSMETIC COMPOSITION AND METHOD OF CORRECTION OF SKIN TISSUE IN THE URBAN ENVIRONMENT.
  • the present invention relates to cosmetic skin tone correction compositions comprising an antioxidant complex and conditioning agent (s), in the form of a Color Control Cream (or "Color Control Cream” CC Cream "), with an urban approach, which provides effects of cellular detoxification, cellular oxygenation, antioxidant, anti-pollution, anti-stress and barrier fortification, particularly through the mechanisms of AhR, HIF-1a and LC3.
  • an antioxidant complex and conditioning agent s
  • an urban approach which provides effects of cellular detoxification, cellular oxygenation, antioxidant, anti-pollution, anti-stress and barrier fortification, particularly through the mechanisms of AhR, HIF-1a and LC3.
  • Cosmetic compositions have been widely researched and assembled a number of products with diverse and specific purposes within the beautification process.
  • “Color Control Cream” or “CC Cream” are multifunctional products, aimed at neutralizing possible imperfections related to skin tone, such as pallor, redness, opacity and well-being. as providing additional benefits such as hydration and sun protection. In general, they are able to replace the traditional primer and base, and can even be used alone in a makeup and care process.
  • Exposure to environmental factors, including air pollution, smoking, and ultraviolet radiation are responsible for four skin conditions that leave it in a stress condition and lack of radiance:
  • HyR - Damage receptors
  • Figure 1 shows the in vitro efficacy in the AhR marker, where * : significant result according to Student t test / non-polluted / polluted control (P ⁇ 0.05).
  • Figure 2 shows the in vitro efficacy in the synthesis of LC3, where * : significant result according to Student's t test / normal cells / "autophagy-induced” control (P ⁇ 0.05).
  • Figure 3 shows the in vitro efficacy in the induction of HIF-1a, where * : significant result according to Student's t test / normal / control / aged fibroblasts (P ⁇ 0.05).
  • Figure 5 shows the result of the image analysis based on photographs, evaluated in 20 volunteers, to verify the uniformity of skin tone and reduction of periorbital hyperpigmentation after 15 minutes of application of the product (immediate disguise).
  • the present invention relates to cosmetic skin tone correction compositions
  • an antioxidant complex and conditioning agent in the form of a Color Control Cream (or "Color Control Cream” CC cream "), with an urban approach, which provides effects of cell detoxification, cellular oxygenation, antioxidant, anti-pollution, anti-stress and barrier fortification, particularly through the mechanisms of AhR, HIF-1a and LC3.
  • the antioxidant complex is particularly comprised of tocopheryl acetate, Theobroma Cacao extract and Camellia Sinesis extract.
  • the conditioning agent (s) are (are) selected, in particular from Candida Saitoana hydrolyzed extract, hydrolyzed rice protein and / or Tropaeolum Majus extract or combination thereof.
  • compositions of the prior art offer anti-pollution and skin anti-stress efficacy through the activation of skin receptors causing damage by environmental factors.
  • these compositions act in the skin promoting the cleaning, oxygenation, daily defense against the generation of free radicals and removing the impurities resulting from the daily aggressions, forming a barrier that protects the skin from the damages caused by the aggressions of the environment. It is observed a detox / purification action of the skin, as well as fortification, which increases its resistance.
  • compositions according to the present invention are intended to achieve a perfect-looking skin, by removing the natural tone of the skin, leaving the tired, greyish and stained appearance to give rise to radiant skin and naturally perfect.
  • This benefit is achieved by the use of reflective particles and pigments that uniform the skin tone, correcting imperfections, ensuring complete correction. The result is healthy, naturally radiant skin.
  • the application of the compositions according to the present invention provides immediate and 24 hour hydration and protection against UVB / UVA rays.
  • the developed cosmetic form In addition to bringing the innovative texture of ultralight facial oil suitable for the skin, the developed cosmetic form, through a lipidization process, enhances the sensory properties, leaving the skin immediately soft and velvety.
  • the present invention relates to the novel cosmetic skin tone correction composition
  • the novel cosmetic skin tone correction composition comprising:
  • antioxidant complex consisting of tocopheryl acetate, Theobroma Cacao extract and Camellia Sinesis extract;
  • conditioning agent selected from Candida Saitoana hydrolyzed extract, hydrolyzed rice protein and / or Tropaeolum Majus extract, or a combination thereof, particularly about 0.1% a about 5% hydrolyzed extract of Candida Saitoana, about 0.1% to about 5% hydrolyzed rice protein and about 0.1% to about 10% Tropaeolum Majus extract, more particularly about 2% % hydrolyzed extract of Candida Saitoana, about 1.5% of hydrolyzed rice protein and about 3% of Tropaeolum Majus extract; and c) cosmetically acceptable excipients.
  • conditioning agent selected from Candida Saitoana hydrolyzed extract, hydrolyzed rice protein and / or Tropaeolum Majus extract, or a combination thereof, particularly about 0.1% a about 5% hydrolyzed extract of Candida Saitoana, about 0.1% to about 5% hydrolyzed rice protein and about 0.1% to about 10% Tropaeolum Majus extract, more particularly about 2% % hydrolyzed extract
  • compositions according to the present invention comprise from about 0.1% to about 5% reflecting particles and pigments, for example, sensory modifying particles and optical diffusers selected from polymethylsilsesquioxane, silica and / or boron nitride and / or about 0.1% to about 5% selected pearlescent particles of titanium dioxide, mica, iron oxide and / or tin oxide and / or about 0.1% to about 10% of sunscreen selected from ethylhexylmethoxycinnamate, diethylaminohydroxybenzoylhexyl benzoate, methylene bis-benzotriazolyl tetramethylbutylphenol, bis-ethylhexyloxyphenol methoxyphenyl triazine, titanium dioxide and / or silica.
  • sensory modifying particles and optical diffusers selected from polymethylsilsesquioxane, silica and / or boron nitride and / or about 0.1% to about 5% selected pearlescent particles of titanium dioxide
  • Cosmetically acceptable excipients (c) include, without limitation, those known in the art, e.g. emulsifiers, fragrances, pH adjusters, antioxidants of the formulation, chelating agents and / or preservatives.
  • cosmetically acceptable excipients comprise triacontanyl polyvinyl pyrrolidone (PVP), isoamyl cocoate, dimethicone, caprylyl methacone, dicaprylyl carbonate, murumuru butter, polyglyceryl-10 pentastearate / behenyl alcohol / sodium stearoyl lactylate, glyceryl stearate / PEG-100 stearate, tribehenin / glyceryl behenate / dibehenate, CI77491 / red iron oxide, CI77492 / yellow iron oxide, CI77499 / black iron oxide, CI77891 / titanium dioxide, xanthan gum, triglyceride (VP) copolymer / trilau-reth-4 phosphate / polyglyceryl-2-sesquiisostearate, glycerol, triethanolamine, BHT, disodium EDTA
  • PVP polyvinyl
  • the present invention contemplates the use of the cosmetic composition in the manufacture of a skin tone correction cream for performance in the AhR, HIF-1a and LC3 mechanisms, as well as in the manufacture of a correction cream of skin tone with simultaneous effects of cellular detoxification, cellular oxygenation, antioxidant, antipollution and skin barrier fortification, urban approach.
  • the present invention contemplates an urban skin tone correction method which comprises applying to the skin a cosmetic composition in accordance with the present invention.
  • Example 1 Composition according to the present invention - preferred embodiment
  • the test was performed by Western blotting.
  • the present invention significantly acted on the synthesis of LC3, a specific marker of autophagosomes, in 38%.
  • the autophagic activity of the initially titrated cells was increased by moderate dose of H202.
  • Cells normal human fibroblasts, aged human fibroblasts obtained by successive transfers.
  • HIF-1a is significantly reduced by 44% in aged human fibroblasts compared to normal human fibroblasts.
  • the present invention significantly restored the induction of HIF-1 to aged fibroblasts by 63% compared to normal human fibroblasts.
  • This benefit was evaluated by means of a noninvasive objective methodology called corneometry, which evaluates the amount of water added to the surface of the skin with the use of the product through the evaluation of the electrical conductivity of the skin surface.
  • corneometry evaluates the amount of water added to the surface of the skin with the use of the product through the evaluation of the electrical conductivity of the skin surface.
  • measurements were made before application of the product to obtain information about the initial state of the skin, and after 15 minutes, 2 hours, 4 hours, 8 hours, and 24 hours of application of the product to identify the improvement of hydration product provides the skin, both immediately after use, and throughout the day.
  • the applications are made in the region of the forearm, which are regions that present smaller interferences of external factors and are more protected of the solar expositions.
  • composition of the present invention showed moisturizing performance within 24 hours after application thereof.
  • TEWL Transepidermal Water Loss
  • the applications were made in the forearm region, which are regions that have less interference from external factors and are more protected from solar exposures. Significantly positive effects of barrier fortification were obtained at all evaluated times.
  • the percentage of barrier fortification afforded by the product of the invention when compared to the initial state of the skin is as follows:
  • the investigational product applied on the skin of the volar forearm, gave a significant effect of fortification of the skin barrier after 28 days of home use, when compared to the control (skin without application of any products ).
  • the percentage value obtained from fortification of the skin barrier was 13.5% after 28 days of home use, in relation to the initial skin condition and control. 76.9% of the research participants presented fortification of the cutaneous barrier after home use of the research product.

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Cosmetics (AREA)

Abstract

La présente invention concerne des compositions cosmétiques de correction du teint de la peau, comprenant un complexe antioxydant et une ou plusieurs agents conditionneurs, sous la forme d'une crème de correction du teint de la peau (ou « Color Control Cream » ou « CC cream »), à utiliser notamment en milieu urbain, produisant des effets de détoxication cellulaire, d'oxygénation cellulaire, antioxydant, antipollution et renforçateur de barrière, notamment par action sur les mécanismes de AhR, HIF-1α e LC3.
PCT/BR2018/050215 2017-06-30 2018-06-29 Composition cosmétique de correction du teint de la peau, utilisation d'une composition cosmétique et procédé de correction du teint de la peau dans un environnement urbain Ceased WO2019000067A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
BR102017014319A BR102017014319A2 (pt) 2017-06-30 2017-06-30 composição cosmética de correção de tom de pele, uso de uma composição cosmética e método de correção de tom de pele em ambiente urbano
BRBR1020170143198 2017-06-30

Publications (1)

Publication Number Publication Date
WO2019000067A1 true WO2019000067A1 (fr) 2019-01-03

Family

ID=64740264

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/BR2018/050215 Ceased WO2019000067A1 (fr) 2017-06-30 2018-06-29 Composition cosmétique de correction du teint de la peau, utilisation d'une composition cosmétique et procédé de correction du teint de la peau dans un environnement urbain

Country Status (3)

Country Link
AR (1) AR112262A1 (fr)
BR (1) BR102017014319A2 (fr)
WO (1) WO2019000067A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020165553A1 (fr) 2019-02-13 2020-08-20 Block Container Systems Limited Équipement et unité de coin
WO2025137031A1 (fr) * 2023-12-18 2025-06-26 L'oreal Compositions contenant de la bis-éthylhexyloxyphénol méthoxyphényl triazine et un système antioxydant

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006053415A1 (fr) * 2004-11-18 2006-05-26 Biopharmacopae Design International Inc. Extraits de plantes et leurs utilisations en dermatologie
FR2965483A1 (fr) * 2010-10-04 2012-04-06 Silab Sa Utilisation cosmetique d'un extrait de tropaeolum majus comme principe actif pour favoriser l'oxygenation du tissu cutane
WO2014043009A1 (fr) * 2012-09-14 2014-03-20 Elc Management Llc Méthode et compositions destinées à améliorer le catabolisme sélectif dans des cellules de surfaces kératiniques
WO2015164657A1 (fr) * 2014-04-23 2015-10-29 Bcs Business Consulting Services Pte Ltd Incorporation de composant(s) soluble(s) dans l'eau dans des formulations anhydres
JP2016044171A (ja) * 2014-08-25 2016-04-04 株式会社 Ｉｔｏ Ｒｅｓｅｒｃｈ 新規化合物及びその配合組成物
US9849077B2 (en) * 2014-03-10 2017-12-26 Mary Kay Inc. Skin lightening compositions

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006053415A1 (fr) * 2004-11-18 2006-05-26 Biopharmacopae Design International Inc. Extraits de plantes et leurs utilisations en dermatologie
FR2965483A1 (fr) * 2010-10-04 2012-04-06 Silab Sa Utilisation cosmetique d'un extrait de tropaeolum majus comme principe actif pour favoriser l'oxygenation du tissu cutane
WO2014043009A1 (fr) * 2012-09-14 2014-03-20 Elc Management Llc Méthode et compositions destinées à améliorer le catabolisme sélectif dans des cellules de surfaces kératiniques
US9849077B2 (en) * 2014-03-10 2017-12-26 Mary Kay Inc. Skin lightening compositions
WO2015164657A1 (fr) * 2014-04-23 2015-10-29 Bcs Business Consulting Services Pte Ltd Incorporation de composant(s) soluble(s) dans l'eau dans des formulations anhydres
JP2016044171A (ja) * 2014-08-25 2016-04-04 株式会社 Ｉｔｏ Ｒｅｓｅｒｃｈ 新規化合物及びその配合組成物

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020165553A1 (fr) 2019-02-13 2020-08-20 Block Container Systems Limited Équipement et unité de coin
WO2025137031A1 (fr) * 2023-12-18 2025-06-26 L'oreal Compositions contenant de la bis-éthylhexyloxyphénol méthoxyphényl triazine et un système antioxydant

Also Published As

Publication number Publication date
BR102017014319A2 (pt) 2019-01-15
AR112262A1 (es) 2019-10-09

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