WO2019057937A3 - Unité de robinet pour appareil de chromatographie - Google Patents

Unité de robinet pour appareil de chromatographie Download PDF

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Publication number
WO2019057937A3
WO2019057937A3 PCT/EP2018/075694 EP2018075694W WO2019057937A3 WO 2019057937 A3 WO2019057937 A3 WO 2019057937A3 EP 2018075694 W EP2018075694 W EP 2018075694W WO 2019057937 A3 WO2019057937 A3 WO 2019057937A3
Authority
WO
WIPO (PCT)
Prior art keywords
fluid
valve unit
pair
chromatography apparatus
coupled
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2018/075694
Other languages
English (en)
Other versions
WO2019057937A2 (fr
Inventor
Lars Olof Nils ROSENGREN
Kerstin Elisabet ERICKSON
Tim FRANCOIS
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Global Life Sciences Solutions USA LLC
Original Assignee
GE Healthcare Bio Sciences Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GE Healthcare Bio Sciences Corp filed Critical GE Healthcare Bio Sciences Corp
Priority to CN201880075460.7A priority Critical patent/CN111373255A/zh
Priority to US16/648,296 priority patent/US11703483B2/en
Priority to EP25159049.3A priority patent/EP4534169A3/fr
Priority to JP2020516661A priority patent/JP7278268B2/ja
Priority to EP18779605.7A priority patent/EP3685155B1/fr
Priority to CN202510258898.0A priority patent/CN120100935A/zh
Publication of WO2019057937A2 publication Critical patent/WO2019057937A2/fr
Publication of WO2019057937A3 publication Critical patent/WO2019057937A3/fr
Anticipated expiration legal-status Critical
Priority to US18/326,838 priority patent/US20230304974A1/en
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K11/00—Multiple-way valves, e.g. mixing valves; Pipe fittings incorporating such valves
    • F16K11/10—Multiple-way valves, e.g. mixing valves; Pipe fittings incorporating such valves with two or more closure members not moving as a unit
    • F16K11/20—Multiple-way valves, e.g. mixing valves; Pipe fittings incorporating such valves with two or more closure members not moving as a unit operated by separate actuating members
    • F16K11/22—Multiple-way valves, e.g. mixing valves; Pipe fittings incorporating such valves with two or more closure members not moving as a unit operated by separate actuating members with an actuating member for each valve, e.g. interconnected to form multiple-way valves
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K31/00—Actuating devices; Operating means; Releasing devices
    • F16K31/02—Actuating devices; Operating means; Releasing devices electric; magnetic
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K7/00—Diaphragm valves or cut-off apparatus, e.g. with a member deformed, but not moved bodily, to close the passage ; Pinch valves
    • F16K7/12—Diaphragm valves or cut-off apparatus, e.g. with a member deformed, but not moved bodily, to close the passage ; Pinch valves with flat, dished, or bowl-shaped diaphragm
    • F16K7/14—Diaphragm valves or cut-off apparatus, e.g. with a member deformed, but not moved bodily, to close the passage ; Pinch valves with flat, dished, or bowl-shaped diaphragm arranged to be deformed against a flat seat
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/16—Injection
    • G01N30/20—Injection using a sampling valve
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N30/42—Flow patterns using counter-current
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N30/46—Flow patterns using more than one column
    • G01N30/468—Flow patterns using more than one column involving switching between different column configurations
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1814—Recycling of the fraction to be distributed
    • B01D15/1821—Simulated moving beds
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/16—Injection
    • G01N30/20—Injection using a sampling valve
    • G01N2030/201—Injection using a sampling valve multiport valves, i.e. having more than two ports
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/16—Injection
    • G01N30/20—Injection using a sampling valve
    • G01N2030/205—Diaphragm valves, e.g. deformed member closing the passage
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N2030/382—Flow patterns flow switching in a single column
    • G01N2030/385—Flow patterns flow switching in a single column by switching valves

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)

Abstract

La présente invention concerne une unité de robinet pour un appareil de chromatographie, l'unité de robinet comprenant une entrée de fluide configurée pour recevoir un fluide d'entrée, une sortie de fluide configurée pour fournir un fluide de sortie, une première paire d'orifices de fluide configurés pour être raccordés à une première colonne, une seconde paire d'orifices de fluide configurés pour être raccordés à une seconde colonne, un ensemble robinet de raccordement configuré pour diriger un fluide au choix vers l'entrée de fluide, la sortie de fluide, la première paire d'orifices de fluide et la seconde paire d'orifices de fluide en réponse à un ou plusieurs signaux de commande, l'ensemble robinet de raccordement étant configuré pour diriger un fluide à l'aide d'une sélection de robinets à membrane raccordés par des canaux de fluide compris dans un corps de l'ensemble robinet de raccordement. L'invention concerne en outre un appareil de chromatographie comprenant l'unité de robinet et un robinet à membrane contenu dans l'unité de robinet.
PCT/EP2018/075694 2017-09-22 2018-09-21 Unité de robinet pour appareil de chromatographie Ceased WO2019057937A2 (fr)

Priority Applications (7)

Application Number Priority Date Filing Date Title
CN201880075460.7A CN111373255A (zh) 2017-09-22 2018-09-21 用于色谱设备的阀单元
US16/648,296 US11703483B2 (en) 2017-09-22 2018-09-21 Valve unit for a chromatography apparatus
EP25159049.3A EP4534169A3 (fr) 2017-09-22 2018-09-21 Unité de soupape pour un appareil de chromatographie
JP2020516661A JP7278268B2 (ja) 2017-09-22 2018-09-21 クロマトグラフィ装置のための弁ユニット
EP18779605.7A EP3685155B1 (fr) 2017-09-22 2018-09-21 Valve pour appareil de chromatographie
CN202510258898.0A CN120100935A (zh) 2017-09-22 2018-09-21 用于色谱设备的阀单元
US18/326,838 US20230304974A1 (en) 2017-09-22 2023-05-31 Valve Unit for a Chromatography Apparatus

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB1715399.0 2017-09-22
GBGB1715399.0A GB201715399D0 (en) 2017-09-22 2017-09-22 Valve unit for a chromatography apparatus

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US16/648,296 A-371-Of-International US11703483B2 (en) 2017-09-22 2018-09-21 Valve unit for a chromatography apparatus
US18/326,838 Continuation US20230304974A1 (en) 2017-09-22 2023-05-31 Valve Unit for a Chromatography Apparatus

Publications (2)

Publication Number Publication Date
WO2019057937A2 WO2019057937A2 (fr) 2019-03-28
WO2019057937A3 true WO2019057937A3 (fr) 2019-05-16

Family

ID=60244488

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2018/075694 Ceased WO2019057937A2 (fr) 2017-09-22 2018-09-21 Unité de robinet pour appareil de chromatographie

Country Status (6)

Country Link
US (2) US11703483B2 (fr)
EP (2) EP4534169A3 (fr)
JP (1) JP7278268B2 (fr)
CN (2) CN120100935A (fr)
GB (1) GB201715399D0 (fr)
WO (1) WO2019057937A2 (fr)

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GB202105909D0 (en) * 2021-04-26 2021-06-09 Cytiva Sweden Ab Gb2105909.2
GB202105923D0 (en) * 2021-04-26 2021-06-09 Cytiva Sweden Ab Reconfigurable bioprocessing systems
USD1091858S1 (en) * 2024-01-29 2025-09-02 Inventage Lab Inc. Lipid nanoparticle preparation device

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EP1775001A1 (fr) * 2005-10-13 2007-04-18 Xendo Holding B.V. Dispositif pour séparations chromatographiques
WO2008048395A1 (fr) * 2006-08-30 2008-04-24 Semba Biosciences, Inc. Module de valve pour chromatographie à lit mobile simulé

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Also Published As

Publication number Publication date
WO2019057937A2 (fr) 2019-03-28
CN120100935A (zh) 2025-06-06
CN111373255A (zh) 2020-07-03
EP3685155C0 (fr) 2025-08-06
JP7278268B2 (ja) 2023-05-19
JP2020534538A (ja) 2020-11-26
US11703483B2 (en) 2023-07-18
EP3685155A2 (fr) 2020-07-29
EP4534169A3 (fr) 2025-07-02
EP4534169A2 (fr) 2025-04-09
US20200284767A1 (en) 2020-09-10
GB201715399D0 (en) 2017-11-08
US20230304974A1 (en) 2023-09-28
EP3685155B1 (fr) 2025-08-06

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